scholarly journals Psychophysiological Status and Life Quality in Individuals with Metabolic Syndrome Living in Central Kazakhstan

2020 ◽  
Vol 8 (B) ◽  
pp. 463-469
Author(s):  
Berik Koichubekov ◽  
Marina Sorokina ◽  
Ilya Korshukov ◽  
Riszhan Bakirova ◽  
Ernur Bekov ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Nervous System ◽  
Trait Anxiety ◽  
Bodily Pain ◽  
Life Quality ◽  
Pain Syndrome ◽  
The Metabolic Syndrome ◽  
Circulatory System Diseases ◽  
High Level ◽  
Psychophysiological Status

BACKGROUND: Morbidity rate of circulatory system diseases (CSD) in Kazakhstan continues to grow and the metabolic syndrome (MetS) contributes significantly to cardiovascular risk development. It was known that MetS altered autonomic nervous system (ANS) by decreasing parasympathetic activity and global heart rate variability (HRV), at the same time, the decrease in sympathetic modulation is unclear. Studies investigated associations between anxiety and MetS disorders are rather controversial. Research findings of the MetS influence on health-related quality of life (HRQoL) were also contradictory. The above-mentioned justifies the necessity of research to clarify and deepen the MetS etiology and pathogenesis, as well as to improve its diagnostics efficiency and treatment. AIM: The research goals were to study psychophysiological status and HRQoL in individuals with MetS living in Central Kazakhstan. MATERIALS AND METHODS: Three hundred MetS patients were examined in Karaganda city clinical hospital. Statistical methods and spectral analysis of HRV, simple visual-motor reaction (SVMR), the Spielberger State-Trait Anxiety Inventory, and the Lüscher color test were used. SF-36 questionnaire was used for HRQoL assessment. RESULTS: General decrease in the activity of both sympathetic and parasympathetic branches of ANS was observed in MetS patients. More than half of the examined MetS patients have had a high level of trait anxiety. Most MetS patients have had a low level of the central nervous system (CNS) functional activity. MetS patients are active both in physical and social spheres. Bodily pain syndrome greatly influences MetS patients’ life quality. The patients evaluate their health level as being low. CONCLUSION: Individuals with MetS living in Central Kazakhstan had decreased activity of ANS, prevalence of inhibition processes in CNS, high level of trait anxiety, and bodily pain syndrome affecting life quality.

scholarly journals New ideas about the pathogenesis of osteoarthritis, the role of metabolic disorders

2019 ◽  
Vol 16 (2) ◽  
pp. 75-82 ◽  
Author(s):  
Lyudmila I. Alekseeva
Keyword(s):  
Metabolic Syndrome ◽  
Musculoskeletal Diseases ◽  
Clinical Manifestations ◽  
Pain Syndrome ◽  
Functional Condition ◽  
Current Data ◽  
Rapid Progression ◽  
Open Label ◽  
The Metabolic Syndrome ◽  
Definition Of

The article highlights the current data on the prevalence and pathogenesis of osteoarthritis (OA), presents a new definition of the disease, research results on the heterogeneity of OA, its relationship with obesity and metabolic syndrome. Obesity is one of the main factors in the development and more rapid progression of OA, and the presence of metabolic syndrome not only increases the risk of developing the disease, but also determines its severity. It is noted that with an increase of the components of the metabolic syndrome, the severity of OA increases. Therefore, hyperuricemia is associated with the presence of osteophytes and the progression of osteoarthritis, hyperglycemia - with the severity of the clinical manifestations and radiological progression. Much attention is given to the treatment of patients with OA and The European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) recommendations for the treatment of knee joints OA updated in 2019. In which for the first time a symptomatic slow-acting drugs for osteoarthritis (SYSADOAs) are assigned as the basis in the treatment of OA. The data on the effectiveness of some drugs from this group are presented. The glycosaminoglycan-peptide complex, which contains pharmacologically high-quality chondroitin sulfate when administered intramuscularly, has a significant effect on the symptoms, and in case of continued use, slows the progression of OA. The multicenter open-label prospective study of diacerein in patients with knee-joint OA combined with metabolic syndrome showed that during therapy pain syndrome and stiffness are reduced, and functional condition of the joints and quality of life of patients improves quickly and significantly. In addition, the positive effect of the drug on some components of the metabolic syndrome was demonstrated: a significant decrease in body mass index, low density lipoproteins, triglycerides, glucose and uric acid.

scholarly journals Peculiarities of emotional sphere in the military with diseases of the nervous system complicated by sexual dysfunctions

2019 ◽  
pp. 90-97
Author(s):  
A. B. Shangin ◽  
A. Yu. Emelianov ◽  
G. O. Andreeva
Keyword(s):  
Nervous System ◽  
Trait Anxiety ◽  
Neurological Diseases ◽  
Well Being ◽  
Sexual Disorders ◽  
Sexual Dysfunctions ◽  
Professional Performance ◽  
Eysenck Personality Inventory ◽  
High Level ◽  
The Military

