scholarly journals Correlation between Serum Level of Vitamin D and Severity Degree of Diabetic Foot Ulcer in Patients with Normal Ankle Brachial Index

Author(s):  
Saleh Harris ◽  
Raden Suhartono ◽  
Aria Kekalih

Introduction: Diabetes mellitus can cause various complications, including diabetic foot ulcers (DFU). Vitamin D levels are known to be correlated with wound healing and insulin resistance. Method: This cross-sectional study aimed to determine the correlation between the serum level of vitamin D and the severity degree of DFU. Thirty DFU patients with normal ankle- brachial index, grouped into degrees according to the Wagner classification, were included in this study. Their serum level of vitamin D was examined using the chemiluminescent immunoassay method. The correlation between these two variables was analyzed. Results: Patients were 18 males (60%) and 12 females (40%) with an average age of 57 years. The average serum level of vitamin D was 10.58 ng/mL. A significant correlation was found between the serum level of vitamin D and the severity of DFU (r= -0.901, p <0.001). Conclusion: The serum level of vitamin D screening in DFU patients was strongly correlated with the degree of DFU. Keywords: diabetes mellitus, diabetic foot ulcer, vitamin D, Wagner classification

2020 ◽  
Vol 16 (3) ◽  
pp. 270-277 ◽  
Author(s):  
Mutasem Ababneh ◽  
Mousab Y. Al Ayed ◽  
Asirvatham A. Robert ◽  
Mohamed A. Al Dawish

Background: This cross sectional study investigated the clinical use of the ankle-brachial index (ABI) and toe brachial index (TBI) in 91 type 2 diabetic foot ulcer patients who visited the diabetic foot clinic, Prince Sultan Military Medical City, Saudi Arabia during July 2017 and January 2018. Materials and Methods: The ABI and TBI facilitated the detection of peripheral arterial disease (PAD) and the patients’ medical records were used to collect the clinical and demographic variables. The variables of duration (p = 0.047) and treatment (p = 0.046) of the ABI showed significant differences. Age (p = 0.034) and duration (p = 0.001) were the factors related to the diagnosis of TBI by the “χ2” test. Results: From the TBI, 26.4% of the patients were found to have PAD, while the ABI showed that 21.8% of patients had the condition. However, no statistical significance was noted. From the regression analysis, the variable duration of diabetes (≥ 20 years of age) was recognized as an independent risk factor for TBI. Conclusion: In conclusion, it is recommended both the ABI and TBI to be used as screening tests for PAD in diabetic foot ulcer patients.


2017 ◽  
Vol 2017 ◽  
pp. 1-8 ◽  
Author(s):  
Tesfamichael G. Mariam ◽  
Abebaw Alemayehu ◽  
Eleni Tesfaye ◽  
Worku Mequannt ◽  
Kiber Temesgen ◽  
...  

Diabetes mellitus is a metabolic disorder which is characterized by multiple long-term complications that affect almost every system in the body. Foot ulcers are one of the main complications of diabetes mellitus. However, there is limited evidence on the occurrence of foot ulcer and influencing factors in Ethiopia. An institutional-based cross-sectional study was conducted in Gondar University Hospital, Ethiopia, to investigate foot ulcer occurrence in diabetic patients. Systematic random sampling was used to select 279 study participants. Bivariate and multivariable logistic regression model was fitted to identify factors associated with diabetic foot ulcer. Odds ratio with 95% confidence interval was computed to determine the level of significance. Diabetic foot ulcer was found to be 13.6%. Rural residence [AOR = 2.57; 95% CI: 1.42, 5.93], type II diabetes mellitus [AOR = 2.58; 95% CI: 1.22, 6.45], overweight [AOR = 2.12; 95% CI: 1.15, 3.10], obesity [AOR = 2.65; 95% CI: 1.25, 5.83], poor foot self-care practice [AOR = 2.52; 95% CI: 1.21, 6.53], and neuropathy [AOR = 21.76; 95% CI: 8.43, 57.47] were factors associated with diabetic foot ulcer. Diabetic foot ulcer was found to be high. Provision of special emphasis for rural residence, decreasing excessive weight gain, managing neuropathy, and promoting foot self-care practice would decrease diabetic foot ulcer.


