scholarly journals Randomized Controlled Trial Evaluating Aerobic Training and Common Sport-Related Concussion Outcomes in Healthy Participants

2018 ◽  
Vol 53 (12) ◽  
pp. 1156-1165
Author(s):  
Elizabeth F. Teel ◽  
Johna K. Register-Mihalik ◽  
Lawrence Gregory Appelbaum ◽  
Claudio L. Battaglini ◽  
Kevin A. Carneiro ◽  
...  
Keyword(s):  
Aerobic Exercise ◽  
Symptom Score ◽  
Aerobic Training ◽  
Intervention Group ◽  
Assessment Tools ◽  
Total Symptom Score ◽  
Exercise Interventions ◽  
Randomized Controlled ◽  
Healthy Participants ◽  
Active Training

Context Aerobic exercise interventions are increasingly being prescribed for concussion rehabilitation, but whether aerobic training protocols influence clinical concussion diagnosis and management assessments is unknown. Objective To investigate the effects of a brief aerobic exercise intervention on clinical concussion outcomes in healthy, active participants. Design Randomized controlled clinical trial. Setting Laboratory. Patients or Other Participants Healthy (uninjured) participants (n = 40) who exercised ≥3 times/week. Intervention(s) Participants were randomized into the acute concussion therapy intervention (ACTIVE) training or nontraining group. All participants completed symptom, cognitive, balance, and vision assessments during 2 test sessions approximately 14 days apart. Participants randomized to ACTIVE training completed six 30-minute exercise sessions that progressed from 60% to 80% of individualized maximal oxygen consumption (V˙o2max) across test sessions, while the nontraining group received no intervention. Main Outcome Measure(s) The CNS Vital Signs standardized scores, Vestibular/Ocular Motor Screening near-point convergence distance (cm), and Graded Symptom Checklist, Balance Error Scoring System, and Standardized Assessment of Concussion total scores. Results An interaction effect was found for total symptom score (P = .01); the intervention group had improved symptom scores between sessions (session 1: 5.1 ± 5.8; session 2: 1.9 ± 3.6). Cognitive flexibility, executive functioning, reasoning, and total symptom score outcomes were better but composite memory, verbal memory, and near-point convergence distance scores were worse at the second session (all P values < .05). However, few changes exceeded the 80% reliable change indices calculated for this study, and effect sizes were generally small to negligible. Conclusions A brief aerobic training protocol had few meaningful effects on clinical concussion assessment in healthy participants, suggesting that current concussion-diagnostic and -assessment tools remain clinically stable in response to aerobic exercise training. This provides normative data for future researchers, who should further evaluate the effect of ACTIVE training on clinical outcomes among concussed populations. Trial Registration Number ClinicalTrials.gov: NCT02872480

A Randomized Controlled Trial Investigating the Feasibility and Adherence to an Aerobic Training Program in Healthy Individuals

2019 ◽  
Vol 28 (7) ◽  
pp. 692-698
Author(s):  
Elizabeth F. Teel ◽  
Stephen W. Marshall ◽  
L. Gregory Appelbaum ◽  
Claudio L. Battaglini ◽  
Kevin A. Carneiro ◽  
...  
Keyword(s):  
Physical Activity ◽  
Randomized Controlled Trial ◽  
University Students ◽  
Aerobic Exercise ◽  
Training Program ◽  
Aerobic Training ◽  
Controlled Trial ◽  
Phase 1 ◽  
Randomized Controlled ◽  
Active Training

