scholarly journals Bilateral multifocal renal oncocytoma in pregnancy

Rare Tumors ◽  
2012 ◽  
Vol 4 (4) ◽  
pp. 175-177 ◽  
Author(s):  
Schalk W. Wentzel ◽  
Lodewikus P. Vermeulen
Keyword(s):  
Literature Search ◽  
Renal Tumor ◽  
Elective Caesarean Section ◽  
Renal Oncocytoma ◽  
Renal Neoplasms ◽  
Second Trimester ◽  
Renal Masses ◽  
Renal Oncocytomas ◽  
Recommended Guidelines ◽  
In Pregnancy

Renal oncocytomas are the most common benign solid renal tumor, accounting for 3–7% of renal neoplasms. Oncocytomas are multifocal in 2–12% and bilateral in 4–14% of cases. Multifocal bilateral oncocytomas represent only 1.4% of renal cases. We present an extraordinary case of a patient with multifocal bilateral renal oncocytomas during pregnancy. An electronic literature search revealed fewer than 30 reports of on cases of bilateral multifocal renal oncocytomas, none of them occurring in pregnancy. The management of this patient differed from the recommended guidelines for renal masses suspected to be malignant because elective caesarean section and nephrectomy in the second trimester was refused.

Renal Oncocytoma With Both Lymphovascular Invasion and Prominent Intracytoplasmic Vacuole-Like Spaces: A Case Report and Review of the Literature

2021 ◽  
pp. 106689692110415
Author(s):  
Xunda Luo ◽  
Christopher Preciado ◽  
Anupma Nayak ◽  
Lauren E. Schwartz ◽  
Thomas J. Guzzo ◽  
...  
Keyword(s):  
Needle Biopsy ◽  
Vascular Invasion ◽  
Lymphovascular Invasion ◽  
Renal Tumor ◽  
Renal Oncocytoma ◽  
Review Of The Literature ◽  
Renal Oncocytomas ◽  
Microscopic Features ◽  
Intracytoplasmic Vacuole ◽  
Tumor Entities

Here we report a case of renal oncocytoma in a 68 year-old male. The diagnosis was initially made on a needle biopsy 6 years prior to the partial nephrectomy. The case is unique that in addition to the gross and microscopic features commonly seen in renal oncocytomas, both lymphovascular invasion and prominent intracytoplasmic vacuole-like spaces are also present in this tumor. Although vascular invasion is increasingly recognized as compatible with renal oncocytoma, intracytoplasmic vacuoles are a rare and unusual finding that may lead to diagnostic difficulty. The diagnosis of renal oncocytoma was confirmed after immunohistochemistry was performed to argue against succinate dehydrogenase deficient renal cell carcinoma (RCC) and chromophobe RCC. This case highlights the importance for practicing pathologists to recognize the rare co-occurrence of lymphovascular invasion and large intracytoplasmic vacuole-like spaces in renal oncocytoma. Other differential diagnoses may include emerging renal tumor entities, such as the recently-proposed eosinophilic vacuolated tumor.

scholarly journals Papillary renal cell carcinoma within a renal oncocytoma: Case report of very rare coexistence

2014 ◽  
Vol 8 (11-12) ◽  
pp. 928 ◽  
Author(s):  
Cevahir Özer ◽  
Mehmet Resit Gören ◽  
Tulga Egilmez ◽  
Nebil Bal
Keyword(s):  
Renal Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Radical Nephrectomy ◽  
Papillary Renal Cell Carcinoma ◽  
Renal Oncocytoma ◽  
Renal Neoplasms ◽  
Renal Oncocytomas ◽  
Papillary Rcc

Renal oncocytomas accounts for 3% to 9% of primary renal neoplasms. The coexistence of renal cell carcinoma (RCC) within the oncocytoma is extremely rare. We report the case of an asymptomatic 74-year-old man with papillary RCC within oncocytoma managed with left radical nephrectomy.

scholarly journals Henoch-Schönlein Purpura, a Rare Disease in Pregnancy

1970 ◽  
Vol 23 (2) ◽  
pp. 73-77
Author(s):  
Tabassum Parveen ◽  
Firoza Begum
Keyword(s):  
Rare Disease ◽  
Literature Search ◽  
Elective Caesarean Section ◽  
Laboratory Evaluation ◽  
Small Vessel Vasculitis ◽  
Bloody Stool ◽  
Henoch Schonlein Purpura ◽  
Schonlein Purpura ◽  
Henoch Schönlein Purpura ◽  
In Pregnancy