2019 ◽  
Vol 47 (2) ◽  
pp. 3-16
Author(s):  
Patrianef Darwis ◽  
Bakti H Simanjuntak ◽  
Grace Wangge ◽  
Deddy Pratama ◽  
Ahmad Bakri ◽  
...  

Background. Foot ulcer is one of the most common complications in diabetes mellitus patients. This condition prolongs hospital length of stay (LOS) and increases hospitalization cost. This study aims to assess factors that affect the LOS in patients with the mentioned condition. Methods. This is a retrospective cohort study of diabetes mellitus patients with foot ulcer who were hospitalized in Cipto Mangunkusumo General Hospital from January 2015 to April 2016. There were 120 patients recruited and then divided into two groups according to their hospitalization duration, which was short and long. Univariate analysis was conducted in predicted factors including gender, ankle-brachial index, ulcer size, ulcer depth, leukocyte count, treatment, cardiovascular comorbidity, blood pressure, smoking history, septicemia, ketoacidosis, hypoalbuminemia, and upper respiratory tract infection. Chi-Square tests were performed to analyze the association of those factors with LOS. The odds ratio of each variable was evaluated using logistic regression analysis. Result. In this study, the mean of LOS was 26 days (2 – 87 days). Factors that significantly correlated with LOS were ankle-brachial index (p 0.041, OR 2.275, CI 95 % 1.025 – 5.041), ulcer size (p 0.044, OR 3.038, CI 95 % 1.032 – 9.942), smoking history (p 0.022, OR 2.434, CI 95 % 1.125 – 5.265), sepsis (p < 0.001, OR 4.240, CI 95 % 1.908 – 9.423), and ketoacidosis (p < 0.001, OR 8.611, CI 95 % 3.396 – 21.835) In multivariate analysis, the most significant factor was ketoacidosis (p < 0.001, OR 8.360, CI 95 % 3.209 – 21.780). Conclusion. Ketoacidosis is the most significant factor that prolonged hospital stays in a patient with diabetic foot ulcer. Keywords: Diabetic foot ulcer, Length of stay


2020 ◽  
Vol 14 (2) ◽  
pp. 197-205
Author(s):  
Putri Puspitasari

Pendahuluan : Diabetic Foot Ulcer (DFU) merupakan komplikasi jangka panjang yang umum ditemukan pada pasien Diabetes Mellitus (DM). Penurunan kualitas kesehatan, proses penyembuhan yang lambat, ancaman amputasi, serta ancaman kematian berdampak terhadap keadaan psikologis yang buruk bagi penderita DFU. Keadaan emosi yang mungkin timbul pada pasien dengan penyakit kronis seperti DFU adalah perasaan chronic sorrow dan Quality Of Life yang kurang baik. Tujuan dari penelitian ini adalah melihat keadaan chronic sorrow dan quality of life pada pasien dengan DFU serta secara spesifik melihat hubungan antara chronic sorrow dengan quality of life pasien dengan DFU Metode Penelitian: Penelitian ini merupakan jenis penelitian kuantitatif dengan desain analytic correlative dan rancangan penelitian menggunakan pendekatan cross sectional study. Tujuan penelitian ialah untuk menganalisis hubungan antara chronic sorrow dan kualitas hidup pada pasien dengan DFU. Sampel penelitian adalag 46 Responden. Hasil dan kesimpulan: hasil penelitian menunjukan dari 46 responden 29 (63,04 %) mengalami keadaan chronic sorrow dan diantara 46 responden 27 (58,7 %) mengalami keadaan kualitas hidup yang kurang baik. Responden yang mengalami chronic sorrow memiliki kualitas hidup yang kurang baik sebesar 78,13 % dan kualitas hidup yang baik sebesar 21,87 % dengan p= 0,000 lebih kecil dari α= 0,05, yang dapat diartikan bahwa terdapat hubungan bermakna antara keadaan chronic sorrow dan quality of life.


