scholarly journals Towards reliable in vitro models – New bi-compartmental platforms for replicating tissue barriers

2021 ◽  
Vol 4 (s1) ◽  
Author(s):  
Lorenzo P. Coppadoro ◽  
Elia Pederzani ◽  
Chiara Foglieni ◽  
Maria Lombardi ◽  
Gianfranco B. Fiore ◽  
...  

In vitro cell cultures represent a widespread methodology for pathophysiology studies with a high benefit/cost ratio. We have developed and are validating TToP, a novel, versatile, and scalable culture system allowing compartmentalized cell/tissue cultures with the aim of mimicking the human pathophysiological microenvironment of tissue barriers.

2017 ◽  
Vol 5 (4) ◽  
pp. 454-465 ◽  
Author(s):  
Ritesh Kumar Yadav ◽  
Amarjit Singh ◽  
Sandeep Jain ◽  
Ajmer Singh Dhatt

Six systemic fungicides viz.,  Kitazin 48 EC (iprobenfos), Tilt 25 EC (propiconazole), Folicur 25 EC (tebuconazole), Score 25 EC (difenoconazole), Amistar Top 325 SC (azoxystrobin 18.2% + difenoconazole 11.4%) and Nativo 75 WG  (trifloxystrobin 25% + tebuconazole 50%), and two non-systemic fungicides viz., Indofil M-45 75 WP (mancozeb) and Kocide 77 WP (copper hydroxide), were evaluated under in vitro and field conditions for their efficacy to manage purple blotch complex of onion caused by Alternaria porri and Stemphylium vesicarium. Field efficacy of  the fungicides at different concentrations were determined in controlling the purple blotch complex of onion under artificial epiphytotic conditions on bulb and seed crop (cultivar PRO-6) during the Rabi season 2014-2015 and 2015-2016, respectively. The triazole fungicides, tebuconazole and difenoconazole proved superior in inhibiting growth of A. porri and S. vesicarium under in vitro conditions, respectively. Further, foliar sprays (3 for bulb crop and 4 for seed crop) of tebuconazole 25 EC (Folicur) @ 0.1 per cent at fortnightly interval most effectively managed purple blotch complex of onion under field conditions with highest Benefit: Cost ratio (8.75:1 and 88.7:1) in bulb and seed crop, respectively. Seed-to-seed method of onion seed production recorded significantly lower disease severity and higher seed yield than that of bulb-to-seed method under natural epiphytotic conditions. The present findings can be instrumental in devising strategy for the integrated management of A. porri, S. vesicarium singly as well as in complex, serious limiting biotic factors in onion production. Int. J. Appl. Sci. Biotechnol. Vol 5(4): 554-565


2013 ◽  
Vol 655-657 ◽  
pp. 1479-1483
Author(s):  
Jiu Hui Ding ◽  
Bai Wei Guo ◽  
Shuang Wei

one hardware-in-the-loop simulation (referred to HILS) system for terminally guided projectile guidance and control system has been built, based on the analysis to the demand of HILS for the guidance and control system of the terminally guided projectile. The running process and the comparison results of the HILS & mathematical simulation have been given. The simulation results show that the movement of the terminally guided projectile could be simulated by the HILS system, which has a high benefit-cost ratio and confidence.


Author(s):  
B. Venkatesh ◽  
Y. S. Parameswari ◽  
M. Madhavi ◽  
T. Ram Prakash

A field experiment was conducted during kharif, 2019 at Professor Jayashankar Telangana State Agricultural University, Rajendranagar, Hyderabad. The experiment done with twelve treatments and three replications. The study was taken to find out which herbicide mixture most effective in controlling of weeds leads to maximum yields with higher benefit cost ratio. The results revealed that, application of herbicide mixture florpyrauxifen-benzyl + cyhalofop-butyl 10% EC 150 g/ha PoE fb hand weeding at 40 days after transplanting (DAT) gave higher yields and net returns with high benefit cost ratio (B: C) which was statistically on par with minimum competitive plot. Unweeded plot yield was deviated about 48 % compare to florpyrauxifen-benzyl + cyhalofop-butyl 10% EC 150 g/ha PoE fb hand weeding at 40 days after transplanting.


2014 ◽  
Vol 12 (1) ◽  
pp. 89-95
Author(s):  
AK Singh

Pod fly [Melanagromyza obtusa (Malloch)] is a key biotic constraint for productivity in subsistence crop protection pattern; its damage varies up to 80%; has been estimated about US $ 256 million annually. The research trial was accomplished at Research Farm of SASRD, Nagaland University during Kharif 2011 and 2012 in order to evaluate the new molecules against pod fly. The experiment was consisted 6 treatments (Trizophos 500 g ai. ha-1, Emamectine benzoate 11 g ai. ha-1, Emamectine benzoate 11 g ai. ha-1 + Acetamiprid 30 g ai. ha-1, Flubendiamide 47 g ai. ha-1, Chlorantraniliprole 40 g ai. ha-1 and Spinosade 75 g ai. ha-1) compare with control. The lowest pod damage (9.7% and 9.3%), lowest grain damage (5.3% and 5%) and highest grain yield (1202 kg ha-1 and 1209 kg ha-1) were obtained from Chlorantraniliprole followed by Emamectine benzoate+ Acetamiprid, Spinosade, Emamectine benzoate, Flubendiamide, Trizophos and all the treatments were significantly superior over control. The highest B: C ratio reward (1:4.24) was obtained from Chlorantraniliprole. The results indicated that Chlorantraniliprole was more effectual against pod damage, grain damage, yield and B: C ratio. The safer chemical control methods reduce the pod damage, grain damage and higher yield with high benefit: cost ratio, so therefore chemical control popularizes as an effective, practical alternative and makes lucrative cultivation of pigeon pea. DOI: http://dx.doi.org/10.3329/sja.v12i1.21115 SAARC J. Agri., 12(1): 89-95 (2014)


Sensors ◽  
2019 ◽  
Vol 19 (4) ◽  
pp. 899 ◽  
Author(s):  
Andreia dos Santos ◽  
Nuno Pinela ◽  
Pedro Alves ◽  
Rodrigo Santos ◽  
Ricardo Farinha ◽  
...  

