scholarly journals Guideline for Preventive Chemotherapy for the Control of Taenia solium Taeniasis

2021 ◽  
Keyword(s):  
Community Education ◽  
Guideline Development ◽  
Taenia Solium ◽  
Monitoring And Evaluation ◽  
World Health ◽  
Preventive Chemotherapy ◽  
Wide Audience ◽  
Full Life Cycle ◽  
Endemic Areas ◽  
Governmental Institutions

The larval stage of the parasite Taenia solium can encyst in the central nervous system causing neurocysticercosis, which is the main cause of acquired epilepsy in the countries in which the parasite is endemic. Endemic areas are those with the presence (or likely presence) of the full life cycle of Taenia solium. The parasite is most prevalent in poor and vulnerable communities in which pigs roam free, open defecation is practiced, basic sanitation is deficient, and health education is absent or limited. Several tools are available for the control of Taenia solium. Preventive chemotherapy for Taenia solium taeniasis, which is directed at the adult tapeworm, is one of them. Other tools focus on pig management, pig vaccination and treatment, sanitation and hygiene, and community education. Three potential drugs—niclosamide, praziquantel, and albendazole—have been considered for use for preventive chemotherapy in Taenia solium taeniasis control programs through mass drug administration or targeted chemotherapy. In this Guideline, we provide recommendations for preventive chemotherapy in Taenia solium-endemic areas using niclosamide, praziquantel, or albendazole, including at which dose and in which population groups. The development of this Guideline is based on the latest standard World Health Organization methods for guideline development, including the use of systematic search strategies, synthesis, quality assessment of the available evidence to support the recommendations, and participation of experts and stakeholders in the Guideline Development Group and External Review Group. The recommendations are intended for a wide audience, including policymakers and their expert advisers, and technical and program staff at governmental institutions and organizations involved in the planning, implementation, monitoring, and evaluation of preventive chemotherapy programs for the control of Taenia solium.

scholarly journals Associations between infection intensity categories and morbidity prevalence in school-age children are much stronger for Schistosoma haematobium than for S. mansoni

2021 ◽  
Vol 15 (5) ◽  
pp. e0009444
Author(s):  
Ryan E. Wiegand ◽  
W. Evan Secor ◽  
Fiona M. Fleming ◽  
Michael D. French ◽  
Charles H. King ◽  
...  
Keyword(s):  
Ultrasound Image ◽  
Infection Intensity ◽  
Control Program ◽  
Monitoring And Evaluation ◽  
World Health ◽  
Current Status ◽  
School Age Children ◽  
School Age ◽  
Preventive Chemotherapy ◽  
Urogenital Schistosomiasis

Background World Health Organization (WHO) guidelines for measuring global progress in schistosomiasis control classify individuals with Schistosoma spp. infections based on the concentration of excreted eggs. We assessed the associations between WHO infection intensity categories and morbidity prevalence for selected S. haematobium and S. mansoni morbidities in school-age children. Methodology A total of 22,488 children aged 6–15 years from monitoring and evaluation cohorts in Burkina Faso, Mali, Niger, Uganda, Tanzania, and Zambia from 2003–2008 were analyzed using Bayesian logistic regression. Models were utilized to evaluate associations between intensity categories and the prevalence of any urinary bladder lesion, any upper urinary tract lesion, microhematuria, and pain while urinating (for S. haematobium) and irregular hepatic ultrasound image pattern (C-F), enlarged portal vein, laboratory-confirmed diarrhea, and self-reported diarrhea (for S. mansoni) across participants with infection and morbidity data. Principal findings S. haematobium infection intensity categories possessed consistent morbidity prevalence across surveys for multiple morbidities and participants with light infections had elevated morbidity levels, compared to negative participants. Conversely, S. mansoni infection intensity categories lacked association with prevalence of the morbidity measures assessed. Conclusions/significance Current status infection intensity categories for S. haematobium were associated with morbidity levels in school-age children, suggesting urogenital schistosomiasis morbidity can be predicted by an individual’s intensity category. Conversely, S. mansoni infection intensity categories were not consistently indicative of childhood morbidity at baseline or during the first two years of a preventive chemotherapy control program.

