scholarly journals HARNESS FITTINGS OF 7th—6th CENTURIES BC IN THE TRANSCAUCASIA AND THE NEAR EAST

2018 ◽  
Vol 27 (2) ◽  
pp. 35-50
Author(s):  
S. V. Makhortykh
Keyword(s):  
Near East ◽  
Northern Caucasus ◽  
Forest Steppe ◽  
The South ◽  
South Caucasus ◽  
Different Types ◽  
Main Period ◽  
Group 2 ◽  
Group 1

The article is devoted to the analysis of different types of metal and bone harness fittings of VII—VI centuries BC which were found in the South Caucasus and the Near East. Among those fittings, which are constituted about 50 artifacts, two major groups could be distinguished: plain fittings of various geometric shapes and fittings with zoomorphic decorations. The latter group dominates and constitutes about 80 % of the total number of findings. The major regions of distribution of these horse harness attachments are Armenia and Turkey. The cylindrical harness fittings of the first type from the group 1 were the most widespread among the geometrical samples (8 items), while among the zoomorphic ones — claw-shaped, or beak-shaped objects of type 1 from the group 2 (19 items). It should be noted that the majority of the analyzed finds were found not in burial monuments, as in the Northern Caucasus and in the Ukrainian forest-steppe, but at settlements. The emergence of the tradition of manufacturing, as well as the widespread using of various types of harness fittings, and primarily the zoomorphic ones, to the South of the main Caucasian ridge, was the result of the staying and activity on this territory of the Scythians of the South of Eastern Europe. The main period of existence of strap-dividers in Transcaucasia and the Near East was the second half of the VII — the first half of the VI centuries BC.

scholarly journals Percutaneous posteroanterior screw fixation for Haraguchi type 1 posterior malleolar fracture in tri-malleolar fracture: Operative technique and randomized clinical results

2021 ◽  
Vol 29 (1) ◽  
pp. 230949902199799
Author(s):  
Tianming Yu ◽  
Jichong Ying ◽  
Jianlei Liu ◽  
Dichao Huang ◽  
Hailin Yan ◽  
...  
Keyword(s):  
Screw Fixation ◽  
Malleolar Fracture ◽  
Malleolar Fractures ◽  
Posterior Malleolar Fracture ◽  
Post Traumatic ◽  
Group 2 ◽  
Traumatic Arthritis ◽  
Group 1

Purpose: The study described a novel surgical treatment of Haraguchi type 1 posterior malleolar fracture in tri-malleolar fracture and patient outcomes at intermediate period follow-up. Methods: All patients from January 2015 to December 2017 with tri-malleolar fracture of which posterior malleolar fractures were Haraguchi type 1, were surgically treated in this prospective study. Lateral and medial malleolar fractures were managed by open reduction and internal fixation through dual incision approaches. 36 cases of Haraguchi type 1 posterior malleolar fractures were randomly performed by percutaneous posteroanterior screw fixation with the aid of medial exposure (group 1). And 40 cases were performed by percutaneous anteroposterior screw fixation (group 2). Clinical outcomes, radiographic outcomes and patient-reported outcomes were recorded. Results: Seventy-six patients with mean follow-up of 30 months were included. There were no significant differences in the mean operation time (81.0 ± 11.3 vs. 77.2 ± 12.4), ankle function at different periods of follow-up, range of motions and visual analog scale (VAS) at 24 months between the two groups ( p > 0.05). However, the rate of severe post-traumatic arthritis (Grade 2 and 3) and the rate of step-off rather than gap in radiological evaluation were lower in group 1 than that in group 2 ( p < 0.05). Conclusion: Using our surgical technique, more patients had good outcome with a lower rate of severe post-traumatic arthritis, compared with the group of percutaneous anteroposterior screw fixation. Percutaneous posteroanterior screw fixation can be a convenient and reliable alternative in treating Haraguchi type 1 posterior malleolar fracture.

scholarly journals Type 1 FSHD with 6–10 Repeated Units: Factors Underlying Severity in Index Cases and Disease Penetrance in Their Relatives Attention

2020 ◽  
Vol 21 (6) ◽  
pp. 2221
Author(s):  
Emmanuelle Salort-Campana ◽  
Farzad Fatehi ◽  
Sadia Beloribi-Djefaflia ◽  
Stéphane Roche ◽  
Karine Nguyen ◽  
...  
Keyword(s):  
Disease Severity ◽  
Facioscapulohumeral Muscular Dystrophy ◽  
Clinical Severity ◽  
Cross Sectional ◽  
Repeat Array ◽  
D4z4 Repeat ◽  
Severity Scores ◽  
Group 2 ◽  
Group 1