Context:Concussion management is moving from passive rest strategies to active interventions, including aerobic exercise therapy. Little information is available regarding the feasibility and adherence of these programs.Objectives:To determine whether an aerobic exercise training program intended for rehabilitation in people with concussion is feasible. Healthy, nonconcussed subjects were studied in this phase 1 trial.Design:Phase 1 parallel-group, randomized controlled trial in a sample of healthy (nonconcussed), recreationally active university students.Setting:Laboratory.Patients:40 healthy university students.Methods:Participants were equally randomized to acute concussion therapy intervention (ACTIVE) training or nontraining groups. All participants completed maximal cardiopulmonary exercise tests on a stationary cycle ergometer at 2 test sessions approximately 14 days apart. During this 2-week study period, ACTIVE training participants completed six 30-minute cycling sessions, progressing from 60% to 80% of the participant’s individualized maximal oxygen consumption. A subset of participants (NACTIVE = 12, Nnontraining = 11) wore physical activity monitors throughout the 2-week study period.Main Outcomes Measures:Study protocol and randomization effectiveness, exercise safety and adherence, and progressive intensity of the ACTIVE training procedures.Results:No adverse events occurred during any exercise sessions. Twelve ACTIVE training participants (60%) completed all training sessions, and every participant completed at least 4 sessions. Heart rate increased throughout the training period (P < .001), but symptom changes and training adherence remained stable despite the progressively increasing workload. ACTIVE training participants completed approximately 30 additional minutes of physical activity on training sessions days, although that was not statistically significant (P = .20).Conclusions:University-aged students were adherent to the ACTIVE training protocol. Future research should investigate the safety and feasibility of aerobic training programs in acutely concussed individuals to determine their appropriateness as a clinical rehabilitation strategy.

Moderators of Maintained Increase in Aerobic Exercise Among Aging Men and Women in a 4-Year Randomized Controlled Trial: The DR’s EXTRA Study

2015 ◽  
Vol 12 (11) ◽  
pp. 1477-1484 ◽  
Author(s):  
Leena Hakola ◽  
Kai Savonen ◽  
Pirjo Komulainen ◽  
Maija Hassinen ◽  
Rainer Rauramaa ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Aerobic Exercise ◽  
Controlled Trial ◽  
Intervention Group ◽  
Exercise Group ◽  
Control Group ◽  
Older Individuals ◽  
Men And Women ◽  
Exercise Interventions ◽  
Randomized Controlled

Background:Little is known about factors that modify the effectiveness of exercise interventions in increasing exercise. We aimed to identify moderators of the effectiveness of aerobic exercise intervention in maintaining increased aerobic exercise among older individuals.Methods:The participants of a 4-year randomized controlled trial were a population sample of 1410 men and women aged 57 to 78 years. The aerobic exercise group included 185 individuals and the control group included 169 individuals who reported low aerobic exercise at baseline. Maintained increase in aerobic exercise was defined as at least 60-minute increase in moderate-to-heavy aerobic exercise per week from baseline to 2- and 4-year assessments.Results:Individuals in the aerobic exercise group were 2.5 (95% CI 1.5 to 3.9) times more likely to maintain increased aerobic exercise than those in the control group. Individuals aged < 68.5 years but not older individuals succeeded in maintaining increased aerobic exercise in the intervention group (P = .02 for interaction). Individuals who were past smokers (P = .02 for interaction), were working (P = .05 for interaction), or had symptoms of depression (P = .05 for interaction) succeeded better in maintaining increased aerobic exercise in the intervention group than other individuals.Conclusions:These findings help in more precise targeting of future exercise interventions among older individuals.

The Effects of Quadriceps Kinesio Taping on Aerobic and Anaerobic Exercise Performance in Healthy Participants: A Randomized Controlled Study

2016 ◽  
Vol 21 (2) ◽  
pp. 32-38 ◽  
Author(s):  
Neslihan Duruturk ◽  
Nihan Ozunlu Pekyavas ◽  
Atakan Yρlmaz ◽  
Metin Karatas
Keyword(s):  
Aerobic Exercise ◽  
Exercise Capacity ◽  
Exercise Performance ◽  
Athletic Performance ◽  
Quadriceps Muscle ◽  
Anaerobic Exercise ◽  
Randomized Controlled ◽  
Aerobic Exercise Capacity ◽  
Aerobic And Anaerobic ◽  
Healthy Participants

