scholarly journals Effect of propofol on the haematological profile of pregnant Red Sokoto does

2019 ◽  
pp. 37-40
Keyword(s):  
General Anaesthesia ◽  
Jugular Vein ◽  
Small Animal ◽  
Rapid Onset ◽  
Blood Parameters ◽  
Duration Of Action ◽  
Blood Samples ◽  
Anaesthetic Agents ◽  
Haematological Profile ◽  
Apparently Healthy

Introduction: Propofol (Diprivan®) is now a mainstay drug during anaesthesia in human and small animal surgeries and this is as a result of its good quality anaesthesia, rapid onset, and short duration of action with rapid recoveries. There is paucity of information in Nigeria as per the use of general anaesthesia to carry out procedures in pregnant red Sokoto Does. The aim of this study is to assess the haematological profile of pregnant red Sokoto doe following propofol anaesthesia and also ascertain the safety of the drug during gestation. Methods: Ten apparently healthy pregnant Red Sokoto does were used for this study. The animals were acclimatised for two weeks and pregnancy was diagnosed using B-mode Real time® transcutaneous ultrasonography. The animals were grouped into two (A and B) comprising five animals each in their first and second trimesters respectively. Propofol at 4 mg/kg and 5 mg/kg was administered to the does in groups A and B respectively. Blood samples were collected via the jugular vein and analysed using full automated blood counter (Ehmma® PCE 210). Results: The result showed that the onset and duration of propofol anaesthesia at the two doses in both groups were smooth and rapid without much excitation. There were no significant (p < 0.05) differences in the blood parameters in both group when compared with the control. Significance: Our study lends credence to the fact that propofol anaesthesia is suitable and safe anaesthetic agents for induction and maintenance of general anaesthesia in pregnant red Sokoto does.

Association of Retained Fetal Membranes with Haematological Profile in Crossbred Cows

2017 ◽  
Vol 12 (3) ◽  
Author(s):  
K. Rokde ◽  
S. Kumar ◽  
A. Bhardwaz ◽  
S. S. Mahour ◽  
S. P. Nema ◽  
...  
Keyword(s):  
Eosinophil Count ◽  
Jugular Vein ◽  
Dairy Farm ◽  
Fetal Membranes ◽  
Monocyte Count ◽  
Blood Samples ◽  
Mean Values ◽  
Crossbred Cows ◽  
Haematological Profile ◽  
The Mean

This study was carried out on clinical cases of retained fetal membranes in crossbred cows presented at College Clinics and College dairy farm and from Villages in and around Mhow. The blood samples were collected from jugular vein just before 12 hr. postpartum and on 7th day postpartum. Haematological profile revealed that the mean values of haemoglobin, neutrophil and monocyte count after 12 hrs and 7th day postpartum were significantly lower and lymphocyte count was significantly higher in RFM cows (n=18) than normally calved cows (n=6). The differences in mean TLC, eosinophil and basophil counts were non-significant at 12 hrs postpartum, however on 7th day postpartum the TLC and eosinophil count were significantly higher and basophil count was non-significantly different in RFM cows than the normally calved cows.

scholarly journals Comparison of the Effects of Isoflurane and Sevoflurane General Anaesthesia after Induction by Propofol on Clinical and Physiological Measurements in Calves

2019 ◽  
Vol 47 (1) ◽  
Author(s):  
Selvinaz Yakan ◽  
Ozgur Aksoy
Keyword(s):  
Blood Pressure ◽  
Blood Cell ◽  
General Anaesthesia ◽  
Blood Parameters ◽  
P Wave ◽  
Physiological Measurement ◽  
Inhalation Anaesthesia ◽  
Induction Periods ◽  
Anaesthetic Agents ◽  
Physiological Limits