Molecular defects in type 1 facioscapulohumeral muscular dystrophy (FSHD) are caused by a heterozygous contraction of the D4Z4 repeat array from 1 to 10 repeat units (RUs) on 4q35. This study compared (1) the phenotype and severity of FSHD1 between patients carrying 6–8 vs. 9–10 RUs, (2) the amount of methylation in different D4Z4 regions between patients with FSHD1 with different clinical severity scores (CSS). This cross-sectional multicenter study was conducted to measure functional scales and for genetic analysis. Patients were classified into two categories according to RUs: Group 1, 6–8; Group 2, 9–10. Methylation analysis was performed in 27 patients. A total of 99 carriers of a contracted D4Z4 array were examined. No significant correlations between RUs and CSS (r = 0.04, p = 0.73) and any of the clinical outcome scales were observed between the two groups. Hypomethylation was significantly more pronounced in patients with high CSS (>3.5) than those with low CSS (<1.5) (in DR1 and 5P), indicating that the extent of hypomethylation might modulate disease severity. In Group 1, the disease severity is not strongly correlated with the allele size and is mostly correlated with the methylation of D4Z4 regions.

Effect of Unilateral Accessory Navicular Bone on Radiologic Parameters of Foot

2020 ◽  
pp. 107110072096482
Author(s):  
Mustafa Kara ◽  
Serkan Bayram
Keyword(s):  
Navicular Bone ◽  
Level Of Evidence ◽  
First Metatarsal ◽  
Metatarsal Angle ◽  
Asymptomatic Patients ◽  
Accessory Navicular ◽  
The Mean ◽  
Group 2 ◽  
Group 1

Background: This study aimed to compare the radiologic parameters of both feet in patients with unilateral accessory navicular bone (ANB) and evaluate the differences from one another. Methods: Forty-one patients with unilateral ANB volunteered to participate in this study from August 2019 to January 2020. Patient data, including age, sex, body mass index (BMI), type of ANB, and presence of symptoms were obtained. Group 1 comprised 23 patients with asymptomatic unilateral ANB, and group 2 comprised 18 patients with symptomatic unilateral ANB. Seven radiologic parameters were evaluated assessing hindfoot, midfoot, and forefoot alignment—calcaneal pitch angle, talocalcaneal angle, tibiocalcaneal angle, naviculocuboid overlap (NCO), talonavicular coverage angle (TNCA), anteroposterior talo–first metatarsal angle, and lateral talo–first metatarsal angle. Results: The mean age of patients was 40.1 years in group 1 and 42.6 years in group 2. Mean BMI was 25.2 in group 1 and 26.6 in group 2. No significant differences were noted in the radiologic parameters between the ANB and contralateral sides in all patients. The radiologic parameters of both feet in symptomatic and asymptomatic patients were not significantly different. No significant differences were noted between the affected sides of type 1 and 2 ANB and contralateral sides in terms of the radiologic parameters. BMI was significantly correlated with NCO and TNCA. Conclusion: This study demonstrated that the presence of an accessory navicular bone did not affect radiologic parameters of the foot. Radiologic parameters of both feet in symptomatic patients were not significantly different. Level of Evidence: Level III, diagnostic, comparative study.

THE EFFECT OF CONTINUOUS SUBCUTANEOUS INSULIN INFUSION TREATMENT, INSULIN ANALOG, AND HUMAN INSULIN OF CHILDREN WITH DIABETES

2015 ◽  
Vol 3 ◽  
pp. 432-436
Author(s):  
Elina Petkova ◽  
Valentina Petkova ◽  
Guenka Petrova ◽  
Maya Konstantinova
Keyword(s):  
Type 1 Diabetes ◽  
Cost Effectiveness ◽  
Human Insulin ◽  
Continuous Subcutaneous Insulin Infusion ◽  
Insulin Infusion ◽  
Subcutaneous Insulin ◽  
Group 3 ◽  
Group 2 ◽  
Group 1

