scholarly journals Exfoliative dermatitis due to dermatophytosis

2021 ◽  
Vol 15 (02) ◽  
pp. 306-309
Author(s):  
Risa Miliawati Nurul Hidayah ◽  
Andini Dwikenia Anjani ◽  
Lies Marlysa Ramali ◽  
Oki Suwarsa ◽  
Hendra Gunawan

Exfoliative dermatitis (ED) or erythroderma is defined as diffuse erythema and scaling of the skin involving more than 90% of the total body skin surface, which can be caused by variety of systemic and cutaneous diseases, such as infection, including dermatophytosis. Dermatophytosis is a superficial fungal infection of keratinized tissue caused by dermatophytes. There are only few case reports of ED due to dermatophytosis in literature. A 39-year-old male present with history of diffuse erythematous macules and scales almost on entire body due to dermatophytosis was reported. The diagnosis of dermatophytosis was confirmed by direct microscopic examination, fungal culture, and histopathological examination. Patient was treated with 2% ketoconazole shampoo and two pulses of 1-week of 200 mg itraconazole twice a day for each month. Clinical improvement was showed on the 7th day of observation characterized by decreasing of erythematous macules and scales. Mycological and clinical improvements were obtained on the 29th day of observation. The etiology of ED should be determined in order to give an appropiate treatment.

2020 ◽  
Vol 11 ◽  
pp. 268
Author(s):  
Andrew Aranha ◽  
Pankaj Kumar ◽  
Ajay Choudhary ◽  
Purnima Paliwal

Background: Spinal dermoid cysts are benign tumors that result from congenital or acquired ectodermal inclusions. Long segment intramedullary involvement of the spinal cord is exceedingly rare, and there are only a handful of case reports found in the literature. Case Description: A 30-year-old female presented with a 3-month history of myelopathy characterized by progressive quadriparesis and urinary incontinence. Magnetic resonance imaging revealed multifocal heterogeneous intramedullary masses extending from C2 to T4 and at T12–L1 with similar intensity lesions seen within the central cord from T5 to T11 level. Following tumor decompression, she showed significant improvement in neurological function 1 month later. The histopathological examination confirmed the diagnosis of a multifocal intramedullary dermoid cyst. Conclusion: Partial surgical extirpation is a reasonable treatment for long segment intramedullary dermoid cysts, particularly when the tumor capsule is adherent to critical adjacent neural tissues.


2014 ◽  
Vol 2014 ◽  
pp. 1-2 ◽  
Author(s):  
Luca Bonanni ◽  
Michele Dalla Vestra ◽  
Andrea Zancanaro ◽  
Fabio Presotto

We describe the case of 79-year-old man admitted to our general hospital for a 6-week history of progressive dysphagia to solids and liquids associated with weight loss. To reach a diagnosis a total body CT scan with low-osmolality iodinate contrast agent was performed. Two hours later the patient developed an acute respiratory failure requiring orotracheal intubation and mechanical ventilation. The laboratory and neurological tests allow formulating the diagnosis of myasthenia gravis. In literature, other three case reports have associated myasthenic crisis with exposure to low-osmolality contrast media. This suggests being careful in administering low-osmolality contrast media in myasthenic patients.


2021 ◽  
Vol 9 (5) ◽  
pp. 1131-1135
Author(s):  
Prasanna N Mogasale ◽  
Radhika. C ◽  
Nagaraj S

Erythroderma also known as generalized Exfoliative dermatitis which refers to a scaling involving 90% or more of the cutaneous surface. Clinicians are challenged to find the cause of exfoliative dermatitis by eliciting history of illness prior to erythema. Patients presenting acutely with exfoliative dermatitis often require admission because their total body functions can require monitoring. In western medicine, the principle management is to maintain skin moisture, avoid scratching, apply topical steroids; prolonged glucocorticoids therapy often is needed. From Ayurvedic perspective it could be correlated to Eka Kusta. Eka Kusta is the Vata Kapha Pradhana Vikara. Where skin lesions are Mahavastu, Masthyashaklopamam, Krisha Aruna in Varna. Here presenting a case of 48 years old female with erythroderma who was on long- term steroidal therapy. Treatment was planned with Shamana line of management based on her Bala. The treatment is carried out for one and half month in OPD and IPD section, all the western medicine was stopped and there was total remission of symptoms with Shamana Aushadhis. Keywords: Erythroderma, Eka Kusta, Shamana Aushadhis


2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Mingrui Zhang ◽  
Lanxiang Jiang ◽  
Fuqiu Li ◽  
Yangchun Xu ◽  
Sha Lv ◽  
...  

