scholarly journals Investigation of the effect of body mass index (BMI) on semen parameters and male reproductive system hormones

2017 ◽  
Vol 89 (3) ◽  
pp. 219 ◽  
Author(s):  
Mehmet Zeynel Keskin ◽  
Salih Budak ◽  
Evrim Emre Aksoy ◽  
Cem Yücel ◽  
Serkan Karamazak ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Sperm Count ◽  
Reproductive Hormones ◽  
Semen Parameters ◽  
Total Testosterone ◽  
Significant Difference ◽  
Group 3 ◽  
Group 2 ◽  
Group 1

Aim: To evaluate the effects of body mass index (BMI) ratio on semen parameters and serum reproductive hormones. Materials and methods: The data of 454 patients who prsented to male infertility clinics in our hospital between 2014 and 2015 were analyzed retrospectively. Weight, height, serum hormone levels and semen analysis results of the patients were obtained. BMI values were calculated by using the weight and height values of the patients and they were classified as group 1 for BMI values ≤ 25 kg/m2, as group 2 for BMI values 25-30 kg/m2 and as group 3 for BMI values ≥ 30 kg/m2. Results: The mean values of BMI, semen volume, concentration, total motility, progressive motility, total progressive motile sperm count (TPMSC), normal morphology according to Kruger, head abnormality, neck abnormality, tail abnormality, FSH, LH, prolactin, T/E2, total testosterone and estradiol parameters of the patients were considered. Patients were divided according to BMI values in Group 1 (n = 165), Group 2 (n = 222) and Group 3 (n = 56). There was no statistically significant difference in terms of all variables between the groups. Conclusions: We analyzed the relationship between BMI level and semen parameters and reproductive hormones, demonstrating no relationship between BMI and semen parameters. In our study, BMI does not affect semen parameters although it shows negative correlation with prolactin and testosterone levels.

scholarly journals Impact of percutaneous embolization versus subinguinal microsurgical ligation on semen parameters in primary varicocele patients: comparative study

2020 ◽  
Vol 51 (1) ◽  
Author(s):  
Haytham M. Nasser ◽  
Ahmed Hussein ◽  
Gad M. Behairy ◽  
Mostafa Abdo
Keyword(s):  
Sperm Count ◽  
Semen Analysis ◽  
Statistical Significance ◽  
Semen Parameters ◽  
Male Factor ◽  
Percutaneous Embolization ◽  
Significant Difference ◽  
Group 2 ◽  
Group 1

Abstract Background Varicocele is an abnormally dilated pampiniform plexus of the veins within the spermatic cord and is considered the most common correctable cause of male factor infertility. Many approaches are described for treatment either surgical (tradition inguinal, subinguinal, and laparoscopic) or non-surgical percutaneous embolization. During the period from August 2017 to December 2018, we prospectively analyzed the preoperative and post-operative alteration of semen parameters (at 3 and 9 months) of the data collected from 63 patients with clinically evident varicocele referred to our tertiary hospital. Patients were divided into two groups: group 1, thirty-three patients who underwent subinguinal microsurgical ligation, and group 2, thirty patients who underwent percutaneous embolization. Results Sixty-three patients enrolled in this study were divided in two groups: group 1, patients who underwent surgery, and group 2, patients who underwent embolization; the mean age is 24.6 ± 1.27 years in group 1 and 23.7 ± 2 years in group 2; there was no statistically significant difference between the two groups as regards BMI, diabetes, hypertension, and smoking. Bilaterality was present in 15.2% of group 1 patients and 10% in group 2 patients (P value 0.06). Most of the patients were classified as grades 2 and 3 with no statistical significance regarding severity of the disease. Preoperative semen parameters for patients including sperm count, motility, and abnormal forms showed no statistically significant difference between the two groups. Post-intervention semen analysis was done twice during follow-up after 3 months and 9 months from the date of intervention. After 3 months, the semen parameters were improved in both groups in spite of the higher sperm count in group 2 but with no statistical significance. After 9 months follow-up, semen analysis showed persistent increase in sperm mobility in group 1 patients in comparison to group 2 patients. Both groups had better improvement in count of normal form with no statistical significant change. Conclusion Improvement of semen parameters while treating primary varicocele by either subinguinal microsurgery approach or percutaneous embolization shows equivalent outcomes.

