scholarly journals Respiratory viruses in returning Hajj & Umrah pilgrims with acute respiratory illness in 2014-2015

2018 ◽  
Vol 148 (3) ◽  
pp. 329 ◽  
Author(s):  
ParvaizA Koul ◽  
Hyder Mir ◽  
Siddhartha Saha ◽  
MandeepS Chadha ◽  
Varsha Potdar ◽  
...  
2019 ◽  
Vol 40 (8) ◽  
pp. 889-896 ◽  
Author(s):  
Lili Jiang ◽  
Allison McGeer ◽  
Shelly McNeil ◽  
Kevin Katz ◽  
Mark Loeb ◽  
...  

AbstractBackground:Healthcare workers (HCWs) are at risk of acquiring and transmitting respiratory viruses while working in healthcare settings.Objectives:To investigate the incidence of and factors associated with HCWs working during an acute respiratory illness (ARI).Methods:HCWs from 9 Canadian hospitals were prospectively enrolled in active surveillance for ARI during the 2010–2011 to 2013–2014 influenza seasons. Daily illness diaries during ARI episodes collected information on symptoms and work attendance.Results:At least 1 ARI episode was reported by 50.4% of participants each study season. Overall, 94.6% of ill individuals reported working at least 1 day while symptomatic, resulting in an estimated 1.9 days of working while symptomatic and 0.5 days of absence during an ARI per participant season. In multivariable analysis, the adjusted relative risk of working while symptomatic was higher for physicians and lower for nurses relative to other HCWs. Participants were more likely to work if symptoms were less severe and on the illness onset date compared to subsequent days. The most cited reason for working while symptomatic was that symptoms were mild and the HCW felt well enough to work (67%). Participants were more likely to state that they could not afford to stay home if they did not have paid sick leave and were younger.Conclusions:HCWs worked during most episodes of ARI, most often because their symptoms were mild. Further data are needed to understand how best to balance the costs and risks of absenteeism versus those associated with working while ill.


2015 ◽  
Vol 9 (6) ◽  
pp. 287-292 ◽  
Author(s):  
Yazmin Moreno‐Valencia ◽  
Victor A. Hernandez‐Hernandez ◽  
Jose A. I. Romero‐Espinoza ◽  
Rodrigo H. Coronel‐Tellez ◽  
Manuel Castillejos‐Lopez ◽  
...  

BMJ Open ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. e040612
Author(s):  
Sky Vanderburg ◽  
Gaya Wijayaratne ◽  
Nayomi Danthanarayana ◽  
Jude Jayamaha ◽  
Bhagya Piyasiri ◽  
...  

ObjectivesTo determine aetiology of illness among children and adults presenting during outbreak of severe respiratory illness in Southern Province, Sri Lanka, in 2018.DesignProspective, cross-sectional study.Setting1600-bed, public, tertiary care hospital in Southern Province, Sri Lanka.Participants410 consecutive patients, including 371 children and 39 adults, who were admitted with suspected viral pneumonia (passive surveillance) or who met case definition for acute respiratory illness (active surveillance) in May to June 2018.ResultsWe found that cocirculation of influenza A (22.6% of cases), respiratory syncytial virus (27.8%) and adenovirus (AdV) (30.7%; type B3) was responsible for the outbreak. Mortality was noted in 4.5% of paediatric cases identified during active surveillance. Virus type and viral coinfection were not significantly associated with mortality.ConclusionsThis is the first report of intense cocirculation of multiple respiratory viruses as a cause of an outbreak of severe acute respiratory illness in Sri Lanka, and the first time that AdV has been documented as a cause of a respiratory outbreak in the country. Our results emphasise the need for continued vigilance in surveying for known and emerging respiratory viruses in the tropics.


Author(s):  
Michael L Jackson ◽  
Lea Starita ◽  
Erika Kiniry ◽  
C Hallie Phillips ◽  
Stacie Wellwood ◽  
...  

Abstract Background While multiple respiratory viruses circulate in humans, few studies have compared the incidence of different viruses across the life course. We estimated the incidence of outpatient illness due to 12 different viruses during November 2018 through April 2019 in a fully enumerated population. Methods We conducted active surveillance for ambulatory care visits for acute respiratory illness (ARI) among members of Kaiser Permanente Washington (KPWA). Enrolled patients provided respiratory swab specimens which were tested for 12 respiratory viruses using RT-PCR. We estimated the cumulative incidence of infection due to each virus overall and by age group. Results The KPWA population under surveillance included 202,562 individuals, of whom 2,767 (1.4%) were enrolled in the study. Influenza A(H3N2) was the most commonly detected virus, with an overall incidence 21 medically attended illnesses per 1,000 population; the next most common viruses were influenza A(H1N1) (18 per 1,000), coronaviruses (13 per 1,000), respiratory syncytial virus (RSV, 13 per 1,000), and rhinovirus (9 per 1,000). RSV was the most common cause of medically attended ARI among children aged 1-4 years; coronaviruses were the most common among adults aged ≥65 years. Conclusions Consistent with other studies focused on single viruses, we found that influenza and RSV were major causes of acute respiratory illness in persons of all ages. In comparison, coronaviruses and rhinovirus were also important pathogens. Prior to the emergence of SARS-CoV-2, coronaviruses were the second-most common cause of medically attended ARI during the 2018/19 influenza season.


