Association between Thyroid Function and Erythrocyte Indices in General Population from the Asir Region of Saudi Arabia: A Cross-Sectional Study

2021 ◽  
Vol 20 (1) ◽  
pp. 200-206
Author(s):  
Alqahtani Saif Aboud M

The purpose of the current investigation is to evaluate the relationship between erythrocyte indices and thyroid function in a general population from the southern region of Saudi Arabia. In a cross-sectional study conducted on 3,007 subjects examined associations among erythrocyte indices, thyroid-stimulating hormone, and free thyroxine. The average age of the population was 48.40±0.261 years, ranging from 13 years to 90 years, and the most represented age group was <50 years. Thyroid dysfunction was observed in 8.41% of the study population, and the most common thyroid dysfunction was subclinical hypothyroidism followed by clinical hyperthyroidism. Most erythrocyte indices were significantly lower in the hypothyroidism group (both primary and subclinical) in comparison to the euthyroid group stratified by gender. According to our investigation, microcytic hypochromic anemia and normocytic normochromic anemia were detected in patients with hypothyroidism. Furthermore, females with subclinical hypothyroidism had a significantly higher prevalence of anemia than male population.

2021 ◽  
Vol 59 (234) ◽  
Author(s):  
Manoranjan Shrestha ◽  
Reshmi Shrestha

Introduction: Thyroid dysfunction prevalence is high in females worldwide which increases with age. Postmenopausal and elderly women are particularly at risk of developing comorbidities and mortality related to thyroid dysfunction. We aimed to study the prevalence of thyroid dysfunction in postmenopausal women in the National Reference Laboratory of Nepal. Methods: A descriptive cross-sectional study was conducted in National Reference Laboratory from January 2019 to June 2019 including postmenopausal females, ≥49 years. The database of thyroid function test result was used for statistical analysis and proportion of thyroid dysfunction was calculated. The data was collected after approval from the institutional review committee. Statistical Package for Social Sciences version 21 was used to study descriptive data. Results: Out of a total of 160 postmenopausal females with thyroid function tests, 71 (44.4%) had thyroid dysfunction. Subclinical hypothyroidism was the frequently occurring thyroid dysfunction 51 (32%) followed by subclinical hyperthyroidism 13 (8%), hypothyroidism 3 (2%) and hyperthyroidism 3 (2%). In our study population, thyroid dysfunction peaked at 49 to 58 years of age interval 53 (33.1%) and subclinical hypothyroidism was the most frequent form 38 (23.7%). Conclusions: Subclinical hypothyroidism was the common thyroid dysfunction in postmenopausal age which peaked at 49 to 58 years of age group. Early postmenopausal females are predisposed to increased risk of comorbidities (cardiovascular disease, osteoporosis with high fracture, depression) which could be exacerbated with thyroid dysfunction; therefore awareness of thyroid dysfunction prevalence and thyroid screening for early management seems appropriate in Nepalese postmenopausal women.


Author(s):  
Ziyad Alzahrani ◽  
Syed Faisal Zaidi ◽  
Hatem Alsolami ◽  
Bader Bashrahil ◽  
Nawaf Alghamdi ◽  
...  

Background: In recent years, consumption of E-cigarettes has increased dramatically. Several studies have focused on the prevalence of E-cigarettes among specific groups of people, using it as a substitute to traditional cigarettes, or the participant knowledge regarding risks. This research was aimed on E-cigarettes’ prevalence and its association to several factors in the general population of Western Saudi Arabia.Design and Methods: Using an observational cross-sectional study, data were collected from (n=465) above 18 years old smokers during the survey at public attractions. A validated self-administered questionnaire acquired from previous studies was employed to insure the suitability for the general population of Jeddah Saudi Arabia. Sample size was calculated via Raosoft@ and adults of either gender were included in the study. Descriptive or inferential statistical analysis was performed using SPSS.Results: The preponderance of e-cigarette smokers used entertainment as the reason for smoking, with an average of (33.9%). Although one reason for e-cigarette consumption was to cease traditional smoking, results showed an average of (49.4%), which is the majority of those who attempted to cease traditional smoking via e-cigarette, did not succeed in quitting traditional smoking. This study also demonstrated that participant that believed that e-cigarette is beneficial had a higher chance to cease conventional smoking than who did not (32.1% versus 14.6%) which is significant (p<0.001).Conclusions: In conclusion, this study estimated the prevalence of e-cigarette consumption among the population of Jeddah, Saudi Arabia along with assessment of elements which help increase the overall e-cigarette consumption in Jeddah.