Introduction: Henoch-Schönlein purpura is an IgA-mediated small vessel vasculitis involving mainly skin, gastrointestinal system and kidneys. It is predominantly a disease of young children. Most common symptoms are rash (95-100%), sometimes necrotizing involving specially the legs, subcutaneous oedema (20-50%), abdominal pain and vomiting(85%), bloody stool and joint pain (60-80%) involving mainly the knees and ankles. Diagnosis is clinical and not based on laboratory evaluation. Its occurrence during pregnancy is exceptional. Materials & Methods: On literature search, till date only 17-18 cases of Henoch-Schönlein purpura in pregnancy were found. Case: Here we present a case report on this rare disease in pregnancy. A 39 year old lady, para 1+ 8 abortions, diagnosed as Henoch-Schönlein purpura at 24 weeks of gestation, treated with steroids and was cured almost completely. She was readmitted at 37 weeks of gestation with few purpuric rashes. Elective caesarean section was planned and a healthy male baby was delivered. But sub-total hysterectomy was needed for intractable bleeding from placental bed. Her post operative period was uneventful. Conclusion: Very few information we got on literature search on Henoch-Schönlein purpura in pregnancy. Corticosteroids and plasmapheresis have been practiced as treatment during pregnancy. If kidneys are unaffected, obstetrical prognosis is good. Key Words- Henoch-Schönlein Purpura; Pregnancy DOI: 10.3329/bjog.v23i2.4964 Bangladesh J Obstet Gynaecol, 2008; Vol. 23(2) : 73-77

scholarly journals Giant renal oncocytoma presenting with right flank pain and hematoma

2018 ◽  
Vol 5 (4) ◽  
pp. 13
Author(s):  
Robert Zakhia El Doueihi ◽  
Muhammad Ahmad Bulbul
Keyword(s):  
Chronic Kidney Disease ◽  
Renal Mass ◽  
Disease Patient ◽  
Flank Pain ◽  
Benign Tumors ◽  
Renal Oncocytoma ◽  
Renal Neoplasms ◽  
Radiological Imaging ◽  
Quadrant Pain ◽  
Renal Oncocytomas

Renal oncocytomas are benign tumors representing 3% to 7% of primary renal neoplasms. Oncocytomas are often asymptomatic, discovered incidentally on routine radiological imaging. We report a giant renal oncocytoma in a 68-year-old male with chronic kidney disease. Patient had right upper quadrant pain and hematoma. The mass was palpable on physical exam. CT scan showed a 16 cm × 14 cm right renal mass, consistent with renal cell carcinoma, no major adenopathy, no renal vein invasion. Right radical nephrectomy was performed and histological examination was consisted with oncocytoma.

Neurological manifestation in severe hypothyroidism in pregnancy

2020 ◽  
Vol 13 (12) ◽  
pp. e238069
Author(s):  
Aparna Sharma ◽  
Nilofar Noor ◽  
Vatsla Dadhwal
Keyword(s):  
Peripheral Neuropathy ◽  
Facial Palsy ◽  
Caesarean Delivery ◽  
Thyroid Stimulating Hormone ◽  
Neurological Manifestations ◽  
Second Trimester ◽  
Pituitary Hyperplasia ◽  
Very High ◽  
In Pregnancy

Neurological manifestations of hypothyroidism include peripheral neuropathy and pituitary hyperplasia. However, these associations are rarely encountered during pregnancy. We report a case of a known hypothyroid with very high thyroid stimulating hormone (TSH) values (512 μIU/mL) in the second trimester. At 24 weeks she developed facial palsy and pituitary hyperplasia which responded to a combination of steroids and thyroxine. She had caesarean delivery at 35 weeks and 3 days gestation in view of pre-eclampsia with severe features and was discharged on oral antihypertensives and thyroxine. On follow-up at 5 months, TSH normalised and pituitary hyperplasia showed a greater than 50% reduction in size. To our knowledge, this is the first reported case of facial palsy and pituitary hyperplasia associated with hypothyroidism during pregnancy.