Abstract Background Dermatophytosis is a fungal infectious disease caused by dermatophytes, which produce protease and keratinase to digest keratin, leading to the colonization, invasion, and infection of the stratum corneum of the skin, hair shafts, and nails. Trichophyton interdigitale belongs to Trichophyton mentagrophytes complex, which is the common pathogen causing dermatophytosis. Fungal keratitis, also called keratomycosis, is an infectious disease of cornea. Case presentation Here, we report a case of simultaneous dermatophytosis and keratomycosis caused by Trichophyton interdigitale. A 67-year-old man presented with extensive erythema all over the body since 4 years ago, fungal infection of left eye for 2 years, and loss of vision in the eye. These symptoms had become aggravated in the last month. Dermatological examinations showed extensive erythematous plaques with clear borders and scales, scattered red papules with ulceration, and scabs throughout the body. Onychomycosis was observed on the nails of left hand, conjunctival infection with secretion and loss of vision were noted in left eye. Hyaline septate hyphae were observed under direct microscopic examination, fungal culture and internal transcribed spacer sequencing revealed T. interdigitale. Histopathological examination suggested infectious granuloma. A diagnosis of dermatophytosis and keratomycosis caused by T. interdigitale with loss of vision in left eye was made. The patient was treated with luliconazole cream (two applications per day) and itraconazole (100 mg, BID, PO). Complete clinical remission was achieved after 1 month. Subsequently, the patient underwent left eye enucleation in the ophthalmology department. Conclusions In the present study, we reported a case of simultaneous dermatophytosis and keratomycosis caused by T. interdigitale, and reviewed the literature on corneal infection caused by Trichophyton. A total of 10 articles with 45 patients were published between 1973 and 2018. The pathogen of 27 patient were identified to species level. There were T. schoenleinii (17), T. mentagrophytes (4), T. verrucosum (3), T. rubrum (1), T. erinacei (1), and T. interdigitale (1). Five patients had corneal trauma, one had contact lens use history. Direct microscopic examination, fungal culture, and analysis of physiological characteristics were the main methods of identification. Early diagnosis and prompt treatment may help improve the management and outcomes.


2003 ◽  
Vol 39 (6) ◽  
pp. 543-546 ◽  
Author(s):  
Edmund J. Rosser

A cat was presented for a 2-year history of a recurrent, soft-tissue swelling of the left metacarpal region. The mass was excised and submitted for aerobic and anaerobic bacterial culture, fungal culture, and histopathological examination. Cultures revealed the organism Paecilomyces lilacinus, and histopathological examination showed a nodular mycotic granuloma. Itraconazole (10 mg/kg body weight, per os [PO], q 24 hours) was administered and continued for a total of 60 days, with a swelling of the upper lip occurring 3 months after the initial presentation. Subsequent surgical excisions and debridements along with treatment with itraconazole (20 mg/kg body weight, PO, q 24 hours) for a total of 4 months were curative.


Blood ◽  
1959 ◽  
Vol 14 (1) ◽  
pp. 1-23 ◽  
Author(s):  
E. DONNALL THOMAS ◽  
HARRY L. LOCHTE ◽  
JOSEPH W. FERREBEE

Abstract Case reports of 5 patients with acute leukemia receiving total-body irradiation and intravenous infusion of normal marrow are presented. An eight-month follow-up on a previously reported patient with chronic leukemia is included and a review of an individual receiving nitrogen mustard and marrow is presented for comment. Of several patients reported in this and in a previous communication only two may be said to have obtained significant clinical benefit. Potential reasons for this incidence of improvement are advanced and the general subject of total-body irradiation and marrow replacement in man is discussed. Pitfalls and problems biologic and physical and the theory of their circumvention are analyzed.