scholarly journals A critical cartography of domestic violence policies in Mozambique

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Eunice Jethá ◽  
Ines Keygnaert ◽  
Mohamed Seedat ◽  
Joaquim Nhampoca ◽  
Mohsin Sidat ◽  
...  
Keyword(s):  
Domestic Violence ◽  
Monitoring And Evaluation ◽  
World Health ◽  
International Treaties ◽  
Office Visits ◽  
Strategic Action ◽  
National Policies ◽  
Critical Cartography ◽  
International Agencies ◽  
Governmental Institutions

Abstract Background Domestic violence (DV) affects millions of people worldwide, especially women impacting their health status and livelihoods. To prevent DV and to improve the quality of victims’ lives, Mozambican governmental and non-governmental entities are making efforts to develop adequate policies and legislation and to improve the accessibility of services for victims of DV. However, a critical review of whether or not current policies and legislation concerning DV in Mozambique are in agreement with international guidelines has yet to be examined. Therefore, this paper aims to map the Mozambican legislative and policy responses to DV. It also strives to analyse their alignment with international treaties and conventions and with each other. Methods Through a critical cartography, documents were selected and their content analysed. Some of these documents were not available online, printed versions were not available on the field and some were not up to date. Therefore, we had to search for them via physical office visits at governmental institutions with a responsibility to deal with DV aspects. These documents were listed and analysed for key content applying a framework inquiring on recommendations of international agencies such as World Health Organization. Subsequently, we compared these policies with international conventions and treaties of which Mozambique is signatory and with each other to identify discrepancies. Results Overall, six institutions were visited assuring identification of all available information and policy documents on DV. We identified a total of fifteen national DV documents of which five were on laws, one on policy and nine institutional strategic/action plans. Most of the national DV documents focused on strategies for assistance/care of victims and prevention of DV. Little focus was found on advocacy, monitoring and evaluation. Conclusions Mozambique has demonstrated its commitment by signing several international and regional treaties and conventions on DV. Despite this, the lack of consistency in the alignment of international treaties and conventions with national policies and laws is remarkable. However, a gap in the reliable translation of national policies and laws into strategic plans is to be found particularly in relation to naming type, beneficiaries, main strategies and multi-sectorial approach.

What works in water supply and sanitation projects in developing countries with EWB-USA

2016 ◽  
Vol 31 (1) ◽  
Author(s):  
Melissa J. Montgomery
Keyword(s):  
Drinking Water ◽  
Water Supply ◽  
Community Education ◽  
Monitoring And Evaluation ◽  
The Philippines ◽  
Lessons Learned ◽  
World Health ◽  
Human Needs ◽  
The World ◽  
Water Supply And Sanitation

AbstractThe World Health Organization (WHO) reports some progress on the global problem of a lack of improved water and sanitation. Between 1990 and 2012, the number of people that gained improved access to improved drinking water reached 2.3 billion people, while the number of children that have died from diarrheal diseases has fallen from 1.5 million deaths to just above 600,000 deaths (1, 2). However, it is estimated that there are still 1.8 billion people using a fecally contaminated source of drinking water (3). In addition, 748 million people continue to lack clean water, 1 billion continue to practice open defecation, and 2.5 billion people still lack adequate sanitation (3). In response to this global issue, Engineers Without Borders USA (EWB-USA) began with a mission to build a better world through engineering projects that empower communities to meet their basic human needs and equip leaders to solve the world’s most pressing challenges. Their 15,000+ members work with communities to find appropriate solutions to improve water supply, sanitation, energy, agriculture, civil works and structures. Their development approach is based on standard engineering methodology, including problem identification, assessment, alternatives analysis, implementation, and monitoring and evaluation. EWB-USA began in 2002 and currently has members working in over 40 countries around the world. The majority of their work is focused in Latin America and Africa, but their programs are expanding to Asia and the Pacific Basin. Currently, EWB-USA members are working in 17 programs in six countries, including the Philippines, Thailand, Cambodia, India, Nepal, and Fiji. Success in these programs is defined by measuring overall impact and learning from failure. Impact is measured through Standard Monitoring Indicators and learning is accomplished by documenting failures and lessons learned. Through this work, the organization has impacted 2.5 million lives through primarily water supply and sanitation projects by focusing on sustainable engineering solutions, community-education, capacity building, and appropriate technologies and local resources.