2020 ◽  
Vol 4 (1) ◽  
pp. 8
Author(s):  
Manik Elisa Putri

ABSTRAKLatar Belakang : Quality of Life (QoL) atau Kualitas hidup pasien dengan ulkus kakik diabetes melitus lebih buruk, daripada pasien dengan Diabetes Melitus (DM) tanpa ulkus kaki dalam populasi umum. Tujuan dari penelitian ini adalah untuk mengetahui gambaran Quality of Life (Kualitas hidup) pada pasien dengan ulkus kaki diabetes melitus (Diabetic Foot Ulcer / DFU) di Bali.Metode : Desain deskriptif dengan pendekatan cross sectional. Teknik sampel direkrut menggunakan convenience sampling yang melibatkan pasien dengan ulkus kaki diabetes melitus (Diabetic Foot Ulcer / DFU) dengan total sampel yang melibatkan 201 orang responden. yang dilakukan di ruangan department rawat jalan bedah Rumah Sakit Wangaya serta klinik perawatan luka di Bali Indonesia. Data dikumpulkan menggunakan kuesioner Diabetic Foot Ulcer Scale-Short Form (DFS-SF) dan Independent t-test digunakan untuk memahami gambaran kualitas hidup antara perempuan dan laki-laki dengan DFU. Penelitian ini sudah mendapatkan ijin etik oleh komite etik Universitas Udayana.Hasil : Karakteristik responden perempuan (n= 103; 51.2%), dan laki-laki (n= 98; 48.8%). Kualitas hidup sebagian besar memiliki kualitas hidup rendah yang buruk yaitu (<50)(n=133; 66.2%), dan kualitas hidup yang lebih baik yaitu (> 50)[n=68; 33.8%]. Skor rata-rata kualitas hidup pada pasien dengan DFU 42.4±15.5.Kesimpulan: Laki-laki dan perempuan pada pasien dengan ulkus kaki diabetes melitus menunjukkan kualitas hidup perempuan lebih rendah daripada laki-laki dengan diabetes melitus (DFU). Keluarga diharapkan tetap memotivasi dan mendukung pasien agar dapat berpartisipasi dalam aktivitas keagamaan atau kegiatan positif lainnya. Berdasarkan hasil penelitian yang telah didapat, Pasien dengan ulkus kaki diabetes melitus, baik laki-laki maupun perempuan merupakan suatu hal yang perlu kita perhatikan.  Kata Kunci : Ulkus Kakik Diabetes Mellitus, Jenis kelamin, dan Kualitas Hidup  ABSTRACTBackground: Quality of Life (QoL) or Quality of Life of patients with diabetic ulcer diabetes is worse, than patients with Diabetes Mellitus (DM) without foot ulcers in the general population. The purpose of this study was to study the description of Quality of Life (quality of life) in patients with Diabetic Foot Ulcer (DFU) in Bali. Methods: Descriptive design by discussing cross sectional. Sampling techniques were recruited using convenience sampling involving diabetic foot ulcer patients with diabetes mellitus (DFU) with a total sample involving 201 respondents. Performed in the Wangaya Hospital surgical outpatient room and wound care in Bali Indonesia. Data were collected using a Diabetic Foot Ulcer Scale-Short Form (DFS-SF) questionnaire and Independent t-test was used to collect assessments of quality of life between women and men with DFU. Udayana University Ethics Committee.Results: Characteristics of female respondents (n = 103; 51.2%), and male (n = 98; 48.8%). Quality of life mostly has a low quality of life that is poor (<50) [n = 133; 66.2%], and a better quality of life (> 50) [n = 68; 33.8%]. The mean score of quality of life was 42.4±15.5. Conclusion: Male and female patients with diabetes mellitus foot ulcers show a lower quality of life for women than men with diabetes mellitus (DFU). Families are expected to continue to motivate and support patients to participate in religious activities or other positive activities.Keywords: diabetic foot ulcer, gender, and quality of life


