Ứng dụng nội soi dải ánh sáng hẹp kết hợp nội soi vi phẫu bằng laser CO2 trong chẩn đoán và điều trị ung thư hạ họng, thanh quản giai đoạn sớm

2021 ◽  
Author(s):  
Phuong Nam Tran
Keyword(s):  
Co2 Laser ◽  
Laryngeal Carcinoma ◽  
Narrow Band ◽  
Narrow Band Imaging ◽  
Early Stage ◽  
Anterior Commissure ◽  
Tumor Control ◽  
Post Surgery ◽  
Endoscopic Microsurgery ◽  
Type V

TÓM TẮT Mục tiêu: Đánh giá kết quả ứng dụng nội soi dải ánh sáng hẹp kết hợp nội soi vi phẫu bằng Laser CO2 trong chẩn đoán và điều trị ung thư hạ họng và ung thư thanh quản giai đoạn sớm. Phương pháp nghiên cứu: Nghiên cứu tiến cứu, có can thiệp lâm sàng trên 18 bệnh nhân ung thư hạ họng, ung thư thanh quản ở giai đoạn sớm, được phát hiện tổn thương ác tính bằng nội soi dải ánh sáng hẹp, điều trị phẫu thuật nội soi vi phẫu bằng Laser CO2. Kết quả: Tuổi trung bình mắc bệnh là 63,8 ± 12,6; bệnh nhân có hút thuốc lá chiếm 61,1%; triệu chứng khàn tiếng chiếm 72%, ung thư giai đoạn T1a có tỷ lệ 72,2%; IPCL type V-1 là 72,2%; khả năng kiểm soát bờ rìa là 83,3%, không có tai biến trong phẫu thuật 17/18 trường hợp và di chứng sau phẫu thuật tháng thứ 1 là tăng sinh mô hạt (77,8%), tháng thứ 3 là dính mép trước dây thanh (27,8%). Kết luận: Nội soi dải ánh sáng hẹp có giá trị phát hiện sớm ung thư hạ họng, ung thư thanh quản. Phẫu thuật nội soi vi phẫu bằng Laser CO2 ung thư hạ họng, ung thư thanh quản ở giai đoạn sớm mang lại kết quả tốt, tỷ lệ tai biến và biến chứng sau phẫu thuật thấp, bảo tồn được tối đa chức năng phát âm, hô hấp và nuốt. ABSTRACT UTILITY OF NARROW - BAND IMAGING ENDOSCOPY COMBINED WITH CO2 LASER ENDOSCOPIC MICROSURGERY IN DIAGNOSIS AND TREATMENT OF EARLYSTAGE HYPOPHARYNGEAL AND LARYNGEAL CARCINOMA Objective: To evaluate the results of applying narrow band imaging endoscopy combined with CO2 laser endoscopic microsurgery to diagnose and treat early stage hypopharyngeal and laryngeal carcinoma. Methods: A prospective study was conducted on 18 patients with early stage hypopharyngeal and laryngeal carcinoma. Results: The mean age was 63.8 ± 12.6; smoker was 61.1%, the rate of hoarseness was 72%, T1a tumor stage was 72.2%, IPCL type V-1 was 72,2%, marginal tumor control was 83.3%. There were of 17/18 case with no complication during operation. The rate of extensive granuloma was 77.8% in the first month, and of anterior commissure adhesion was 27.8% in the third month post - surgery. Conclusion: Narrow band imaging endoscopy was a valuable tool in screening for early stage hypopharyngeal and laryngeal carcinoma. CO2 laser endoscopic microsurgery was an effective method. The rate of complication during and after surgery was low. This method restores the maximum function of speech, breathing and swallowing. Keywords: Early - stage pharyngeal cancer, early - stage laryngeal cancer, narrow - band imaging endoscopy, CO2 laser endoscopic microsurgery.

scholarly journals Outcome of Early-Stage Glottic Laryngeal Carcinoma Patients Treated with Radical Radiotherapy Using Different Techniques

2019 ◽  
Vol 2019 ◽  
pp. 1-9 ◽  
Author(s):  
Oguz Cetinayak ◽  
Ersoy Dogan ◽  
Ahmet Kuru ◽  
Nesrin Akturk ◽  
Barbaros Aydin ◽  
...  
Keyword(s):  
Local Control ◽  
Laryngeal Carcinoma ◽  
Early Stage ◽  
Anterior Commissure ◽  
Conventional Technique ◽  
Radical Radiotherapy ◽  
Treatment Techniques ◽  
Median Total Dose ◽  
Effective Treatment Modality ◽  
Laryngeal Carcinomas