scholarly journals Control and elimination of schistosomiasis as a public health problem thresholds fail to differentiate schistosomiasis morbidity prevalence in children

2021 ◽  
Author(s):  
Ryan E Wiegand ◽  
W Evan Secor ◽  
Fiona M Fleming ◽  
Michael D French ◽  
Charles H King ◽  
...  
Keyword(s):  
Public Health ◽  
Health Problem ◽  
Public Health Problem ◽  
Monitoring And Evaluation ◽  
World Health ◽  
Preventive Chemotherapy ◽  
Schistosomiasis Control ◽  
Gates Foundation ◽  
Health Organization ◽  
The Relationship

Abstract Background Current World Health Organization guidelines utilize prevalence of heavy-intensity infections (PHI), i.e., ≥50 eggs per 10ml of urine for Schistosoma haematobium and ≥400 eggs per gram of stool for S. mansoni, to determine whether a targeted area has controlled schistosomiasis morbidity or eliminated schistosomiasis as a public health problem. The relationship between these PHI categories and morbidity is not well understood. Methods School-aged participants enrolled in schistosomiasis monitoring and evaluation cohorts from 2003-2008 in Burkina Faso, Mali, Niger, Uganda, Tanzania, and Zambia were surveyed for infection and morbidity at baseline and after 1 and 2 rounds of preventive chemotherapy. Logistic regression was used to compare morbidity prevalence among participants based on their school’s PHI category. Findings Microhematuria levels were associated with the S. haematobium PHI categories at all three time points. For any other S. haematobium or S. mansoni morbidity that was measured, PHI categories did not differentiate morbidity prevalence levels consistently. Interpretation These analyses suggest that current PHI categorizations do not differentiate the prevalence of standard morbidity markers. A reevaluation of the criteria for schistosomiasis control is warranted. Funding The Schistosomiasis Control Initiative (now the SCI Foundation) was supported by the Bill and Melinda Gates Foundation (grant 13122).

scholarly journals A living WHO guideline on drugs to prevent covid-19

BMJ ◽  
2021 ◽  
pp. n526
Author(s):  
François Lamontagne ◽  
Thomas Agoritsas ◽  
Reed Siemieniuk ◽  
Bram Rochwerg ◽  
Jessica Bartoszko ◽  
...  
Keyword(s):  
Systematic Review ◽  
Guideline Development ◽  
Meta Analysis ◽  
World Health ◽  
Policy And Practice ◽  
Assessment Development ◽  
Research Priority ◽  
Health Organization ◽  
Almost All ◽  
Drug Interventions

Abstract Clinical question What is the role of drugs in preventing covid-19? Why does this matter? There is widespread interest in whether drug interventions can be used for the prevention of covid-19, but there is uncertainty about which drugs, if any, are effective. The first version of this living guideline focuses on the evidence for hydroxychloroquine. Subsequent updates will cover other drugs being investigated for their role in the prevention of covid-19. Recommendation The guideline development panel made a strong recommendation against the use of hydroxychloroquine for individuals who do not have covid-19 (high certainty). How this guideline was created This living guideline is from the World Health Organization (WHO) and provides up to date covid-19 guidance to inform policy and practice worldwide. Magic Evidence Ecosystem Foundation (MAGIC) provided methodological support. A living systematic review with network analysis informed the recommendations. An international guideline development panel of content experts, clinicians, patients, an ethicist and methodologists produced recommendations following standards for trustworthy guideline development using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach. Understanding the new recommendation The linked systematic review and network meta-analysis (6 trials and 6059 participants) found that hydroxychloroquine had a small or no effect on mortality and admission to hospital (high certainty evidence). There was a small or no effect on laboratory confirmed SARS-CoV-2 infection (moderate certainty evidence) but probably increased adverse events leading to discontinuation (moderate certainty evidence). The panel judged that almost all people would not consider this drug worthwhile. In addition, the panel decided that contextual factors such as resources, feasibility, acceptability, and equity for countries and healthcare systems were unlikely to alter the recommendation. The panel considers that this drug is no longer a research priority and that resources should rather be oriented to evaluate other more promising drugs to prevent covid-19. Updates This is a living guideline. New recommendations will be published in this article and signposted by update notices to this guideline. Readers note This is the first version of the living guideline for drugs to prevent covid-19. It complements the WHO living guideline on drugs to treat covid-19. When citing this article, please consider adding the update number and date of access for clarity.

