Applications of Ceramic Nanoparticles in Nanomedicine

2012 ◽  
Vol 706-709 ◽  
pp. 467-471 ◽  
Author(s):  
Gianni Ciofani ◽  
Serena Danti ◽  
Leonardo Ricotti ◽  
Delfo D’Alessandro ◽  
Stefania Moscato ◽  
...  
Keyword(s):  
Barium Titanate ◽  
Boron Nitride ◽  
Biomedical Applications ◽  
Piezoelectric Properties ◽  
Boron Nitride Nanotubes ◽  
Ceramic Nanoparticles ◽  
High Concentrations ◽  
Barium Titanate Nanoparticles ◽  
Physical And Chemical

This paper reports on two examples of biomedical applications of ceramic nanoparticles. Thanks to their physical and chemical inertia, barium titanate nanoparticles and boron nitride nanotubes have been proved to have an optimal in vitro biocompatibility, even at high concentrations. Barium titanate nanoparticles-doxorubicin composites are successfully internalized by cancer cells, and allow for a considerable enhancement of drug up-take. Conversely, boron nitride nanotubes are explored as “nanotransducers”, thanks to their excellent piezoelectric properties. These two examples encourage further investigations and applications in biology and medicine of ceramic nanomaterials, that exhibit interesting advantages respect to traditional materials.

scholarly journals Raman active modes of single-wall boron nitride nanotubes inside carbon nanotubes

2018 ◽  
Vol 3 (2) ◽  
Author(s):  
A.M. Nassir ◽  
Ah Rahmani ◽  
M. Boutahir ◽  
B. Fakrach ◽  
H. Chadli ◽  
...  
Keyword(s):  
Boron Nitride ◽  
Inelastic Neutron Scattering ◽  
Large Diameter ◽  
Chemical Properties ◽  
Spatial Dimension ◽  
Inelastic Neutron ◽  
Boron Nitride Nanotubes ◽  
Hybrid Nanostructures ◽  
Wave Number ◽  
Physical And Chemical

The structure of boron–nitride nanotubes (BNNTs) is very similar to that of CNTs, and they exhibit many similar physical and chemical properties. In particular, a single walled boron nitride nanotube (BNNT) and a single walled carbon nanotube (CNT) have been reported. The spectral moment’s method (SMM) was shown to be a powerful tool for determining vibrational spectra (infrared absorption, Raman scattering and inelastic neutron-scattering spectra) of harmonic systems. This method can be applied to very large systems, whatever the type of atomic forces, the spatial dimension, and structure of the material. The calculations of vibrational properties of BNNT@CNT double-walled hybrid nanostructures are performed in the framework of the force constants model, using the spectral moment's method (SMM). A Lennard–Jones potential is used to describe the van der Waals in-teractions between inner and outer tubes in hybrid systems. The calculation of the BNNT@CNT Raman active modes as a function of the diameter and chirality of the inner and outer tubes allows us to derive the diameter dependence of the wave number of the breathing-like modes, intermediate-like modes and tangential-like modes in a large diameter range. These predictions are useful to interpret the experimental data.

Multimodal luminescent-magnetic boron nitride nanotubes@NaGdF4:Eu structures for cancer therapy

2014 ◽  
Vol 50 (33) ◽  
pp. 4371-4374 ◽  
Author(s):  
Xia Li ◽  
Nobutaka Hanagata ◽  
Xuebin Wang ◽  
Maho Yamaguchi ◽  
Wei Yi ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Boron Nitride ◽  
Boron Nitride Nanotubes ◽  
Shell Structures ◽  
Core Shell

Boron nitride nanotubes@NaGdF4:Eu composites with core@shell structures were fabricated to trace and manipulate BNNTsin vitro.

scholarly journals Pectin-coated boron nitride nanotubes: In vitro cyto-/immune-compatibility on RAW 264.7 macrophages

2016 ◽  
Vol 1860 (4) ◽  
pp. 775-784 ◽  
Author(s):  
Antonella Rocca ◽  
Attilio Marino ◽  
Serena Del Turco ◽  
Valentina Cappello ◽  
Paola Parlanti ◽  
...  
Keyword(s):  
Boron Nitride ◽  
Boron Nitride Nanotubes ◽  
Raw 264.7 ◽  
Raw 264.7 Macrophages

