scholarly journals The managament of rare nasal mass-nasal dermoid sinus cysts: open rhinoplasty

Rare Tumors ◽  
2009 ◽  
Vol 1 (2) ◽  
pp. 121-123
Author(s):  
Emel Cadalli Tatar ◽  
Ömer Tarik Selçuk ◽  
Güleser Saylam ◽  
Ali Özdek ◽  
Hakan Korkmaz
Keyword(s):  
Differential Diagnosis ◽  
Recurrent Infection ◽  
Malignant Neoplasms ◽  
Open Rhinoplasty ◽  
Benign Neoplasms ◽  
Inflammatory Lesions ◽  
Nasal Mass ◽  
Dermoid Sinus ◽  
Post Traumatic ◽  
Male Patients

The differential diagnosis of midline nasal masses includes inflammatory lesions, post-traumatic deformities, benign neoplasms, malignant neoplasms, congenital and vascular masses. Midline congenital lesions of the nose are rare congenital anomalies. Their incidence is estimated at 1 per 20,000 to 40,000 births consisting of gliomas, encephaloceles, and nasal dermoid sinus cysts. Nasal dermoid sinus cysts account for 1–3% of dermoid cysts overall and 11–12% of head and neck dermoids. Most lesions are diagnosed within the first three years of life but in some cases the diagnosis can be prolonged. We present an 18-year old and a two and a half-year old male patients who are concerned about drainage from the tip of the nose with recurrent infection and operated with a diagnosis of nasal dermoid sinus cyst.

scholarly journals HISTOPATHOLOGICAL EXAMINATIONS PROFILE OF BLADDER DISEASES IN DR. SOETOMO GENERAL ACADEMIC HOSPITAL FROM JANUARY 2015 TO DECEMBER 2019

2022 ◽  
Vol 29 (1) ◽  
Author(s):  
Veronika Intan Krismaningrum ◽  
Anny Setijo Rahaju ◽  
Lilik Herawati ◽  
Soetojo
Keyword(s):  
Histopathological Examination ◽  
Malignant Neoplasm ◽  
Secondary Data ◽  
Malignant Neoplasms ◽  
Benign Neoplasms ◽  
Academic Hospital ◽  
Bladder Disease ◽  
Bladder Diseases ◽  
Bladder Abnormalities ◽  
Male Patients

Objective: This study aimed to analyze the profile of bladder disease in Soetomo General Hospital based on histopathological examination. Material & Methods: This study was using secondary data. Histopathological examination data of patients with bladder disease were evaluated based on age, gender, and histopathological types. Results: There were 419 patients with bladder abnormalities. Non-neoplasm bladder diseases were found in 62 patients consisted of 56 patients (90.32%) with cystitis and 6 patients (9.67%) with glandular cystitis. Neoplastic bladder diseases were found in 357 patients and were divided into benign and malignant neoplasm. Benign neoplasms were found in 11 patients consisted of 5 patients (45.45%) with UP and 6 patients (54.54%) with IUP. Malignant neoplasms were found in 340 patients consisted of 300 patients (88.23%) with urothelial carcinoma, 26 patients (7.64%) with adenocarcinoma, 14 patients (4.12%) with SCC. Moreover, six male patients with PUNLMP were also reported. Conclusion: Histopathological examination in patients with bladder abnormalities shows that neoplastic bladder diseases (357/419, 85.20%) were more common than non-neoplastic bladder disease (62/419, 14.80%).

Efficacy evaluation of the CEUS-LI-RADS-v2017 system in differential diagnosis of liver tumors

2019 ◽  
pp. 57-67
Author(s):  
A. N. Katrich ◽  
V. A. Porkhanov ◽  
N. S. Ryabin
Keyword(s):  
Risk Factors ◽  
Differential Diagnosis ◽  
Liver Tumors ◽  
Morphological Data ◽  
Malignant Neoplasms ◽  
Diagnostic Efficiency ◽  
Efficacy Evaluation ◽  
General Group ◽  
Group 2 ◽  
Group 1