Background: In veterinary surgical operations for cats and dogs, inhalation anaesthesia is known to be a good option for general anaesthesia in long operations or emergency cases. Studies have revealed that during inhalation anaesthesia, the heart and respiratory functions of the animals are more stable compared to injectable anaesthesia. However, there are few studies performed with the use of inhalation anaesthesia in ruminants. In this research, the goal is to evaluate the effects of isoflurane and sevoflurane after induction with propofol in calves based on clinical and physiological parameters and to find a more reliable strategy for general anaesthesia in ruminants.Materials, Methods & Results: The research was carried out on 30 calves, from new-born up to 3-months-old, undergoing surgery operation. Each group consisted of 15 animals that were divided as isoflurane and sevoflurane. For premedication, atropine was administered at a dose of 0.04 mg/kgvia subcutaneous injection in calves. For induction, 15 min after atropine application, propofol was given at 5-6 mg/kgvia intravenous infusion. Then, endotracheal intubation was performed and inhalation anaesthesia began at 5 min after induction. In the isoflurane group, the onset of anaesthesia concentration was set to 3-5% and the maintenance was set to a concentration of 1.5-3%. In the sevoflurane group, the onset of anaesthesia concentration was set to 5-7% and the maintenance was set to a concentration of 2.5-4%. To monitor the calves, the heart rate (HR), the pulse rate (PR), the systolic blood pressure (SBP), diastolic blood pressure (DBP), the respiratory rate (RR), the rectal temperature (RT) and the electrocardiogram (ECG) measurements were recorded before anaesthesia, the premedication, the induction periods, at 5, 15, 30, 45, 60, and 75 min after the onset of inhalation anaesthesia during the operation period. Blood samples were taken before anaesthesia, premedication, induction periods, at 30 and 75 min during the operation and the red blood cell (RBC) count, white blood cell (WBC) count, the amount of haemoglobin (HGB), the haematocrit concentration (HCT), and the platelet (PLT) count were evaluated. Based on the findings, isoflurane and sevoflurane suppressed the cardiovascular system minimally. Both anaesthetic agents caused decreases that did not exceed the physiological limits compared to the measurements taken before the initiation of anaesthesia. Although no significant differences were detected between the groups (P > 0.05) at clinical parameters, the RT differences were regarded as statistically significant according to the measurements that were taken before anaesthesia at all measurement times (P < 0.05). In both groups, the changes that occurred in the P wave, the PR interval, and in the QRS, R and T waves remained within the reference values given in the literature. Both anaesthetic agents have similar effects on the ECG. The dramatic no changes throughout anaesthesia in terms of the amount of HGB and HCT, the RBC, the WBC, and the PLT were not statistically significant, which may be associated with good tissue perfusion.Discussion: Since no serious complications occurred with either anaesthetic option, we have concluded that isoflurane and sevoflurane have similar effects on the cardiopulmonary systems of calves. In addition, the effects of propofol, which is used for induction, have been evaluated and observed and this drug is an effective and reliable option to initiate inhalation anaesthesia. The research on the use of this anaesthetic in calves is limited and most of the existing studies investigated its combination with injectable anaesthetics. As a result, in this research, we concluded that isoflurane and sevoflurane induce similar physiological measurement results, blood parameters, and ECG results and that both anaesthetics cause minimal complications.

scholarly journals Stereotypical behaviour at high yielding dairy cows farms - "tongue rolling"

2013 ◽  
Vol 67 (5-6) ◽  
pp. 349-357
Author(s):  
Radisa Prodanovic ◽  
Danijela Kirovski ◽  
Ivan Vujanac ◽  
Ksenija Nesic ◽  
Aleksandar Janevski ◽  
...  
Keyword(s):  
Dairy Cows ◽  
Total Bilirubin ◽  
Jugular Vein ◽  
Blood Parameters ◽  
Behavioral Disorder ◽  
Housing Type ◽  
Animal Group ◽  
Blood Samples ◽  
Physiological Limit ◽  
Physiological Values

The objective of this work was to determine if there was a connection between stereotypical behaviour of high yielding dairy cows breeds and values of biochemical blood parameters. The investigation was carried out in august at loose-housing type of farms, in 30 heads of cattle from four groups: drying (15 to 7 days before calving), puerperium (up to 40 days after calving, early lactation (up to 120 days after calving) and late lactation (200 to 300 days after calving). Assessment of stereotypical behaviour (tongue rolling) was carried out by the method of careful observation of all the tested animals 2 to 4 hours after morning feeding. Blood samples were taken by puncture of jugular vein from 8 cows out of each animal group. In these blood samples there was determined the concentration of glucose, beta hydroxy-butyric acid (BHBA), total protein (TP), albumin, urea, total bilirubin (TBI), Ca, P, and Mg as well as AST and ALT activities. During the period up to 40 days after calving (puerperium), behavioral disorder in the form of ?tongue rolling? was found out in 4 out of 30 observed animals (13.33%). Average concentrations of all the tested blood parameters during the drying period as well as in early and late lactation were within physiological values for cattle. During puerperium there were found significantly lower values of glycaemia, proteinemia, albuminemia, uremia and magnesiemia in regard to antepartal values (p<0.05), where the values of glycaemia and magnesiemia were below the physiological limit. A the same time, in this group of cows the values of TBI and AST activities were higher than physiological values. Frequent appearance of ?tongue rolling? phenomenon only among cows in the group with deviation of biochemical parameters values, points out to a possible connection between the stereotypical behaviour and biochemical composition of blood. It seems that hypomagnesiemia could be a significant etiopathogenetic factor causing the change in behaviour of cows in intensive livestock production.