Thorax ◽  
2010 ◽  
Vol 65 (7) ◽  
pp. 639-644 ◽  
Author(s):  
K. C. Sumino ◽  
M. J. Walter ◽  
C. L. Mikols ◽  
S. A. Thompson ◽  
M. Gaudreault-Keener ◽  
...  

2018 ◽  
Vol 218 (4) ◽  
pp. 528-535 ◽  
Author(s):  
Anne M Hause ◽  
Vasanthi Avadhanula ◽  
Maurizio L Maccato ◽  
Phillip M Pinell ◽  
Nanette Bond ◽  
...  

Abstract Background Other than influenza, little is known about the consequences of viral acute respiratory illness (ARI) on pregnant women and fetuses. Our objectives were to determine the frequency of ARI due to respiratory viruses and the associated clinical outcomes during pregnancy. Methods Pregnant women in their second or third trimester were enrolled if they reported having symptoms of ARI or were healthy within the preceding 2 weeks. Nasopharyngeal secretions were evaluated for respiratory viruses by molecular diagnostic assays. Clinical outcomes were evaluated at enrollment and via a follow-up telephone-based questionnaire 2 weeks later. Results There were 155 pregnant participants, with 81 ARI cases and 91 healthy controls. Acute lower respiratory tract illness (ALRTI) was identified in 29 cases (36%). Human rhinovirus (HRV), respiratory syncytial virus (RSV), and influenza virus accounted for 75% of virus-positive cases of ALRTI. Cases with ALRTI often reported a longer duration of illness, history of allergies, symptoms of wheezing, shortness of breath, or chest pain, and use of prescription medication. Two cases with ALRTI reported decreased fetal movement; a third case with ALRTI was hospitalized. Conclusions In over one third of ARI cases, participants had symptoms consistent with ALRTI. Infection with HRV, RSV, or influenza virus was commonly detected in patients with ALRTI. Viral ALRTI during pregnancy appears to be common and is associated with significant morbidity.


2018 ◽  
Vol 4 (2) ◽  
pp. 18
Author(s):  
Wen-Kuan Liu ◽  
Qian Liu ◽  
De-Hui Chen ◽  
Wei-Ping Tan ◽  
Shu-Yan Qiu ◽  
...  

Background: Respiratory virus infections often cause a wide spectrum of symptoms including gastrointestinal presentations (GP). The epidemiology of respiratory viruses in patients with GP needs to be better described.Methods: Throat swabs were collected and tested for 15 respiratory viruses from pediatric patients (≤14 years old) with acute respiratory illness in Guangzhou over a 3-year period. The features of respiratory virus infections were analyzed among those with GP.Results: Of 4,242 patients enrolled, 1,223 (28.8%) had GP. Among those, 647 (52.9%) were positive with one or more of the 15 tested respiratory viruses. The most frequently detected viruses were respiratory syncytial virus (RSV) (21.1%, 258), enterovirus (EV) (10.1%, 124), influenza A virus (infA) (7.8%, 95), adenovirus (ADV) (5%, 61), human metapneumovirus (HMPV) (4.1%, 50), and human bocavirus (HBoV) (3.5%, 43). More RSV (p = .001) and EV (P<0.001) infections were found in patients with GP than in patients without GP. 734 (60.0%) patients with GP presented with “Poor appetite”, 480 (39.2%) with “Vomiting”, 301 (24.6%) with “Diarrhea” and 73 (6.0%) with “Stomachache”. Significant differences in the virus positivity rate were found for RSV (p < .001), EV (p = .002) and PIV3 (p = .037). 90.6% (1,108/1,223) of patients with GP were under 5 years old. Among different age groups, significant differences in the virus positivity rate were found for infA (p = .005), influenza B virus (infB) (p = .006), RSV (p < .001), parainfluenza virus type 3 (PIV3) (p = .019), ADV (P<0.001), and HBoV (p = .009). RSV was mostly detected in patients under 2 years old (90.3%, 233/258) with frequency declining with age, while frequency of infA and infB increased with age. ADV, HBoV, and PIV3 reached their highest peaks in the age groups of 6-10 years old (11%), 7-12 months (8%) and 4–6 months (5.8%), respectively. In general, sample positivity rates in patients with GP increased when seasons changed. RSV, EV, infA, ADV, HMPV, and HBoV formed the bulk of the positive samples.Conclusions: In this study, the epidemiology of respiratory virus infections in patients with GP was analyzed. This information increases our understanding of respiratory virus infections and may help in clinical diagnosis of these viruses.


PEDIATRICS ◽  
2016 ◽  
Vol 137 (Supplement 3) ◽  
pp. 382A-382A
Author(s):  
Michelle Eckerle ◽  
Noel Mumba ◽  
Melissa Miller ◽  
Mark Steinhoff

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