Improvement in Behavioral Problems in Children with Intractable Epilepsy Using the Child Behavior Checklist after Surgical Intervention

Abstract The U.S. National Institute of Mental Health (NIMH) introduced the research domain criteria (RDoC) initiative to promote the integration of information across multiple units of analysis (i.e., brain circuits, physiology, behavior, self-reports) to better understand the basic dimensions of behavior and cognitive functioning underlying normal and abnormal mental conditions. Along those lines, this study examined the association between peripheral blood gene expression levels and emotional and behavioral problems in school-age children. Children were chosen from two age- and sex-matched groups: those with or without parental reports of any prior or current psychiatric diagnosis. RNA-sequencing was performed on whole blood from 96 probands aged 6–12 years who were medication-free at the time of assessment. Module eigengenes were derived using weighted gene co-expression network analysis (WGCNA). Associations were tested between module eigengene expression levels and eight syndrome scales from parent ratings on the Child Behavior Checklist (CBCL). Nine out of the 36 modules were significantly associated with at least one syndrome scale measured by the CBCL (i.e., aggression, social problems, attention problems, and/or thought problems) after accounting for covariates and correcting for multiple testing. Our study demonstrates that variation in peripheral blood gene expression relates to emotional and behavioral profiles in children. If replicated and validated, our results may help in identifying problem or at-risk behavior in pediatric populations, and in elucidating the biological pathways that modulate complex human behavior.

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Neurocognitive Outcomes and Their Diffusion Tensor Imaging Correlates in Children With Mild Traumatic Brain Injury

Journal of Child Neurology ◽

10.1177/0883073821996095 ◽

2021 ◽

pp. 088307382199609

Author(s):

Priyanka Madaan ◽

Deepak Gupta ◽

Deepak Agrawal ◽

Atin Kumar ◽

Prashant Jauhari ◽

...

Keyword(s):

Traumatic Brain Injury ◽

Diffusion Tensor Imaging ◽

Brain Injury ◽

Child Behavior ◽

Mild Traumatic Brain Injury ◽

Behavioral Problems ◽

Child Behavior Checklist ◽

Diffusion Tensor ◽

Sleep Habits ◽

Neurocognitive Outcomes

This study aimed to assess the neurocognitive outcomes and their diffusion tensor imaging correlates in children (aged 6-16 years) with mild traumatic brain injury. This prospective analysis included 74 children with mild traumatic brain injury (52 boys; mean age: 9.5 [±2.7] years). Wechsler Intelligence Scale for Children–Indian adaptation (WISC-IV), Child Behavior Checklist, and Children’s Sleep Habits Questionnaire were administered for 57 cases (at 3 months postinjury) and 51 controls of similar age. The findings of diffusion tensor imaging (done within 7 days of injury) were correlated with various WISC-IV indices. The presenting features at the time of injury were loss of consciousness (53%), confusion or disorientation (47%), and post-traumatic amnesia (10%). Other features in the acute phase included drowsiness (86%), headache (78%), balance problems (62%), nausea (47%), fatigue (45%), vomiting (35%), nasal or ear bleed (12%), sensitivity to sound and light (12%), etc. At 3 months postinjury, the children with mild traumatic brain injury performed poorly in terms of Intelligence Quotient, perceptual reasoning index, and processing speed index as compared to controls. Based on the Child Behavior Checklist, 17% of children with mild traumatic brain injury had internalizing behavioral problems in comparison with 4% of controls. Prevalence of poor sleepers in the mild traumatic brain injury cohort and controls was 12.3% and 2% respectively. Headache, reduced attention span, and fatigue were common postconcussion symptoms. There was a positive correlation between right uncinate fasciculus fractional anisotropy and verbal comprehension index ( r = 0.32; P < .05).

