scholarly journals DYSMORPHISMS OF OOCYTES IN ART PROCEDURES. LITERATURE REVIEW

2021 ◽  
pp. 63-70
Author(s):  
G.M. Karibayeva ◽  
S.I. Tevkin ◽  
T.M. Jussubaliyeva ◽  
M.S. Shishimorova
Keyword(s):  
Clinical Practice ◽  
In Vitro Fertilization ◽  
Assisted Reproductive Technologies ◽  
Morphological Characteristics ◽  
Reproductive Technologies ◽  
Clinical Pregnancy ◽  
Vitro Fertilization ◽  
Analysis Of Results

Currentliterature review presents the analysis of results of studies of morphological qualities and anomalies (dysmorphisms) of human oocytes in the field of assisted reproductive technologies. The variety of intracytoplasmic anomalies encountered in the clinical practice of in vitro fertilization, their effect on fertilization, cleavage, implantation frequency, clinical pregnancy rate were described. Moreover, the morphological characteristics of oocyte could be considered to use as biomarkers in predicting the quality of embryos and blastocysts, and further implantation potential.

Legal restrictions on pre-implantation genetic diagnostics in the framework of in vitro fertilization procedure: foreign experience and Russian perspective

2019 ◽  
Author(s):  
N.A. Altinnik , S.S. Zenin , V.V. Komarova et all
Keyword(s):  
In Vitro Fertilization ◽  
Assisted Reproductive Technologies ◽  
Genetic Diseases ◽  
Genetic Diagnosis ◽  
Reproductive Technologies ◽  
Legal Regulation ◽  
Genetic Diagnostics ◽  
Vitro Fertilization ◽  
Medical Indications

The article discusses the factors that determine the content of the legal limitations of pre-implantation genetic diagnosis in the framework of the in vitro fertilization procedure, taking into account international experience and modern domestic regulatory legal regulation of the field of assisted reproductive technologies. The authors substantiates the conclusion that it is necessary to legislate a list of medical indications for preimplantation genetic diagnosis, as well as the categories of hereditary or other genetic diseases diagnosed in the framework of this procedure.

scholarly journals Prevalence of pathogenic copy number variants among children conceived by donor oocyte

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Sandra Monfort ◽  
Carmen Orellana ◽  
Silvestre Oltra ◽  
Mónica Rosello ◽  
Alfonso Caro-Llopis ◽  
...  
Keyword(s):  
In Vitro Fertilization ◽  
Copy Number ◽  
Assisted Reproductive Technologies ◽  
Copy Number Variants ◽  
Reproductive Technologies ◽  
Significant Excess ◽  
Vitro Fertilization ◽  
Donor Oocyte ◽  
Increased Risk

AbstractDevelopment of assisted reproductive technologies to address infertility has favored the birth of many children in the last years. The majority of children born with these treatments are healthy, but some concerns remain on the safety of these medical procedures. We have retrospectively analyzed both the fertilization method and the microarray results in all those children born between 2010 and 2019 with multiple congenital anomalies, developmental delay and/or autistic spectrum disorder (n = 486) referred for array study in our center. This analysis showed a significant excess of pathogenic copy number variants among those patients conceived after in vitro fertilization with donor oocyte with respect to those patients conceived by natural fertilization (p = 0.0001). On the other hand, no significant excess of pathogenic copy number variants was observed among patients born by autologous oocyte in vitro fertilization. Further studies are necessary to confirm these results and in order to identify the factors that may contribute to an increased risk of genomic rearrangements, as well as consider the screening for genomic alterations after oocyte donation in prenatal diagnosis.

scholarly journals GAMETE DONATION. ETHICAL AND LEGAL ASPECTS

2020 ◽  
pp. 13-19
Author(s):  
L. Chalova ◽  
V. Lokshin ◽  
A. Guseva ◽  
A. Kinzhibayev
Keyword(s):  
In Vitro Fertilization ◽  
Literature Review ◽  
World Literature ◽  
Assisted Reproductive Technologies ◽  
Reproductive Technologies ◽  
Legal Aspects ◽  
Gamete Donation ◽  
Vitro Fertilization ◽  
National Legislation

This world literature review tries to determine the significance of the gamete donation in the field of assisted reproductive technologies as well as the availability of treatment methods using donation in in vitro fertilization programs. Gamete donation is regulated by every country's national legislation system, and quite often the laws vary between the states. There are practically no universal standards and/or rules in this area, which, in turn, leads to an ambivalent reaction towards reproductive practices.

scholarly journals Islam, Assisted Reproductive Technologies, and the Middle Eastern State