Electronic skin (e-skin) is pursued as a key component in robotics and prosthesis to confer them sensing properties that mimic human skin. For pressure monitoring, a great emphasis on piezoresistive sensors was registered due to the simplicity of sensor design and readout mechanism. For higher sensitivity, films composing these sensors may be micro-structured, usually by expensive photolithography techniques or low-cost and low-customizable molds. Sensors commonly present different sensitivities in different pressure ranges, which should be avoided in robotics and prosthesis applications. The combination of pressure sensing and temperature is also relevant for the field and has room for improvement. This work proposes an alternative approach for film micro-structuration based on the production of highly customizable and low-cost molds through laser engraving. These bimodal e-skin piezoresistive and temperature sensors could achieve a stable sensitivity of −6.4 × 10−3 kPa−1 from 1.6 kPa to 100 kPa, with a very robust and reproducible performance over 27,500 cycles of objects grasping and releasing and an exceptionally high temperature coefficient of resistance (TCR) of 8.3%/°C. These results point toward the versatility and high benefit/cost ratio of the laser engraving technique to produce sensors with a suitable performance for robotics and functional prosthesis.


Author(s):  
B. M. Ranjitha ◽  
T. B. Allolli ◽  
D. R. Jhanavi ◽  
N. Kavyashree ◽  
S. Gururaj ◽  
...  

A field experiment was conducted in Dharwad district, Karnataka during kharif season of 2015-2016, with an objective to assess the effectiveness of nutrient management practices and organic amendments on yield and economics of chilli (Capsicum annuum L.) hybrid Sitara. The results revealed that the maximum yield parameters were recorded due to adoption of INM practices (among nutrient management practices) and Panchagavya (among organic amendments). INM practices and Panchagavya recorded high Benefit: cost ratio of 2.7 and 2.6 respectively.


ENTOMON ◽  
2020 ◽  
Vol 45 (4) ◽  
pp. 295-300
Author(s):  
Reshma Chandran ◽  
B. Ramesha ◽  
K.M. Sreekumar

A field study conducted to evaluate the efficacy of new molecules against okra shoot and fruit borer, Earias vitella (Fb.) during rabi and summer season revealed that Chlorantraniliprole 8.8% + Thiamethoxam17.5% SC @ 0.7 ml/l significantly reduced the percentage of shoot and fruit damage. No shoot and fruit infestation was recorded at seven and fourteen days after treatment. It was on par with the standard check Chlorantraniliprole 18.5 SC @ 0.3 ml/l followed by Novaluron 10 EC @ 2 ml/l and Lamdacyhalothrin 4.6% + Chlorantraniliprole 9.3% ZC. Chlorantraniliprole 8.8% + Thiamethoxam17.5% SC treated plots recorded highest total yield of 469.86 and 594.31 g/plant respectively. Maximum marketable yield was also recorded from Chlorantraniliprole 8.8% + Thiamethoxam17.5% SC treated plots respectively. Chlorantraniliprole 8.8% + Thiamethoxam17.5% SC also showed high benefit-cost ratio of 2.42 and 3.12 during rabi and summer season respectively.


2021 ◽  
Vol 93 (6) ◽  
pp. 53-60
Author(s):  
Marko Bašković

The COVID-19 pandemic has forced healthcare systems around the world to adopt telemedicine at an unprecedented rate. Visits to telemedicine have increased to provide access and maintain continuity of care. Internet access has almost become a necessity, and new technologies allow for the easy flow of data from patient to doctor and vice versa. Doctors of all specialties were forced to adapt to the pandemic and emerging conditions. The provision of surgical services and the learning ability of surgeons are particularly disrupted, and the pediatric surgical community is not exempt. During the pandemic, telemedicine proved to be a viable and safe technique for providing health services. In an environment of a health system that is constantly facing a shortage of resources, effective telemedicine placement can come with a high benefit-cost ratio and quality of care, while ensuring patient satisfaction.


2021 ◽  
Vol 17 (AAEBSSD) ◽  
pp. 307-310
Author(s):  
Arpita Shrivastava ◽  
Smita Singh ◽  
Veena Pani Shrivastava ◽  
Uttam Kumar Tripathi

The present investigation was carried out at the adopted villages of Krishi Vigyan Kendra, Chhatarpur during 2017-18 to demonstrate the improved variety JG 63 with the scientific package and practices to improve the production of chickpea. The treatment comprised of scientific package of practices (Improved variety JG 63 + seed treatment with Carbendazim 3g/ kg of seed and seed inoculation with Rhizobium and PSB culture each @ 10 g/ kg of seed + soil test value based fertilizer application + line sowing + adoption of IPM technique). The demonstration plot exhibited higher yield as compared to farmers plot. An average yield of chickpea in the demonstrated plot was 18.74 q/ha as compare to farmers practices 14.16 q/ha in the three years of pooled data. The improved technology gives the higher return with the high benefit cost ratio as farmer’s practices. The observed extension gap, technology gap and technology index were 4.58 q/ha, 1.26 q/ha and 6.30%, respectively. The improved variety with scientific package of practices and technical guidance contributed to increase production of chickpea and profitability of the farmers of the district.


Sign in / Sign up

Export Citation Format

Share Document