Joint association of moderate-to-vigorous intensity physical activity and sedentary behavior with incident functional limitation: data from the Osteoarthritis Initiative (OAI)

2021 ◽  
pp. jrheum.201250
Author(s):  
Hiral Master ◽  
Louise M. Thoma ◽  
Dorothy D. Dunlop ◽  
Meredith B. Christiansen ◽  
Dana Voinier ◽  
...  

Objective To examine joint association of moderate-to-vigorous intensity physical activity (MVPA) and sedentary behavior with the risk of developing functional limitation 4 years later in adults with knee OA. Methods Using 48-month (baseline) accelerometry data from Osteoarthritis Initiative, , we classified participants as Active-Low Sedentary (≥1 10-minute bout/week of MVPA, lowest tertile for standardized sedentary time), Active-High Sedentary (≥1 10-minute bout/week of MVPA, top two tertiles for standardized sedentary time), Inactive-Low Sedentary (0 10-minute bout/week of MVPA, lowest tertile for standardized sedentary time) and Inactive-High Sedentary (0 10-minute bout/week of MVPA, top two tertiles for standardized sedentary time) groups. Functional limitation was defined as >12sec for five repetition sit-to-stand test (5XSST) and <1.22m/sec gait speed during 20-meter walk test. To investigate the association of exposure groups with risk of developing functional limitation 4 years later, we calculated risk ratios(aRR) adjusted for potential confounders. Results Of 1,091 and 1,133 participants without baseline functional limitation, based on 5XSST and 20-meter walk test, respectively, 15% and 21% developed functional limitation 4 years later. Active- High Sedentary group didn’t have, while Inactive-Low Sedentary, and Inactive-High Sedentary groups had increased risk of developing functional limitations compared to Active-Low Sedentary group. Inactive-Low Sedentary group had 72% (aRR[95% confidence interval]1.72[1.00, 2.94]) and 52% (1.52[1.03, 2.25]) more risk of developing functional limitation based on 5XSST and 20-meter walk test, respectively, compared to Active-Low Sedentary group. Conclusion Regardless of sedentary category, being inactive (0 10-minute bouts/week in MVPA) may increase risk of developing functional limitation in adults with knee OA.

Author(s):  
Sebastien F.M. Chastin ◽  
Duncan E. McGregor ◽  
Stuart J.H. Biddle ◽  
Greet Cardon ◽  
Jean-Philippe Chaput ◽  
...  

Background: Crucial evidence gaps regarding: (1) the joint association of physical activity and sedentary time with health outcomes and (2) the benefits of light-intensity physical activity were identified during the development of recommendations for the World Health Organization Guidelines on physical activity and sedentary behavior (SB). The authors present alternative ways to evidence the relationship between health outcomes and time spent in physical activity and SB and examine how this could be translated into a combined recommendation in future guidelines. Methods: We used compositional data analysis to quantify the dose–response associations between the balance of time spent in physical activity and SB with all-cause mortality. The authors applied this approach using 2005–2006 National Health and Nutrition Examination Survey accelerometer data. Results: Different combinations of time spent in moderate- to vigorous-intensity physical activity, light-intensity physical activity, and SB are associated with similar all-cause mortality risk level. A balance of more than 2.5 minutes of moderate- to vigorous-intensity physical activity per hour of daily sedentary time is associated with the same magnitude of risk reduction for all-cause mortality as obtained by being physically active according to the current recommendations. Conclusion: This method could be applied to provide evidence for more flexible recommendations in the future with options to act on different behaviors depending on individuals’ circumstances and capacity.


Author(s):  
Kaiyun Tan ◽  
Li Cai ◽  
Lijuan Lai ◽  
Zhaohuan Gui ◽  
Xia Zeng ◽  
...  