The importance of laboratory tests and Body Mass Index in the diagnosis of acute appendicitis

2020 ◽  
Vol 92 (5) ◽  
pp. 1-5
Author(s):  
Atakan Ozkan ◽  
Aylin Hande Gokce ◽  
Feridun Suat Gokce
Keyword(s):  
Body Mass Index ◽  
Acute Appendicitis ◽  
Body Mass ◽  
The Body ◽  
Distribution Width ◽  
Lymphocyte Ratio ◽  
Group 4 ◽  
Group 3 ◽  
Group 2 ◽  
Group 1

<b>Background:</b> Acute appendicitis is the most common cause of acute abdomen. Delay in diagnosis increases the mortality and morbidity. <br><b>Aim: </b>In this study, we aimed to investigate whether the body mass index is useful in diagnosis and whether the neutrophil /lymphocyte and platelet/lymphocyte ratios can help in determining the inflammation level of acute appendicitis. <br><b>Meterial and Methods:</b> Cases of appendectomy performed between June 2012 and December 2018 in our clinic were analyzed retrospectively. Based on the pathology results of the cases included in the study, 4 groups were formed, i.e.: Group 1 (initial stage), Group 2 (catarrhal stage), Group 3 (phlegmonous-gangrenous stage) and Group 4 (perforation). The study compared age, body mass index, leukocyte values, red cell distribution width (RDW), neutrophil/lymphocyte ratio (NLR), platelet /lymphocyte ratio (PLR), and mean platelet volume (MPV) between groups. <br><b> Results:</b> 828 cases were included in the study. When compared between groups, the values of Group 3 and Group 4 were higher than those of Group 1 and Group 2 for PLR and NLR. There was no difference in RDW and MPV values in the blood. When Body Mass Index (BMI) was compared between groups, it was found to be significantly higher with increasing histopathological stage. <br><b>Conclusion:</b> In acute appendicitis, the blood leukocyte value, elevated PLR and NLR are helpful in diagnosis. We aimed to emphasize that the diagnosis of acute appendicitis is delayed in patients with a BMI above 30 and/or at age of over 40 years, with the perforation rate being determined more frequently.

scholarly journals Diabetes during Pregnancy: Influence of Body Mass Index on Composite Morbidity

2017 ◽  
Vol 07 (02) ◽  
pp. e128-e133
Author(s):  
Amy O'Neil Dudley ◽  
Zachary Jenner ◽  
Hector Mendez-Figueroa ◽  
Viviana Ellis ◽  
Suneet Chauhan
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Fourth Degree ◽  
Arterial Ph ◽  
Maternal And Neonatal Outcomes ◽  
Group 3 ◽  
Group 2 ◽  
Umbilical Arterial Ph ◽  
Diabetes And Obesity ◽  
Group 1

Objective This study aims to compare composite maternal and neonatal morbidities (MM, NM) among pregnant women with diabetes mellitus whose body mass index (BMI) at delivery was < 30 (group 1), 30.0 to 39.9 (group 2), and ≥ 40 kg/m2 (group 3). We hypothesized that increased BMI class at delivery would be associated with worsening maternal and neonatal outcomes. Methods This is a retrospective cohort study. MM was defined as: chorioamnionitis, wound infection, eclampsia, diabetic ketoacidosis, hypoglycemia admission, third/fourth degree laceration, and/or death. NM was defined as umbilical arterial pH < 7.0, 5 minute Apgar < 4, respiratory distress syndrome, mechanical ventilation, neonatal sepsis, stillbirth, and/or death. Odds ratios were adjusted for possible confounders. Results MM was noted in 8, 13, and 24% of groups 1, 2, and 3, respectively, and significantly more common in group 2 versus 1 (adjusted odds ratio [aOR]: 1.66) and group 3 versus 1 (aOR: 3.06). NM was noted in 7, 8, and 15% of each BMI group, respectively, and differed significantly between group 3 vs. 2 (aOR: 1.77). Conclusions The increased rate of morbidities between the BMI groups is useful to inform diabetic women and highlights the need for further investigation of diabetes and obesity as comorbidities in pregnancy.