Urinary Schistosomiasis and Primary Evidence of Female Genital Schistosomiasis among Pupils in Nsugbe Community, Anambra State, Nigeria

2021 ◽  
Vol 42 (2) ◽  
pp. 394-402
Author(s):  
O.B. Aribodor ◽  
C.E. Okaka ◽  
S.O. Sam-Wobo ◽  
B.C. Okpala ◽  
D.N. Aribodor ◽  
...  
Keyword(s):  
Risk Factors ◽  
Test Strip ◽  
World Health ◽  
Effective Control ◽  
Preventive Chemotherapy ◽  
Water Contact ◽  
Urinary Schistosomiasis ◽  
Anambra State ◽  
Health Organization ◽  
Female Genital

Urinary schistosomiasis is considered a major public health parasitic disease in African communities. Prior to this study, Nsugbe community was not considered endemic for the disease and as such was not involved in Praziquantel-Preventive Chemotherapy (PC). Longitudinal study of 281 consented pupils aged 5-16 years was carried out with aim of determining the status of urinary schistosomiasis. Urinalysis laboratory test strip, urine filtration technique and syndromic diagnosis were used for the confirmation of the presence of haematuria in urine samples, identification of Schistosoma haematobium ova and the confirmation of female genital schistosomiasis (FGS), respectively. Risk factors for urinary schistosomiasis infection were determined using pre-tested structured questionnaire. Data were analyzed using Minitab 17 software and intensity of infection categorized following World Health Organization (WHO) recommendations. Of the 281 pupils, 117 (42%) were males and 164 (58%) were females with mean age of 9 years. At baseline, an overall prevalence of 0.4% (1/281) which was of light intensity was established. At follow-up, an overall prevalence of 2.1% (6/281) which was of both light (16.7%) and heavy infection (83.3%) was established. The result of the clinical examination showed eggs of S. haematobium in and around the vaginal area indicating FGS of a female pupil aged 12 years. This was treated. Identified risk factors for S. haematobium infection in the community include water-contact activities, ignorance, source of water supply among others. The study revealed the need for an all inclusive mass administration of Praziquantel-PC in the study community for effective control and possible elimination.

scholarly journals Sodium Levels of Processed Meat in Australia: Supermarket Survey Data from 2010 to 2017

Nutrients ◽  
2018 ◽  
Vol 10 (11) ◽  
pp. 1686 ◽  
Author(s):  
Emalie Sparks ◽  
Clare Farrand ◽  
Joseph Santos ◽  
Briar McKenzie ◽  
Kathy Trieu ◽  
...  
Keyword(s):  
Sodium Intake ◽  
Meat Products ◽  
Monitoring And Evaluation ◽  
Sodium Content ◽  
World Health ◽  
Processed Meat ◽  
High Sodium ◽  
Processed Meats ◽  
Health Organization ◽  
Health Dialogue

High sodium intake increases blood pressure and consequently increases the risk of cardiovascular diseases. In Australia, the best estimate of sodium intake is 3840 mg sodium/day, almost double the World Health Organization (WHO) guideline (2000 mg/day), and processed meats contribute approximately 10% of daily sodium intake to the diet. This study assessed the median sodium levels of 2510 processed meat products, including bacon and sausages, available in major Australian supermarkets in 2010, 2013, 2015 and 2017, and assessed changes over time. The median sodium content of processed meats in 2017 was 775 mg/100 g (interquartile range (IQR) 483–1080). There was an 11% reduction in the median sodium level of processed meats for which targets were set under the government’s Food and Health Dialogue (p < 0.001). This includes bacon, ham/cured meat products, sliced luncheon meat and meat with pastry categories. There was no change in processed meats without a target (median difference 6%, p = 0.450). The new targets proposed by the current government’s Healthy Food Partnership capture a larger proportion of products than the Food and Health Dialogue (66% compared to 35%) and a lower proportion of products are at or below the target (35% compared to 54%). These results demonstrate that voluntary government targets can drive nutrient reformulation. Future efforts will require strong government leadership and robust monitoring and evaluation systems.

