Hormonal Biochemical Markers in Ectopic Pregnancy Monitoring

2018 ◽  
Vol 69 (6) ◽  
pp. 1558-1561
Author(s):  
Anca Daniela Braila ◽  
Cringu Antoniu Ionescu ◽  
Alina Calin ◽  
Anca Emanuela Musetescu ◽  
Cristian Lungulescu ◽  
...  

Ectopic pregnancy is a polymorphic disorder, with difficult early diagnosis, and in late stages it determines serious complications, targeting obstetrical and vital prognosis of the patient. A precise and early diagnosis is supported on ultrasound and dosage of the b-hCG dynamics. The presence of b-hCG, the empty uterine cavity on ultrasound tests, the detection of a periuterine tumor mass leads to the diagnosis of ectopic pregnancy. The treatment of ectopic pregnancy is a medical and surgical one. The medical treatment is preferred by most clinicians when it is possible. Our study aims to diagnose and monitor the tubal ectopic pregnancy under methotrexate treatment through biochemical marker hormone b-hCG and progesterone dosing in dynamics. Success or failure rate of the conservatively treatment with methotrexate depends on the initial b-hCG value. The purpose to spare fertility of the young women who want to procreate has led us to avoid surgery and give more weight to curative therapeutic behavior.

Author(s):  
Surbhi Lodha ◽  
Kimaya Mali

Ectopic pregnancy is defined as pregnancy outside uterine cavity. Of all ectopic pregnancy, tubal ectopic is most common. Most cases today are diagnosed early and hence timely treatment is possible. In stable patients, medical line of management with methotrexate can be used. With early diagnosis and medical line of treatment, use of injectable methotrexate is on rise. Being aware of characteristics of methotrexate like mechanism, dosage, side effects and contraindications, appropriate patient selection and watchful monitoring will help reduce methotrexate induced toxicity.


2015 ◽  
Vol 26 (7) ◽  
pp. 1971-1980 ◽  
Author(s):  
Ming-Jue Si ◽  
Shuang Gui ◽  
Qin Fan ◽  
Hong-Xiu Han ◽  
Qian-Qian Zhao ◽  
...  

Author(s):  
Jayanta K. Biswas ◽  
Vivek Tewari

Ectopic pregnancy is a condition, where the fertilized ovum implants anywhere other than normal uterine cavity. It is life threatening emergency condition and it can present in diverse ways. More than 95% of ectopic pregnancies usually occur in fallopian tube, ampulla being commonest site of tubal ectopic pregnancy. Diagnosis with location of pregnancy is usually possible by ultrasonography in 1st trimester. However, in most of the developing countries with limited resources, many women do not undergo ultrasonography and medical examination in early pregnancy, leading to late diagnosis. It may lead to life threatening presentation of ectopic pregnancy. Reported average duration of diagnosis of unruptured tubal ectopic pregnancy is usually between 5 to 9 weeks of gestation. Very rarely tubal ectopic pregnancy can remain asymptomatic and unruptured for longer than this usual period of gestation. The reported case is a rare case of viable, unruptured tubal ampullary ectopic pregnancy of 14 weeks of gestational age.


2020 ◽  
Vol 1 (1) ◽  
pp. 60-63
Author(s):  
Palwasha Gul ◽  
Khanda Gul ◽  
Pari Gul ◽  
Tanzila Parveen

Background: An ectopic pregnancy (EP) is a type of conception in which, the fertilized egg is lodged outside the uterine cavity. Twin ectopic pregnancies are a rarity, and the reported cases of twin tubal pregnancies are a handful to date.Case Report: We report a case of a 35 years old patient who presented to the emergency with the complaint of lower abdominal pain and intermittent vaginal discharge. She was diagnosed with twin tubal alive gestation, underwent exploratory laparotomy and right salpingectomy.Conclusion: Ectopic pregnancy can occur even in the absence of known risk factors. Its incidence is on the rise. It is a leading cause of first-trimester maternal deaths and can be easily diagnosed with Beta HCG levels and transvaginal ultrasound.


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