scholarly journals Tratamiento De COVID-19. Mitos Y Realidades Bajo La Perspectiva De La Investigación Clínica [Treatment Of COVID-19. Myths And Realities Under The Perspective Of Clinical Research]

2020 ◽  
Vol 24 (2) ◽  
Author(s):  
Osvaldo Reyes
Keyword(s):  
Clinical Research ◽  
Key Words ◽  
Scientific Community ◽  
The World ◽  
The Future

<p>Resumen</p><p>La enfermedad producida por el SARS-CoV-2, conocida como COVID-19 (Coronavirus Disease 19), ha puesto el mundo en pausa y generado una respuesta masiva de la comunidad científica en todo el mundo, buscando una cura. Sin embargo, el deseo de obtener un tratamiento nunca debe ir por encima de la rigurosidad del proceso y, desafortunadamente, cada cierto tiempo aparece alguna noticia o publicación garantizando que cierto medicamento ha demostrado dar buenos resultados. Estas conclusiones, muchas veces, distan de la realidad, cuando se analiza la investigación que sustenta dicha aseveración. En este artículo reviso la evidencia disponible a la fecha sobre los potenciales tratamientos para el COVID-19, analizando las debilidades y fortalezas de cada uno y su potencial para el futuro.</p><p>Palabras claves: COVID-19, tratamiento, hidroxicloroquina,remdesivir, lopinavir, ritonavir, ivermectina, tocilizumab, suero convaleciente.<em></em></p><p><em>Abstract:</em></p><p><em>The disease produced by SARS-CoV-2, known as COVID-19 (Coronavirus Disease 19), has put the world on hold and generated a massive response from the scientific community worldwide in search of a cure. However, the desire to obtain a treatment should never override the rigor of the process and unfortunately, every so often there is some news or publication guaranteeing that a certain drug has been shown to work. These conclusions are often far from the truth when the research supporting the claim is scrutinized. In this article, I review the evidence to date on potential treatments for COVID-19, analyzing the strengths and weaknesses of each and its potential for the future.</em></p><p><em>Key words: COVID-19, treatment, hydroxychloroquine, remdesivir, lopinavir, ritonavir, ivermectin, tocilizumab, convalescent sera. </em></p>

Toward Cloud Federation

2012 ◽  
pp. 1-17 ◽  
Author(s):  
Antonio Celesti ◽  
Francesco Tusa ◽  
Massimo Villari
Keyword(s):  
Cloud Computing ◽  
Scientific Community ◽  
Early Stage ◽  
The Internet ◽  
The World ◽  
Cloud Federation ◽  
The Future ◽  
Future Challenges

Federation in cloud computing is an emerging topic. Currently, all over the world in both academia and industry contexts many operators are picking up the advantages of cloud computing and federation in planning the Internet of the future. Nevertheless, cloud federation is at the early stage, and the scientific community is not fully aware how the federation will impact the cloud computing scenario. In this chapter, the authors try to clarify the ideas and discuss the main future challenges regarding cloud federation.

scholarly journals THE THEME OF MEMORY IN CARYL CHURCHILL’S “FAR AWAY” AND “ESCAPED ALONE”

2018 ◽  
Vol 7 (46) ◽  
Keyword(s):  
Key Words ◽  
Negative Direction ◽  
Caryl Churchill ◽  
Political Events ◽  
The World ◽  
The Future ◽  
Dual Relationship ◽  
Theatre Theory ◽  
The Mind

From the 1990s onwards in particular, much significance has been given to theatre that is themed around the dual relationship between the mind and exposing the hidden memory, or re-animating what has been erased from memory. The aim of this paper is to uncover and defend the existence and future existence of a dystopic world in terms of how the mind relates it with reality in two post-modern plays, Escaped Alone (2016) and Far Away (2000), by one of British theatre’s most prominent of playwrights Caryl Churchill. Churchill, who is familiar negative direction that the world within which she lives is going, makes mention of a world that is leaning towards an unpredictable chaos by putting violence, death, and political events at the forefront. Within the frame of Jeanette Malkin’s Memoy-Theatre theory, the notion of the hidden memory emerges as Churchill uses the art of over-representation. In Far Away, how memory is changed and re-created as well when and how it affects the persona is emphasized through the use of three characters. Escaped Alone, which is about four women in their 70s who are reminiscing while gathered around in a backyard, the concept of time mangled into a state of complexity, bits and pieces of memories merge together, and global mayhem is projected before people’s eyes. Savagery and barbarianism are at the helm of each of these two plays. Churchill paints the future with a bleak sense of hopelessness and leaves her works open-ended. Key Words: Churchill, Far Away, Escaped Alone, Postmodern Theater, Memory

