scholarly journals Clinical-Epidemiological Profile of Influenza A H1N1 Cases at a Tertiary Care Institute of India

2012 ◽  
Vol 37 (4) ◽  
pp. 232 ◽  
Author(s):  
Vijaydeep Siddharth ◽  
Vineet Goyal ◽  
VipinKumar Koushal
Author(s):  
Yogesh Kumar Singhal ◽  
Nitin Kothari

Background: Influenza, commonly referred to as the flu, is an infectious disease caused by RNA viruses of the family Orthomyxoviridae (the influenza viruses). Swine flu cases resurfaced in month of January 2015 in Southern region of India which are continuation of pandemic 2009. Aim of this study is to summaries the clinical and epidemiological factors associated with swine flu as well as to estimate the burden of Influenza A H1N1 (Swine Flu) cases.Methods: A complete data of all the patients visiting swine flu OPDs, swine flu wards and ICU were maintained for year 2015. Each patient visiting either the swine flu OPD or the swine flu ward, who was suspected clinically to be H1N1 positive were tested for real time PCR.Results: Out of 1247 samples tested for rt-PCR 491 (39.37%) cases were identified as positive for H1N1. Maximum swine positivity was seen in the age group of 16-30 year i.e. 147 (29.94%). Overall swine positivity was significantly (<0.001) higher in females than male and extremely statistically significant (p<0.0001) higher in rural areas than urban. Cough was the most common clinical symptoms affecting 469(95.52%) patients followed by fever (92.26%) and breathlessness 402(81.87%).Conclusions: Our study will help epidemiologist and clinician to identify epidemiological factors and clinical picture of swine flu.


Author(s):  
Anita A. Paritekar ◽  
Mahendra V. Bansode ◽  
Anushka K. Waikar ◽  
Rohidas T. Borse

Background: The onset of winter of 2014-2015 saw an alarming spurt in influenza A (H1N1) pdm 09 leading to a significant mortality. H1N1 primarily affects the very young, elderly, pregnancy and those patients with comorbidities. But the epidemiologic hallmark of pandemic influenza is its "pandemic signature " meaning most early mortalities are among young healthy adults.Methods: To study clinical profile, premorbid conditions and radiological features of Category C H1N1 proven by RTPCR retrospectively from hospital records from Jan 2015 to Dec 2015 at Tertiary Care Centre.Results: Total 108 cases RT PCR proven category C H1N1 studied from hospital records. 43 were males and 65 females. The mean age group was 50 years for males and 40 for females. Common symptoms were fever, cough, dyspnoea with pre-morbid illness like hypertension, diabetes mellitus, pregnancy, cancer and immune compromised with pulmonary tuberculosis. Radiologically there was lower zone involvement common in live patients and reticulonodular was common in death cases.Conclusions: In current study young to middle age group was commonly affected. Pre-morbid conditions, more than two risk factors and late referral were the most common findings in death cases.


2020 ◽  
Vol 31 (4) ◽  
pp. 759
Author(s):  
Elayaperumal Indhumathi ◽  
Vamsi Krishna Makkena ◽  
Varun Mamidi ◽  
Varadharajan Jayaprakash ◽  
Matcha Jayakumar

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