Association of choroidal structure and body mass index in an adult population

2021 ◽  
pp. 112067212110437
Author(s):  
Emine Temel ◽  
Nazife Aşikgarip ◽  
Kemal Örnek
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Structural Parameters ◽  
Adult Population ◽  
Enhanced Depth Imaging ◽  
Group 4 ◽  
Choroidal Structure ◽  
Group 3 ◽  
Group 2 ◽  
Group 1

Purpose: To determine the relation of choroidal structural parameters and body mass index (BMI) in an adult population. Methods: About 144 eyes of 144 healthy individuals were incorporated. There were four groups according to BMI values: Group 1 (⩽18.5), group 2 (18.6–24.9), group 3 (25.0–29.9), and group 4 (30.0–34.9). The enhanced depth imaging optical coherence tomography images were binarized using Image-J software. Choroidal thickness (CT), circumscribed choroidal area (CCA), luminal area (LA), stromal area (SA), and choroidal vascularity index (CVI) were calculated. Results: Mean subfoveal, nasal, and temporal CT were lower in group 4 rather than group 1 ( p = 0.032, p = 0.001, and p < 0.001, respectively). Mean nasal and temporal CT also showed a decrease in group 4 as compared to group 2 ( p = 0.04 and p = 0.039). Mean CCA and LA were decreased in group 4 in comparison to group 3 ( p = 0.001 and p = 0.001), group 2 ( p < 0.001 and p < 0.001), and group 1 ( p = 0.001 and p < 0.001). Mean SA showed a decrease only in group 3 rather than group 2 ( p = 0.021) and group 1 ( p = 0.008). Mean CVI was decreased in group 3 and group 4 in comparison to group 1 ( p < 0.001 and p < 0.001) and group 2 ( p = 0.002 and p < 0.001). Conclusion: Increased BMI percentile was associated with a decrease in CT and structural parameters.

Abstract P116: Higher Body Mass Index Trajectories Are Associated With Lower Levels Of Physical Activity Measured By A Smartwatch

Circulation ◽  
2021 ◽  
Vol 143 (Suppl_1) ◽  
Author(s):  
Michael M Hammond ◽  
Joanne M Murabito ◽  
Ludovic Trinquart ◽  
Emelia J Benjamin ◽  
Honghuang Lin ◽  
...  
Keyword(s):  
Physical Activity ◽  
Body Mass Index ◽  
Body Mass ◽  
Habitual Physical Activity ◽  
Bmi Trajectories ◽  
Group 3 ◽  
Group 2 ◽  
The Relationship ◽  
Bmi Trajectory ◽  
Group 1

Introduction: The prevalence of obesity is rising. Most previous studies that examined the relationship between body mass index (BMI) and physical activity measured BMI at a single time-point, ignoring the time-varying nature of BMI. The relationship between BMI trajectories and habitual physical activity in community settings remains unclear. Objective: To assess the relationship between BMI trajectories and habitual physical activity measured by daily steps from a smartwatch, among participants enrolled in the electronic Framingham Heart Study (eFHS). We hypothesized that participants whose BMI trajectories increased over a 14-year period prior to the step assessment take fewer daily steps, compared to participants who maintained stable BMI trajectories during the same time period. Methods: We used a semiparametric group-based modelling method to identify BMI trajectory patterns. Participants who attended exams 1, 2, and 3 were included in building the trajectories. Daily steps were recorded from the smartwatch provided at exam 3 with “active days” defined as days with ≥ 5watch wear-hours. We excluded participants with <30 active days. The median follow-up period for step count was 357 days (IQR: 467 days). We used generalized linear models that accounted for correlation between daily steps in the same individuals to examine the longitudinal relationship between BMI trajectory groups and daily step counts, adjusting for relevant covariates. Results: We identified three trajectory groups for the 837 eFHS participants. Group 1 included 292 participants (mean age 54 years, 57% women) whose BMI was stable (slope: 0.005, p=0.75); Group 2 included 468 participants (mean age 53 years, 56% women) whose BMI increased slightly (slope: 0.123, p<9.2e-17); and Group 3 included 77 participants (mean age 50 years, 70% women) who had the largest increase of BMI (slope: 0.318, p=2.8e-22).Adjusting for age, sex, wear time and race/ethnicity, participants in group 3 (Δ1437 steps P< 0.0001) and Group 2 (Δ422 steps, P=0.04) took significantly fewer steps, compared to participants in Group 1 (Model 1). The effect sizes were slightly attenuated but remained significant after additionally adjusting for hypertension, type 2 diabetes, current smoking, and cardiovascular disease: Group 3 took 1258 fewer steps, P=0.0001; Group 2 took 406 fewer steps, P=0.04 (Model 2). We further adjusted for sleep apnea, education, and marital status in Model 3 and observed that on average Group 3 took 1120 fewer steps (P= 0.0007) and Group 2 took 382 fewer steps (P= 0.06), compared to Group 1. Conclusion: Participants whose BMI trajectory increased over time took significantly fewer steps compared to participants with more stable BMI trajectories. Our findings suggest that levels of physical activity may correlate with greater weight gain during adulthood.

