scholarly journals THE CORRELATION BETWEEN THE APPEARANCE OF NON-MELANOCYTIC SKIN TUMORS AND EXPOSURE TO UV RADIATION

2021 ◽  
Vol 68 (2) ◽  
pp. 219-224
Author(s):  
Ana-Maria Cioti ◽  
◽  
Oana Nicolescu ◽  
Ioana Veronica Grăjdeanu ◽  
Alexandru Mihai Stefanescu ◽  
...  
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Histopathological Examination ◽  
Family Doctor ◽  
Skin Tumors ◽  
Presumptive Diagnosis ◽  
Study Results ◽  
The Family ◽  
Icd 10

Introduction. In the last 30 years, the incidence of non-melanocytic skin tumors (NMRTs) has increased alarmingly. The most common subtype of TCNM is basal cell carcinoma followed by squamous cell carcinoma. Material and method. This retrospective study was performed on a group of 140 patients. Patients diagnosed with C44 nonmelanocytic malignancy according to ICD-10 were included in the study. Results. Of the 140 patients, 118 (84%) received the presumptive diagnosis of CBC and 17 (12%) the diagnosis of CSC. Histopathological examination confirmed the diagnosis of CBC in 76% of cases and that of CSC in 58% of cases. Regarding the number of lesions, cases with a single lesion predominate (94%). In terms of clinical form, the most common type of basal cell carcinoma in the study group was 75% nodular carcinoma. Conclusions. There is a need for more studies for the application of prevention and proper management from the family doctor to the specialist.

scholarly journals Large Basal Cell Carcinoma Defect Closure on The Lateral Cheek Using Multiple Advancement Flaps

2021 ◽  
pp. 1-7
Author(s):  
Siswanto Wahab ◽  
Khairuddin Djawad
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Histopathological Examination ◽  
Skin Flap ◽  
Reconstruction Procedure ◽  
The Face ◽  
Advancement Flaps ◽  
Substantial Morbidity

Basal cell carcinoma (BCC) is the most common type of nonmelanoma skin cancer (NMSC). It grows slowly and very rarely metastasizes but can cause substantial morbidity due to its tendency to relapse and locally invasive nature, especially when located on the face. Excision surgery is still the gold standard treatment for primary BCC and is usually followed by reconstruction procedure. Skin flap techniques vary widely, one of which is flap advancement technique. The main benefit of flap advancement technique is the ability to hide the excision line, thus resulting in an aesthetically sound outcome. We report a case of 72-year-old female with hyperpigmented plaque brownish lump on the left lateral cheek. A diagnosis of igmented basal cell carcinoma had been confirmed through histopathological examination. The patient was treated with wide excision surgery and the defect was closed by multiple advancement flaps. Follow-up after three months showed excellent cosmetic and functional outcome.

scholarly journals Dermoscopic Features of Basal Cell Carcinoma

2018 ◽  
Vol 35 (4) ◽  
pp. 273-281
Author(s):  
Danica Tiodorović ◽  
Andrija Jović ◽  
Danijela Popović ◽  
Hristina Kocić ◽  
Aleksandra Ignjatović ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Basal Cell ◽  
Skin Tumors ◽  
Clinical Type ◽  
Reliable Diagnosis ◽  
The Moment

Abstract The aim of this study was to analyze the dermoscopic features in patients with pathohistologically confirmed basal cell carcinoma (BCC). Our retrospective study included 54 patients with 76 BCCs in total, diagnosed in 2016 and 2017. All lesions were classified into four clinical types: nodular, pigmented, superficial and infiltrative. Digital dermoscopic images were evaluated by three observers. We selected five dermoscopic features for analysis, including: the absence of pigment network, the presence of arborizing vessels, blue-gray globules and ovoid nests, leaf-like areas and ulcerations. In the total of 54 patients, there were 22 females and 32 males. At the moment of establishing the diagnosis, the patients’ age was in the range from 31 to 84 years (median age 67 years). The most frequent clinical type was the nodular type with 28 confirmed diagnoses. Nodular BCC was more frequently localized on the head and neck areas compared to the trunk and limbs (p < 0.01). Dermoscopically, the absence of pigmented network was verified in all cases. Arborizing vessels were present in 71 (93.4%) lesions, blue-gray globules and ovoid nests in 33 (42.1%), ulcerations in 44 (57.9%), and leaf-like areas in 5 (6.6%) lesions. Blue-gray globules and ovoid nests were significantly frequent in pigmented BCC in comparison to other clinical types of BCC (p < 0.01). In conclusion, using dermoscopy, it is entirely possible to make a reliable diagnosis of BCC as well as to differentiate it from others skin tumors.

scholarly journals Concurrent primary and secondary myiasis on basal cell carcinoma

