Controlled Release of Drug Thymol from poly(Acrylamide-co-2-acrylamido-2-methylpropanesulfonic acid) Silver nanocomposite Hydrogel

2021 ◽  
Vol 15 (3) ◽  
Keyword(s):  
Controlled Release ◽  
Nanocomposite Hydrogel ◽  
Silver Nanocomposite ◽  
Silver Nanocomposite Hydrogel ◽  
Poly Acrylamide

scholarly journals PREPARATION AND ANTIBACTERIAL ACTIVITY OF CMC-g-P (SPMA)/SILVER NANOCOMPOSITE HYDROGEL

2019 ◽  
Vol 53 (5-6) ◽  
pp. 509-516 ◽  
Author(s):  
AHMED SALAMA ◽  
◽  
MAHA A. YOUSSEF ◽  
ABEER A. HASSAN ◽  
NASSER S. AWWAD ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Nanocomposite Hydrogel ◽  
Silver Nanocomposite ◽  
Silver Nanocomposite Hydrogel

scholarly journals Synthesis of silver nanocomposite hydrogels based on Poly (acrylic acid) and Poly (vinyl pyrrolidone) grafted onto Salep biopolymer and its use in drug release

2021 ◽  
Vol 12 (3) ◽  
pp. 662-668
Author(s):  
Ghasem Rezanejade Bardajee ◽  
Hanieh Mostashfi ◽  
Zari Hooshyar
Keyword(s):  
Electron Microscopy ◽  
Side Effects ◽  
Drug Release ◽  
Controlled Drug Release ◽  
Drug Dose ◽  
Vinyl Pyrrolidone ◽  
Nanocomposite Hydrogel ◽  
Silver Nanocomposite ◽  
Poly Vinyl Pyrrolidone ◽  
Silver Nanocomposite Hydrogel

This study aimed to synthesize a silver nanocomposite hydrogel based on poly (acrylic acid) and poly (vinyl pyrrolidone) grafted onto salep biopolymer and its use in controlled drug release. Drug release is one of the medicine goals that have been happening in the different methods, such as injections, pills or sprays. The useful drug dose, has measured by the drug concentration in the blood system, in the specific time. Researches have shown, in above methods, at the first time there is a high concentration of drug in the blood and by passing the time, this concentration decreases, so for achieve the useful drug dose, more drug is needed which it usually causes the increasing of the drug side effects. Thus for preventing these side effects, controlled drug release is investigated in this research. To identify the synthesized hydrogel, Fourier transform infrared spectroscopy (FTIR, scanning electron microscopy (SEM), transmission electron microscopy (TEM), and thermometric gravimetric analysis (TGA) were used. The results showed that the release of deferasirox from the silver nanocomposite hydrogel network is related to the pH of the environment. In addition, the biodegradability and biocompatibility of this system have led to its use in the pharmaceutical industry.

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