scholarly journals Characterization of Best Practices for Customer/Supplier Collaboration in Co-innovation Projects

2020 ◽  
Vol 15 (4) ◽  
pp. 5-18
Author(s):  
Carlos Abraham Moya ◽  
Vincent Boly ◽  
Laure Morel ◽  
Daniel Gálvez ◽  
Mauricio Camargo
Keyword(s):  
Best Practices ◽  
Innovation Projects ◽  
Supplier Collaboration

scholarly journals Best practices for bioinformatic characterization of neoantigens for clinical utility

2019 ◽  
Vol 11 (1) ◽  
Author(s):  
Megan M. Richters ◽  
Huiming Xia ◽  
Katie M. Campbell ◽  
William E. Gillanders ◽  
Obi L. Griffith ◽  
...  
Keyword(s):  
Best Practices ◽  
Clinical Utility

scholarly journals Optimal protocols for sequence-based characterization of the human vaginal microbiome

2020 ◽  
Author(s):  
Luisa W. Hugerth ◽  
Marcela Pereira ◽  
Yinghua Zha ◽  
Maike Seifert ◽  
Vilde Kaldhusdal ◽  
...  
Keyword(s):  
16S Rrna ◽  
Best Practices ◽  
Gene Sequencing ◽  
16S Rrna Gene Sequencing ◽  
Rrna Gene ◽  
Vaginal Microbiome ◽  
Wide Range ◽  
Rrna Gene Sequencing ◽  
Good Agreement

AbstractThe vaginal microbiome has been connected to a wide range of health outcomes. This has led to a thriving research environment, but also to the use of conflicting methodologies to study its microbial composition. Here we systematically assess best practices for the sequencing-based characterization of the human vaginal microbiome. As far as 16S rRNA gene sequencing is concerned, the V1-V3 region has the best theoretical properties, but limitations of current sequencing technologies mean that the V3-V4 region performs equally well. Both of these approaches present very good agreement with qPCR quantification of key taxa, provided an appropriate bioinformatic pipeline is used. Shotgun metagenomic sequencing presents an interesting alternative to 16S amplification and sequencing, but it is not without its challenges. We have assessed different tools for the removal of host reads and the taxonomic annotation of metagenomic reads, including a new, easy-to-build and – use, reference database of vaginal taxa. This strategy performed as well as the best performing previously published strategies. Despite the many advantages of shotgun sequencing none of the shotgun approaches assessed here had as good agreement with the qPCR data as 16S rRNA gene sequencing.ImportanceThe vaginal microbiome has been connected to a wide range of health outcomes, from susceptibility to sexually transmitted infections to gynecological cancers and pregnancy outcomes. This has led to a thriving research environment, but also to conflicting available methodologies, including many studies that do not report their molecular biological and bioinformatic methods in sufficient detail for them to be considered reproducible. This can lead to conflicting messages and delay progress from descriptive to intervention studies. By systematically assessing best practices for the characterization of the human vaginal microbiome, this study will enable past studies to be assessed more critically and assist future studies in the selection of appropriate methods for their specific research questions.

scholarly journals Roles, Responsibilities, and Needs of Institutional GME Leaders: A Multinational Characterization of Designated Institutional Officials

2019 ◽  
Vol 11 (4s) ◽  
pp. 110-117 ◽  
Author(s):  
Sawsan Abdel-Razig ◽  
Halah Ibrahim
Keyword(s):  
Professional Development ◽  
Medical Education ◽  
Middle East ◽  
Best Practices ◽  
Job Descriptions ◽  
The Past ◽  
Professional Development Needs ◽  
Accredited Institutions

ABSTRACT Background Since 2012, several academic centers in the Middle East have attained accreditation by the Accreditation Council for Graduate Medical Education International (ACGME-I). An emerging group of GME leaders have assumed the role of designated institutional official (DIO), leading their institutions to accreditation. Despite these DIOs' key positions in driving GME reform, there is a lack of published studies on the roles, responsibilities, and needs of DIOs in international settings. Objective We examined the characteristics, roles, responsibilities, and needs of DIOs in the Middle East. Methods A questionnaire was electronically distributed from December 2018 to February 2019 to all current and former DIOs in ACGME-I accredited institutions in the Middle East. Results Of 16 surveys sent, 11 (69%) were returned. All DIOs were physicians; the majority were women less than 55 years of age, and assumed the role of DIO in the past decade. Most DIOs felt prepared for the position and well supported by their institution and their program directors. All reported having additional roles beyond the DIO position. Most identified the most challenging aspect of their role related to GME budgets, training for their responsibilities, sharing best practices and documents such as DIO job descriptions and other key documents, and DIO training. Conclusions ACGME-I accreditation is a critical driver of efforts to define the DIO role. DIOs in the Middle East share common perceptions, experiences, and needs. Further research should identify professional development needs in an increasingly diverse international worldwide DIO community.

scholarly journals Best supply chain management practices and high-performance firms