scholarly journals Influence of Body Mass Index on Mechanical Properties in People With Obesity

2021 ◽  
Author(s):  
Serkan Usgu ◽  
Engin Ramazanoğlu ◽  
Yavuz Yakut
Keyword(s):  
Mechanical Properties ◽  
Body Mass Index ◽  
Body Mass ◽  
The Other ◽  
Positive Correlation ◽  
Weak Positive Correlation ◽  
Group 3 ◽  
Group 2 ◽  
The Right ◽  
Group 1

Abstract Background: The study was to determine influence of body mass index on muscular mechanical properties in people with obesity.Methods: A total of 300 individuals (mean age: 27.31±7.21 years) were participated. The participants were assigned in groups base on BMI classification (Group 1 (BMI=18.50-24.99 kg/m2), Group 2 (BMI=25.00-29.99 kg/m2), and Group 3 (BMI≥30 kg/m2)). The biceps brachii (BB), biceps femoris (BF) were measured bilaterally using the "MyotonPRO" device. Results: All mechanical properties of the right and left BB muscle, left BF tone and stiffness were found significantly difference between groups (p<0.05). The bilateral BB tone in Group 3 was lower than the other two groups. The right BB stiffness of Group 2 was found to be higher compared to the other two groups (p<0.05). While the right and left BB elasticity was similar in Groups 2 and 3, it was lower compared to Group 1 (p<0.05). The left BF tone and stiffness of Group 3 were found to be significantly higher than Groups 1 and 2 (p<0.05).The right BB tone showed a weak negative correlation with BMI in females, and for left side in males. A weak positive correlation was found between the right and left BB elasticity and BMI in males and females. The left-right BF tone and left BF stiffness showed a weak positive correlation in males. Conclusions: The bilateral BB tone and elasticity decreased, and the left BF stiffness increased as BMI increased. Different mechanical properties were observed in sex comparasion base on BMI clasification. The BB and BF mechanical properties were affected more in males than females.

scholarly journals A comparative study of physiological and hematological profile of preeclampsia in relation to body mass index

2020 ◽  
Vol 11 (2) ◽  
pp. 2584-2590
Author(s):  
Sabir Ali Shaikh ◽  
Rajagopalan Vijayaraghavan ◽  
Das Subir Kumar ◽  
Chowdhury Ranita Roy
Keyword(s):  
Blood Pressure ◽  
Body Mass Index ◽  
Body Mass ◽  
Control Groups ◽  
Respective Control ◽  
Hematological Profile ◽  
Significant Difference ◽  
Maternal Morbidity And Mortality ◽  
Group 3 ◽  
Group 2