2017 ◽  
Vol 7 (1) ◽  
pp. 27-30
Author(s):  
Kamalika P Roy ◽  
Dhruba J Datta ◽  
Srikanth Madam ◽  
Praneeth K Koduru

ABSTRACT Aim To investigate the changes in the vibratory function of the vocal cords in two diagnosed cases of tuberculosis during and after completion of treatment. Background Laryngeal tuberculosis is one of the most common granulomatous diseases of the larynx. Patients present with hoarseness, irritation in throat, dysphagia, and breathlessness. The hoarseness occurs due to the granulomatous reaction involving the subepithelial layer of the vocal cords, which heal with fibrosis. Case reports A 56-year-old male presented with a 2-month history of cough, hoarseness allegedly precipitated by vocal abuse, dysphagia, weight loss, and evening rise of temperature. There was associated history of tobacco and betel nut intake. A 50-year-old female patient presented with complaints of hoarseness of 3 months duration not associated with any cough, dysphagia, fever, weight loss, or breathlessness. Clinical examination showed whitish lesions in the vocal cords. Microlaryngeal surgery done in both cases for collecting biopsy specimen showed a chronic inflammatory process with granuloma. Antitubercular treatment consisting of Isoniazid, Rifampicin, Pyrazinamide, and Ethambutol was given for a period of 6 months. The patients were assessed at the end of 2 and 6 months of treatment symptomatically and clinically with fiber-optic laryngoscopy and stroboscopy. Significant improvement in the vibratory pattern of vocal cords and voice quality was noted in both the patients. Conclusion Early recognition of the disease and initiation of treatment are necessary for a desirable outcome of vibratory function of the vocal cords. Clinical significance As patients present with nonspecific symptoms, an accurate diagnosis of laryngeal tuberculosis can be made by a proper histopathological examination and acid-fast staining of specimen obtained by microlaryngeal surgery. Early initiation of treatment is the key to better outcome. How to cite this article Roy KP, Datta DJ, Madam S, Koduru PK. Tuberculosis of the Larynx: A Review of Two Cases. Int J Phonosurg Laryngol 2017;7(1):27-30.


2020 ◽  
Vol 31 (14) ◽  
pp. 1414-1419
Author(s):  
Alvaro Quincho-Lopez ◽  
Juan Montenegro-Idrogo ◽  
Rogger Oscar Verona-Rubio

Colonic cryptococcal infection is unusual in people living with HIV (PLWH) and even more so without concomitant neurological compromise. Published case reports describe diarrhea and other intestinal manifestations that are often confused with systemic tuberculosis infection. We describe an Peruvian woman living with HIV on antiretroviral therapy who presented hypotensive with a 6-month history of fever and epigastric pain, in addition to episodes of sporadic diarrhea. Due to the suspicion of systemic tuberculosis, antituberculosis treatment was started. Days later, without clinical improvement, colonoscopy revealed ulcers in the transverse colon. Histopathological examination of biopsied tissue was compatible with Cryptococcus spp. She received antifungal therapy with amphotericin B and fluconazole. Despite the treatment, the patient died six days later from multiple organ failure.


VASA ◽  
2011 ◽  
Vol 40 (3) ◽  
pp. 251-255 ◽  
Author(s):  
Gruber-Szydlo ◽  
Poreba ◽  
Belowska-Bien ◽  
Derkacz ◽  
Badowski ◽  
...  

Popliteal artery thrombosis may present as a complication of an osteochondroma located in the vicinity of the knee joint. This is a case report of a 26-year-old man with symptoms of the right lower extremity ischaemia without a previous history of vascular disease or trauma. Plain radiography, magnetic resonance angiography and Doppler ultrasonography documented the presence of an osteochondrous structure of the proximal tibial metaphysis, which displaced and compressed the popliteal artery, causing its occlusion due to intraluminal thrombosis..The patient was operated and histopathological examination confirmed the diagnosis of osteochondroma.


Author(s):  
Mohammad M. Al-Qattan ◽  
Nada G. AlQadri ◽  
Ghada AlHayaza

Abstract Introduction Herpetic whitlows in infants are rare. Previous authors only reported individual case reports. We present a case series of six infants. Materials and Methods This is a retrospective study of six cases of herpetic whitlows in infants seen by the senior author (MMA) over the past 23 years (1995–2017 inclusive). The following data were collected: age, sex, digit involved in the hand, mode of transmission, time of presentation to the author, clinical appearance, presence of secondary bacterial infection, presence of other lesions outside the hand, method of diagnosis, treatment, and outcome. Results All six infants initially presented with classic multiple vesicles of the digital pulp. In all cases, there was a history of active herpes labialis in the mother. Incision and drainage or deroofing of the vesicles (for diagnostic purposes) resulted in secondary bacterial infection. Conclusion The current report is the first series in the literature on herpetic whitlows in infants. We stress on the mode of transmission (from the mother) and establishing the diagnosis clinically. In these cases, no need for obtaining viral cultures or polymerase chain reaction; and no medications are required. Once the vesicles are disrupted, secondary bacterial infection is frequent and a combination of oral acyclovir and intravenous antibiotics will be required.


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