Sexually Transmitted Infections: Prevention, Diagnosis, and Treatment in Primary Care

2019 ◽  
Vol 48 (9) ◽  
pp. e370-e375
Author(s):  
Gregg Joseph Montalto
2003 ◽  
Vol 32 (2) ◽  
pp. 128-129
Author(s):  
Jill Huppert ◽  
Elizabeth Goodman ◽  
Jane Khour ◽  
Gail Slap

2011 ◽  
Vol 2 (3) ◽  
pp. 209-212 ◽  
Author(s):  
Susan E. Rubin ◽  
Elizabeth M. Alderman ◽  
Jason Fletcher ◽  
Giselle Campos ◽  
Lucia F. O’Sullivan ◽  
...  

2021 ◽  
Author(s):  
Carolina Guiriguet ◽  
Mireia Alberny ◽  
Ermengol Coma ◽  
Carme Roca ◽  
Francesc Fina ◽  
...  

Abstract Background: The COVID-19 pandemic and related control measures have affected the diagnosis of other diseases, including sexually transmitted infections (STI). Our aim is to analyse the impact of the COVID-19 pandemic on the incidence of STI diagnosed in primary care.Methods: Time-series study of STI, using data from primary care electronic health records in Catalonia (Spain) from January 2016 to March 2021. We obtained the monthly expected incidence of STI using a temporary regression, where the response variable was the incidence of STI from 2016 to 2019 and the adjustment variables were the trend and seasonality of the time series. Excess or reduction of STI were defined as the number of observed minus the expected cases, globally and stratified by age, sexe, type of STI and socioeconomic status.Results: Between March 2020 and March 2021 we observed a reduction of 20.2% (95% CI: 13.0% to 25.8%) on STI diagnoses compared to the expected. This reduction was greater during the lockdown period (-39%), in women (-26.5%), in people aged under 60 years (up to -22.4% in people aged 30-59 years), less deprived areas (-24%) and some types of STI, specially chlamydia (-32%), gonorrhea (-30.7%) and HIV (-21.5%). Conversely, syphilis and non-specific STI were those with lesser reductions with -3.6% and -7.2%, respectively,Conclusions: The COVID-19 pandemic has impacted on STI incidence, reducing the number of diagnoses performed in primary care and raising concerns about future evolution of STI trends. Those STI that are less symptomatic or diagnosed through screening will deserve special attention regarding potential diagnostic delays.


Venereology ◽  
2022 ◽  
Vol 1 (1) ◽  
pp. 23-46
Author(s):  
Benjamin Silverberg ◽  
Amy Moyers ◽  
Tate Hinkle ◽  
Roanna Kessler ◽  
Nancy G. Russell

The Centers for Disease Control and Prevention (CDC) recently updated their Sexually-Transmitted Infection (STI) Treatment Guidelines with a revision to the approach to gonococcal infections in December 2020 and other STIs in July 2021. This article reviews the new recommendations and highlights important updates from the 2015 iteration that are crucial for primary care and community health practice.


BMJ Open ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. e050407
Author(s):  
Ioana D Olaru ◽  
Mutsawashe Chisenga ◽  
Shunmay Yeung ◽  
David Mabey ◽  
Michael Marks ◽  
...  

ObjectiveUrinary tract infections (UTIs) are common in primary care. The yield of urine cultures in patients with UTI symptoms can be considerably different between high-income and low-income settings. This study aimed to explore possible causes of negative urine cultures in patients presenting with symptoms of UTI to primary health clinics in Harare.DesignCross-sectional study.SettingNine primary health clinics in Harare, Zimbabwe.ParticipantsAdults presenting with symptoms of UTIs between March and July 2020.Primary outcome measuresUrine samples underwent dipstick testing, microscopy, culture, and testing for sexually transmitted infections (STIs) using GeneXpert and for the presence of antibiotic residues using an antibiotic bioassay. The primary outcomes were the number and proportion of participants with evidence of STIs, prior antibiotic exposure, leucocyturia and UTIs.ResultsThe study included 425 participants with a median age of 37.3 years, of whom 275 (64.7%) were women. Leucocyturia was detected in 130 (30.6%, 95% CI 26.2% to 35.2%) participants, and 96 (22.6%, 95% CI 18.7% to 26.9%) had a positive urine culture for a uropathogen. Chlamydia trachomatis, Neisseria gonorrhoeae and Trichomonas vaginalis were detected in 43/425 (10.1%, 95% CI 7.4% to 13.4%), 37/425 (8.7%, 95% CI 6.2% to 11.8%) and 14/175 (8.0%, 95% CI 4.4% to 13.1%) participants, respectively. Overall, 89 (20.9%, 95% CI 17.2% to 25.1%) participants reported either having taken prior antibiotics or having had a positive urine bioassay. In 170 (40.0%, 95% CI 35.3% to 44.8%) participants, all of the tests that were performed were negative.ConclusionsThis study found a high prevalence of STIs and evidence of prior antimicrobial use as possible explanations for the low proportion of positive urine cultures.


JAMA ◽  
2022 ◽  
Vol 327 (2) ◽  
pp. 161
Author(s):  
Susan Tuddenham ◽  
Matthew M. Hamill ◽  
Khalil G. Ghanem

2014 ◽  
Vol 25 (12) ◽  
pp. 878-886 ◽  
Author(s):  
Danielle Albuquerque Pires Rocha ◽  
Roberto Alexandre Alves Barbosa Filho ◽  
Josiane Montanho Mariño ◽  
Cristina Maria Borborema dos Santos

2014 ◽  
Vol 104 (12) ◽  
pp. 2313-2320 ◽  
Author(s):  
Freya Spielberg ◽  
Vivian Levy ◽  
Shelly Lensing ◽  
Ishita Chattopadhyay ◽  
Lalitha Venkatasubramanian ◽  
...  

2002 ◽  
Vol 13 (9) ◽  
pp. 606-611 ◽  
Author(s):  
F M-T F Behets ◽  
J Andriamiadana ◽  
D Randrianasolo ◽  
D Rasamilalao ◽  
N Ratsimbazafy ◽  
...  

Women seeking care in Madagascar for genital discharge ( n =1066) were evaluated for syphilis seroreactivity; bacterial vaginosis (BV) and trichomoniasis. Chlamydial infection was assessed by ligase chain reaction (LCR) and by direct immunofluorescence (IF); gonorrhoea by direct microscopy, culture and LCR. Leucocytes were determined in endocervical smears and in urine using leucocyte esterase dipstick (LED). Gonococcal isolates were tested for minimal inhibitory concentrations. BV was found in 56%, trichomoniasis in 25%, and syphilis in 6% of the women. LCR detected gonorrhoea in 13% and chlamydial infection in 11% of the women. Detection of Gram(-) intracellular diplococci in endocervical smears, and gonococcal culture were respectively 23% and 57% sensitive and 98% and 100% specific compared to LCR. Chlamydia antigen detection by IF was 75% sensitive and 77% specific compared to LCR. Leucocytes in endocervical smears and LED testing lacked precision to detect gonococcal and chlamydial infections. Of 67 gonococcal strains evaluated, 19% were fully susceptible to penicillin, 33% to tetracycline; all were susceptible to ciprofloxacin, ceftriaxone, and spectinomycin. Patients who present with genital discharge in Madagascar should be treated syndromically for gonococcal and chlamydial infections and screened for syphilis. Gonorrhoea should be treated with ciprofloxacin.


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