2019 ◽  
Vol 8 (2) ◽  
pp. 134-139
Author(s):  
Mokh Sujarwadi ◽  
Mukhammad Toha ◽  
Nurul Huda

Background: Diabetic foot ulcer is one of the chronic complications of diabetes mellitus caused by neuropathy, angiopathy and decreased endurance. The risk of amputation in patient with diabetes mellitus fifteen times greater compared to non-diabetic. Various efforts on diabetic foot wound care have been carried out but the results are still far from satisfactory. Until now, infrared and counseling effect on wound healing in diabetic foot cannot be explained.Objective: The purpose of this study was to examine the effect of infrared ray and counseling on diabetic foot ulcer healing process.Method: The research design was quasi-experimental design with posttest control group design, the population in this study were patients with grade 3 diabetic foot wounds, blood sugar 100-200 g/ dl, BMI 18.5 to 24.9, aged 35-55 years. Large sample in this study as many as 20 were divided into two groups, the control random sampling. The collection of data for the dependent variable using the observation sheet after the tenth day of treatment, which consists of the rate of growth of granulation, ankle brachial index and capillary refill time. Furthermore, the data were processed using non-parametric statistical significance level < 0.05.Result: The results showed that the infrared and counseling effect on the growth of granulation with a significance level (p = 0.0003), infrared and counseling influence ankle brachial index (p = 0.024), infrared and counseling effect on capillary and counseling effect on capillary refill time (p = 0.024).Conclusion: It can be concluded from this study that applying infrared and counseling has any impact on healing in diabetic foot ulcer, on the growth of granulation and improved blood in diabetic foot ulcers. Key words: Infrared Ray, Counseling, Foot Ulcer Healing.


Author(s):  
Dr. Sanvar Mal Kantva ◽  
Dr. Mahendra Kumar

Introduction: Diabetes is a metabolic disorder which affects not only carbohydrate but also protein and fat metabolism. Diabetes is also associated with acute as well chronic complications. Almost most of the organs, tissues and systems are affected due to long standing diabetes mellitus. Thus, adult and elderly with long standing diabetes patients often present to the clinics with multiple complications. Among all these well-known complications, diabetic foot ulcer is the most common. It affects as many as 15% of patients with diabetes mellitus during their lifetime Material and Method: The study was a hospital based cross sectional study. Present study was carried out at outpatient department of General Surgery. After their verbal informed consent after explaining them the nature of the study. Patient confidentiality was maintained. The patients diagnosed with diabetic foot ulcer were given appropriate treatment, follow up and health education. The study patients were not subjected for any kind of invasive procedure for the present study purpose. Results: 64.0% patients were having peripheral neuropathy, 73% were having >10 years of diabetes, 49% were having peripheral arterial disease, 34% patients were having diabetic Charcot joint & 26% were having uncontrolled hyperglycemia. Conclusion: Diabetes Mellitus is a lifelong disease and diabetic foot complications can be life threatening, physically incapacitating, costly to treat and result in extensive morbidity. Keywords: Diabetes, foot ulcers, neuropathy


2018 ◽  
Vol 25 (10) ◽  
pp. 1498-1502
Author(s):  
Zohaib Feroz ◽  
Abdul Raheem Memon ◽  
Nisar Ahmed Shah ◽  
Syed Zulfiquar Ali Shah

Objectives: To determine the frequency of hypomagnesemia in patients withdiabetic foot ulcer. Study Design: Cross sectional descriptive nature. Setting: Liaquat UniversityHospital Jamshoro / Hyderabad. Period: 29-09-2016 to 28-03-2017. Patients and Methods:The patients with history of diabetes mellitus (known cases) for more than 3 years durationhad diabetic foot ulcer for ≥ 02 weeks duration, of 30-60 years of age & either gender wererecruited and evaluated for serum magnesium level while the data was analyzed in SPSS 16.Results: Total 100 patients with diabetic foot ulcer were evaluated for hypomagnesaemia. Themean age ±SD of age (years), duration of diabetes (years) and foot ulcer (weeks), BMI (kg/m2),hypertension (systolic and diastolic mmHg), HBA1C and magnesium for whole population was52.86±6.87, 6.95±1.85 and 5.86±2.31, 31.92±2/43, 150.38±10.52 and 95.97±5.97, 9.96±2.73and 1.16±0.95 respectively. Out of one hundred, 55% were males and 45% were females. Thehypertension, smoking, dyslipidemia, obesity, raised HBA1C and hypomagnesemia was foundin 65%, 59%, 59%, 55%, 56% and 67%. Conclusion: Hypomagnesemia detected in subjectswith type 2 diabetes mellitus having foot ulcers.