2021 ◽  
Author(s):  
Sahar S. Othman ◽  
Abeer Alsuwaidi ◽  
Rafal Aseel ◽  
Reema Alotaibi ◽  
Reem Bablgoom ◽  
...  

Abstract BackgroundThe 2019 Coronavirus Disease Pandemic (COVID-19) is a worldwide global epidemic. Although acceptance of COVID-19 vaccination will be a critical step in combating the pandemic, achieving high uptake will be difficult, and potentially made more difficult by social media misinformation. This study aimed to examine the association between social media use and acceptance of receiving COVID-19 vaccine among the general population in Saudi Arabia.MethodologyA cross-sectional study was conducted from June 17 to June 19, 2021 among 504 participants of the general population in Saudi Arabia. The data were collected using a three-part online questionnaire (sociodemographic characteristics, medical and vaccination history, pattern of social media use). ResultsAmong 504 participants who completed the survey, 477 participants were acceptant of the vaccine and 27 were non-accepting. A total of 335 individuals had already received the vaccine, 142 were willing to receive the vaccine and 27 were unwilling. One hundred and thirty participants denied using social media for COVID-19 news. Four factors were found to be significant in influencing vaccine acceptance in univariate analysis: having a chronic condition, believing that infertility is a side effect of the COVID-19 vaccine, being concerned about a serious side effect from the vaccine and basing the decision to be vaccinated on social media information. Two of these factors fell away on multivariate analysis: basing the decision on social media information and a belief that vaccination causes infertility, suggesting that the associations are dependent on other factors.Conclusion‏In conclusion, there was no significant independent relationship between social media usage and people's willingness to receive a COVID-19 vaccination.


2021 ◽  
Vol 9 (08) ◽  
pp. 385-391
Author(s):  
Masoud Ahmad Al-Ghamdi ◽  
◽  
Tariq Abdullah Aldugman ◽  
Alaa Rashad Hassanein ◽  
Hoda Jehad Abousada ◽  
...  

Among most Medical staff the orthopaedic complaint is very common and, in this research, we focused on the overall Prevalence of orthopaedic disorders among Medical workers, orthopaedic conditions differences between genders and educational levels. Then we overviewed the rates of orthopaedic diseases in different age groups in the general population. This study participants were Medical workers from Saudi Arabia and the results may not be applied to different sittings due to differences in facilities and work conditions.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Kejun Wu ◽  
Yu Zhou ◽  
Sujie Ke ◽  
Jingze Huang ◽  
Xuelin Gao ◽  
...  

Abstract Background Few studies have focused on the association between lifestyle and subclinical hypothyroidism (SCH). The purpose of this study was to investigate the association between lifestyle and thyroid function in SCH. Methods This study was a part of a community-based and cross-sectional study, the Epidemiological Survey of Thyroid Diseases in Fujian Province, China. A total of 159 participants with SCH (81 males and 78 females) and 159 euthyroid (87 males and 72 females) participants without any missing data were included in the analysis. General information and lifestyle information including sleep, exercise, diet and smoking habits of the participants was collected by questionnaire and Pittsburgh sleep quality index scale (PSQI) was collected. Thyroid stimulating hormone (TSH), free thyroxine (FT4), thyroid peroxidase antibody (TPOAb), thyroid globulin antibody (TgAb) and urine iodine concentration (UIC) were tested. Thyroid homeostasis parameter thyroid’ s secretory capacity (SPINA-GT), Jostel’s TSH index (TSHI), thyrotroph T4 sensitivity index (TTSI) were calculated. Logistic regression and multiple linear regression were performed to assess associations. Results Compared with euthyroid subjects, patients with SCH were more likely to have poor overall sleep quality (15.1 vs.25.8 %, P = 0.018) and l less likely to stay up late on weekdays (54.7 vs. 23.9 % P < 0.001). In SCH group, exercise was the influencing factor of TSH (β= -0.224, P = 0.004), thyroid secretory capacity (β = 0.244, P = 0.006) and thyrotropin resistance (β = 0.206, P = 0.009). Iodine excess was the influencing factor of thyroid secretory capacity (β = 0.209, P = 0.001) and pituitary thyroid stimulating function (β = 0.167, P = 0.034). Smoking was the influencing factor of pituitary thyroid stimulating function (β = 0.161, P = 0.040). Staying up late on weekends was the influencing factor of thyroid secretory capacity (β = 0.151, P = 0.047). After adjusting for possible confounders, logistic regression showed that those with poor overall sleep quality assessed by PSQI and iodine excess had an increased risk of SCH (OR 2.159, 95 %CI 1.186–3.928, P = 0.012 and OR 2.119, 95 %CI 1.008–4.456, P = 0.048, respectively). Conclusions Lifestyle including sleep, smoking, diet and exercise was closely related to thyroid function especially thyroid homeostasis in SCH.