Comparison of pregnancy outcomes after second trimester amniocentesis between procedures performed by experts and non-experts

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Tanapak Wisetmongkolchai ◽  
Fuanglada Tongprasert ◽  
Kasemsri Srisupundit ◽  
Suchaya Luewan ◽  
Kuntharee Traisrisilp ◽  
...  
Keyword(s):  
Pregnancy Outcomes ◽  
Loss Rate ◽  
Fetal Loss ◽  
Adverse Pregnancy Outcomes ◽  
Expert Group ◽  
Second Trimester ◽  
Single Institution ◽  
Adverse Pregnancy ◽  
In Pregnancy ◽  
Singleton Pregnancies

AbstractObjectivesTo compare the rate of fetal loss in pregnancy after second trimester amniocentesis between procedures performed by experts and non-experts and to assess other pregnancy complications as secondary outcomes.MethodsA retrospective cohort study was performed on singleton pregnancies that underwent mid-trimester amniocenteses in a single institution. The fetal loss rates of procedures performed by experts and non-experts were collected and analyzed. Other adverse pregnancy outcomes were also examined.ResultsIn total, 14,450 amniocenteses were performed during the study period. These included 11,357 (78.6%) procedures in the group expert operators and 3,093 (21.4%) procedures in the group non-expert operators. In the non-expert group, the fetal loss rate was slightly increased but not significantly (p=0.24).In addition, the higher number of spontaneous abortions was associated with blood-stained amniotic fluid sample (p<0.001; RR=9.28). Multiple needle insertions also increased in the non-expert group significantly. However, no difference in pregnancy outcomes was found between in single and multiple needle insertions.ConclusionsThe amniocentesis procedures performed by the non-experts was not increase the fetal loss rate. However, the other adverse pregnancy outcomes, including preterm birth, low birth weight and fetal growth restriction were significantly increased in the non-expert group.

scholarly journals Serum cystatin is not a marker of glomerular filtration rate in pregnancy

2009 ◽  
Vol 2 (3) ◽  
pp. 121-122 ◽  
Author(s):  
Kate Bramham ◽  
David Makanjuola ◽  
Wael Hussein ◽  
Debra Cafful ◽  
Hassan Shehata
Keyword(s):  
Glomerular Filtration Rate ◽  
Observational Study ◽  
Glomerular Filtration ◽  
Filtration Rate ◽  
Prospective Observational Study ◽  
Second Trimester ◽  
Third Trimester ◽  
Serum Cystatin ◽  
In Pregnancy

The role of cystatin C (Cys-C) as a marker of glomerular filtration rate (GFR) in pregnancy is undetermined. Measurements of Cys-C and creatinine (Cr) were taken at 14–17+6, 18–23+6, 27–31+6 weeks' gestation, at delivery and 2–6 weeks postpartum in a prospective observational study of 27 women. There was no difference between Cys-C levels in early and late second trimester, but they were significantly higher in early third trimester ( P < 0.001) than second trimester, despite no concurrent increase in Cr. Cys-C was also significantly higher at delivery than at all other times in pregnancy ( P < 0.001) and fell to postpartum values higher than second trimester measurements ( P < 0.01), but lower than delivery ( P<0.001). In conclusion, changes in Cys-C may be influenced by pregnancy-related changes in glomerular filtration and therefore we would advise against their use as a marker of GFR in pregnancy.

scholarly journals Malignant Mesenchymal Renal Tumor: A Rare Case of Primary Renal Fibrosarcoma

2013 ◽  
Vol 3 ◽  
pp. 52 ◽  
Author(s):  
Madanmohan Gupta ◽  
Nandini U. Bahri ◽  
Pankaj Watal ◽  
Shilpa L. Chudasama ◽  
Swetang G. Brahmbhatt ◽  
...  
Keyword(s):  
Rare Case ◽  
Renal Mass ◽  
Renal Tumor ◽  
Abdominal Discomfort ◽  
Renal Neoplasms ◽  
Cross Sectional ◽  
Elderly Female ◽  
Mesenchymal Neoplasms ◽  
Cross Sectional Imaging ◽  
Rare Group

Malignant mesenchymal neoplasms of kidney constitute a rare group of tumors. Primary fibrosarcoma of kidney is an extremely rare subtype of primary malignant mesenchymal renal neoplasms. An elderly female presented with a gradually increasing abdominal lump and mild abdominal discomfort. On cross-sectional imaging, the lesion showed features suggestive of an atypical renal mass not conforming to either ball or bean type growth pattern. The mass was surgically removed and on histopathological and immunohistological investigations diagnosed to be primary renal fibrosarcoma.

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