Purpose. The aim was to evaluate the treatment outcomes and prognostic characteristics of patients with early-stage glottic laryngeal carcinoma who underwent radical radiotherapy (RT) with different techniques. Patients and Methods. Radiotherapy was applied using the 2D conventional technique between 1991 and 2004 (130 patients), 3DCRT until 2014 (125 patients), and by VMAT until January 2017 (44 patients). Clinical T stages were 38 (12.7%) for Tis, 209 (69.9%) for T1, and 52 (17.4%) for T2. Radiotherapy technique and energy, anterior commissure involvement, and stage were analyzed as prognostic factors. Results. The median total dose was 66 (50–70) Gy, and median follow-up time was 72 (3–288) months; 5-year disease-specific survival (DSS) rates were 95.8%, 95.5%, and 88.6%, respectively, in Tis, T1, and T2 stages. In multivariate analyses, anterior commissure involvement was found significant for all survival and local control rates. The patients treated with VMAT technique had better local control and DSS rates. However, these results were not statistically significant. Conclusion. In early-stage laryngeal carcinomas, radical RT is a function sparing and effective treatment modality, regardless of treatment techniques.

scholarly journals Uterine Cervical Neoplasm Diagnosed by Flexible Magnifying Endoscopy with Narrow Band Imaging

Diagnostics ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. 903
Author(s):  
Hideki Kobara ◽  
Kunihisa Uchita ◽  
Noriya Uedo ◽  
Noriko Matsuura ◽  
Noriko Nishiyama ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Pap Smear ◽  
Narrow Band ◽  
Narrow Band Imaging ◽  
Early Stage ◽  
Magnifying Endoscopy ◽  
Diagnostic Tools ◽  
Gastrointestinal Neoplasms ◽  
Cervical Neoplasm ◽  
Uterine Cervical Neoplasm

When detected early, uterine cervical cancer is one of the most successfully treatable forms of cancer. The diagnostic accuracy of the standard method, the Pap smear test followed by colposcopy, remains unsatisfactory. To improve detection of early-stage cervical cancer, new diagnostic tools for uterine cervical intraepithelial neoplasm (CIN) need to be developed. Magnifying endoscopy with narrow- band imaging (ME-NBI), which allows the visualization of the micro-structure as well as micro-vascularity of the mucosal surface, has excellent diagnostic ability for early gastrointestinal neoplasms. In our previous investigation, ME-NBI was efficacious for diagnosis of CIN. We herein report two notable cases of CIN3 that were diagnosed by ME-NBI that were not detected by colposcopy. These cases illustrate the usefulness of ME-NBI for diagnosis of early-stage uterine cervical neoplasms.

Endoscopic diagnosis of laryngeal cancer and precancerous lesions by narrow band imaging

2010 ◽  
Vol 125 (3) ◽  
pp. 288-296 ◽  
Author(s):  
X-G Ni ◽  
S He ◽  
Z-G Xu ◽  
L Gao ◽  
N Lu ◽  
...  
Keyword(s):  
Sensitivity And Specificity ◽  
Laryngeal Cancer ◽  
Narrow Band ◽  
Narrow Band Imaging ◽  
Precancerous Lesions ◽  
Type I ◽  
Severe Dysplasia ◽  
Laryngeal Lesions ◽  
Type V

AbstractObjective:To investigate the characteristics of the laryngeal mucosal microvascular network in suspected laryngeal cancer patients, using narrow band imaging, and to evaluate the value of narrow band imaging endoscopy in the early diagnosis of laryngeal precancerous and cancerous lesions.Patients and methods:Eighty-five consecutive patients with suspected precancerous or cancerous laryngeal lesions were enrolled in the study. Endoscopic narrow band imaging findings were classified into five types (I to V) according to the features of the mucosal intraepithelial papillary capillary loops assessed.Results:A total of 104 lesions (45 malignancies and 59 nonmalignancies) was detected under white light and narrow band imaging modes. The sensitivity and specificity of narrow band imaging in detecting malignant lesions were 88.9 and 93.2 per cent, respectively. The intraepithelial papillary capillary loop classification, as determined by narrow band imaging, was closely associated with the laryngeal lesions' histological findings. Type I to IV lesions were considered nonmalignant and type V lesions malignant. For type Va lesions, the sensitivity and specificity of narrow band imaging in detecting severe dysplasia or carcinoma in situ were 100 and 79.5 per cent, respectively. In patients with type Vb and Vc lesions, the sensitivity and specificity of narrow band imaging in detecting invasive carcinoma were 83.8 and 100 per cent, respectively.Conclusion:Narrow band imaging is a promising approach enabling in vivo differentiation of nonmalignant from malignant laryngeal lesions by evaluating the morphology of mucosal capillaries. These results suggest endoscopic narrow band imaging may be useful in the early detection of laryngeal cancer and precancerous lesions.