1970 ◽  
Author(s):  
Marcia C. Inhorn
Keyword(s):  
In Vitro Fertilization ◽  
Assisted Reproductive Technologies ◽  
Middle Eastern ◽  
Reproductive Technologies ◽  
Third Party ◽  
Vitro Fertilization ◽  
Eastern State ◽  
Nation States

Assisted reproductive technologies, such as in vitro fertilization, have made their way to the Middle Eastern nation states. However, in the Sunni-dominant countries, third-party donation of sperm, eggs, embryos, and uteruses (as in surrogacy) is banned, leading some Sunni Muslim couples to travel to Iran and Lebanon, where Shia Muslim clergy have allowed donor technologies.

Assisted reproductive technologies and their impact on a woman's body

2021 ◽  
pp. 239-242
Author(s):  
A.A. Fil ◽  
◽  
E.L. Sorokin ◽  
O.V. Kolenko ◽  
◽  
...  
Keyword(s):  
In Vitro Fertilization ◽  
Assisted Reproductive Technologies ◽  
Reproductive Technologies ◽  
Vascular Pathology ◽  
Timely Manner ◽  
Fertilization Program ◽  
Vitro Fertilization ◽  
Hemostatic System ◽  
Retinal Pathology

A review of the literature data is presented, which indicates the possible influence of assisted reproductive technologies (ART) on the formation of both systemic and retinal vascular pathology. Despite the fact that the overall incidence of thromboembolic complications as a result of the use of ART is low, nevertheless, in women included in the in vitro fertilization program, their risk increases by 10 times. Therefore, due to the adverse effect of these drugs on the hemostatic system of a woman, ophthalmologists should be more wary of them in order to detect vascular retinal pathology in a timely manner. Key words: assisted reproductive technologies, in vitro fertilization, hyperestrogenism, vascular retinal pathology.

Trends in safe infertility treatment with assisted reproductive technologies

2020 ◽  
Vol 69 (4) ◽  
pp. 83-88
Author(s):  
Svetlana S. Paskar ◽  
Alla S. Kalugina ◽  
Anna G. Tkachuk
Keyword(s):  
Clinical Practice ◽  
Assisted Reproductive Technology ◽  
Assisted Reproductive Technologies ◽  
Perinatal Outcomes ◽  
Reproductive Technologies ◽  
Infertility Treatment ◽  
Reproductive Technology ◽  
Correct Prediction ◽  
Vitro Fertilization

The expansion of indications for assisted reproductive technology has led to significant implications for assisted reproductive technology (ART) programs worldwide. More than 7 million children in the world were born using ART. Modern clinical practice in the field of reproductive sciences is aimed not only at increasing the effectiveness, but also at the safety of treatment. ART, like any other type of therapy, may be combined with negative side effects. Both the correct prediction of the risks associated with treatment and a personalized approach ensure the absolute safety of infertility treatment using in vitro fertilization. In this regard, over the past decade, a number of new research approaches have been noted that use ART methods integrated into clinical practice: cycle segmentation with subsequent embryo transfer and the elective transfer of one embryo. New approaches provide a control in relation to ovarian stimulation and a reduction in the number of transferred embryos, which helps to minimize primarily adverse perinatal outcomes. Predicting the risks and outcomes of treatment using mathematical modeling is the application of good clinical practice.

Stateof-the-art of realization of the fertility potential in the women of late reproductive age

2016 ◽  
Vol 94 (1) ◽  
pp. 10-15
Author(s):  
Kristina S. Ermolenko ◽  
V. E. Radzinsky ◽  
S. I. Rapoport
Keyword(s):  
In Vitro Fertilization ◽  
Reproductive Technologies ◽  
Reproductive Age ◽  
Vitro Fertilization ◽  
Biological Potential ◽  
Reproductive Material ◽  
Seasonal Biorhythms

Biological potential of childbearing in the women of late reproductive age is limited by natural impairment and loss of fertility. Despite a considerable progress in clinical application of new diagnostic and reproductive technologies, the problem of infertility remains a most serious challenge. Women’s age is one of the main factors responsible for the outcome of in vitro fertilization. The low effectiveness of in vitro fertilization programs is attributed to discoordination in the hypothalamic-pituitary system, depletion of ovarian resources, and deterioration of quality of reproductive material. Bearing in mind the role of melatonin in synchronizing circadian and seasonal biorhythms and regulating physiological and pathological processes, it is natural to suggest its role in the enhancement of efficiency of in vitro fertilization programs for women of late reproductive age.

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