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Relationship between symptoms of insomnia in children and behavioral problems assessed by the Child Behavior Checklist (CBCL)

Psychologica ◽

10.14195/1647-8606_57_1_5 ◽

2014 ◽

Vol 1 (57) ◽

pp. 75-92

Author(s):

Edwiges Ferreira de Mattos Silvares ◽

Renatha El Rafihi‑Ferreira ◽

Maria Laura Nogueira Pires

Keyword(s):

Child Behavior ◽

Behavioral Problems ◽

Child Behavior Checklist

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The Effects of an Infant Formula Enriched with Milk Fat Globule Membrane, Long-Chain Polyunsaturated Fatty Acids and Synbiotics on Child Behavior up to 2.5 Years Old: The COGNIS Study

Nutrients ◽

10.3390/nu12123825 ◽

2020 ◽

Vol 12 (12) ◽

pp. 3825

Author(s):

Ana Nieto-Ruiz ◽

Estefanía Diéguez ◽

Natalia Sepúlveda-Valbuena ◽

Florian Herrmann ◽

Tomás Cerdó ◽

...

Keyword(s):

Child Behavior ◽

Infant Formula ◽

Behavioral Problems ◽

Educational Level ◽

Milk Fat ◽

Child Behavior Checklist ◽

Reference Group ◽

Long Term Effects ◽

Beneficial Effects ◽

Milk Fat Globule

Although early life nutrition influences brain development and mental health, the long-term effects of supplemented infant formula on children´s behavior remain unclear. We analyzed the effects of a bioactive nutrients-enriched-infant formula on children’s behavior up to 2.5 years, compared to a standard infant formula or breastfeeding. Current analysis involved 70 children who were fed a standard infant formula (SF, n = 29) or a bioactive compounds enriched-infant formula (EF, n = 41), during their first 18 months of life, and 33 breastfed (BF) children (reference group) participating in the COGNIS study. Behavioral problems were evaluated using the Child Behavior Checklist at 18 months and 2.5 years. Different statistical analyses were performed using SPSS. EF children aged 2.5 years presented fewer pathological affective problems than SF children. Besides, SF children were classified more frequently as bordering on internalizing problems than BF children. Rates of externalizing problems were increased in SF infants compared to EF and BF infants. Higher maternal IQ was found to have beneficial effects on internalizing and total problem rate in their offspring at 18 months of life; finally, higher maternal educational level was related with fewer ADHD problems in children at 18 months, as well as internalizing, externalizing, total and anxiety problems in children aged 2.5 years. Our analysis suggests that enriched infant formula fed infants seem to show fewer behavioral problems up to 2.5 years compared to a standard infant formula-fed infants. In addition to type of early feeding, maternal IQ and educational level seem to play a key role on children behavioral development.

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Sociodemographic Characteristics, Behavioral Problems, Parental Concerns and Children’s Strengths Reported by Parents

Paidéia (Ribeirão Preto) ◽

10.1590/1982-43272767201706 ◽

2017 ◽

Vol 27 (67) ◽

pp. 46-55 ◽

Cited By ~ 2

Author(s):

Deisy Ribas Emerich ◽

Luiz Renato Rodrigues Carreiro ◽

Ana Maria Justo ◽

Paula Guedes ◽

Maria Cristina Triguero Veloz Teixeira

Keyword(s):

Public Schools ◽

Behavior Problems ◽

Child Behavior ◽

Behavioral Problems ◽

Private School ◽

Child Behavior Checklist ◽

Adaptive Functioning ◽

Sociodemographic Factors ◽

Parental Concerns ◽

Parent Concerns

Abstract: Parental report is essential to understand adaptive difficulties in childhood. The aim of the study was to identify concerns of parents and qualities of children reported by parents, as well as the association of these variables with sociodemographic factors and child behavior problems. Parents of 353 schoolchildren from three public schools and one private school took part in the study. Assessment of behavior problems and parental reports about concerns and children’s strengths were obtained from the Child Behavior Checklist - CBCL. We submitted parents’ answers to the open-ended questions in the CBCL to a lexical analysis with the IRAMUTEQ software. Results concerning ‘strengths’ were related to affective and social interaction, while ‘concerns’ were related to academic performance and prevention of behavior problems. We concluded that parent concerns are targets of preventive interventions in childhood, while child strengths reported by parents are skills that need to be developed, as they help in adaptive functioning.