Objective: efficacy evaluation of the CEUS LI RADS v2017® system for differential diagnosis of liver tumors in patients with and without cirrhosis.Materials and methods. Retrospective analysis of diagnostic results of the 165 patients with liver tumors (177 nodules) was done. All patients underwent CEUS with results interpretation in accordance to the CEUS LIRADSv2017 ® criteria. Patients were divided into 2 groups based on clinical and morphological data. Group 1 included 62 patients with cirrhosis and/or CVH. Group 2 included 110 patients without risk factors for HCC.Results. Diagnostic efficiency of CEUS LI RADS v2017® for HCC identification was: group 1 – Se – 100%, Sp – 88%, Ac – 95.5%; group 2 – Se – 100%, Sp – 68.8%, Ac – 72.7%; general group Se – 100%, Sp – 72.2%, Ac – 81.4%. In the 2nd group, 21 out of 22 neoplasms, confirmed morphologically as FNH, we classified as LR 4. By applying benign character and specific contrasting patterns of FNG, they were transferred from LR 4 to LR 3. This allowed to increase sensitivity and specificity of differential diagnosis in group 2 (Se – 100%, Sp – 90.6%, Ac – 91.8%) and in general group (Se – 100%, Sp – 90.1%, Ac – 93.2%). Diagnostic efficiency of the criteria for non hepatocellular malignant neoplasms (LR M) was: group 1 – Se – 77.8%, Sp – 100%, Ac – 97%; group 2 – Se – 90%, Sp – 96.7%, Ac – 93.6%; general group- Se – 88.1%, Sp – 98.3%, Ac – 94.9%.Conclusion. Our study confirmed high accuracy of the CEUS LI RADS v2017® system in the differential diagnosis of focal liver tumors. Modification of the system (in particular, transfer of typical FNG forms from the LR 4 category) will make it possible to increase the accuracy of diagnostics by 20%. It will allow to use the LI RADS v2017® system for interpretation CEUS not only among patients with liver cirrhosis, but also in a general group without risk factors of GCC.

scholarly journals Malignant Peripheral Nerve Sheath Tumor in the Nasal Cavity of a Neonate: A Case Report

2021 ◽  
pp. 014556132110141
Author(s):  
Xiufang Chi ◽  
Yue Wang ◽  
Haoming Yang ◽  
Cheng Xing ◽  
Jiamin Gan ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Peripheral Nerve ◽  
Nasal Cavity ◽  
Nerve Fibers ◽  
Nerve Sheath Tumor ◽  
Rare Tumor ◽  
Nasal Mass ◽  
Peripheral Nerve Sheath Tumor ◽  
Related Literature ◽  
Nerve Sheath

Malignant peripheral nerve sheath tumor (MPNST) is a rare tumor that can develop on the lining of nerves and within the network of nerve fibers in different organs, and it is commonly found in the head and neck, limbs, and trunk. These tumors can occur in patients of any age. They most commonly occur in adults aged 20 to 50 years; however, fewer cases of this tumor in children have been reported. To date, no neonatal case of MPNST in the nasal cavity has been reported. Here, we report the case of a 4-day-old female newborn who presented with a nasal mass that re-enlarged after surgery and was diagnosed as MPNST of the nasal cavity on the basis of pathological results. This is the first report of MPNST in the nasal cavity of a neonate. Differential diagnosis and treatment of nasal masses have been proposed in the related literature.

scholarly journals Schwannoma of the abdominal wall: updated literature review

2021 ◽  
Author(s):  
Tommaso Panici Tonucci ◽  
Andrea Sironi ◽  
Eleonora Pisa ◽  
Benedetta Di Venosa ◽  
Luigi Bonavina
Keyword(s):  
Differential Diagnosis ◽  
Literature Review ◽  
Abdominal Wall ◽  
Single Case ◽  
Case Reports ◽  
Rectus Abdominis ◽  
Malignant Neoplasms ◽  
Palpable Mass ◽  
Surgical Specimen ◽  
Benign Schwannoma

