scholarly journals Prevalence and Anti-Microbial Susceptibility of Hospital Acquired Infections in Two Pediatric Intensive Care Units in Egypt

2019 ◽  
Vol 7 (11) ◽  
pp. 1744-1749 ◽  
Author(s):  
Sally El-Sahrigy ◽  
Mohamed G. Shouman ◽  
Hanan Ibrahim ◽  
Azza Abdel Rahman ◽  
Sonia Adolf Habib ◽  
...  
Keyword(s):  
Risk Factors ◽  
Intensive Care ◽  
Intensive Care Units ◽  
Respiratory Infections ◽  
Pediatric Intensive Care ◽  
Pediatric Intensive Care Units ◽  
Female Ratio ◽  
Gram Negative ◽  
Mortality And Morbidity ◽  
Hospital Acquired

BACKGROUND: Hospital-acquired (nosocomial) infection is a common serious health problem worldwide, especially in pediatric intensive care units and is associated with high mortality and morbidity, prolonged hospital stays and high cost.AIM: To determine the types of organisms involved in hospital-acquired an infection in two pediatric intensive care units during the one-year study and its anti-microbial susceptibility.MATERIAL AND METHODS: This study was carried out in the pediatric intensive care units (PICU) of Ain Shams & Cairo Universities, where 86 pediatric patients were recruited. Their age ranged from 1 month to 156 months with mean 20.7 ± 25.8 months. Male to female ratio was 37:29. Four samples were collected from each child for culture and sensitivity: blood, endotracheal aspirate, urine and skin swab.RESULTS: The most common microorganism was staphylococcus while Gram-negative bacteria were the commonest group. Amikacin and imipenem are the most sensitive antibiotics. Risk estimate for different risk factors among studied patients revealed no significance.CONCLUSION: Staphylococcus was the commonest micro-organism while Gram-negative infections were the commonest group among PICU with a predominance of Acinetobacter and Klebsiella. Respiratory infections were the most common, followed by blood-borne infection. Risk factors for mortality were not significant.

scholarly journals Risk factors for healthcare-associated infection in pediatric intensive care units: a systematic review

2009 ◽  
Vol 25 (suppl 3) ◽  
pp. S373-S391 ◽  
Author(s):  
Maria Júlia Gonçalves de Mello ◽  
Maria de Fátima Pessoa Militão de Albuquerque ◽  
Heloísa Ramos Lacerda ◽  
Wayner Vieira de Souza ◽  
Jailson B. Correia ◽  
...  
Keyword(s):  
Risk Factors ◽  
Systematic Review ◽  
Intensive Care ◽  
Tract Infection ◽  
Intensive Care Units ◽  
Pediatric Intensive Care ◽  
Healthcare Associated Infection ◽  
Pediatric Intensive Care Units ◽  
Healthcare Associated ◽  
Adequate Design

A systematic review of observational studies on risk factors for healthcare-associated infection in pediatric Intensive Care Units (ICU) was carried out. Studies indexed in MEDLINE, LILACS, Cochrane, BDENF, CAPES databases published in English, French, Spanish or Portuguese between 1987 and 2006 were included and cross references added. Key words for search were "cross infection" and "Pediatric Intensive Care Units" with others sub-terms included. 11 studies were selected from 419 originally found: four studies had healthcare-associated infection as the main outcome without a specific site; three articles identified factors associated with lower respiratory tract infection (pneumonia or tracheitis); three articles were concerned with laboratory-confirmed bloodstream infection; and a single retrospective study analyzed urinary tract infection. The production of evidence on risk factors Paediatric ICU has not kept up the same pace of that on adult - there are few studies with adequate design and statistical analysis. The methodological diversity of the studies did not allow for a summarized measurement of risk factors.

scholarly journals Incidence of emerging multidrug-resistant organisms and its impact on the outcome in the pediatric intensive care

2021 ◽  
Vol 69 (1) ◽  
Author(s):  
Ahmed R. Rezk ◽  
Somaia Abdelhammed Bawady ◽  
Nashwa Naguib Omar
Keyword(s):  
Risk Factors ◽  
Intensive Care ◽  
Intensive Care Units ◽  
Significant Risk ◽  
Pediatric Intensive Care ◽  
Multidrug Resistant ◽  
University Hospitals ◽  
Acinetobacter Species ◽  
Mortality And Morbidity ◽  
Multidrug Resistant Organisms

Abstract Background Healthcare-associated infections (HCAI) are a worldwide threat in intensive care units particularly in the pediatric intensive care units with a major cause of morbidity and mortality among this age group. The aim of the study is to determine the prevalence and risk factors predisposing to multidrug-resistant organisms (MDROs) infections among pediatric intensive care unit (PICU) patients at Ain Shams Pediatric University Hospitals as well as determining mortality and morbidity rates along with the length of stay at PICU. Results Culture results revealed that of the 282 patients evaluated, only 26 (9.2%) were MDROs (half of the affected patients had Acinetobacter species (50%) and the rest of them were free, 256 (90.8%). Our study revealed that the majority of MDROs were isolated from sputum in more than half of the patients 19/32 (59.3%) followed by whole blood in 10/32 (31.2%) and urine in 3/32 (9.4%). Pulmonary system was the most common affected site and was mainly colonized by MDR Acinetobacter (71.4%) followed by MDR Klebsiella (41.6%). Regarding MDR risk factors in our PICU, multivariate logistic regression analyses showed significant relationship between MDROs and age under 1 year (odds ratio [OR] 2.4554; 95% confidence interval [95% CI] (1.072–5.625); p = 0.043) and underlying pulmonary disease (OR 2.417; 95% CI (1.014–5.761); p = 0.592). A statistically significant higher mortality was detected in patients colonized with MDROs 9/26 (34.6%) versus MDROs non-colonized patients 32/256 (12.5%) [P=0.002]. Moreover, MDROs infection has negative significant risk with discharged patients ([OR] 0.269; [95% CI] (0.111–0.656); p = 0.002). Additionally, patients infected with MDROs did have significantly greater PICU stay than those non-infected [median (IQR), 16.5 (10.7–22), 5 (4–8), P=0.00] and have longer ventilation [median (IQR), 15.5 (10–18), 3 (2–10), P=0.00]. Conclusion Prevalence of MDROs (9.2%) was low among PICU cases at Ain Shams University Hospitals. Most common MDROs were Acinetobacter and Klebsiella followed by pseudomonas species. The frequency of gram-negative organisms is much more common than gram-positive organisms. An increasing rate of antimicrobial resistance with increasing mortality and morbidity among PICU patients is observed worldwide; even for new categories, so, strict infection control programs should be implemented.

scholarly journals Risk Factors and Characterization of Plasmodium Vivax-Associated Admissions to Pediatric Intensive Care Units in the Brazilian Amazon

PLoS ONE ◽  
2012 ◽  
Vol 7 (4) ◽  
pp. e35406 ◽  
Author(s):  
Ellen Fátima Caetano Lança ◽  
Belisa Maria Lopes Magalhães ◽  
Sheila Vitor-Silva ◽  
André Machado Siqueira ◽  
Silvana Gomes Benzecry ◽  
...  
Keyword(s):  
Risk Factors ◽  
Intensive Care ◽  
Plasmodium Vivax ◽  
Intensive Care Units ◽  
Pediatric Intensive Care ◽  
Brazilian Amazon ◽  
Pediatric Intensive Care Units
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