Objective:Aerobic and anaerobic exercise capacities are important components of athletic performance. The use of Kinesio Taping® (KT) as a supplementary treatment in athletic settings has increased in the recent years. KT can facilitate muscle contraction, which may be useful for improving performance. The purpose of this study was to determine whether the application of KT to the quadriceps muscle has any effect on anaerobic and aerobic performance in young healthy individuals.Design:Randomized, controlled, double-blind clinical study.Setting:Baskent University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation.Patients:Thirty-two healthy male participants were randomly assigned to either the KT group or a sham KT (SKT) group.Interventions:The KT muscle facilitation technique was applied to the quadriceps muscle bilaterally and measurements were taken 45 min later to ensure full adhesion.Main Outcome Measures:The Wingate cycle ergometer test was used to assess peak anaerobic power (peak AnP, in Watts) and exercise capacity (Watt/kg), while the 6-minute walk test (6MWT) was used to assess aerobic exercise capacity of the participants. Comparisons between groups were performed using the nonparametric Mann-Whitney U test, while those between baseline and posttaping used the nonparametric Wilcoxon test.Results:No significant difference was found between the two groups in the aerobic or anaerobic test parameters (p > .05). Within the groups, a significant improvement in time factors in peak AnP (929.7 2 ± 184.37 W to 1043.49 ± 224.42 W) was found only in the KT group (p = .028) and no other parameter was significantly different (p > .05).Conclusions:KT applied to the quadriceps muscle can positively improve anaerobic exercise performance and athletic performance capacity. However, KT did not affect aerobic capacity. Further research is needed to show that KT can improve and support anaerobic and aerobic exercise capacity in healthy participants or athletes.

scholarly journals Frailty Intervention through Nutrition Education and Exercise (FINE). A Health Promotion Intervention to Prevent Frailty and Improve Frailty Status among Pre-Frail Elderly—A Study Protocol of a Cluster Randomized Controlled Trial

Nutrients ◽  
2020 ◽  
Vol 12 (9) ◽  
pp. 2758 ◽  
Author(s):  
Nurul Izzati Mohd Suffian ◽  
Siti Nur ‘Asyura Adznam ◽  
Hazizi Abu Saad ◽  
Yoke Mun Chan ◽  
Zuriati Ibrahim ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Frail Elderly ◽  
Controlled Trial ◽  
Intervention Group ◽  
Adverse Outcomes ◽  
Cluster Randomized Controlled Trial ◽  
Nutritional Education ◽  
Exercise Interventions ◽  
Randomized Controlled ◽  
Cluster Randomized

The ageing process has been associated with various geriatric issues including frailty. Without early prevention, frailty may cause multiple adverse outcomes. However, it potentially may be reversed with appropriate interventions. The aim of the study is to assess the effectiveness of nutritional education and exercise intervention to prevent frailty among the elderly. A 3-month, single-blind, two-armed, cluster randomized controlled trial of the frailty intervention program among Malaysian pre-frail elderly will be conducted. A minimum of total 60 eligible respondents from 8 clusters (flats) of Program Perumahan Rakyat (PPR) flats will be recruited and randomized to the intervention and control arm. The intervention group will receive a nutritional education and a low to moderate multi-component exercise program. To date, this is the first intervention study that specifically targets both the degree of frailty and an improvement in the outcomes of frailty using both nutritional education and exercise interventions among Malaysian pre-frail elderly. If the study is shown to be effective, there are major potential benefits to older population in terms of preventing transition to frailty. The findings from this trial will potentially provide valuable evidence and serve as a model for similar future interventions designed for elderly Malaysians in the community.

Continuous versus intermittent aerobic exercise in the improvement of quality of life for women with polycystic ovary syndrome: A randomized controlled trial

2019 ◽  
pp. 135910531986980 ◽  
Author(s):  
Victor Barbosa Ribeiro ◽  
Iris Palma Lopes ◽  
Rosana Maria dos Reis ◽  
Rafael Costa Silva ◽  
Maria Célia Mendes ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Polycystic Ovary Syndrome ◽  
Aerobic Exercise ◽  
Aerobic Training ◽  
Polycystic Ovary ◽  
Control Group ◽  
Ovary Syndrome ◽  
Testosterone Levels ◽  
Randomized Controlled