Summary Background Schwannoma is a benign tumor arising from Schwann cells of the peripheral nerves. It is often asymptomatic and can develop in the retroperitoneum, mediastinum, head and neck region, and upper and lower extremities. Schwannoma of the abdominal wall is extremely rare, but differential diagnosis with malignant neoplasms is important to reduce the risk of undertreatment. Methods A narrative review of abdominal wall schwannoma was performed using PubMed, EMBASE, and Web of Science database and the search terms “schwannoma”, “neurinoma”, “neurilemmoma”, “soft tissue tumors”, “neurogenic tumor”, “rectus abdominis mass”, “abdominal wall”. In addition, the hospital charts were reviewed to report the personal experience. Results Only 9 single case-reports of benign schwannoma of the abdominal wall were found in the English medical literature over the past decade. None of the patients received preoperative biopsy and all were resected with clear margins. In addition to the literature review, we report the case of a 58-year-old man referred for a palpable mass in the left upper abdominal quadrant. Ultrasonography and magnetic resonance imaging revealed a solid and well-encapsulated mass inside the left rectus abdominis muscle. A core biopsy of the lesion provided the diagnosis of cellular schwannoma and this was confirmed by histopathologic examination of the surgical specimen. Conclusions Benign schwannoma of the abdominal wall is extremely rare. Percutaneous core needle biopsy is important for the differential diagnosis with more common and biologically more aggressive malignancies, such as desmoid tumors and sarcomas, and may be relevant for planning the most appropriate management.

Intravascular Papillary Endothelial Hyperplasia of Renal Vein: Report of 2 Cases

2005 ◽  
Vol 129 (4) ◽  
pp. 516-519
Author(s):  
Mohammed Akhtar ◽  
Muhammed Aslam ◽  
Hadeel Al-Mana ◽  
Hana Bamefleh ◽  
Sultan S. Al-Khateeb ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Renal Vein ◽  
Renal Mass ◽  
Malignant Neoplasms ◽  
Renal Neoplasm ◽  
Intravascular Papillary Endothelial Hyperplasia ◽  
Process Thought ◽  
Papillary Endothelial Hyperplasia ◽  
Hilar Region ◽  
Characteristic Features

Abstract Intravascular papillary endothelial hyperplasia is a benign intravascular process thought to arise from an organizing thrombus. The lesion may present clinically as an abnormal mass and, depending on the location, may be confused with benign or malignant neoplasms. It has been described in a variety of locations. Involvement of the renal vein by papillary endothelial hyperplasia is extremely rare, with only 4 cases reported in the literature. We describe 2 additional cases. In both cases, the radiologic examination revealed a well-circumscribed mass in the hilar region of the kidney, which was considered to be a renal neoplasm. Nephrectomy specimen in each case revealed characteristic features of intravascular papillary endothelial hyperplasia. It is suggested that intravascular papillary endothelial hyperplasia should be included in the differential diagnosis of a hilar renal mass.

scholarly journals Tracheal surgery

2016 ◽  
Vol 73 (3) ◽  
Author(s):  
A. D'Andrilli ◽  
E.A. Rendina ◽  
F. Venuta
Keyword(s):  
Surgical Resection ◽  
Surgical Techniques ◽  
Treatment Modalities ◽  
Malignant Neoplasms ◽  
New Techniques ◽  
Multidisciplinary Cooperation ◽  
Post Traumatic ◽  
Post Intubation ◽  
Near Future

Surgical resection and reconstruction of the trachea can be performed both for benign and malignant diseases. The main indications for surgery include inflammatory (generally post-intubation), congenital or post-traumatic stenoses, degenerative lesions, benign or malignant neoplasms. Success can be pursued only by accurate patient selection and timing, meticulous surgical techniques, careful follow up and, when required, multidisciplinary cooperation. Although surgical resection has now become part of our surgical practice, other treatment modalities are approaching a new clinical application era, in particular tracheal transplantation and bioengineering. These new techniques will certainly offer, in the near future, improved chances to treat difficult cases.

Έκφραση πρωτεϊνών θερμικού σοκ και νεοαγγειογένεση στα νεοπλάσματα των σιελογόνων αδένων

2013 ◽  
Author(s):  
Βασίλειος Παπανικολάου
Keyword(s):  
Salivary Gland ◽  
Angiogenesis Inhibitor ◽  
Salivary Gland Neoplasms ◽  
Malignant Neoplasms ◽  
Low Grade ◽  
Benign Neoplasms ◽  
Related Molecule ◽  
Collagen Xviii ◽  
Pleomorphic Adenomas ◽  
Endothelial Marker