scholarly journals Serum testosterone concentration in surgically castrated Black Bengal goats

2018 ◽  
Vol 33 (2) ◽  
pp. 71-77 ◽  
Author(s):  
M Hasan ◽  
MAH Miah ◽  
TA Rosy ◽  
PK Jha ◽  
NS Juyena
Keyword(s):  
Spermatic Cord ◽  
Jugular Vein ◽  
Serum Testosterone ◽  
Capra Hircus ◽  
Tunica Vaginalis ◽  
Blood Samples ◽  
Testosterone Concentration ◽  
Group A ◽  
Group B ◽  
Apparently Healthy

The experiment was carried out to detect the blood serum testosterone concentration after orchiectomy in Black Bengal bucks (Capra hircus). Twelve apparently healthy bucks of 8 - 10 months old were randomly divided into two groups. Group A were castrated surgically through open uncover method and group B remained intact. Local analgesia (2% lidocaine hydrochloride) @ 0.5 mL per spermatic cord and 0.5 mL at the tip of each scrotum were applied initially in all bucks. After aseptic preparation, incision was given at the tip of the scrotum and tunica vaginalis was incised to exteriorize the testis. Anchoring was done at the spermatic cord followed by orchiectomy. The scrotal raphe was incised to reach the other testis and the same procedure was followed. Blood samples were collected from jugular vein before orchiectomy and on day 30. In the castrated bucks, serum testosterone concentration was significantly (P<0.01) decreased from day 0 (6.1 ± 0.2 ng/mL) to day 30 (0.6 ± 0.0 ng/mL), which confirmed the efficacy of castration.Bangl. vet. 2016. Vol. 33, No. 2, 71-77

▾ Alfentanil in anaesthesia

1986 ◽  
Vol 24 (13) ◽  
pp. 51-52
Keyword(s):  
General Anaesthesia ◽  
Short Duration ◽  
Bolus Injection ◽  
Opioid Analgesic ◽  
Rapid Onset ◽  
Duration Of Action

Alfentanil (Rapifen - Janssen) is an intravenous opioid analgesic with a rapid onset and short duration of action. It is recommended for use as a bolus injection during short general anaesthesia or by infusion during longer procedures.1,2

scholarly journals Effect of Coriander Seeds (Coriandrum Sativum) on Wool Growth and It's Traits and Some Haematological Traits of Awassi Ewes

2010 ◽  
Vol 34 (2) ◽  
pp. 148-155
Author(s):  
Drgham H. Yousif AL-Zwein
Keyword(s):  
Jugular Vein ◽  
Hemoglobin Concentration ◽  
Blood Parameters ◽  
Wool Fiber ◽  
Feed Additive ◽  
Control Group ◽  
Blood Samples ◽  
Wool Growth ◽  
Physical Traits ◽  
The Right