Conclusion

2018 ◽  
pp. 247-260
Author(s):  
Irus Braverman
Keyword(s):  
Scientific Community ◽  
Existential Crisis ◽  
The World ◽  
The Future

Conservation is the art of cultivating—here, that means cultivating both corals and hope for the future. The book’s conclusion begins with a description of two art-science collaborations and then moves to review the main themes of the book. It highlights that alongside the story of correlation, complexity, and wonder, Coral Whisperers has also told another story: a story about the polarized state of the scientific community that studies corals. Coral scientists from around the world emerge here not only as harbingers of doom and as messengers of hope but also, perhaps more importantly, as humans facing an existential crisis. The conclusion ends with a discussion of the 2017 documentary Chasing Coral, emphasizing that the journey from ephemeral optimism that can’t besustained to deeper iterations of hope that emerge on the brink of despair and exasperation requires a leap of faith. In the midst of their enormous pain and loss, coral scientists emerge to guide conservationists—and us all—through the perils of the Anthropocene.

Development and Challenges of HER2 Inhibitors Discovery

2020 ◽  
Vol 20 ◽  
Author(s):  
Zhi-Gang Sun ◽  
Liang-Hui Zhao ◽  
Zhi-Na Li ◽  
Hai-Liang Zhu
Keyword(s):  
Clinical Research ◽  
Small Molecule ◽  
Small Molecule Inhibitors ◽  
Cancer Drugs ◽  
Design Synthesis ◽  
Inhibitor Development ◽  
Her Family ◽  
The World ◽  
The Future

: The treatment of cancer has always been a major problem in the world. Some cancers cannot be treated with surgery, but only with cancer drugs. Among many cancer drugs, small molecule inhibitors play an irreplaceable role. HER2 is one of the HER family, and the development of HER2 inhibitors has made a huge contribution to the treatment of cancer. Some HER2 inhibitors are already on the market, and some HER2 inhibitors are undergoing clinical research. The design, synthesis and development of new HER2 inhibitors targeting different targets are also ongoing, and some are even applying for clinical research. The HER2 inhibitors that are on the market have developed resistance, which brings great challenges to the HER2 inhibitor development in the future. This article reviews the development and challenges of HER2 inhibitors discovery.

scholarly journals Foreign Practices in Land Cadaster Systems: An Experience for Ukraine

2020 ◽  
Vol 9 (2) ◽  
pp. 325-337
Author(s):  
Daria Kondratenko ◽  
Olena Savchuk ◽  
Anna Liubchych
Keyword(s):  
Key Words ◽  
Social Relations ◽  
The State ◽  
Land Resources ◽  
Legal Nature ◽  
The World ◽  
The Future ◽  
Land Relations

The experience of European organizations managing land cadaster system is analyzed with examples of land relations development given for different spheres: legal, technical, and economic. The peculiarities in adoption and application of the 3D land cadasters by different countries of the world is viewed. It is stated that a cadaster of the future is to be a multi-purpose one in the 3D or 4D format.   The need in modernizing current land legislation to improve the procedures of collecting, preserving, restoring, and utilizing land resources in Ukraine pertaining to implementation of the principle of the State land cadaster keeping is accentuated on. Advantages of account-and-registration systems are analyzed; the legal nature of social relations arising in this sphere is clarified. Recommendations concerning establishing the 3D cadaster in Ukraine are offered. Key words: lands account, cadaster systems, land, land parcels, the 3D cadaster.