IntroductionSalivary gland neoplasms comprise a wide group of tumors with diverse histology and broad biologic behavior, often presenting difficulties in their definitive diagnosis and treatment. In the last decades, the prominent role of angiogenesis in the neoplastic process has been recognized, and alterations of its promoters and inhibitors have been investigated in most human tumors. However, angiogenesis in salivary gland neoplasms has not been thoroughly studied.Material and MethodsWe evaluated the immunohistochemical expression of various angiogenesis-related molecules and the vascularity of 61 malignant (16 adenoid cystic carcinomas, 12 mucoepidermoid carcinomas, 11 polymorphous low grade adenocarcinomas, 9 adenocarcinomas NOS, 6 salivary duct carcinomas, 3 carcinomas ex-pleomorphic adenomas, 2 lymphoepithelial carcinomas, 1 myoepithelial carninoma, 1 clear cell carinoma NOS) and 18 benign salivary gland neoplasms (13 pleomorphic adenomas, 5 Warthin tumours).The evaluated molecules were: angiogenesis-promoter vascular endothelial growth factor (VEGF). angiogenesis-inhibitor Endostatin. angiogenesis related molecule collagen angiogenesis related molecule HSP47. endothelial marker FVIIIR:Ag. Vascularity was assessed by calculation of MicroVessel Density (MVD) and by FVIIIR:Ag immunostaining intensity.ResultsVEGF was expressed in 83.6% of malignant and 94.44% of benign neoplasms. Endostatin was expressed in 91.8% and 100% of malignant and benign cases respectively. Collagen XVIII was expressed in 100% of both benign and malignant neoplasms. HSP47 was expressed in 78.68% of malignant and 100% of benign neoplasms.All markers predominantly showed a diffuse pattern of immunostaining (more than 50% positive cells). VEGF immunostaining intensity varied widely among cases, ranging from weak to strong for both malignant and benign cases. Endostatin, Collagen XVIII and HSP47 presented varying immunointensity for malignant cases, whereas benign cases mainly presented strong immunostaining.Statistical analysis correlated VEGF expression in malignant neoplasms with TNM stage and extraparenchymal infiltration (p=0,0005 and 0,00063 respectively). The total score of immunoreactivity for Endostatin, Collagen XVIII and HSP47 was significantly higher in benign compared to malignant cases (p=0.01, p=0.02, and p=0,00996 respectively). Furthermore, HSP47 positivity and intensity was statistically higher in benign neoplasms, compared to malignant (p=0,0067 and p=0.0249 respectively). Additionally Endostatin immunoexpression correlated with Collagen XVIII expression in benign cases (p<0.001). No association was found regarding tumor MVD. However, immunostaining intensity of the endothelial marker FVIIIR:Ag was higher in malignant tumours (p=0,013).ConclusionsOur results show that benign compared to malignant salivary gland neoplasms express higher levels of Endostatin, Collagen XVIII and HSP47. Ιn malignant neoplasms an increase in the ratio of angiogenic to angiostatic elements is observed. It suggested that enhanced angiogenesis may contribute to salivary gland carcinogenesis.

Uterine Leiomyoma or Sarcoma?

2021 ◽  
pp. 289-304
Author(s):  
Theodoros Theodoridis ◽  
Dimitra Aivazi ◽  
Leonidas Zepiridis ◽  
Nikolaos Vlachos
Keyword(s):  
Differential Diagnosis ◽  
Smooth Muscle ◽  
Connective Tissue ◽  
Muscle Cells ◽  
Uterine Sarcoma ◽  
Current Evidence ◽  
Optimal Management ◽  
Benign Neoplasms ◽  
Uterine Sarcomas ◽  
Epithelial Neoplasms

Uterine leiomyomas are benign neoplasms derived from the smooth muscle cells of the myometrium. In contrast, uterine sarcomas are rare tumors, with a prevalence of 3-7 per 100,000 women, originating from myometrial cells or endometrial connective tissue. Uterine sarcomas and especially leiomyosarcomas are more aggressive than uterine epithelial neoplasms. The differential diagnosis between leiomyoma and uterine sarcoma preoperatively remains challenging for the clinical practitioner in order to determine optimal treatment. The chapter aims to summarize current evidence regarding differential diagnosis and optimal management of these two challenging clinical entities.

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