scholarly journals Assessing the performance of mental health service facilities for meeting patient priorities and health service responsiveness

2016 ◽  
Vol 25 (5) ◽  
pp. 417-421 ◽  
Author(s):  
A. Bramesfeld ◽  
C. Stegbauer
Keyword(s):  
Mental Health ◽  
Mental Health Service ◽  
Health Service ◽  
Performance Monitoring ◽  
Guideline Development ◽  
World Health ◽  
Monitoring Programs ◽  
Mental Health Patients ◽  
Health Service Responsiveness

The World Health Organisation has defined health service responsiveness as one of the key-objectives of health systems. Health service responsiveness relates to the ability to respond to service users’ legitimate expectations on non-medical issues when coming into contact with the services of a healthcare system. It is defined by the areas showing respect for persons and patient orientation. Health service responsiveness is particularly relevant to mental health services, due to the specific vulnerability of mental health patients but also because it matches what mental health patients consider as good quality of care as well as their priorities when seeking healthcare. As (mental) health service responsiveness applies equally to all concerned services it would be suitable as a universal indicator for the quality of services’ performance. However, performance monitoring programs in mental healthcare rarely assess health service performance with respect to meeting patient priorities. This is in part due of patient priorities as an outcome being underrepresented in studies that evaluate service provision. The lack of studies using patient priorities as outcomes transmits into evidence based guidelines and subsequently, into underrepresentation of patient priorities in performance monitoring. Possible ways out of this situation include more intervention studies using patient priorities as outcome, considering evidence from qualitative studies in guideline development and developing performance monitoring programs along the patient pathway and on key-points of relevance for service quality from a patient perspective.

scholarly journals Reducing the Risk of Cognitive Decline and Dementia: WHO Recommendations

2022 ◽  
Vol 12 ◽  
Author(s):  
Neerja Chowdhary ◽  
Corrado Barbui ◽  
Kaarin J. Anstey ◽  
Miia Kivipelto ◽  
Mariagnese Barbera ◽  
...  
Keyword(s):  
Cognitive Decline ◽  
Risk Reduction ◽  
Social Care ◽  
Guideline Development ◽  
Action Plan ◽  
World Health Organisation ◽  
World Health ◽  
Public Health Response ◽  
Health And Social Care ◽  
The World

With population ageing worldwide, dementia poses one of the greatest global challenges for health and social care in the 21st century. In 2019, around 55 million people were affected by dementia, with the majority living in low- and middle-income countries. Dementia leads to increased costs for governments, communities, families and individuals. Dementia is overwhelming for the family and caregivers of the person with dementia, who are the cornerstone of care and support systems throughout the world. To assist countries in addressing the global burden of dementia, the World Health Organisation (WHO) developed the Global Action Plan on the Public Health Response to Dementia 2017–2025. It proposes actions to be taken by governments, civil society, and other global and regional partners across seven action areas, one of which is dementia risk reduction. This paper is based on WHO Guidelines on risk reduction of cognitive decline and dementia and presents recommendations on evidence-based, multisectoral interventions for reducing dementia risks, considerations for their implementation and policy actions. These global evidence-informed recommendations were developed by WHO, following a rigorous guideline development methodology and involved a panel of academicians and clinicians with multidisciplinary expertise and representing geographical diversity. The recommendations are considered under three broad headings: lifestyle and behaviour interventions, interventions for physical health conditions and specific interventions. By supporting health and social care professionals, particularly by improving their capacity to provide gender and culturally appropriate interventions to the general population, the risk of developing dementia can be potentially reduced, or its progression delayed.

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