The aim of this study is to evaluate the cost-effectiveness of  continuous subcutaneous insulin infusion (CSII) to multiple daily insulin injection (MDI) either with analogues or with human insulin, based on the achieved therapeutic results such as changes in glycated hemoglobin level (HbA1c) in the various therapies. The study was performed with children with type-1 diabetes in Bulgaria. The objective of this study was to serve for the Bulgarian National Health Fund (NHIF).Methods: A combined retrospective and prospective study was performed at the Endocrinology diabetes and genetic diseases clinic.51 children with type-1 diabetes were observed for 7 months diveded into three group: Group 1- on continuous subcutaneous insulin infusion (CSII); Group 2- on multiple daily insulin analogues injections (MDI) and Group 3 – on human insulin (HI).Patient demographic data, age, sex, weight, duration of disease, HbA1c – values before the start of the study and after the end of the observation and type of treatment (CSII; MDI or HI) were observed. Cost-effectiveness, sensitivity and statistical analyses are applied to studied long-term therapeutic results.Results: The three groups of observed children do not differ statistically in age and gender. Most of the participants in Group 1 and Group 2 have suffered from diabetes from 5,6 years. The duration of diabetes was lower in the group of human insulin. All studied children are treated. By all of them the results of the treatment improved, but in the Group 1 the improvement of HbA1c is the highest. The average improvement of HbA1c in the Group 1 after the CSII introduction is 1.85, while after the application of analogue insulin is 0,59 and 0,28 respectively in the Group 3 after the treatment on human insulin.The cost of insulin pump, consumables- infusion set and insulin reservoir, blood glucose monitoring system, strips, needles and insulin cost was calculated.The total cost ot the treatment of diabetes with insulin pump for 7 months is 2358,85Euro; 856,98 Euro in the Group 2 on MDI and 744,24 Euro for 7 months in the Group 3 on human insulin.The differences in costs and therapeutic results permit to conduct cost- effectiveness analysis by comparing of the three alternatives.Our study shows that the CSII pumps allows better diabetes control compared to the treatment with analogue insulin and human insulin. Insulin pumps are also cost- effectiveness alternative for children with type 1 diabetes.

scholarly journals Differences in Menin Expression in Pituitary Adenomas in Multiple Endocrine Neoplasia Type 1, Its Phenocopies and Sporadic Acromegaly

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. A535-A536
Author(s):  
Diana A Dimitrova ◽  
Elizaveta O Mamedova ◽  
Anastasia M Lapshina ◽  
Vilen N Azizyan ◽  
Andrey Y Grigoriev ◽  
...  
Keyword(s):  
Pituitary Adenomas ◽  
Multiple Endocrine Neoplasia ◽  
Multiple Endocrine Neoplasia Type ◽  
Cytoplasmic Expression ◽  
Men 1 ◽  
Endocrine Neoplasia ◽  
Group 3 ◽  
Group 2 ◽  
Group 1

Abstract Introduction: Multiple endocrine neoplasia type 1 syndrome (MEN 1) is caused by mutations in MEN1 gene, encoding menin protein. A combination of pituitary adenomas (PA) and primary hyperparathyroidism (PHPT) in patients without MEN1 mutations is defined as MEN 1 phenocopy. The aim of the study is to find if there are any differences in menin expression in PA of patients with genetically confirmed MEN 1, MEN 1 phenocopies and sporadic acromegaly. Materials and Methods: Formalin-fixed paraffin-embedded PA tissues were obtained from 9 genetically confirmed MEN 1 patients (group 1), 12 patients with MEN 1 phenocopies (a combination of PA and PHPT) (group 2) and 14 patients with sporadic acromegaly (group 3). The integrity of the tissues was tested by immunohistochemistry (IHC) using antibodies against the nuclear protein Pit-1. MEN1 mutations were confirmed or excluded by Sanger sequencing or by NGS (NextSeq550, Illumina, USA). Expression of menin was assessed using IHC (Anti-Menin antibody — ChIP Grade, Abcam, UK). Results: The distribution of PA by the type of secretion in group 1 was: 3 — ACTH-secreting, 2 — PRL-secreting, 2 — GH+PRL, 1 — TSH+PRL, 1 — ACTH+PRL, 1 — silent gonadotroph adenoma. All 12 PA from group 2 were GH-secreting. All 14 PA in group 3 were GH-secreting without mixed secretion. The median age at the moment of transsphenoidal surgery in group 1 was 35 years [27; 47], in group 2 — 59 years [56; 65], in group 3 — 56 years [53; 62]. There were 2 men and 7 women in group 1; 2 men and 10 women in group 2; 4 men and 10 women in group 3. In group 1 patients did not receive somatostation analogues (SSA), 7 patients received cabergoline. In group 2 seven patients received SSA, in group 3 — 4 patients received SSA, 2 patients received cabergoline. The results of menin staining were (negative staining/positive cytoplasmic staining/positive nuclear staining): group 1 — 4/4/0; group 2 — 0/11/1; group 3 — 1/7/6. Phenocopy group showed significantly more cytoplasmic expression of menin than in MEN 1 group (p&lt;0.008). MEN 1 group also differed from sporadic acromegaly group by nuclear expression of menin (p&lt;0.015). No statistical significance between sporadic and phenocopy groups was found (p=0.07). Although there were no differences among these groups, the group 2 showed weak nuclear expression only in one case, while in group 3 the menin staining was present both in the nucleus and cytoplasm in equal proportions. Conclusion: Menin expression is generally preserved in PA in MEN 1 phenocopies and sporadic acromegaly, though with different pattern of nuclear and cytoplasmic expression, while its expression varies in PA in MEN 1. These findings suggest that pathogenesis of PA in MEN 1 phenocopies and sporadic acromegaly may have similarities. The mechanisms of co-occurrence of PA and PHPT in MEN 1 phenocopies are poorly understood and epigenetic modifications downstream menin interacting pathways could play a role.