This study was conducted to find out the effect of coriander seeds as feed additive on some hematological traits and wool growth and it's physical traits of Awassi ewes, blood samples were taken biweekly for blood picture, and wool samples were taken every 2.5 months for wool growth and its physical traits. Eighteen Awassi ewes at the age of 2-3 years were randomly divided equally into three groups (6each ) "body weight was considered".Ewes in the first group kept as control and daily fed on concentrate diet (350 g/ head), while the second group was fed on the same diet contain (2.5%) of coriander seeds, while the third group was fed on same diet contain (5%) of coriander seeds. Also all animals were allowed to graze. Blood samples were taken from jugular vein for blood traits viz (PCV) packed cell volume, (Hb) hemoglobin, (MCHC) mean cell hemoglobin concentration. Wool samples (5×5) cm2 were clipped from the last six ribs of the right chest for measuring wool growth and its traits (creasy and clean wool, samples weights, clean wool ratio, staple and fiber lengths and diameters and wool fiber crimps in 1cm of length). The results of blood parameters revealed that the second and third groups were significantly (p<0.05) recorded higher values in their PCV ,Hb, MCHC during most studied periods compared with the control group ,While the second and third groups were significantly (P<0.05) recorded higher values than the first group (control) in their creasy and clean wool, fiber length, wool fiber crimps, while no differences where existed in other wool physical traits.

Serum Endocrine Profile in Relation to Estrus Synchronization in Surti Does

2018 ◽  
Vol 13 (03) ◽  
Author(s):  
M. M. Chaudhary ◽  
C. T. Khasatiya ◽  
S. B. Patel ◽  
S. S. Chaudhary ◽  
V. B. Atara ◽  
...  
Keyword(s):  
Jugular Vein ◽  
Estrus Synchronization ◽  
Progesterone Concentration ◽  
Serum Progesterone ◽  
Blood Samples ◽  
Group Iii ◽  
Group I ◽  
Endocrine Profile ◽  
Group Ii ◽  
And Control

The serum progesterone and estradiol profiles during synchronization of estrus by buck effect and PGF2α treatments were monitored in Surti does. Total eighteen non-pregnant does selected were evenly divided into 3 groups, 6 does in each group. The does of Group I were teased with a sexuallyactive- apronized buck; and those of Group II were treated with PGF2α, i.e., Inj. Lutalyse® @ 7.5 mg/doe IM twice 11 days apart, while the Group III served as untreated control. Blood samples were collected from all the animals on day 0 (before 1st PGF2α injection), 3rd day (during treatment), 11th day (before 2nd PGF2α injection), 14th day (after treatment) and 40th day (post-service) by jugular vein puncture. The serum separated was stored at -20°C till further analysis. In all the three groups, 83.33% does, conceived at first service in the sampling cycle. The overall mean serum progesterone concentration of Group I does (5.82±0.72 ng/ml) was significantly higher (p less than 0.01) as compared to Group II (2.93±0.38 ng/ml) and III (2.88±0.30 ng/ml). Similarly, the overall mean serum progesterone concentration of Surti does on day 0 (2.65±0.46 ng/ml), 3rd (2.56±0.80 ng/ml), 11th (4.45±0.84 ng/ml) and 14th (3.40±0.63 ng/ml) did not differ significantly, but the overall mean level at day 40 (6.31±0.45 ng/ml) was significantly (p less than 0.01) higher, because most of animals became pregnant at that time. The overall mean serum oestradiol-17β levels of Group I (24.40±2.98 pg/ ml) was significantly higher (p less than 0.01) than in Group II (15.77±1.77 pg/ml) and III (12.21±1.45 pg/ ml). On the other hand, the overall mean serum oestradiol-17β levels of Surti does on day 0 (12.89±1.21 pg/ml), 3rd (15.84±1.74 pg/ml), 11th (14.81±1.96 pg/ml), 14th (22.15±2.97 pg/ml) and 40th (21.64±5.16 pg/ml) did not differ significantly (p>0.05) and the slightly higher overall mean level found at 40th day might be the influence of the non-pregnant does at first service in the cumulative animals. The hormonal profile reflected the initiation of cyclicity and establishment of pregnancy in treated and control animals.

scholarly journals Surrogate Indexes of Insulin Resistance in Dairy Goats: Transitional Variation in Subclinical Hyperketonemia

2021 ◽  
Vol 8 (6) ◽  
pp. 102
Author(s):  
Siqi Liu ◽  
Yezi Kong ◽  
Jing Wen ◽  
Yan Huang ◽  
Yaoquan Liu ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Transition Period ◽  
Jugular Vein ◽  
Metabolic Parameters ◽  
Model Assessment ◽  
Early Lactation ◽  
Homeostasis Model Assessment ◽  
Dairy Goats ◽  
Blood Samples ◽  
Normal Glucose