Preeclampsia (PE) is a major reason for maternal morbidity and mortality globally. Studies showed that body mass index (BMI) is one of the risk factors of PE. In this study, the BMI and physiological and hematological profile were associated with predicting the severity of preeclampsia, so that proper counseling and antenatal care could be given for good pregnancy outcome. The study was carried out on 100 healthy normotensive pregnant and 100 diagnosed preeclamptic women. Healthy pregnant and PE were categorized into three groups based on BMI, on WHO criteria. BMI group 1 (<25 Kg/m2) considered as normal, group 2 (25 – 30 Kg/m2) as over-weight and group 3 (>30 Kg/m2) obese. Systolic blood pressure (SBP), diastolic blood pressure (DBP), hemoglobin (Hb), white blood corpuscles (WBC), red blood corpuscles (RBC) and platelets were compared in control and PE groups. Then the respective control groups were compared with PE groups. The prevalence of overweight was more in PE groups when compared to normotensive pregnancy (P=0.004). Statistically, a significant difference was not observed in BMI group1, group 2 and group 3 of control and PE in relation to SBP, DBP, Hb, WBC, RBC and platelets. But a statistically significant difference was made when respective control groups were compared with PE (P<0.005). BMI does not have any statistically significant association with SBP, DBP, Hb, WBC, RBC and platelets. BMI could not be considered as a predictor or severity of preeclampsia. 

Relations between body mass index trajectories and habitual physical activity measured by smartwatch: Insights from the electronic cohort of the Framingham Heart Study (Preprint)

2021 ◽  
Author(s):  
Michael M Hammond ◽  
Yuankai Zhang ◽  
Chathurangi H. Pathiravasan ◽  
Honghuang Lin ◽  
Mayank Sardana ◽  
...  
Keyword(s):  
Physical Activity ◽  
Body Mass Index ◽  
Body Mass ◽  
Framingham Heart Study ◽  
Female Group ◽  
Heart Study ◽  
Bmi Trajectories ◽  
Group 3 ◽  
Group 2 ◽  
Group 1

BACKGROUND The prevalence of obesity is rising. Most previous studies that examined the relations between body mass index (BMI) and physical activity (PA) measured BMI at a single time-point. The association between BMI trajectories and habitual PA remains unclear. OBJECTIVE We assessed the relations between BMI trajectories and habitual PA, among participants enrolled in the electronic Framingham Heart Study (eFHS). METHODS We used a semiparametric group-based modelling to identify BMI trajectories from eFHS participants who attended research examinations 1, 2, and 3 over a 14-year period. Daily steps were recorded from the smartwatch provided at examination 3. We excluded participants with <30 days or <5 hours of smartwatch wear data. We used generalized linear models to examine the association between BMI trajectories and daily step counts. RESULTS We identified three trajectory groups for the 837 eFHS participants (mean age: 53 years; 58% Female). Group 1 included 292 participants whose BMI was stable (slope: 0.005, P=.75); Group 2 included 468 participants whose BMI increased slightly (slope: 0.123, P<.001); and Group 3 included 77 participants whose BMI increased greatly (slope: 0.318, P<.001). The median follow-up period for step count was 357 days. Adjusting for age, sex, wear time, and cohort, participants in Group 2 and Group 3 took 422 steps (95% CI: -823, -21) and 1437 (95% CI: -2084, -790) fewer average daily steps, compared to participants in Group 1. After adjusting for metabolic and social risk factors, Group 2 took 382 (95% CI: -773, 10) and Group 3 took 1120 (95% CI: -1766, -475) fewer steps, compared to Group 1. CONCLUSIONS In this community-based eFHS, participants whose BMI trajectory increased greatly over time took significantly fewer steps, compared to participants with stable BMI trajectories. Our findings suggest that greater weight gain may correlate with lower levels of physical activity.

scholarly journals Biochemical and histologic changes in albino rats in response to charcoal powder exposure

2021 ◽  
Vol 15 (4) ◽  
pp. 24-36
Author(s):  
O. E. Oriakpono ◽  
◽  
C. Anuforo ◽  
E. E. Nduonofit ◽  
B. K. Deeyah ◽  
...  
Keyword(s):  
Liver Enzymes ◽  
Mean Value ◽  
Semen Parameters ◽  
Albino Rats ◽  
Skin Contact ◽  
Significant Difference ◽  
Lung Histology ◽  
Group 3 ◽  
Group 2 ◽  
Group 1