scholarly journals Impact of glycemic variability and the fear of hypoglycemia on type 1 diabetes control

2020 ◽  
Vol 4 (6) ◽  
pp. 324-328
Author(s):  
A.R. Volkova ◽  
◽  
M.E. Chernaya ◽  
V.S. Mozgunova ◽  
M.B. Durdyeva ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Glycemic Variability ◽  
Diabetes Control ◽  
Target Level ◽  
Fear Of Hypoglycemia ◽  
Group 2 ◽  
Hba1c Target ◽  
Hba1c Levels ◽  
Group 1

Background: currently, the level of HbA1c does not necessarily allow for the understanding of glycemic control. Considering this, glycemic variability (GV) is extensively studied in recent years. Psychological component has a significant impact on GV as the fear of hypoglycemia (FOH) and its consequences can reduce the motivation for achieving target glycemia and HbA1c as well as adherence to treatment.Aim: to assess GV in patients with type 1 diabetes with the elevated and target levels of HbA1c and to analyze the effect of FOH on diabetes control.Patients and Methods: 78 patients with type 1 diabetes who received insulin therapy (multiple daily injections or continuous subcutaneous insulin infusion) were enrolled. All patients were divided into two groups based on HbA1c levels, i.e., group 1 (patients who achieved individual HbA1c target level, n=13) and group 2 (patients who did not achieve individual HbA1c target level, n=65). HbA1c levels and GV were measured in all patients using iPRO™2 Professional CGM system (Medtronic, Ireland). In addition, FOH was evaluated using the Hypoglycemia Fear Survey II (HFS-II).Results: in group 1, time in-range was significantly higher (p=0.013) while daily GV was significantly lower (p=0.023) than in group 2. HbA1c levels, the rate of severe hypoglycemia, and diabetes duration were lower among the patients with lower levels of FOH.Conclusion: studying GV can provide better understanding of diabetes control in patients with any HbA1c level. Optimized treatment strategy using HFS-II can attenuate the effects of frequent hypoglycemia on GV and HbA1c levels and improve treatment efficacy.KEYWORDS: glycemic variability, glycated hemoglobin, diabetes, continuous glucose monitoring, hypoglycemia.FOR CITATION: Volkova A.R., Chernaya M.E., Mozgunova V.S. et al. Impact of glycemic variability and the fear of hypoglycemia on type 1 diabetes control. Russian Medical Inquiry. 2020;4(6):324–328. DOI: 10.32364/2587-6821-2020-4-6-324-328.

scholarly journals Evolution and Biological Characterization of Human Immunodeficiency Virus Type 1 Subtype E gp120 V3 Sequences following Horizontal and Vertical Virus Transmission in a Single Family

1999 ◽  
Vol 73 (5) ◽  
pp. 3551-3559 ◽  
Author(s):  
Hironori Sato ◽  
Teiichiro Shiino ◽  
Noriko Kodaka ◽  
Kiyomi Taniguchi ◽  
Yasuhiro Tomita ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Positive Selection ◽  
Human Immunodeficiency Virus Type ◽  
Virus Type ◽  
Single Family ◽  
Immunodeficiency Virus ◽  
Group 2 ◽  
Hiv 1 ◽  
Group 1

