scholarly journals Genicunolide A, B and C: three new triterpenoids from Euphorbia geniculata

2015 ◽  
Vol 11 ◽  
pp. 2707-2712 ◽  
Author(s):  
Alia Farozi ◽  
Javid Ahmad Banday ◽  
Shakeel Ahmad Shah
Keyword(s):  
Chemical Methods ◽  
Aerial Parts ◽  
Euphorbia Geniculata

Three new triterpenoids, designated as genicunolide A (1), B (2) and C (3), along with friedelin (4) and friedelinol (5), were isolated from the aerial parts of Euphorbia geniculata. They were characterized as 1β-acetoxy-3β-hydroxy-11α,12α-oxidotaraxer-14-ene, 1β,3β-diacetoxy-21α-hydroxy-11α,12α-oxidotaraxer-14-ene and 3β,9α,20α-trihydroxy-Ψ-taraxast-5-ene, respectively, by spectral and chemical methods.

scholarly journals New Diterpenes from Azorella spinosa

2014 ◽  
Vol 9 (1) ◽  
pp. 1934578X1400900 ◽  
Author(s):  
Luis Astudillo ◽  
Margarita Gutiérrez ◽  
Luisa Quesada ◽  
Aurelio San-Martín ◽  
Luis Espinoza ◽  
...  
Keyword(s):  
Ursolic Acid ◽  
Significant Activity ◽  
Chemical Methods ◽  
Enzymatic Assays ◽  
Aerial Parts ◽  
Basic Hydrolysis ◽  
Hydrolysis Of

Two new diterpenes,2-acetoxy-13-hydroxy-mulin-11-ene and 2-acetoxy-mulin-11, 13-diene, have been isolated from the aerial parts of Azorella spinosa and their structures determined by spectroscopic and conventional chemical methods. Furthermore, 2, 13-dihydroxy-mulin-11-ene was obtained using a basic hydrolysis of the first compound. Two diterpenes reported for other Azorella species have also been found, namely mulinolic acid and 13β-hydroxyazorellane, as well as the triterpene lactone of ursolic acid, quercetin, and 7-hydroxycoumarin. The compounds were evaluated using antibacterial, antioxidant and enzymatic assays; no significant activity was detected.

scholarly journals New Iridoid from Aerial Parts of Mussaenda Roxburghii

2012 ◽  
Vol 7 (1) ◽  
pp. 1934578X1200700 ◽  
Author(s):  
Utpal Chandra De ◽  
Ranjit Ghosh ◽  
Sanjib Chowdhury ◽  
Biswanath Dinda
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
2D Nmr ◽  
Dilution Method ◽  
Chemical Methods ◽  
Aerial Parts ◽  
Broth Dilution

A new iridoid, shanzhiol (1), was isolated from the aerial parts of Mussaenda roxburghii. The structure was established by spectroscopic (including 2D NMR) and chemical methods. Shanzhiol (1) showed mild antibacterial activity against both Staphylococcus aureus and Escherichia coli with a MIC of 100 μg/mL by the broth dilution method.

The Minor Iridoid Glucosides of Barleria lupulina: Isolation, Crystal Structure and Plant Growth-Inhibiting Properties of 6-O-Acetylshanzhiside Methyl Ester

1987 ◽  
Vol 40 (5) ◽  
pp. 785 ◽  
Author(s):  
LT Byrne ◽  
JM Sasse ◽  
BW Skelton ◽  
A Suksamrarn ◽  
AH White
Keyword(s):  
Crystal Structure ◽  
Methyl Ester ◽  
Plant Growth ◽  
Structure Determination ◽  
Chemical Methods ◽  
X Ray ◽  
Aerial Parts ◽  
Iridoid Glucosides ◽  
Wheat Embryos ◽  
Growth Inhibiting

The minor iridoid glucosides present in the aerial parts of Barleria lupulina Lindl. ( Acanthaceae ) have been identified as ipolamiidoside (7) and the new compound 6-O-acetylshanzhiside methyl ester (3). The structure of (3) was determined by spectroscopic and chemical methods, and was confirmed by a single-crystal X-ray structure determination. Crystals of (3) are orthorhombic P212121, a 43.75(1), b 8.151(3), c 5.695(2) �, Z 4. The crystal structure was determined at 295 K from diffractometer data [I528 reflections with I > 3σ(I)] and refined to a residual of 0.043. Shanzhiside methyl ester (1) and its 6-Oacetyl (3), 8-Oacetyl (2) and 6,8-O,O-diacetyl (4) derivatives, all of which occur in Barleria lupulina, have been found to inhibit the growth of wheat embryos.

scholarly journals A New Diterpenoid from the Aerial Parts of Andrographis paniculata

2014 ◽  
Vol 9 (1) ◽  
pp. 1934578X1400900
Author(s):  
Chun-Hua Wang ◽  
Wen Li ◽  
Rui-Xia Qiu ◽  
Miao-Miao Jiang ◽  
Guo-Qiang Li
Keyword(s):  
Respiratory Syncytial Virus ◽  
Andrographis Paniculata ◽  
Spectrometric Analysis ◽  
Chemical Methods ◽  
Aerial Parts ◽  
Antiviral Activities ◽  
Syncytial Virus

One new and seven known diterpenoids were isolated from the aerial parts of Andrographis paniculata, and their structures elucidated on the basis of spectroscopic and spectrometric analysis, as well as chemical methods. The in vitro antiviral activities of these compounds against respiratory syncytial virus (RSV) were assayed.