Birth Journey of a Newborn: Transition from Intrauterine to Extrauterine Life

2017 ◽  
pp. 01-06
Author(s):  
Ruveyde Aydin
Keyword(s):  
Psychiatric Disorders ◽  
Key Words ◽  
Adult Life ◽  
Google Scholar ◽  
Intrauterine Life ◽  
Brain Waves ◽  
The World ◽  
The Future ◽  
Turkish Language ◽  
Delivery Rooms

The process of birth is an important factor that determines the kind of a person one will be in the future and how we see the world. This study examines the psychological experiences of newborns from the intrauterine to the extrauterine world. The study used English–Turkish language papers and was conducted in PubMed, Scopus, Cochrane and Google Scholar, using a combination of key words like ‘transtation extrauterine world’, ‘newborn’, ‘newborn psychology’, ‘birth and newborn’. During birth, babies undergo a lot of stress. Foetuses and babies can react to signals from their environment. Newborns listen intently to their mothers and prefer to hear those heard weeks before birth. Infants are also great dreamers, according to studies of brain waves. The newborn trauma at birth affects adult life and plays a role in many psychiatric disorders. So delivery rooms should be quieter places with dim lighting and even soft music. Keywords: Newborn, transtation, extrauterine, intrauterine life, psychology.

scholarly journals Twelve Symbolic Objects of Tangible/Intangible Culture

Res Mobilis ◽  
2020 ◽  
Vol 9 (11) ◽  
pp. 46-64
Author(s):  
Juan Fernando De Laiglesia González
Keyword(s):  
Cultural Heritage ◽  
Key Words ◽  
Language Use ◽  
Research Question ◽  
Intangible Cultural Heritage ◽  
The Past ◽  
The World ◽  
The Future ◽  
Tangible Culture

Design as Cultural Heritage is a 2018 European proposal; this draws on Tangible and Intangible Cultural Heritage regarded as ‘our heritage: where the past meets the future’. This paper aims to answer the research question about the nature of the space between the human been and the world. Therefore, it will analyse certain processes that occur in their thickness, focussing on ‘authenticity criteria’ employed by UNESCO to define tangible culture in order to identify different language use of ‘culture’. From these, both criteria and usage, this paper evaluate the four main reasons multidisciplinary background to support the late correlation between ‘tangible and intangible culture’. Eventually, this paper proposes four sequences of symbolic objects which embody tangible culture contents. Key Words: Culture, Tangible, Intangible, Authenticity.

Becoming Politicized

2017 ◽  
Vol 225 (4) ◽  
pp. 324-335 ◽  
Author(s):  
Dimitrios Barkas ◽  
Xenia Chryssochoou
Keyword(s):  
Collective Identity ◽  
Political Socialization ◽  
Greek Society ◽  
Economic Vulnerability ◽  
The World ◽  
The Future ◽  
Identity Model ◽  
Beliefs About The Future ◽  
Of Greece ◽  
The Way

Abstract. This research took place just after the end of the protests following the killing of a 16-year-old boy by a policeman in Greece in December 2008. Participants (N = 224) were 16-year-olds in different schools in Attiki. Informed by the Politicized Collective Identity Model ( Simon & Klandermans, 2001 ), a questionnaire measuring grievances, adversarial attributions, emotions, vulnerability, identifications with students and activists, and questions about justice and Greek society in the future, as well as about youngsters’ participation in different actions, was completed. Four profiles of the participants emerged from a cluster analysis using representations of the conflict, emotions, and identifications with activists and students. These profiles differed on beliefs about the future of Greece, participants’ economic vulnerability, and forms of participation. Importantly, the clusters corresponded to students from schools of different socioeconomic areas. The results indicate that the way young people interpret the events and the context, their levels of identification, and the way they represent society are important factors of their political socialization that impacts on their forms of participation. Political socialization seems to be related to youngsters’ position in society which probably constitutes an important anchoring point of their interpretation of the world.

Two Years after the Crisis: Do Risks of the Second Wave Become Stronger?

2011 ◽  
pp. 4-20
Author(s):  
M. Ershov
Keyword(s):  
High Risk ◽  
World Economy ◽  
External Shocks ◽  
Global Imbalances ◽  
Russian Economy ◽  
The World ◽  
The Future ◽  
Second Wave

With signs of normalization seemingly in place in the world economy, a number of problems show the possibility of aggravation in the future. The volume of derivatives in American banks grows significantly, high risk instruments are back in place and their use becomes more active, global imbalances increase. All of the above requires thorough approaches when creating mechanisms which can neutralize external shocks for the Russian economy and make it possible to develop in the new post-crisis environment.

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