ABSTRACT It has been suggested that immune-pressure-mediated positive selection operates to maintain the antigenic polymorphism on the third variable (V3) loop of the gp120 of human immunodeficiency virus type 1 (HIV-1). Here we present evidence, on the basis of sequencing 147 independently cloned env C2/V3 segments from a single family (father, mother, and their child), that the intensity of positive selection is related to the V3 lineage. Phylogenetic analysis and amino acid comparison of env C2/V3 and gagp17/24 regions indicated that a single HIV-1 subtype E source had infected the family. The analyses of unique env C2/V3 clones revealed that two V3 lineage groups had evolved in the parents. Group 1 was maintained with low variation in all three family members regardless of the clinical state or the length of infection, whereas group 2 was only present in symptomatic individuals and was more positively charged and diverse than group 1. Only virus isolates carrying the group 2 V3 sequences infected and induced syncytia in MT2 cells, a transformed CD4+-T-cell line. A statistically significant excess of nonsynonymous substitutions versus synonymous substitutions was demonstrated only for the group 2 V3 region. The data suggest that HIV-1 variants, possessing the more homogeneous group 1 V3 element and exhibiting the non-syncytium-inducing phenotype, persist in infected individuals independent of clinical status and appear to be more resistant to positive selection pressure.

scholarly journals Optical Coherence Tomography Angiography (OCTA) information content in the diagnosis of type 1 choroidal neovascularization combined with pigment epithelium detachment

2021 ◽  
Vol 14 (1) ◽  
pp. 42-46
Author(s):  
V. V. Neroev ◽  
M. V. Ryabina ◽  
A. P. Sarygina
Keyword(s):  
Choroidal Neovascularization ◽  
High Reliability ◽  
Pigment Epithelium ◽  
Antiangiogenic Therapy ◽  
Angiogenesis Inhibitors ◽  
Age Related Macular Degeneration ◽  
Pigment Epithelium Detachment ◽  
Group 2 ◽  
Group 1

Purpose of the study is to determine the reliability of OCT angiography in the diagnosis of type 1 choroidal neovascularization (CNV) in wet age-related macular degeneration depending on the height of pigment epithelium detachment (PED).Material and methods. The study included 82 patients (114 eyes) with confirmed type 1 CNV, who were examined using spectral OCT and OCTA. The patients were divided into two groups depending on PED height: group 1 consisted of 69 eyes with PED height less than 300 μm, while group 2 (45 eyes) had PED height of more than 300 μm. A separate comparative analysis of the visualization of pathological vessels was made in a group of untreated patients (56 eyes) and a group of patients (58 eyes) treated with angiogenesis inhibitors.Results. In group 1 with a PED height less than 300 μm (167.0 ± 60.4 μm) OCTA detected blood flow along abnormal vessels in 100 % of cases. In group 2 with a PED height above 300 μm (484.7 ± 131.9 μm) CNV vessels were visualized in 24.4 % of eyes. The PED height of patients after intravitreal injections of angiogenesis inhibitors (IVI IA) ranged from 38 to 683 μm (221 ± 133 μm). According to OCTA visualization of type 1 CNV vasculature was noted in 55 eyes (94.8 %). In patients who received no antiangiogenic therapy, with a PED height 59 - 800 μm (238 ± 149 μm) CNV was visualized in 41 % of cases (23 eyes).Conclusion. OCTA showed high reliability in the diagnosis of type 1 CNV with low PED. This method was significantly less informative when the height of the neovascular PED exceeded 300 μm, with the exception of PED after IVI IA.

scholarly journals Analysis of indicators of daily blood pressure profile in patients wi th type 1 diabetes, depending on the course of the disease

2018 ◽  
Vol 23 (4) ◽  
pp. 301-308
Author(s):  
N.O. Pertseva ◽  
K.I. Moshenets
Keyword(s):  
Blood Pressure ◽  
Type 1 Diabetes ◽  
Pressure Profile ◽  
Healthy Controls ◽  
Area Index ◽  
Time Index ◽  
Blood Pressure Profile ◽  
Group 2 ◽  
Group 1