Background. In developing and under-developed countries, charcoal production predisposes workers to charcoal dust. This is a common occurrence as workers in this field are not properly protected and as such are exposed to charcoal dust through inhalation and skin contact. Charcoal comprises many components such as polycyclic aromatic hydrocarbons (PAHs). Due to the possible health risk associated with such exposure, this study was designed to determine the effects of charcoal powder of particle size 125 µm - 150 µm on certain biomarkers in male albino rats. Albino rats were used because of their similar physiology to humans. Materials and Methods. 20 albino rats weighing between 250 g and 300 g were used for this study; they were randomly distributed in 4 groups (5 rats each) and the charcoal powder was incorporated into their feed at different percentages; control, group 1 (10 % charcoal), group 2 (30 % charcoal) and group 3 (charcoal powder bedding) for 50 days. Using standard procedures and methods, the following parameters were tested: Hematological parameters, semen parameters, liver enzymes, renal function, hormones and lung histology. Results. The results indicated a decrease in the level of liver enzymes AST (IU/L) and ALT (IU/L) in group 1, group 2 and group 3 when compared to the control with the lowest value of 48.75 IU/L and 11.50 IU/L respectively recorded in group 2. Prolactin (mIU/L) had mean values of 1.73, 1.30 and 1.83 in group 1, group 2 and group 3 respectively while the control was 2.10. Testosterone (nmol/L) had a mean value of 1.18, 0.53 and 0.25 in group 1, group 2 and group 3, respectively, while the control was 0.90 with a significant difference (P<0.05). Creatinine (µmol/L) increased in group 1 and group 2 with a slight reduction in group 3 when compared to control (1.04) with a value of 1.35, 1.40 and 1.23, respectively. Total sperm count (´105/mL) had a mean value of 58.33, 50.00 and 43.25 in group 1, group 2 and group 3, respectively, while the control was 100.50. The lung histology for the treated groups revealed infiltration of inflammatory cells and thickening of inter-alveolar walls. Conclusion. Long term exposure to charcoal powder through nasal or oral route had serious effects on rats’ health, such as kidney damages, inflammation of the lungs and decrease in fertility in males primarily due to the presence of PAHs in charcoal.

In-vivo evaluation of the effect of cyanoacrylate on prosthetic vascular graft infection – does cyanoacrylate increase the severity of infection?

VASA ◽  
2020 ◽  
Vol 49 (4) ◽  
pp. 281-284
Author(s):  
Atıf Yolgosteren ◽  
Gencehan Kumtepe ◽  
Melda Payaslioglu ◽  
Cuneyt Ozakin
Keyword(s):  
Vascular Graft ◽  
Graft Infection ◽  
Vascular Graft Infection ◽  
Group 4 ◽  
Significant Difference ◽  
Group 3 ◽  
Group 2 ◽  
Prosthetic Vascular Graft Infection ◽  
Group 1

Summary. Background: Prosthetic vascular graft infection (PVGI) is a complication with high mortality. Cyanoacrylate (CA) is an adhesive which has been used in a number of surgical procedures. In this in-vivo study, we aimed to evaluate the relationship between PVGI and CA. Materials and methods: Thirty-two rats were equally divided into four groups. Pouch was formed on back of rats until deep fascia. In group 1, vascular graft with polyethyleneterephthalate (PET) was placed into pouch. In group 2, MRSA strain with a density of 1 ml 0.5 MacFarland was injected into pouch. In group 3, 1 cm 2 vascular graft with PET piece was placed into pouch and MRSA strain with a density of 1 ml 0.5 MacFarland was injected. In group 4, 1 cm 2 vascular graft with PET piece impregnated with N-butyl cyanoacrylate-based adhesive was placed and MRSA strain with a density of 1 ml 0.5 MacFarland was injected. All rats were scarified in 96th hour, culture samples were taken where intervention was performed and were evaluated microbiologically. Bacteria reproducing in each group were numerically evaluated based on colony-forming unit (CFU/ml) and compared by taking their average. Results: MRSA reproduction of 0 CFU/ml in group 1, of 1410 CFU/ml in group 2, of 180 200 CFU/ml in group 3 and of 625 300 CFU/ml in group 4 was present. A statistically significant difference was present between group 1 and group 4 (p < 0.01), between group 2 and group 4 (p < 0.01), between group 3 and group 4 (p < 0.05). In terms of reproduction, no statistically significant difference was found in group 1, group 2, group 3 in themselves. Conclusions: We observed that the rate of infection increased in the cyanoacyrylate group where cyanoacrylate was used. We think that surgeon should be more careful in using CA in vascular surgery.

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