Background: Dairy goats are highly susceptible to subclinical hyperketonemia (SCHK) during the transition period. This study aimed to compare the variation in metabolic parameters and surrogate indexes of insulin resistance (sIR) between goats with SCHK and clinically healthy (HEAL) goats during the transition period. Methods: Twenty Guanzhong dairy goats were assorted to HEAL (n = 10) and SCHK (n = 10) groups according to the blood β-hydroxybutyrate (BHBA) concentrations. The blood samples were taken from the jugular vein of each goat at −3, −2, −1, 0 (partum), +1, +2, and +3 weeks relative to kidding to analyses GLU and INS. The sIR was calculated from blood metabolic parameters. Results: Compared with the HEAL goats, the insulin concentrations were significantly higher in SCHK goats during the first three weeks postpartum. The QUICKI, revised QUICKI (RQUICKI), and RQUICKIBHBA were significantly lower in goats with SCHK at 1 week postpartum, while the homeostasis model assessment-IR (HOMA-IR) was significantly higher. Conclusion: Goats with SCHK made more efforts through elevated insulin levels at early lactation than HEAL goats, thereby maintaining the normal glucose concentrations.

Automatic blood sampling equipment for use in studies of animal physiology

1998 ◽  
Vol 66 (3) ◽  
pp. 769-775 ◽  
Author(s):  
P. J. Goddard ◽  
G. J. Gaskin ◽  
A. J. Macdonald
Keyword(s):  
Jugular Vein ◽  
Blood Sampling ◽  
Start Time ◽  
Confounding Effect ◽  
Blood Samples ◽  
Animal Physiology ◽  
Vein Catheter ◽  
The Subject ◽  
Large Animals ◽  
Jugular Vein Catheter

AbstractA device for the collection of discrete blood samples from large animals has been developed to allow studies of physiology to be undertaken without the confounding effect of restraint. A microprocessor controlled unit (measuring 180 × 110 × 90 mm), weighing less than 1-2 kg, is mounted on the back of the experimental subject using a simple harness. A sampling line is connected to a previously inserted jugular vein catheter. Samples of blood (approx. 5 ml) are collected at pre-determined times following a start time which can be delayed by up to 48 h to allow the subject to recover from any effects of attachment of the sampler. The results from three studies suggest that the device offers a novel way to overcome a number of difficulties which occur when conventional methods are used to collect blood in experiments.

scholarly journals Intravenous anaesthesia in goats: A review

2013 ◽  
Vol 84 (1) ◽  
Author(s):  
T. Brighton Dzikiti
Keyword(s):  
General Anaesthesia ◽  
Muscle Relaxation ◽  
Scientific Information ◽  
Working Environment ◽  
Total Intravenous Anaesthesia ◽  
Intravenous Anaesthesia ◽  
Anaesthetic Agents ◽  
Inhalation Anaesthetic ◽  
Intravenous Anaesthetic ◽  
Balanced Anaesthesia

Intravenous anaesthesia is gradually becoming popular in veterinary practice. Traditionally, general anaesthesia is induced with intravenous drugs and then maintained with inhalation agents. Inhalation anaesthetic agents cause more significant dose-dependent cardiorespiratory depression than intravenous anaesthetic drugs, creating a need to use less of the inhalation anaesthetic agents for maintenance of general anaesthesia by supplementing with intravenous anaesthesia drugs. Better still, if anaesthesia is maintained completely with intravenous anaesthetic drugs, autonomic functions remain more stable intra-operatively. Patient recovery from anaesthesia is smoother and there is less pollution of the working environment than happens with inhalation anaesthetic agents. Recently, a number of drugs with profiles (pharmacokinetic and pharmacodynamic) suitable for prolonged intravenous anaesthesia have been studied, mostly in humans and, to a certain extent, in dogs and horses. There is currently very little scientific information on total intravenous anaesthesia in goats, although, in the past few years, some scholarly scientific articles on drugs suitable for partial intravenous anaesthesia in goats have been published. This review article explored the information available on drugs that have been assessed for partial intravenous anaesthesia in goats, with the aim of promoting incorporation of these drugs into total intravenous anaesthesia protocols in clinical practice. That way, balanced anaesthesia, a technique in which drugs are included in anaesthetic protocols for specific desired effects (hypnosis, analgesia, muscle relaxation, autonomic stabilisation) may be utilised in improving the welfare of goats undergoing general anaesthesia.

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