The aim: to study the features of daily profile and circadian rhythm of blood pressure (BP) in groups of patients with type 1 diabetes mellitus (T1DM), depending on glycemic control. Materials and methods: 63 patients with T1DM, age: 18-45 years without hypertension were examined. Patients were divided into groups: Group 1 — HbA1c≤7.0% (n=21), Group 2 — HbA1c>7.0% (n=42). 10 sex- and agematched healthy controls were included. Results: Patients with T1DM had a significantly higher pulsatile blood pressure (PBP) per night, higher daily systolic blood pressure (SBP) variability, compared with healthy controls, and significantly higher daily SBP area index (SPAI24), daily SBP time index (SPTI24), daily diastolic blood pressure (DBP) area index (DPAI24), daily DBP time index (DPTI24). The double product (DP) was higher in patients with T1DM in the daytime and within 24 hours compared to control (p=0.002) and (p=0.001) respectively. Pathological profiles of daily blood pressure were found. In group 1, according to the dipping in SBP 28.57% of patients were non-dippers, 4.76% were extreme dippers. In group 2, the non-dipper profile had 33.33%, the reverse dipper had 2.38%, and extreme dipper had 11.90% of patients. According to the dipping in DBP: in group 1 33.33% were non-dippers, and 9.53% were extreme dippers. In group 2 non-dippers — 19.04%, extreme dippers — 2.38%, extreme dippers — 38.10%. HbA1c directly correlates with: (DPAI24) (ρ=0,301; р=0,014), DPAI night (ρ=0,292; р=0,010), DPTI24 (ρ=0.292; p=0.012), DPTI night (ρ=0.268; p=0.018). Conclusions. The daily blood pressure profile in patients with T1DM without arterial hypertension is characterized by insufficient decrease in BP at night, an increase in the average daily DBP, PBP, as well as DPAI24, DPTI24, DP and the variability of the average daily SBP. Poor glucose control led to led to an increase in hemodynamic load. It is the risk factor cardiovascular complications in patients with T1DM.

scholarly journals Importance of food plants in the prevention and treatment of diabetes in Cameroon

2019 ◽  
Vol 2 (2) ◽  
pp. 11
Author(s):  
Nole Tsabang ◽  
Lionel W. ◽  
Clément G. Yedjou ◽  
Paul B. Tchounwou
Keyword(s):  
Herbal Medicines ◽  
Food Plants ◽  
Diabetic Patients ◽  
Self Medication ◽  
Prevention And Treatment ◽  
Onset Of Diabetes ◽  
Group 2 ◽  
Group 1

Background: Diabetes is a metabolic pathology that affects the human body’s capacity to produce and use insulin. Type 1 (insulin-dependent) diabetes accounts for 5-10 % of diabetic patients. In Type 2 diabetes the insulin produced by the pancreatic islets is not properly used by cells leading to insulin resistance. Gestational diabetes sometimes occurs in pregnant women and affects about 18 % of all pregnancies. Diabetes is one of the most important multifactorial, metabolic and chronic diseases, with fatal complications. According to the International Diabetes Federation’s estimations in 2015, 415 million people had diabetes. By 2040 this will increase to 642 million. Although many ethnopharmacological surveys have been carried out in several parts of the world, no ethnomedical and ethnopharmacological surveys have been done to identify plants used for the prevention and treatment of diabetes.Objective: This study aimed to collect and document information on food plants’ remedies consumed for preventing and treating diabetes in Cameroon.Methods: Ethnomedical and ethnopharmacological thorough preparation was conducted nearby 1131 interviewers from 58 tribes, in a random distribution. Diabetic patients recorded among the 1,131 people who signed the informed consent and allowed us to evaluate the effectiveness of 10 food plants that they usually used in self-medication. They were divided into two groups: Group 1 was comprised of 42 diabetic patients who regularly consume certain food plants, and Group 2 included 58 patients who were town dwellers and did not regularly eat the identified food plants. Results: It was discovered that the times of onset of diabetes in patients were about 70 years and 45 years in Group 1 and Group 2, respectively. Hence, it was demonstrated that the onset of diabetes was linked to consumption of food plants which contributed to the prevention and/or the delay in its clinical manifestations.Conclusion: The results of this study provide a scientific basis for the use of herbal medicines in the management of diabetes. However further investigations and/or clinical trials involving a large number of both type 1 and type 2 diabetics are needed to confirm the therapeutic action of many food plants against diabetes.Keywords: Cameroon, food plants, diabetes, prevention and treatment

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