2018 ◽  
Vol 18 (3) ◽  
pp. 350 ◽  
Author(s):  
Rawan Alanazi ◽  
Ahmed Alrahim ◽  
Sara Bayounos ◽  
Abdulrahman Al-Ghuwainem ◽  
Mohammad H. Al-Bar

Objectives: This study aimed to assess potential associations between self-reported symptoms of laryngopharyngeal reflux (LPR) and voice disorders among two undiagnosed cohorts in Saudi Arabia. Methods: This cross-sectional study was conducted from February to April 2017 in Khobar, Saudi Arabia. Validated Arabic versions of the Reflux Symptom Index (RSI) and 10-item Voice Handicap Index (VHI-10) were distributed to 400 teachers at 13 schools and 300 members of the general population attending an ear, nose and throat clinic in Khobar. Scores of >13 and >11 on the RSI and VHI-10 indicated a potential subjective diagnosis of LPR and voice disorders, respectively. Results: A total of 446 individuals took part in the study, including 260 members of the general population (response rate: 86.7%) and 186 teachers (response rate: 46.5%). The mean age was 32.5 years. In total, 62.2% complained of voice and/or reflux problems, with the remaining 37.8% not reporting/unaware of any problems in this regard. Among the teachers, 30.6% and 18.3% had positive RSI and VHI-10 scores, respectively, while 43.1% and 14.6% of the individuals from the general population had positive RSI and VHI-10 scores, respectively. Overall, VHI-10 scores were significantly associated with RSI scores (P <0.001). Conclusion: A significant association between RSI and VHI-10 scores suggests that there may be an association between LPR and voice disorders. These tools would therefore be a valuable method of monitoring patients; however, they cannot be used to confirm a diagnosis. Thus, more detailed studies are needed to confirm this association using a larger sample size.Keywords: Voice Disorders; Laryngopharyngeal Reflux; Hoarseness; Diagnostic Self Evaluation; School Teachers; Saudi Arabia.


2021 ◽  
Vol 28 (09) ◽  
pp. 1326-1330
Author(s):  
Tahir Rashid ◽  
Irfan Mirza ◽  
Abdul Rauf ◽  
Syed Hassan Mustafa ◽  
Talha Durrani ◽  
...  

Objective: Objective of this study was to determine the frequency of sub clinical hypothyroidism among chronic kidney disease patients in our population. Study Design: Descriptive Cross sectional study. Settings: Department of Nephrology, Khyber Teaching Hospital Peshawar. Period: February 2018 to September 2018. Material & Methods: A total of 145 chronic kidney disease patients were included in this study. Thyroid function tests (TFT, s) were performed in all patients along with history and clinical examination. Sub clinical hypothyroidism was defined as high TSH (normal value 0.27-4.0 µIU/ml) and normal Free T47. (0.93 – 1.70 ng/dl). Results: Our study shows that Mean age was 55 years with standard deviation ± 2.83. Eighty seven (60%) patients were male and 58(40%) patients were female. Moreover, 25% patients had subclinical hypothyroidism. Conclusion: Our study concludes that the incidence of subclinical hypothyroidism in chronic kidney disease was found to be 25% in our population.


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