2012 ◽  
Vol 87 (2) ◽  
pp. 292-295 ◽  
Author(s):  
Adriana Andrade Raposo ◽  
Antônio Pedro Mendes Schettini ◽  
Cesare Massone
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Histopathological Examination ◽  
Traumatic Injury ◽  
Skin Condition ◽  
Healthy Patient ◽  
Dorsal Region ◽  
Skin Cancers ◽  
Fly Larvae

Myiasis is a disease caused by infestation of fly larvae in human and other vertebrate tissues. It is a skin condition common in tropical and subtropical countries and its predisposing factors are: chronic diseases, immunodeficiency, poor hygiene, senility, psychiatric disorders, skin cancers and ulcerated mucosae. We report the case of a healthy patient who after traumatic injury of a preexisting lesion showed a tumor on the dorsal region parasitized by fly larvae. The histopathological examination performed for the diagnosis of skin neoplasm surprisingly revealed the presence of a partially degenerated larva with characteristics of Dermatobia hominis, suggesting an association of primary and secondary myiasis on basal cell carcinoma.

Metatypical basal cell carcinoma in young man

2016 ◽  
Vol 19 (3) ◽  
pp. 132-136
Author(s):  
Elena S. Snarskaya ◽  
L. R Plieva ◽  
I. S Maximov
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Historical Data ◽  
Distant Metastases ◽  
Skin Tumors ◽  
Recombinant Interferon ◽  
Clinical Investigations ◽  
Frequent Relapses ◽  
Oncological Diseases

Malignant epithelial skin tumors are leading among oncological diseases worldwide. In most cases epithelial skin tumors affect areas, susceptible to the action of adverse environmental factors. Metatypical basal cell carcinoma is a variant of basal cell carcinoma that combines the features of basal cell and squamous cell carcinomas. It characterized by infiltrative growth and the destruction of the underlying tissues, pain, bleeding, formation of distant metastases and frequent relapses. Metatypical basal cell carcinoma is more common in women, with the average age is 70.5 years. Historical data, the results of own clinical investigations, rare case of metatypical basal cell carcinoma of the young man, who was successfully treated with recombinant interferon-a2 and prospidinum are presented.

The Vasculature of Nonmelanocytic Skin Tumors in Reflectance Confocal Microscopy: Vascular Features of Basal Cell Carcinoma

2010 ◽  
Vol 146 (3) ◽  
Author(s):  
Verena Ahlgrimm-Siess ◽  
Theresa Cao ◽  
Margaret Oliviero ◽  
Rainer Hofmann-Wellenhof ◽  
Harold S. Rabinovitz ◽  
...  
Keyword(s):  
Confocal Microscopy ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Skin Tumors ◽  
Reflectance Confocal Microscopy

scholarly journals Comparison of BCL-2 Ecpression in Periocular Basal Cell Carcinoma Aggressive and Non-Aggressive Types in Mohammad Hoesin Hospital Palembang

2018 ◽  
Vol 1 (2) ◽  
pp. 18-36
Author(s):  
Fera Yunita Rodhiaty ◽  
Ika Kartika ◽  
Ibrahim
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Malignant Tumor ◽  
Histopathological Examination ◽  
Basal Layer ◽  
Growth Patterns ◽  
Bivariate Analysis ◽  
Fisher Exact Test ◽  
Cross Sectional

Abstract Background: Basal cell carcinoma (BCC) is a malignant tumor originating from non- keratinizing cells originating from the basal layer of the epidermis. Basal cell carcinoma is the most common malignant tumor, nearly 90% of all non-melanoma skin cancers. Clinically, BCC is difficult to distinguish, final diagnosis determined based on histopathological examination of complete tumor tissue. Based on histological growth patterns, BCC is divided into two, non- aggressive type (nodular and superficial) and aggressive type (infiltration, micronodular, fibroepithelial, basoskuamosa, keratotic, adnexal differentiation). The examination technique by analyzing the proteins or genes involved is related to the aggressiveness of basal cell carcinoma. Objective: This study was conducted to determine the comparison of expression of Bcl-2 in periocular basal type aggressive and non-aggressive carcinomas in dr. Mohammad Hoesin Palembang. Methodology: A cross sectional analytic study from 26 periocular basal cell carcinoma patients in RSUP dr. Mohammad Hoesin Palembang, January 2014- June 2018. Histopathologic features were examined with hematoxylin-eosine staining and imunohistochemical were examined with Bcl-2 monoclonal antibody. Data were analyzed by bivariate analysis, using chi-square test and fisher exact test. Results: Positive Bcl-2 expression was more common in periocular basal cell carcinoma (93.8%) than aggressive (50%), and nodular type (93.8%) compared to other types of histological differentiation. Positive Bcl-2 expression was also higher in female patients (90.9%) than males (66.7%). There is a significant relationship between expression of Bcl-2 and growth patterns, differentiation of cell histology and also sex of patients with basal cell carcinoma. Conclusion: In this study, there was a significant correlation between expression of Bcl-2 and aggressive and non-aggressive periocular basal cell carcinoma in RSUP dr. Mohammad Hoesin Palembang.