Background: Time spent in different intensity-specific physical activities is codependent, but the substitution effect of different activities on weight status changes in children remains unclear. This study aims to investigate the prospective association between reallocating time in different intensities of physical activity and weight status changes among Chinese children. Methods: A national sample of 15,100 normal-weight children aged 7–18 years (46.7% boys) were recruited in September 2013 and followed up for nine months. Vigorous-intensity physical activity (VPA), moderate-intensity physical activity (MPA), walking, and sedentary time were obtained by International Physical Activity Questionnaire Short Form (IPAQ-SF). Height and weight were objectively measured, by which body mass index (BMI) and BMI z-score were calculated. Weight status was classified by the Chinese criteria for 7- to 18-year-old children. Isotemporal substitution analyses (including single-factor model, partition model, and isotemporal substitution model) were applied to examine the association of time allocation with weight status changes. Results: Each 30 min/day of increase in VPA was favorably associated with a 13.2% reduced risk of incident overweight/obesity in a single-factor model and a 15.6% reduced risk in a partition model. Negative associations were found between VPA, MPA, walking and the risk of being underweight in the single-factor model, but not in the partition model. In substitution models, replacing 30 min/day sedentary time with an equal amount of VPA was favorably associated with a 16.1% reduction of the risk of being overweight/obese. Conclusion: These findings highlight the need for promoting vigorous-intensity physical activity in children.


2005 ◽  
Vol 17 (1) ◽  
pp. 31-40 ◽  
Author(s):  
Abigail Fisher ◽  
John J. Reilly ◽  
Colette Montgomery ◽  
Louise A. Kelly ◽  
Avril Williamson ◽  
...  

This study examined whether there was a significant seasonal variation in objectively measured habitual physical activity and sedentary behavior in young children. Participants were children who attend nursery in Glasgow, Scotland, and measurements were taken using uniaxial accelerometry over 3 to 6 days. There were small but significant seasonal associations with physical activity and sedentary behavior (ANOVA: p < .001 in both cases). Total physical activity (accelerometry cpm) was significantly lower in spring than in summer, fall, and winter. We also found slight but significant seasonal variations in time spent in low-intensity activity and in moderate-to-vigorous-intensity activity. Sedentary time was significantly lower in summer vs. spring and in fall vs. spring. The present study suggests that seasonality plays only a limited role in physical activity and sedentary behavior in young children in our setting. Single measures of these variables should be adequate for research purposes in the absence of marked seasonal variability. In our sample and setting, the limited degree of seasonality precluded identification of major seasonal barriers to and opportunities for physical activity.


Author(s):  
Harukaze Yatsugi ◽  
Tao Chen ◽  
Si Chen ◽  
Kenji Narazaki ◽  
Sho Nagayoshi ◽  
...  

Background: The amounts of moderate-to-vigorous-intensity physical activity (MVPA), light-intensity physical activity (LPA), and sedentary time (ST) by sex, age, and body mass index (BMI) in older Japanese adults have not been known. We conducted this study to determine the actual physical activity (PA) and ST in this population. Subjects and Methods: A total of 3998 community-dwelling Japanese adults aged ≥65 years were investigated. Their levels of PA and ST and number of steps taken daily were assessed for seven consecutive days by a tri-axial accelerometer. Normative values of daily PA and ST were analyzed by age and BMI groups in the men and the women and are presented as mean, median, or decile. Results: The subjects generally adhered to the PA guideline, i.e., ≥10 metabolic equivalents (METs)·hour MVPA per week. Older age was associated with lower adherence to the PA guideline. Conclusions: Normative values (mean, median, or decile) were yielded for MVPA, LPA, and ST based on accelerometer readings in a large sample of older community-dwelling Japanese adults. One-half of the subjects’ waking time was spent being sedentary, and >70% of the subjects met the current PA guideline by engaging in MVPA.


Author(s):  
Simone J. J. M. Verswijveren ◽  
Karen E. Lamb ◽  
Anna Timperio ◽  
Jo Salmon ◽  
Rohan M. Telford ◽  
...  