Polycystic ovary syndrome predisposes alterations which contribute to the reduction of quality of life. This randomized controlled clinical trial study was to evaluate the effect of two protocols of aerobic exercise on quality of life in women with polycystic ovary syndrome. Women were allocated to three groups: continuous aerobic training ( n = 28), intermittent aerobic training ( n = 29), and control group (no training; n = 30). Testosterone levels, body composition indices, and quality of life were assessed at baseline and after 16 weeks of intervention. Both protocols were effective to improve testosterone levels, anthropometric indices, and quality of life in polycystic ovary syndrome women. Thus, these protocols should be included in the clinical environment to improve clinical parameters psychological, biological and social health to this population.

Randomized Controlled Trial of Resistance or Aerobic Exercise in Men Receiving Radiation Therapy for Prostate Cancer

2009 ◽  
Vol 27 (3) ◽  
pp. 344-351 ◽  
Author(s):  
Roanne J. Segal ◽  
Robert D. Reid ◽  
Kerry S. Courneya ◽  
Ronald J. Sigal ◽  
Glen P. Kenny ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Randomized Controlled Trial ◽  
Physical Fitness ◽  
Aerobic Exercise ◽  
Usual Care ◽  
Body Fat ◽  
Aerobic Training ◽  
Controlled Trial ◽  
Short Term ◽  
Randomized Controlled

Purpose Radiotherapy for prostate cancer (PCa) may cause unfavorable changes in fatigue, quality of life (QOL), and physical fitness. We report results from the Prostate Cancer Radiotherapy and Exercise Versus Normal Treatment study examining the effects of 24 weeks of resistance or aerobic training versus usual care on fatigue, QOL, physical fitness, body composition, prostate-specific antigen, testosterone, hemoglobin, and lipid levels in men with PCa receiving radiotherapy. Patients and Methods Between 2003 and 2006, we conducted a randomized controlled trial in Ottawa, Canada, where 121 PCa patients initiating radiotherapy with or without androgen deprivation therapy were randomly assigned to usual care (n = 41), resistance (n = 40), or aerobic exercise (n = 40) for 24 weeks. Our primary end point was fatigue assessed by the Functional Assessment of Cancer Therapy–Fatigue scale. Results The follow-up assessment rate for our primary end point of fatigue was 92.6%. Median adherence to prescribed exercise was 85.5%. Mixed-model repeated measures analyses indicated both resistance (P =.010) and aerobic exercise (P = .004) mitigated fatigue over the short term. Resistance exercise also produced longer-term improvements (P = .002). Compared with usual care, resistance training improved QOL (P = .015), aerobic fitness (P = .041), upper- (P < .001) and lower-body (P < .001) strength, and triglycerides (P = .036), while preventing an increase in body fat (P = .049). Aerobic training also improved fitness (P = .052). One serious adverse event occurred in the group that performed aerobic exercise. Conclusion In the short term, both resistance and aerobic exercise mitigated fatigue in men with PCa receiving radiotherapy. Resistance exercise generated longer-term improvements and additional benefits for QOL, strength, triglycerides, and body fat.

scholarly journals Systematic Review and Meta-Analysis of Randomized, Controlled Trials on Preoperative Physical Exercise Interventions in Patients with Non-Small-Cell Lung Cancer

Cancers ◽  
2019 ◽  
Vol 11 (7) ◽  
pp. 944 ◽  
Author(s):  
Ilem D. Rosero ◽  
Robinson Ramírez-Vélez ◽  
Alejando Lucia ◽  
Nicolas Martínez-Velilla ◽  
Alejandro Santos-Lozano ◽  
...  
Keyword(s):  
Aerobic Training ◽  
Meta Analysis ◽  
Small Cell ◽  
Inspiratory Muscle ◽  
Inspiratory Muscle Training ◽  
Small Cell Lung ◽  
Muscle Training ◽  
Exercise Interventions ◽  
Randomized Controlled ◽  
Preoperative Exercise