Preparation of Boron Nitride Nanotubes Aqueous Dispersions for Biological Applications

2008 ◽  
Vol 8 (12) ◽  
pp. 6223-6231 ◽  
Author(s):  
Gianni Ciofani ◽  
Vittoria Raffa ◽  
Arianna Menciassi ◽  
Paolo Dario
Keyword(s):  
Boron Nitride ◽  
Neuroblastoma Cell ◽  
Neuroblastoma Cell Line ◽  
Boron Nitride Nanotubes ◽  
Human Neuroblastoma Cell ◽  
Biological Applications ◽  
Human Neuroblastoma ◽  
Living Material ◽  
First Time

While in the last years applications of carbon nanotubes in the field of biotechnology have been largely proposed, biomedical applications of boron nitride nanotubes (BNNTs) are yet totally unexplored. BNNTs have very interesting physical properties that should be exploited in the biomedical field. At this date, studies on their biocompatibility are completely missing and the first issue behind this investigation is the dispersion of BNNTs in aqueous solutions. In this paper the authors propose, for the first time, a technique for obtaining BNNT stable dispersions suitable for biological applications, based on polyethyleneimine (PEI) water solutions. Based on authors' knowledge, in vitro testing performed on human neuroblastoma cell line (SH-SY5Y) is the first study of interaction between BNNTs and living material. Experimental results showed a satisfactory cell viability up to a concentration of 5.0 μg/ml PEI-BNNTs in the cell culture medium.

scholarly journals Synthesis of boron nitride nanotubes and their applications

2015 ◽  
Vol 6 ◽  
pp. 84-102 ◽  
Author(s):  
Saban Kalay ◽  
Zehra Yilmaz ◽  
Ozlem Sen ◽  
Melis Emanet ◽  
Emine Kazanc ◽  
...  
Keyword(s):  
Boron Nitride ◽  
Biomedical Applications ◽  
Storage Capacity ◽  
Boron Nitride Nanotubes ◽  
Synthesis Methods ◽  
Neutron Capture Therapy ◽  
Insulation Resistance ◽  
Hydrogen Storage Capacity ◽  
Resistance To Oxidation ◽  
Wide Range

Boron nitride nanotubes (BNNTs) have been increasingly investigated for use in a wide range of applications due to their unique physicochemical properties including high hydrophobicity, heat and electrical insulation, resistance to oxidation, and hydrogen storage capacity. They are also valued for their possible medical and biomedical applications including drug delivery, use in biomaterials, and neutron capture therapy. In this review, BNNT synthesis methods and the surface modification strategies are first discussed, and then their toxicity and application studies are summarized. Finally, a perspective for the future use of these novel materials is discussed.

A Review of Synthesis and Applications of Boron Nitride Nanotubes (BNNTs) with Future Prospects

2021 ◽  
Vol 05 ◽  
Author(s):  
Mohd Yusuf ◽  
Shafat Ahmad Khan
Keyword(s):  
Carbon Nanotubes ◽  
Boron Nitride ◽  
Mechanical Strength ◽  
Biomedical Applications ◽  
Boron Nitride Nanotubes ◽  
Advanced Materials ◽  
Future Prospects ◽  
Specific Chemical ◽  
Chemical Structures ◽  
Potential Applications

: Emerging nanotechnology in the early 1990s introduced nanoscaled and advanced materials such as Carbon Nanotubes (CNT) with specific chemical structures and exceptionally unique properties. Among various nanostructures, particularly nanotubes have shown their specific values due to their inherent characteristics. With time, new vistas were opened for developing other nanotube-based materials due to their remarked mechanical strength and versatile applications. In recent decades, BNNTs with promising applicability have been synthesized via several methods. This review highlights the synthetic strategies of Boron Nitride Nanotubes (BNNTs) with their potential applications in various applied sectors, including energy, electronics, and biomedical applications.

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