Sedentary and physical activity patterns (bouts/breaks) may be important for cardiometabolic health in early life. This study aimed to examine cross-sectional associations of total daily volume and patterns across the activity spectrum with cardiometabolic risk factors in youth aged 7–13 years. Objectively measured accelerometer and cardiometabolic risk factor data were pooled from two studies (n = 1219; 69% valid accelerometry). Total daily volume of sedentary time and light-, moderate-, and vigorous-intensity physical activity was determined. Time in sustained bouts and median bout lengths of all intensities and breaks in sedentary time were also calculated. Outcomes included body mass index, waist circumference, blood pressure, blood lipids, and a cardiometabolic summary score. Regression models revealed beneficial associations between total daily volumes of moderate- and vigorous-intensity physical activity and cardiometabolic risk. Time spent in ≥1 min vigorous-intensity physical activity bouts was beneficially associated with cardiometabolic risk, yet this disappeared after adjusting for total vigorous-intensity physical activity and confounders. Time accumulated in light- (≥1 min; ≥5 min) and moderate-intensity (≥1 min) physical activity bouts was detrimentally associated with cardiometabolic risk. Total daily volume and activity patterns may have implications for cardiometabolic risk early in life. Sporadic physical activity may be more beneficial for health than sustained physical activity.


2020 ◽  
Author(s):  
Simone Johanna Josefa Maria Verswijveren ◽  
Karen E. Lamb ◽  
Josep A. Martín-Fernández ◽  
Elisabeth Winkler ◽  
Rebecca M. Leech ◽  
...  

Abstract Background The consequences for youth cardiometabolic risk might depend on whether sedentary time and physical activity are accumulated sporadically (in shorter bouts) or in a sustained pattern (in longer bouts). This study aimed to: 1) describe daily time-use compositions of youth, including time spent in shorter and longer bouts of sedentary behaviour and physical activity; and 2) examine associations between time-use compositions with cardiometabolic biomarkers.Methods Accelerometer and cardiometabolic biomarker data (adiposity, blood pressure, lipids) from 7–13 year olds (mean ± SD: 10.4 ± 1.7) from two Australian studies were pooled (complete cases adiposity n = 772). A time-use composition of nine components was formed using compositional data analysis: time in shorter and longer bouts of sedentary behaviour, light-, moderate- and vigorous-intensity physical activity, and “other time” (i.e., non-wear/sleep). Shorter and longer bouts of sedentary time were defined as < 5 and ≥ 5 min, respectively. Longer light-, moderate- and vigorous-intensity physical activity bouts were defined as ≥ 1 min. Linear regression models examined associations between overall time-use composition and cardiometabolic biomarkers. Then, associations between ratios of longer relative to shorter activity patterns, and each intensity relative to more intense activities and/or “other time”, with cardiometabolic biomarkers were derived.Results Confounder-adjusted models showed that the overall time-use composition was associated with zBMI, waist circumference, systolic blood pressure, high-density lipoprotein cholesterol, triglycerides, and a combined cardiometabolic risk score. Specifically, more time in longer relative to shorter bouts of light-intensity physical activity was associated with greater zBMI (β = 1.79, SE = 0.70, p = 0.010) and waist circumference (β = 17.28, SE = 4.87, p < 0.001). More time in longer relative to shorter bouts of vigorous-intensity physical activity was also associated with higher waist circumference (β = 2.54, SE = 1.14, p = 0.026). More relative time in total light- and vigorous-intensity physical activity (including longer and shorter bouts) was associated with lower waist circumference. In contrast, more relative time in sedentary behaviour and moderate-intensity physical activity was detrimental for waist circumference.Conclusions Accumulating physical activity in frequent short bursts may be beneficial for adiposity compared to engaging in the same amount of these intensities in longer bouts.Trial registration: 'Lifestyle Of Our Kids’ (ACTRN12615000066583 [23/01/2015]) and ‘Transform-Us!’ (ACTRN12609000715279 [19/08/2009], ISRCTN83725066 [30/06/2010]).


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