2020 ◽  
Vol 11 (2) ◽  
pp. 2701-2706
Author(s):  
Ajoinish Kamble ◽  
Ranjit S. Ambad ◽  
Mangesh Padamwar ◽  
Anupam Kakade ◽  
Meenakshi Yeola

To Critically Assess the effect of oral vitamin D supplements on wound healing in a patient with diabetic foot ulcer and its impact on lipid metabolism. This is a single-Centre prospective randomised, control-controlled study was conducted in Department of Surgery Datta Meghe Medical College, Hingna, Nagpur, in collaboration with Datta Meghe Institute of Medical Sciences (DMIMS) Deemed to be University from June 2019 TO March 2020. A total of sixty patients were included in this study. A randomised grouping was done, group A vitamin d supplements and group B as an x-control group. In the group, A vitamin D levels were significantly increased after 12 weeks of intervention as compared to baseline while in group B, no change was seen after the intervention. There was a significant change in HbA1c level after intervention as group A vs group B. similar results were seen in total cholesterol levels after intervention in group A, and group B. Wound surface area was (29.83±15.02 vs 21.76±11.30, p=0.02) in group A and (25.06±14.02 vs 21.3±13.19, p=0.28) in group B respectively. The level of high-density lipoprotein in the group was significantly lower in level when compared to group A after 12 weeks of intervention. No significant changes were seen in the triglycerides level in group A and group B., A comparison of group A vs group B after 12 weeks of intervention, was done. It revealed that Vitamin D Glycosylated total haemoglobin cholesterol, High-density lipoprotein and Wound surface area, significantly improved. At the same time, there was no change seen in triglycerides levels in both the group.After intervention with vitamin D supplements for 12 weeks among patients with diabetic foot ulcer had a good result and beneficial effect on glucose metabolism, vitamin D levels, lipid profile and wound healing


2020 ◽  
Vol 7 (2) ◽  
pp. 88-98
Author(s):  
Niken Safitri Dyan Kusumaningrum ◽  
Afriana Dwi Saputri ◽  
Henni Kusuma ◽  
Meira Erawati

Diabetic Foot Ulcer (DFU) is one of the complications often experienced by patients with diabetes mellitus (DM). This is a serious problem that leads to disability, morbidity, and mortality among diabetic patients. However, in Indonesia, studies about DFU characteristics are very limited. This study aimed to describe DFU characteristics among patients with DM. A consecutive sampling involved patients who met inclusion criteria was performed in Tugurejo Hospital; Islamic Sultan Agung Hospital, and Dr. Moewardi Hospital. Their demographic characteristics, clinical condition, and wound appearances were noted and documented. Diabetic Foot Ulcer Assessment Scale (DFUAS) that consists of 11 characteristics was used to observe the wound features. The data were quantitatively analyzed to elucidate the result. A total of 73 patients participated in this study. It was revealed that 50.7% were females and 75.3% have been diagnosed with hyperglycemia. The average age of the respondents was 53.26 years. Observation of DFU characteristics showed that depth of wound was identified more in subcutaneous/ dermis to fatty tissue (40 patients; 54.8%) than in other layers. Moreover, our findings indicated that most of the respondents were identified at a severe level of the wound (55; 75.3%). It is concluded that DFU characteristics vary among patients with DM. Early identification and intensive surveillance are important to improve the management of DFU and to avoid lower limb amputation.


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