Optimization of Ultra-High Pressure Extraction Process of Polysaccharides from Dendrobium Candidum by Response Surface Method

2012 ◽  
Vol 550-553 ◽  
pp. 1796-1800 ◽  
Author(s):  
Xue Tao ◽  
Yao Zhan ◽  
Qiu Yan Zhou ◽  
Feng Qin Feng ◽  
Yong Yu

Ultra-high pressure extraction technique was used to extract polysaccharides from Dendrobium candidum. Extraction pressure, pressure holding time and liquid-solid ratio were found to have a significant influence on the polysaccharides extraction and were optimized by the response surface method (RSM). The obtained optimum conditions were: extraction pressure 445.28MPa, pressure holding time 6.7 minutes and liquid-solid ratio 237.91ml/g. The maximum polysaccharide yield could reach 596.75mg/g under these conditions. The ultra-high pressure extraction process was a suitable method for its higher yield and shorter extraction time compared to the water-heating extraction.

Materials ◽  
2019 ◽  
Vol 12 (21) ◽  
pp. 3552 ◽  
Author(s):  
Chun-Yi Zhang ◽  
Jing-Shan Wei ◽  
Ze Wang ◽  
Zhe-Shan Yuan ◽  
Cheng-Wei Fei ◽  
...  

To reveal the effect of high-temperature creep on the blade-tip radial running clearance of aeroengine high-pressure turbines, a distributed collaborative generalized regression extremum neural network is proposed by absorbing the heuristic thoughts of distributed collaborative response surface method and the generalized extremum neural network, in order to improve the reliability analysis of blade-tip clearance with creep behavior in terms of modeling precision and simulation efficiency. In this method, the generalized extremum neural network was used to handle the transients by simplifying the response process as one extremum and to address the strong nonlinearity by means of its nonlinear mapping ability. The distributed collaborative response surface method was applied to handle multi-object multi-discipline analysis, by decomposing one “big” model with hyperparameters and high nonlinearity into a series of “small” sub-models with few parameters and low nonlinearity. Based on the developed method, the blade-tip clearance reliability analysis of an aeroengine high-pressure turbine was performed subject to the creep behaviors of structural materials, by considering the randomness of influencing parameters such as gas temperature, rotational speed, material parameters, convective heat transfer coefficient, and so forth. It was found that the reliability degree of the clearance is 0.9909 when the allowable value is 2.2 mm, and the creep deformation of the clearance presents a normal distribution with a mean of 1.9829 mm and a standard deviation of 0.07539 mm. Based on a comparison of the methods, it is demonstrated that the proposed method requires a computing time of 1.201 s and has a computational accuracy of 99.929% over 104 simulations, which are improvements of 70.5% and 1.23%, respectively, relative to the distributed collaborative response surface method. Meanwhile, the high efficiency and high precision of the presented approach become more obvious with the increasing simulations. The efforts of this study provide a promising approach to improve the dynamic reliability analysis of complex structures.


Author(s):  
Cheng-Wei Fei ◽  
Wen-Zhong Tang ◽  
Guang-chen Bai ◽  
Zhi-Ying Chen

Around the engineering background of the probabilistic design of high-pressure turbine (HPT) blade-tip radial running clearance (BTRRC) which conduces to the high-performance and high-reliability of aeroengine, a distributed collaborative extremum response surface method (DCERSM) was proposed for the dynamic probabilistic analysis of turbomachinery. On the basis of investigating extremum response surface method (ERSM), the mathematical model of DCERSM was established. The DCERSM was applied to the dynamic probabilistic analysis of BTRRC. The results show that the blade-tip radial static clearance δ = 1.82 mm is advisable synthetically considering the reliability and efficiency of gas turbine. As revealed by the comparison of three methods (DCERSM, ERSM, and Monte Carlo method), the DCERSM reshapes the possibility of the probabilistic analysis for turbomachinery and improves the computational efficiency while preserving computational accuracy. The DCERSM offers a useful insight for BTRRC dynamic probabilistic analysis and optimization. The present study enrichs mechanical reliability analysis and design theory.


Author(s):  
Li Zhou ◽  
Zhanxue Wang ◽  
Jingwei Shi ◽  
Xiaobo Zhang

The blockerless cascade thrust reverser is one of the innovative thrust reverser systems, which replaces the traditionally mechanical blocker door with the aerodynamic blocker door by high-pressure secondary injection, thus significantly reduces the nacelle weight and the complexity of the actuator, and especially suitable for high-bypass-ratio turbofan engine. In order to obtain the optimum performance of a blockerless cascade thrust reverser system and provide the guidance for the design of the blockerless cascade thrust reverser system, a blockerless cascade thrust reverser system was studied in this paper based on the Response Surface Method (RSM), focusing on the effect of different geometric and aerodynamic parameters on the thrust reverser performance. Results show that the secondary injection with high pressure forms the blockage effect to the fan flow, then forces the fan flow to deflect and discharge from the cascade window, realizing the reverse thrust. The thrust reverser performance is mainly affected by fan pressure ratio (FPR), secondary flow pressure ratio (SPR), secondary injection position (Xjet), secondary injection angle (αjet) and cascade installation angle (β), and the dominated factors are FPR, SPR and Xjet. According to the obtained response equation of the thrust reverser performance, the relationship between reverse thrust efficiency and various parameters are clearly described, and performance of thrust reverser can be quickly evaluated. Significant interaction effects exist between different two factors, which must be taken into consideration in the design process of the blockerless cascade thrust reverser system, especially for the interaction effect between FPR and Xjet, interaction effect between FPR and β. Optimization design with objective of maximum reverse thrust was carried out to determine the best parameter settings, and reverse thrust ratio ηTrev of 60% is achieved under the constraint of the secondary flow ratio.


Molecules ◽  
2018 ◽  
Vol 24 (1) ◽  
pp. 122 ◽  
Author(s):  
Li Zhang ◽  
Pengzhan Liu ◽  
Linlin Li ◽  
Ying Huang ◽  
Yunfeng Pu ◽  
...  

In this study, the ultra-high pressure extraction (UHPE) conditions for obtaining the maximum flavonoid yield from Xinjiang jujube (Ziziphus jujuba Mill.) leaves (XJL) were optimized by response surface methodology (RSM). Box–Behnken design (BBD) was applied to evaluate the effects of four variables (extraction temperature, pressure, time and liquid-to-solid ratio) on flavonoid yield. The results showed that the optimal flavonoid yield (25.45 ± 0.21 mg/g) was derived at 50.0 °C, 342.39 MPa, 11.56 min, and a liquid-to-solid ratio of 43.95 mL/g. Eight compounds were tentatively identified and quantified as kaempferol and quercetin glycosides with UPLC-ESI-MS. Compared to ultrasound-assisted extraction (UAE), UHPE can obtain higher concentrations of total flavonoids and stronger DPPH and ABTS radical-scavenging activities in a much shorter time. Therefore, UHPE is an alternative to UAE for obtaining flavonoids from XJL, which may be an optional method for large-scale industrial flavonoid extraction from XJL.


2021 ◽  
pp. 3-14
Author(s):  
Laires A. Lima ◽  
Ana I. Pereira ◽  
Clara B. Vaz ◽  
Olga Ferreira ◽  
Márcio Carocho ◽  
...  

2014 ◽  
Vol 58 ◽  
pp. 160-165 ◽  
Author(s):  
Mohammad Rostami ◽  
Vahid Farzaneh ◽  
Abolfazl Boujmehrani ◽  
Morteza Mohammadi ◽  
Hamid Bakhshabadi

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