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A Pilot Investigation of a Novel Intervention to Improve Behavioral Well-Being for Children in Foster Care

Journal of Emotional and Behavioral Disorders ◽

10.1177/1063426617733715 ◽

2017 ◽

Vol 27 (1) ◽

pp. 3-13 ◽

Cited By ~ 3

Author(s):

Joanne N. Wood ◽

Susan L. Dougherty ◽

Jin Long ◽

Erica P. Messer ◽

David Rubin

Keyword(s):

Foster Care ◽

Child Behavior ◽

Behavioral Problems ◽

Child Behavior Checklist ◽

Well Being ◽

Care Group ◽

Historical Comparison ◽

Children In Foster Care ◽

Child Behavioral Problems

Many studies have established a link between foster care placement instability and child behavioral problems. Evidence-based interventions for behavioral problems, however, are often unavailable to children in foster care given challenges of recruiting behavioral health providers, sustaining funding, and engaging families in intensive interventions. This pilot study, therefore, sought preliminary data on the effectiveness of a novel brief intervention, Child–Adult Relationship Enhancement (CARE), to decrease behavioral problems in children entering foster care. CARE, a trauma-informed 6-hr training, was implemented at two foster care agencies. Nineteen children, aged 3 to 8 years, newly entering foster care whose caregivers were exposed to CARE were compared with 28 historical comparison children from the same foster care agencies. Child behavioral problems were assessed at baseline and follow-up using the Child Behavior Checklist (CBCL). Adjusted CBCL change scores revealed greater improvements in externalizing and internalizing behaviors from baseline to follow-up among children in the CARE group compared with the historical comparison group (all ps ≤ .05). The effect was concentrated in younger children. Thus, CARE showed promise in improving parent-reported child behavior problems. The effectiveness of CARE needs to be further evaluated as it is replicated within child welfare systems.

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The Child Behavior Checklist—Obsessive-Compulsive Subscale Detects Severe Psychopathology and Behavioral Problems Among School-Aged Children

Journal of Child and Adolescent Psychopharmacology ◽

10.1089/cap.2016.0125 ◽

2017 ◽

Vol 27 (4) ◽

pp. 342-348 ◽

Cited By ~ 2

Author(s):

Laura O. Saad ◽

Maria C. do Rosario ◽

Raony C. Cesar ◽

Marcelo C. Batistuzzo ◽

Marcelo Q. Hoexter ◽

...

Keyword(s):

Child Behavior ◽

Behavioral Problems ◽

Child Behavior Checklist ◽

Obsessive Compulsive ◽

School Aged Children ◽

Severe Psychopathology

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Temperament and Behavioral Problems of Preschool Children with Headache - A Controlled Study

The Spanish Journal of Psychology ◽

10.1017/sjp.2013.11 ◽

2013 ◽

Vol 16 ◽

Cited By ~ 2

Author(s):

Luciana Leonetti Correia ◽

Maria Beatriz Martins Linhares

Keyword(s):

Negative Affect ◽

Child Behavior ◽

Behavioral Problems ◽

Child Behavior Checklist ◽

Community Sample ◽

Emotional And Behavioral Problems ◽

Controlled Study ◽

Control Group ◽

Sensory Qualities ◽

Preschool Aged Children

AbstractThe purpose of this study was to compare differences in temperament and emotional and behavioral problems in a community sample of young children who experience headaches to those without such complaints. The whole sample was comprised 75 non-referred, preschool-aged children (3–5 years old), including 22 with headache complaints and 53 without headaches (control group). The children’s headache symptoms were assessed with a questionnaire that was given to the mothers. Rothbart’s Children’s Behavior Questionnaire was used to assess temperament, and the Child Behavior Checklist 1 ½–5 was used to assess emotional and behavioral problems. Compared with the control group, children with headache complaints showed more discomfort, which is the amount of negative affect induced by the sensory qualities of stimulation, including intensity, rate, or complexity of light, movement, sound, texture, or a combination of these modes of stimuli. These children also had higher scores for externalizing and internalizing emotional and behavioral problems compared to children without headaches. These findings show that the preschool-aged children with headaches presented more emotional and behavioral problems than the control group.

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