A dihydrochalcone derivative and further steroidal saponins from Sansevieria trifasciata Prain

2017 ◽  
Vol 72 (11-12) ◽  
pp. 477-482 ◽  
Author(s):  
Billy T. Tchegnitegni ◽  
Rémy B. Teponno ◽  
Kristina Jenett-Siems ◽  
Matthias F. Melzig ◽  
Tomofumi Miyamoto ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Nuclear Magnetic Resonance ◽  
Spectroscopic Analysis ◽  
Ionization Mass ◽  
Steroidal Saponins ◽  
Chemical Methods ◽  
Aerial Parts ◽  
Phytochemical Investigation ◽  
Aconitic Acid ◽  
Related Compounds

AbstractPhytochemical investigation of the aerial parts ofSansevieria trifasciata, one of the most common Dracaenaceae plants, has resulted in the isolation of a new dihydrochalcone derivative named trifasciatine C (1), four previously unreported steroidal saponins as two pairs of inseparable regioisomers: trifasciatosides K/L (2/3), M/N (4/5), together with the known 1,2-(dipalmitoyl)-3-O-β-D-galactopyranosylglycerol (6), aconitic acid (7), and 1-methyl aconitic acid (8). Their structures were elucidated mainly by extensive spectroscopic analysis (1D and 2D nuclear magnetic resonance) and high-resolution electronspray ionization-mass spectrometry, as well as chemical methods and comparison of their spectral data with those of related compounds. Compounds2/3and4/5were evaluated for their antiproliferative activity on Hela cells, and no significant effect was observed.

A New Geniculatoside from Aerial Parts of Euphorbia geniculata Linn

ChemInform ◽  
2003 ◽  
Vol 34 (1) ◽  
pp. no-no
Author(s):  
A. Rahman ◽  
M. Ali ◽  
N. Z. Khan
Keyword(s):  
Aerial Parts ◽  
Euphorbia Geniculata

scholarly journals Prenylated Flavonoid Glycosides with PCSK9 mRNA Expression Inhibitory Activity from the Aerial Parts of Epimedium koreanum

Molecules ◽  
2021 ◽  
Vol 26 (12) ◽  
pp. 3590
Author(s):  
Eeray Kim ◽  
Young-Mi Kim ◽  
Jongmin Ahn ◽  
Hee-Sung Chae ◽  
Young-Won Chin ◽  
...  
Keyword(s):  
Mrna Expression ◽  
Inhibitory Activity ◽  
Soluble Fraction ◽  
Flavonoid Glycosides ◽  
Chemical Methods ◽  
Aerial Parts ◽  
Cholesterol Levels ◽  
Phytochemical Investigation ◽  
Ldl Uptake ◽  
New Compounds

Phytochemical investigation on the n-BuOH-soluble fraction of the aerial parts of Epimedium koreanum using the PCSK9 mRNA monitoring assay led to the identification of four previously undescribed acylated flavonoid glycosides and 18 known compounds. The structures of new compounds were elucidated by NMR, MS, and other chemical methods. All isolated compounds were tested for their inhibitory activity against PCSK9 mRNA expression in HepG2 cells. Of the isolates, compounds 6, 7, 10, 15, and 17–22 were found to significantly inhibit PCSK9 mRNA expression. In particular, compound 7 was shown to increase LDLR mRNA expression. Thus, compound 7 may potentially increase LDL uptake and lower cholesterol levels in the blood.

scholarly journals Sesquiterpene lactones from Centaurealinifolia Vahl

1978 ◽  
Vol 56 (4) ◽  
pp. 491-494 ◽  
Author(s):  
A. G. González ◽  
J. Bermejo ◽  
J. M. Amaro ◽  
G. M. Massanet ◽  
A. Galindo ◽  
...  
Keyword(s):  
Sesquiterpene Lactones ◽  
Chemical Methods ◽  
Aerial Parts ◽  
Physical And Chemical

Three new sesquiterpene lactones, linichlorins A, B, and C were isolated from the aerial parts of Centaurealinifolia Vahl and their structures were determined by physical and chemical methods. The sesquiterpene lactones chlorohyssopifolins A, B, C, D, E, aguerin B, and vahlenin were also isolated from the same plant.

scholarly journals Notizen: A New Pentaoxygenated Xanthone from the Fern Cystopteris fragilis

1990 ◽  
Vol 45 (11) ◽  
pp. 1603-1604 ◽  
Author(s):  
Filippo Imperato
Keyword(s):  
Chemical Methods ◽  
Aerial Parts

A new pentaoxigenated xanthone has been isolated from aerial parts of the fern Cystopteris fragilis. By spectroscopic and chemical methods this compound has been shown to be 1,6-dihydroxy-3,5,7-trimethoxyxanthone which is of biosynthetic interest in ferns.

Transmission Electron Microscopy of Protein Macromolecules

1971 ◽  
Vol 29 ◽  
pp. 424-425
Author(s):  
Henry S. Slayter
Keyword(s):  
Biological Systems ◽  
Metal Vapor ◽  
Resolving Power ◽  
Electron Microscopic ◽  
Chemical Methods ◽  
Molecular Weights ◽  
The Past ◽  
Physical Chemical ◽  
Transmission Electron

Electron microscopic methods have been applied increasingly during the past fifteen years, to problems in structural molecular biology. Used in conjunction with physical chemical methods and/or Fourier methods of analysis, they constitute powerful tools for determining sizes, shapes and modes of aggregation of biopolymers with molecular weights greater than 50, 000. However, the application of the e.m. to the determination of very fine structure approaching the limit of instrumental resolving power in biological systems has not been productive, due to various difficulties such as the destructive effects of dehydration, damage to the specimen by the electron beam, and lack of adequate and specific contrast. One of the most satisfactory methods for contrasting individual macromolecules involves the deposition of heavy metal vapor upon the specimen. We have investigated this process, and present here what we believe to be the more important considerations for optimizing it. Results of the application of these methods to several biological systems including muscle proteins, fibrinogen, ribosomes and chromatin will be discussed.

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