2018 ◽  
Vol 67 (9) ◽  
pp. 1482-1509 ◽  
Author(s):  
Moh’d Anwer AL-Shboul ◽  
Jose Arturo Garza-Reyes ◽  
Vikas Kumar
Keyword(s):  
Supply Chain ◽  
Supply Chain Management ◽  
Best Practices ◽  
High Performance ◽  
Best Practice ◽  
Management Practices ◽  
Developing Economies ◽  
Chain Management ◽  
Content Type ◽  
Supplier Collaboration

PurposeThe purpose of this paper is to investigate the best supply chain management (SCM) practices that are implemented in medium- and large-sized Gulf manufacturing firms (MFs).Design/methodology/approachThis study has explored seven SCM practices, i.e. supplier collaboration, flexibility with partners, usage of internet, customer focus (CF), lean production (LP), internal integration (II) and quality management (QM). It assumes that the best-performing firms must be the ones implementing the best practices.t-test and multiple linear regression analyses were used to establish the best practices, implemented by medium and large-sized Gulf MFs.FindingsThe results showed that QM, CF and supplier collaboration are considered as best SCM practices in Gulf MFs. Usage of internet may have been the best practice previously, but not anymore. LP cannot yet be qualified as, but may develop into the best SCM practice.Practical implicationsThe study provides a useful contribution to the field of best SCM practices as it provides better decision-making insights and a benchmarking base to top managers, policy makers and academics. It is likely to result in increased overall performance of their firms.Originality/valueThe study provides an understanding of the distinctive characteristics of the best SCM practices, implemented by Gulf MFs. It has broader implications for all MFs, particularly in developing economies where the growth of manufacturing and effective management of their supply chains is a key element for the economic development.

scholarly journals Best Practices for Purification and Characterization of PAMAM Dendrimer

2012 ◽  
Vol 45 (12) ◽  
pp. 5316-5320 ◽  
Author(s):  
Douglas G. Mullen ◽  
Ankur Desai ◽  
Mallory A. van Dongen ◽  
Mark Barash ◽  
James R. Baker ◽  
...  
Keyword(s):  
Best Practices ◽  
Pamam Dendrimer ◽  
Purification And Characterization

scholarly journals Geriatric Delirium Care: Using Chart Audits to Target Improvement Strategies

2017 ◽  
Vol 20 (4) ◽  
pp. 246-252 ◽  
Author(s):  
Carla A. Loftus ◽  
Lesley A. Wiesenfeld
Keyword(s):  
Best Practices ◽  
Best Practice ◽  
Median Length ◽  
Local Data ◽  
General Internal ◽  
Delirium Management ◽  
Chart Audits ◽  
Inpatient Units ◽  
Surgical Unit

BackgroundOur hospital identified delirium care as a quality improvement target. Baseline characterization of our delirium care and deficits was needed to guide improvement efforts.MethodsTwo inpatient units were selected: 1) A general internal medicine unit with a focus on geriatrics, and 2) a surgical unit. Retrospective chart audits were conducted for all patients over age 50 admitted during a one-month period to compare delirium care with best practice guideline (BPG) recommendations, and to determine the incidence of missed cases of delirium and negative outcomes in patients with delirium. The aim was to gather local data to prioritize improvement efforts and mobilize stakeholders.Results186 charts were reviewed: 17 patients had physiciandiagnosed delirium, 21 patients had missed delirium, and 148 patients had no delirium. Compliance with delirium BPGs was variable, but generally poor. There was a trend towards missed delirium and physician-diagnosed delirium being associated with greater odds of having above-median length of stay and lower odds of discharge home compared to no delirium diagnosis.ConclusionOverall, the chart audits confirmed delirium underrecognition and poor adherence to best practices in delirium management. Granular analysis of this data was used to mobilize stakeholders and prioritize improvement plans.

scholarly journals A Practical Guide to Analyzing and Reporting the Movement of Nanoscale Swimmers

2021 ◽  
Author(s):  
Wei Wang ◽  
Thomas Mallouk
Keyword(s):  
Brownian Motion ◽  
Data Analysis ◽  
Best Practices ◽  
General Public ◽  
Experimental Designs ◽  
Practical Guide ◽  
Widespread Interest

The recent invention of nanoswimmers– synthetic, powered objects with characteristic lengths in the range of 10-500 nm - has sparked widespread interest among scientists and the general public. As more researchers from different backgrounds enter the field, the study of nanoswimmers offers new opportunities but also significant experimental and theoretical challenges. In particular, the accurate characterization of nanoswimmers is often hindered by strong Brownian motion, convective effects, and the lack of a clear way to visualize them. When coupled with improper experimental designs and imprecise practices in data analysis, these issues can translate to results and conclusions that are inconsistent and poorly reproducible. This Perspective follows the course of a typical nanoswimmer investigation from synthesis through to applications and offers suggestions for best practices in reporting experimental details, recording videos, plotting trajectories, calculating and analyzing mobility, eliminating drift, and performing control experiments, in order to improve the reliability of the reported results.

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