Preoperative physical exercise protocols prior to cancer surgery increased in popularity over recent years; however, the beneficial effect of such protocols is not well established, with conflicting results reported. We conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) to assess the effects of different modalities or combinations of preoperative exercise interventions and/or prehabilitation multicomponent training in patients with non-small-cell lung cancer (NSCLC) after surgery on the outcomes related to functional capacity, mental wellness and medical care. We searched in OVID Embase, Pubmed, Cochrane Library, CINAHL, Scopus, and Web of Science. Characteristics of studies and program results and outcome data were extracted. Changes between the intervention and control groups, from baseline to follow-up (standardized mean difference (SMD) or relative risk (RR) with 95% confidence interval (CI) for each intervention was pooled using weighted random-effects models). A total of 676 participants from 10 RCTs were included in the final analysis (aerobic training + inspiratory muscle training, n = 5; aerobic training + strength training + inspiratory muscle training, n = 2; aerobic training + strength training, n = 1; multicomponent training, n = 1; aerobic training alone, n = 1). The results showed intervention-induced improvement in walking endurance (SMD = 0.27; 95% CI, 0.11 to 0.44; I2 = 0.0%), peak exercise capacity (SMD = 0.78; 95% CI, 0.35 to 1.21; I2 = 76.7%), dyspnoea (SMD = −0.30; 95% CI, −0.51 to −0.10; I2 = 0.0%), risk of hospitalization (SMD = −0.58; 95% CI, −0.97 to −0.20; I2 = 70.7%), and postoperative pulmonary complications (relative risk (RR) = 0.50; 95% CI, 0.39 to 0.66; I2 = 0.0%). For the functional capacity and medical care parameters, preoperative combined aerobic, resistance, and inspiratory muscle training was shown to be effective if comprising one to four weeks, performing 1–3 sessions per week, with moderate intensity (50% for endurance capacity). Further studies with larger samples and higher methodological quality are needed to clarify the potential benefits of preoperative exercise training for patients with NSCLC.

scholarly journals Effects of Moderate Aerobic Training on Cognitive Performance and Dyslipidemia in Sedentary Older Adults

2020 ◽  
Author(s):  
Ahmad H. Alghadir ◽  
Sami Gabr
Keyword(s):  
Physical Activity ◽  
Older Adults ◽  
Aerobic Exercise ◽  
Lipid Profile ◽  
Cognitive Performance ◽  
Aerobic Fitness ◽  
Aerobic Training ◽  
Control Group ◽  
Exercise Interventions ◽  
Lipoprotein A

Abstract Background: The present study was designed to evaluate the effects of 24 weeks of moderate aerobic exercise on the levels of lipids and lipoprotein; Lipo(a) markers and its association with cognitive performance in healthy older adults. Methods: A total of 150 healthy subjects (100 males, 50 females; age range; 65-95Yrs) were recruited for this study. Based up on LOTCA test score, subjects were classified randomly into two groups control group (n= 50) and cognitive impairment group (n=100).Cognitive functioning, Leisure-time physical activity (LTPA), lipid profile; total cholesterol, TG, HDL-c, LDL-C, and Lipo(a) were assessed at baseline and post- 24 week aerobic exercise interventions using LOTCA battery, pre validated PA questionnaire, colorimetric and immunoassay techniques respectively. Results. Significant improvements in the cognitive function and modulation in lipid profile and lipoprotein (a) markers were reported in all older subjects following 24 week of moderate exercise. LOTCA-7-sets scores showed a significant correlation with physical activity status and the regulation of lipids and lipo(a) markers. Physically active persons showed a higher cognitive performance along with reduction in the levels of T-Cholest., TG, LDL-C, Lipo(a) , and increase in the levels of HDL-C and aerobic fitness VO2max compared with sedentary participants. Cognitive performance correlated positively with the increase in aerobic fitness, HDL-C, and negatively with T-Cholest.,TG, LDL-C, Lipo(a) respectively. However, a significant increase, in the improvement of motor praxis, vasomotor organization, thinking operations, attention and concentration was reported among older adults. Conclusions: The data concluded that supervised moderate aerobic training for 24 weeks plays a positive significant effect in improving cognitive functions via modulating lipid profile and lipoprotein (a) of older adults.