scholarly journals Pigmented Paraaxillary Located "Complex" Basal Cell Carcinoma Imitating clinically irritated Melanocytic Lesion - Succesfull Surgical Approach in Bulgarian Patient

2017 ◽  
Vol 5 (4) ◽  
pp. 497-500
Author(s):  
Cristiana Voicu ◽  
Mara Mihai ◽  
Mihai Lupu ◽  
James W. Patterson ◽  
Nely Koleva ◽  
...  
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Histopathological Examination ◽  
Surgical Excision ◽  
Melanocytic Lesion ◽  
Complete Surgical Excision ◽  
Axillary Region ◽  
The Right ◽  
Clinical Subtype

BACKGROUND: Basal cell carcinoma (BCC) is the most frequently encountered neoplasm worldwide. While nodular BCC is the most frequent clinical subtype, other forms of BCC, such as superficial, cystic, morpheiform, infiltrative, and pigmented may also be encountered.CASE PRESENTATION: We present the case of a 67-year-old male with a relatively well-defined infiltrative, pigmented plaque with multiple colours and peripheral growth situated in the right axillary region. The histopathologic examination performed after complete surgical excision of the tumour revealed a complex pigmented BCC with macronodular, fibroepithelioma-like, cystic, focally infiltrative and basosquamous features.CONCLUSION: Uncommon locations of BCCs in sun-protected areas such as the axillary region require a higher degree of suspicion for diagnosis. The complex histology of the presented case, including subtypes with differing biologic attributes, emphasises the importance of histopathological examination in the diagnosis and therapeutic management of BCC.

scholarly journals Clinical and Dermoscopic Factors for the Identification of Aggressive Histologic Subtypes of Basal Cell Carcinoma

2021 ◽  
Vol 10 ◽  
Author(s):  
Riccardo Pampena ◽  
Gabriele Parisi ◽  
Mattia Benati ◽  
Stefania Borsari ◽  
Michela Lai ◽  
...  
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Multivariate Regression Analysis ◽  
Histologic Subtype ◽  
Logistic Regression Models ◽  
Surgical Recurrence ◽  
Study Results ◽  
Before And After ◽  
Histologic Subtypes

BackgroundInfiltrative basal cell carcinoma (BCC) has a higher risk for post-surgical recurrence as compared to the most common low-aggressive superficial and nodular BCC. Independent diagnostic criteria for infiltrative BCC diagnosis have not been still defined. Improving the pre-surgical recognition of infiltrative BCC might significantly reduce the risk of incomplete excision and recurrence.ObjectiveThe aim of this study is to define clinical and dermoscopic criteria that can differentiate infiltrative BCC from the most common low-aggressive superficial and nodular BCC.MethodsClinical and dermoscopic images of infiltrative, superficial, and nodular BCC were retrospectively retrieved from our database and jointly evaluated by two experienced dermoscopists, blinded for the histologic subtype. Pairwise comparisons between the three histologic subtypes were performed and multivariable logistic regression models were constructed in order to define clinical and dermoscopic factors independently associated with each subtype. To validate our findings, two experienced dermoscopists not previously involved in the study were asked to evaluate clinical and dermoscopic images from an external dataset, guessing the proper BCC subtype between infiltrative, nodular and superficial, before and after being provided with the study results.ResultA total of 481 histopathologically proven BCCs (51.4% nodular, 33.9% superficial, and 14.8% infiltrative) were included. We found that infiltrative BCC mostly appeared on the head and neck as an amelanotic hypopigmented plaque or papule, displaying ulceration on dermoscopic examination, along with arborizing and fine superficial telangiectasia. Shiny white structures were also frequently observed. Multivariate regression analysis allowed us to define a clinical-dermoscopic profile of infiltrative BCC.ConclusionsWe defined the clinical-dermoscopic profile of infiltrative BCC, allowing to differentiate this variant from superficial and nodular BCC. This will improve pre-surgical recognition of infiltrative forms, reducing the risk for post-surgical recurrence.

scholarly journals Spontaneous Regression of Annular Basal Cell Carcinoma: A Case Report

2019 ◽  
Vol 11 (2) ◽  
pp. 145-149
Author(s):  
Usho Go ◽  
Kazunori Miyata ◽  
Masaru Fujita ◽  
Takashi Ohide ◽  
Tsuyoshi Mitsuishi
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Spontaneous Regression ◽  
Histopathological Examination ◽  
Sweat Glands ◽  
Temporal Region ◽  
Japanese Male ◽  
Old Japanese ◽  
The Right

We herein present a case of annular basal cell carcinoma (BCC) with spontaneous regression on the right temporal region of a 56-year-old Japanese male. Histopathological examination revealed that the central section had no tumor cells. The sweat glands, follicles, and other cutaneous appendages were also absent. This pattern of spontaneous regression is quite uncommon, and understanding the histopathology may be important for future approaches to BCC.

Sign in / Sign up

Export Citation Format

Share Document