scholarly journals Effect of Community Characteristics and Diseases due to Metabolic Disorders on Heart Disease in Indonesia

2022 ◽  
Vol 22 (1) ◽  
2021 ◽  
Vol 10 (4) ◽  
pp. 29-38
Author(s):  
N. A. Kuzminykh ◽  
L. V. Shcherbakova ◽  
V. S. Shramko ◽  
D. V. Denisova ◽  
Yu. I. Ragino

Aim. To study the associations of electrophysiological signs of metabolic disorders with lipid and non-lipid risk factors in the urban 25–44-year-old population.Methods. A population survey (random sample) of Novosibirsk residents aged 25–44 years (656 men, 783 women) was conducted. The concentrations of total cholesterol, low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol, and triglycerides were determined. Systolic / diastolic blood pressure, body mass index, presence of arterial hypertension, and smoking status were evaluated. The following electrocardiographic markers of metabolic disturbances were analyzed: baseline non-ischemic ST elevation depression >0.5 mm, baseline ST elevation >0.5 mm, and T-wave changes (flattening, amplitude reduction, inversion).Results. ST segment depression was detected in 4.2% of subjects (5.8% women, 2.4% men (p = 0.001)). ST segment elevation was detected in 28.5% of subjects (17.5% women, 41.6% men (p<0.001)). T-wave changes were detected in 18.9% of subjects (14.2% women, 24.5% men (p<0.001)). It was noted that men with elevated LDL-C levels and hypertension were more likely to have ST segment depression (1.4 and 1.9 times, respectively) than men without these abnormalities. In the general population, people with elevated LDL-C levels were 1.2 times more likely to have ST segment depression. Among men with ST segment elevation the concentration of LDL-C in the blood was 1.06 times higher than in men without ST segment elevation. People with a higher body mass index were 1.15 and 1.3 times more likely to have a T-wave change (in the general and female population, respectively). In the general population with T-wave changes, waist circumference and systolic blood pressure level were 1.02 and 1.02 times higher, respectively.Conclusion. ST segment elevation and depression, and T-wave changes are associated with lipid and non-lipid risk factors for ischemic heart disease. The data obtained indicate a potentiating effect of metabolic disorders in the body on the development of risk factors for ischemic heart disease and metabolic cardiomyopathy.


2019 ◽  
Vol 1 (8) ◽  
pp. 14-20
Author(s):  
O. Ya. Chaykovskaya ◽  
G. V. Ryabykina ◽  
I. L. Kozlovskaya ◽  
A. V. Sobolev ◽  
E. Sh. Kozhemyakina ◽  
...  

Objective: to evaluate the diagnostic significance of the electrocardiographic (ECG) criteria for left ventricular hypertrophy (LVH) in 12 leads in patients with essential arterial hypertension (AH) and in AH in combination with ischemic heart disease (IHD) compared with echocardiography (EchoCG) data. Materials and methods: ECG and EchoCG were carried out in 165 patients with AH (n = 139) and AH with concommitant IHD (n=26). Results: EchoCG signs of LVH ("EchoCG +") were detected in 72 (51,7%) patients with AH and in 12 (46,1 %) patients in AH + IHD. In the EchoCG + group the electrocardiographic signs of LVH (Sokolov-Lyon index, Cornell product, Cornell index) were determined in 37 (30,5 %) hypertensive patients and in no case in the AH + IHD group. In the "EchoCG-" group, electrocardiographic signs of LVH were determined in 8 hypertensive patients and two in the AH + CHD group. The use of additional voltage criteria for LVH in the frontal plane leads (RI > 15 mm, R I + S III > 25 mm, R aVL > 12 mm) increased the detection of LVH from 30,5 % (n=22) to 51,3 % (n=37). The false negative ECG diagnosis of LVH was influenced by: positional features, interventricular conduction defect, metabolic disorders and high index body mass. Conclusion: The Sokolov-Lyon index, the Cornell index, the Cornell product have low sensitivity in the diagnosis of LVH (30,5 %). Adding the frontal plane leads voltage criteria for LVH may contribute to increase in electocardiographic LVH detection (51,3 %). The decrease in the sensitivity of the ECG criteria for LVH is mainly caused by the positional features of the heart, interventricular conduction defect, metabolic disorders and high index body mass.


1988 ◽  
Vol 9 (8) ◽  
pp. 258-266
Author(s):  
Martin H. Lees ◽  
Douglas H. King

The neonate with circulatory failure or cardiogenic shock is a formidable challenge. However, with an organized treatment plan and a well-orchestrated team, these infants can be effectively managed. Once the infant has been stabilized, and septic and hypovolemic shock have been excluded, attention should be directed to the four most likely causes of cardiogenic shock: structural heart disease with left heart obstruction, cardiac muscle disorders, cardiac dysrhythmias, and cardiac metabolic disorders.


2015 ◽  
Vol 8 (1) ◽  
pp. 113-132 ◽  
Author(s):  
Trisha Petitte ◽  
Jennifer Mallow ◽  
Emily Barnes ◽  
Ashley Petrone ◽  
Taura Barr ◽  
...  

Loneliness is a prevalent and global problem for adult populations and has been linked to multiple chronic conditions in quantitative studies. This paper presents a systematic review of quantitative studies that examined the links between loneliness and common chronic conditions including: heart disease, hypertension, stroke, lung disease, and metabolic disorders. A comprehensive literature search process guided by the PRISMA statement led to the inclusion of 33 articles that measure loneliness in chronic illness populations. Loneliness is a significant biopsychosocial stressor that is prevalent in adults with heart disease, hypertension, stroke, and lung disease. The relationships among loneliness, obesity, and metabolic disorders are understudied but current research indicates that loneliness is associated with obesity and with psychological stress in obese persons. Limited interventions have demonstrated long-term effectiveness for reducing loneliness in adults with these same chronic conditions. Future longitudinal randomized trials that enhance knowledge of how diminishing loneliness can lead to improved health outcomes in persons with common chronic conditions would continue to build evidence to support the translation of findings to recommendations for clinical care.


2019 ◽  
Vol 68 (3) ◽  
pp. 81-88
Author(s):  
Maria A. Shalina

This paper presents the current literature data on the pathogenesis of metabolic disorders in menopause. The association of metabolic syndrome with a high risk of coronary heart disease, hypertension, diabetes, and insulin resistance is of great medical and social importance. It emphasizes the need for early diagnosis of metabolic syndrome in older women and optimization of therapeutic and preventive measures. The article highlights the role of pathogenetic, multi-component therapy, including menopausal hormone one, in the treatment of metabolic disorders in menopause.


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