Relevance. Diseases of the nervous system considerably complicate professional performance of military men. Employees of the EMERCOM and other military are constantly engaged in stressful activities; hence, pathology of the nervous system is often associated with sexual dysfunctions. Intention – To study sexual and emotional dysfunction and personality accentuations in themilitary with diseases of the nervous system.Methods. The research was focused on a group of 146 men 25–55 years old with pathology of the nervous system. Standard clinical and neurological examination was carried out with assessment for sexual dysfunctions using questionnaires “Male sexual function” and “Male copulative function”. Emotional sphere was assessed via psychological tests: Well-being– activity–mood, Eysenck Personality Inventory, State-Trait Anxiety Inventory, Leonhard–Schmieschek questionnaire.Results and Discussion. Associated sexual dysfunctions (decreased neurohumoral, mental, erectile and ejaculatory components of copulation cycle) were found in 60.3 % of patients irrespective of specific neurologic pathology, age or sexual constitution. Statistically significant (p < 0.05) decrease in overall well-being and mood, as well as high state and trait anxiety and neuroticism were revealed in those with sexual dysfunctions. A direct link between sexual dysfunctions and emotive, pedantic, dysthymic person accentuations are noted. At patients with sexual dysfunctions gradual decrease in health status, activity, mood and increase of situational and personal anxiety, and also a high level neuroticism in comparison from patients without sexual frustration is revealed. Personality accentuations, such as stuck, pedant, exalted, emotive, demonstrative, were most common in patients with sexual dysfunctions, that is consistent with data of other authors. However, they result from a combined influence of adverse factors, rather than personality disorders.Conclusion. Sexual dysfunctions significantly aggravate a course of neurological diseases, are associated with affective disorders and increased personality accentuations. For effective treatment of neurological diseases, it’s important to reveal and timely correct psychological and sexual dysfunction in the military. “Male copulative function” questionnaire is optimal for rapid diagnosis of male sexual disorders. 

scholarly journals BIOCHEMICAL DISORDER OBSERVED IN A DYSAUTONOMIC: ABOUT A CASE

2020 ◽  
Vol 8 (12) ◽  
pp. 280-282
Author(s):  
Z. Tahiri ◽  
◽  
A. Boukhira ◽  
G. Kassal ◽  
S. Chellak ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Nervous System ◽  
Autonomic Nervous System ◽  
The Body ◽  
Military Hospital ◽  
Sympathetic Hyperactivity ◽  
Autonomic Nervous ◽  
The Metabolic Syndrome ◽  
Cardiology Department ◽  
Valuable Role

The autonomic nervous system (SNA) innervates all the organs and ensures the homeostasis of the body, the disorder of the latter causes a pathology called dysautonomy in this work we will try to report the biochemical disorders observed in a dysautonomic patient. This is a 32-year-old patient who went back to the cardiology department of the 3rd military hospital of Laayoune for high Blood pressure and headaches a complete etiological assessment is done and who found hyperlipidemia and hyperglycemia echocardiography is normal, holter tensionel showed high diastolic arterial pressure exploration of the autonomic nervous system gave sympathetic hyperactivity. Biochemical disorders have defined the metabolic syndrome, which is strongly related to morbidity and cardiovascular mortality. The laboratory plays a valuable role in determining the criteria defining metabolic syndrome.

Role of the Autonomic Nervous System in the Endothelial Dysfunction of the Metabolic Syndrome

2011 ◽  
Vol 7 (2) ◽  
pp. 73-79
Author(s):  
Patricio Lopez-Jaramillo ◽  
Dora Ines Molina ◽  
Alba Aguillon ◽  
Diego Gomez-Arbelaez ◽  
Aristides Sotomayor-Rubio ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Nervous System ◽  
Autonomic Nervous System ◽  
Endothelial Dysfunction ◽  
Autonomic Nervous ◽  
The Metabolic Syndrome

scholarly journals Does Physical Activity Lower the Risk for Metabolic Syndrome: A Longitudinal Study of Physically Active Elderly Women

2020 ◽  
Author(s):  
Izabela Zając-Gawlak ◽  
Jana Pelclová ◽  
Dorota Groffik ◽  
Miroslava Pridalová ◽  
Agnieszka Nawrat-Szołtysik ◽  
...  
Keyword(s):  
Physical Activity ◽  
Metabolic Syndrome ◽  
Older Women ◽  
Elderly Women ◽  
Physically Active ◽  
The Metabolic Syndrome ◽  
The Mean ◽  
High Level ◽  
High Density Cholesterol ◽  
Mean Concentration