scholarly journals Home Based Aerobic Training and the Changes in Adipsin Levels and Visceral Adiposity Index (VAI) in Women with Polycystic Ovary Syndrome

2020 ◽  
Vol 6 (2) ◽  
Author(s):  
Nahid Mohammadi Javid ◽  
Nasser Behpoor ◽  
Vahid Tadibi
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Aerobic Exercise ◽  
Aerobic Training ◽  
Polycystic Ovary ◽  
Intervention Group ◽  
Visceral Adiposity ◽  
Visceral Adiposity Index ◽  
Ovary Syndrome ◽  
Adiposity Index ◽  
Home Based

Background: Polycystic ovary syndrome (PCOS) is prevalent in 5% - 8% of women of reproductive age and is one of the most important causes of infertility. Objectives: The aim of this study was to investigate the effect of home-made aerobic activity on the level of changes in adipsin levels and visceral adiposity (VAI) in woman patients with chronic polycystic ovary syndrome in Kermanshah city. Materials and Methods: This study was carried out among 24 women with PCOS in 2017. The samples were 12 people in the intervention group and 12 people in the control group (referred to Kermanshah health centers). The intervention group then performed home-based aerobic training for 16 weeks. Serum levels of adiposity and visceral adiposity were measured before and after the exercise program through blood sampling. SPSS V.22 software was used for data analysis and t-test with independent sample and paired t-test. Results: There was a significant difference in the visceral adiposity index (VAI) after 16 weeks of aerobic exercise in the intervention group (P = 0.014). However, adipsin level changes were not statistically significant in the control and control groups. (P = 0.097). Conclusion: Aerobic exercise under house supervision has a favorable effect on the visceral adiposity index in women with PCOS and can be recommended as a safe treatment for these patients.

scholarly journals ENDOCRINOLOGY AND ADOLESCENCE: Aerobic exercise reduces insulin resistance markers in obese youth: a meta-analysis of randomized controlled trials

2014 ◽  
Vol 171 (4) ◽  
pp. R163-R171 ◽  
Author(s):  
Antonio García-Hermoso ◽  
Jose M Saavedra ◽  
Yolanda Escalante ◽  
Mairena Sánchez-López ◽  
Vicente Martínez-Vizcaíno
Keyword(s):  
Insulin Resistance ◽  
Aerobic Exercise ◽  
Body Fat ◽  
Meta Analysis ◽  
Controlled Trials ◽  
Exercise Interventions ◽  
Randomized Controlled ◽  
Percentage Of Body Fat ◽  
Obese Youth ◽  
Resistance Markers

ObjectiveThe purpose of this meta-analysis was to examine the evidence for the effectiveness of aerobic exercise interventions on reducing insulin resistance markers in obese children and/or adolescents. A secondary outcome was change in percentage of body fat.MethodsA computerized search was made from seven databases: CINAHL, Cochrane Central Register of Controlled Trials, EMBASE, ERIC, MEDLINE, PsycINFO, and Science Citation Index. The analysis was restricted to randomized controlled trials that examined the effect of aerobic exercise on insulin resistance markers in obese youth. Two independent reviewers screened studies and extracted data. Effect sizes (ES) and 95% confidence interval (CI) were calculated, and the heterogeneity of the studies was estimated using Cochran'sQ-statistic.ResultsNine studies were selected for meta-analysis as they fulfilled the inclusion criteria (n=367). Aerobic exercise interventions resulted in decreases in fasting glucose (ES=−0.39; low heterogeneity) and insulin (ES=−0.40; low heterogeneity) and in percentage of body fat (ES=−0.35; low heterogeneity). These improvements were specifically accentuated in adolescents (only in fasting insulin), or through programs lasting more than 12 weeks, three sessions per week, and over 60 min of aerobic exercise per session.ConclusionsThis meta-analysis provides insights into the effectiveness of aerobic exercise interventions on insulin resistance markers in the obese youth population.

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