scholarly journals Role of narrow band imaging in the detection of mucosal lesions of head and neck

2020 ◽  
Vol 6 (9) ◽  
pp. 1678
Author(s):  
Pranay Bhandari ◽  
Kavita Sachdeva
Keyword(s):  
Early Detection ◽  
Head And Neck ◽  
Narrow Band ◽  
Narrow Band Imaging ◽  
Early Stage ◽  
Early Screening ◽  
White Light Endoscopy ◽  
Promising Tool ◽  
Mucosal Lesions

<p class="abstract"><strong>Background: </strong>Head and neck mucosal lesions are difficult to diagnose at early stage; therefore, they usually present at an advance phase. Narrow Band imaging (NBI) first came to use around 2005 and became one of the most used technologies for image enhanced endoscopy.</p><p class="abstract"><strong>Material and method: </strong>In order to identify best method for early detection of mucosal lesion of head and neck, we examined patients with suspected lesions first under white light endoscopy then under NBI endoscopy. Patients under-went biopsy thereafter, and results were compared. Our aim was to evaluate the role of NBI as a screening tool in the early detection of mucosal lesions of head and neck.</p><p class="abstract"><strong>Result:</strong> It was observed that NBI is useful tool in identifying mucosal lesions of head and neck early. 71 patients were included in our study and it was observed that NBI endoscopy shows 100% sensitivity, 96.36% specificity and 97.18% accuracy in identifying benign lesions. It shows 100% sensitivity, 94.74% specificity and 98.59% accuracy in identifying malignant lesions.</p><p class="abstract"><strong>Conclusion:</strong> In our study we came to conclusion that NBI is very promising tool for early screening purposes of mucosal lesions of head and neck which were missed in routine examination.</p>

Combined use of a magnifying endoscope with a narrow band imaging system and a multibending endoscope for en bloc EMR of early stage gastric cancer

2004 ◽  
Vol 60 (1) ◽  
pp. 79-84 ◽  
Author(s):  
Kazuki Sumiyama ◽  
Mitsuru Kaise ◽  
Takashi Nakayoshi ◽  
Masayuki Kato ◽  
Takahiro Mashiko ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Imaging System ◽  
Narrow Band ◽  
Narrow Band Imaging ◽  
Early Stage ◽  
En Bloc ◽  
Combined Use ◽  
Magnifying Endoscope

scholarly journals Leukoplakia: An Invasive Cancer Hidden within the Vocal Folds. A Multivariate Analysis of Risk Factors

2021 ◽  
Vol 11 ◽  
Author(s):  
Hanna Klimza ◽  
Wioletta Pietruszewska ◽  
Oskar Rosiak ◽  
Joanna Morawska ◽  
Piotr Nogal ◽  
...  
Keyword(s):  
Risk Factors ◽  
White Light ◽  
Narrow Band ◽  
Narrow Band Imaging ◽  
Anterior Commissure ◽  
Wide Spectrum ◽  
Vocal Folds ◽  
Invasive Cancer ◽  
Diagnostic Tools ◽  
Final Histology

IntroductionDiscerning the preoperative nature of vocal fold leukoplakia (VFL) with a substantial degree of certainty is fundamental, seeing that the histological diagnosis of VFL includes a wide spectrum of pathology and there is no consensus on an appropriate treatment strategy or frequency of surveillance. The goal of our study was to establish a clear schedule of the diagnostics and decision-making in which the timing and necessity of surgical intervention are crucial to not miss this cancer hidden underneath the white plaque.Material and MethodsWe define a schedule as a combination of procedures (white light and Narrow Band Imaging diagnostic tools), methods of evaluating the results (a combination of multiple image classifications in white light and Narrow Band Imaging), and taking into account patient-related risk factors, precise lesion location, and morphology. A total number of 259 patients with 296 vocal folds affected by leukoplakia were enrolled in the study. All patients were assessed for three classifications, in detail according to Ni 2019 and ELS 2015 for Narrow Band Imaging and according to Chen 2019 for white light. In 41 of the 296 folds (13.9%), the VFL specimens in the final histology revealed invasive cancer. We compared the results from the classifications to the final histology results.ResultsThe results showed that the classifications and evaluations of the involvement of anterior commissure improve the clinical utility of these classifications and showed improved diagnostic performance. The AUC of this model was the highest (0.973) with the highest sensitivity, specificity, PPV, and NPV (90.2%, 89%, 56.9%, and 98.3%, respectively).ConclusionThe schedule that combines white light and Narrow Band Imaging, with a combination of the two classifications, improves the specificity and predictive value, especially of anterior commissure involvement.

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