Abstract Background: There are few studies assessing the health of older women with respect to their physical activity. This study sought to determine whether changes in the physical activity of 59 women aged 60+ measured seven years apart and the risk of the participants developing the metabolic syndrome (MetS) were related to each other. Methods: The physical activity of the participants was measured using the accelerometers in 2009 and 2016. Their risk for the MetS was assessed as per the NCEP-ATP III criteria. Results: The number of steps the participants took daily increased between 2009 and 2016 from 10.944±3,560 to 11.652±4865. Women who maintained a high level of physical activity between the measurements, or increased it, had a significantly higher mean concentration of high-density cholesterol in 2016 (80.3 vs. 64.5 mg/dL and 79.2 vs. 66.9mg/dL, respectively). In the latter, a lower concentration of triglycerides (TG) (123.8 vs. 158.3mg/dL) was also observed. In 2016, only 7 women met 3 or more criteria for MetS compared with 24 in 2009; at the same time, the mean number of the MetS criteria met by a participant fell from 2.2±1.4 to 1.4±1.0.Conclusions: The number of MetS criteria that the participants met in 2016 was lower than in 2007, probably due to the high number of steps taken daily. Therefore, their risk of developing cardiovascular diseases was lower too.

scholarly journals ANXIETY AND DEPRESSIVE DISORDERS IN PATIENTS WITH ARTERIAL HYPERTENSION

2021 ◽  
Vol 74 (3) ◽  
pp. 455-459
Author(s):  
Oleksandr Yu. Polishchuk ◽  
Viktor K. Tashchuk ◽  
Natalia I. Barchuk ◽  
Tetiana M. Amelina ◽  
Svitlana I. Hrechko ◽  
...  
Keyword(s):  
Arterial Hypertension ◽  
Trait Anxiety ◽  
State Anxiety ◽  
Depressive Disorders ◽  
Life Quality ◽  
Severe Depression ◽  
Significant Difference ◽  
Trait And State Anxiety ◽  
Gender Based ◽  
High Level

The aim: To study the influence of anxiety and depressive disorders on life quality of patients with arterial hypertension. Materials and methods: 55 patients with arterial hypertension (AH) of 2nd stage were examined to reach the goal. Age diapason was 25-73 years, the middle age was 53.56+10.28. There were 58.2% (32) of women and 41.8% (23) of men among the patients. Results: Results analysis of the investigation of patients with arterial hypertension and anxiety and depressive disorders using the Spielberger-Khanin anxiety inventory showed moderate (30.9%) and high (69.1%) level of trait anxiety. As for the state anxiety the high level of it was confirmed in 74.6% of studied patients and moderate level of state anxiety in 25.5% of patients. During the analysis of gender-based distribution the trait anxiety level was significantly higher in women (p<0.05). Results of PHQ-9 showed subclinical depression level (12.7%), mild (49.1%) and moderate (16.4%). Moderate manifestations of depression were found in 12.7%, severe depression in 9.1% (5 individuals). As for the gender-based distribution, anxiety indicators were significantly higher in women (p<0.01). HADS method did not show significant difference of depression levels of gender-based distribution. Conclusions: The majority of individuals with arterial hypertension and nonpsychotic mental disorders have a high level of trait and state anxiety. Direct correlation was found between the trait anxiety indicator and depression severity, which were defined according to HADS and PHQ-9 questionnaires. The level of anxiety and depressive episode severity were found to be reliably higher in women in gender-based distribution, that/which was accompanied by decrease in most of the life quality indicators.

scholarly journals Obesity-Related Metabolic Syndrome: Mechanisms of Sympathetic Overactivity

2013 ◽  
Vol 2013 ◽  
pp. 1-12 ◽  
Author(s):  
Maria Paola Canale ◽  
Simone Manca di Villahermosa ◽  
Giuliana Martino ◽  
Valentina Rovella ◽  
Annalisa Noce ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Metabolic Syndrome ◽  
Nervous System ◽  
Sympathetic Nervous System ◽  
Sympathetic Overactivity ◽  
Area Of Interest ◽  
The Metabolic Syndrome ◽  
Sympathetic Nervous ◽  
Permissive Role

The prevalence of the metabolic syndrome has increased worldwide over the past few years. Sympathetic nervous system overactivity is a key mechanism leading to hypertension in patients with the metabolic syndrome. Sympathetic activation can be triggered by reflex mechanisms as arterial baroreceptor impairment, by metabolic factors as insulin resistance, and by dysregulated adipokine production and secretion from visceral fat with a mainly permissive role of leptin and antagonist role of adiponectin. Chronic sympathetic nervous system overactivity contributes to a further decline of insulin sensitivity and creates a vicious circle that may contribute to the development of hypertension and of the metabolic syndrome and favor cardiovascular and kidney disease. Selective renal denervation is an emerging area of interest in the clinical management of obesity-related hypertension. This review focuses on current understanding of some mechanisms through which sympathetic overactivity may be interlaced to the metabolic syndrome, with particular regard to the role of insulin resistance and of some adipokines.

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