scholarly journals Comparison the oral premedication of midazolam, dexmedetomidine, and melatonin for children’s sedation and ease of separation from parents before anesthesia

2020 ◽  
Vol 15 (3) ◽  
pp. 231
Author(s):  
Hesameddin Modir ◽  
Bijan Yazdi ◽  
Mahsa Mombeini ◽  
Alireza Kamali
Keyword(s):  
Oral Premedication ◽  
Separation From Parents

scholarly journals To Compare the Efficacy of Oral Midazolam and Triclofos Sodium as Oral Premedication in Children of Sawangi, Maharashtra, India

2021 ◽  
Vol 10 (35) ◽  
pp. 2975-2979
Author(s):  
Aruna Vijay Chandak ◽  
Deepjit Bhuyan ◽  
Krishnendu S. ◽  
Vijay Chandak
Keyword(s):  
Elective Surgery ◽  
Paediatric Population ◽  
Hypnotics And Sedatives ◽  
Key Words Anaesthesia ◽  
Oral Midazolam ◽  
Successful Separation ◽  
Oral Premedication ◽  
Separation From Parents ◽  
Induction Of Anaesthesia ◽  
Better Than

BACKGROUND The perioperative habits contemplate showing that kids are in more danger of encountering fierce sedative enlistment and unfriendly social sequelae. In paediatric sedation, decent premedication is fundamental to lessen tension and disturbance in youngsters. Parental partition and odd operating room environment as a rule bring about blustery acceptance while giving general sedation. Narcotic premedication is vital for making kids quiet and cooperative in a weird environment. Our study was done to compare the efficacy of midazolam 0.5 mg / kg and triclofos sodium 100 mg / kg as oral premedications in children undergoing elective surgery. METHODS In this prospective randomised comparative study, sixty children posted for elective surgery were enrolled. The patients were randomly divided into midazolam group (Group M) and triclofos sodium group (Group T) of thirty each. Group M received oral midazolam 0.5 mg / kg 30 min before induction, and Group T received oral triclofos sodium 100 mg / kg 60 min before induction. All children were evaluated for level of sedation after premedication, behaviour at the time of separation from parents and at the time of mask placement for induction of anaesthesia. RESULTS Oral midazolam showed satisfactory sedation in children after premedication when compared to oral triclofos (P = 0.003). Both the drugs had a successful separation from parents, and the children were very cooperative during induction. No adverse effects attributable to the premedicants were seen. CONCLUSIONS Oral midazolam is better than triclofos sodium as a sedative anxiolytic in the paediatric population. KEY WORDS Anaesthesia, Hypnotics and Sedatives, Midazolam, Paediatrics, Premedication, Triclofos sodium

scholarly journals Oral Midazolam as a Pre-Medication in Paediatric Patients

2017 ◽  
Vol 4 (1) ◽  
pp. 30 ◽  
Author(s):  
Jayashree Phaltankar ◽  
Milin Shah
Keyword(s):  
Blood Pressure ◽  
Pulse Rate ◽  
Pediatric Patients ◽  
Emotional State ◽  
Study Group ◽  
Group I ◽  
Oral Midazolam ◽  
Group Ii ◽  
Oral Premedication ◽  
Separation From Parents

Introduction: In some medical circumstances, pediatric patients may need premedication for transferring to the operating room. In these situations, using oral premedication is preferred. We assessed the efficacy and safety of oral midazolam to reduce the anxiety and improve behavior in children undergoing general anesthesia. Method: In a double-blind randomized clinical trial, 90 children aged between 1-8 years were assigned to one of three oral premedication groups by random selection. Each group contained 30 children. Group I received 0.5 mg/kg oral midazolam Group II received 0.75 mg/kg oral midazolam both in 25% dextrose to a total volume of 5 ml. Group III or control group received 5 ml of 25% dextrose. To study its acceptility, onset and level of sedation, changes in vitals like pulse rate, blood pressure and emotional state before and after sedation, and post-op side effects. Disscussion: After premedication, difference in pulse rate, systolic blood pressure and respiratory rate between the three groups was not statistically significant sedation at 30 minutes after premedication was better in study group II as compared to study group I Emotional state was concluded to be better in study Group II (0.75 mg/ kg) as compared to study group I (0.5 mg/kg) at the time of separation from parents. More post operative complications like nausea, vomiting, giddiness, headache with a dose of 0.75 mg/kg than with a dose of 0.5 mg/kg. Conclusion: So we conclude that oral midazolam in a dose of 0.5 mg/kg for premedication in pediatric patients at it provides good to excellent sedation at 30 minutes at the time of separation from parents, with better quality of separation, and stable emotional state at induction without significant hemodynamic changes with less postoperative

scholarly journals Ketamine with Midazolam and Ketamine alone as oral premedication in children: a randomized trial

2018 ◽  
Vol 4 (2) ◽  
pp. 66-73 ◽  
Author(s):  
Jaya Prakash Thakur ◽  
Resham Bahadur Rana ◽  
Abhay Pokharel
Keyword(s):  
Low Dose ◽  
Traumatic Experiences ◽  
Parental Separation ◽  
Good Separation ◽  
Operation Theatre ◽  
Dose Combination ◽  
Oral Premedication ◽  
Separation From Parents ◽  
Double Blinded ◽  
Acceptance Score

Background: Fear of operation, injections, physicians and peculiar operation theatre environment where children are separated from their parents prior to anesthesia invariably produce traumatic experiences in tender mind of young children. Midazolam and Ketamine are useful for oral premedication in children to allay anxiety, allow separation from parents and to ensure smooth induction.Methodology: It was a prospective, randomized, double-blinded and comparative study conducted in 80 children of ASA I and II aged 1-6years undergoing elective ophthalmological procedures under general anesthesia. Children were randomized and divided into two groups, K received 4mg/kg of Ketamine and MK received 0.2mg/kg of Midazolam+2mg/kg of Ketamine peroral. Sedation level, ease of parental separation and ease of mask acceptance were evaluated within 20-30 minutes on a 4-point scale. The time to achieve modified Aldrete score of ≥9 was also noted.Results: Two groups were identical regarding age, sex, weight and ASA status. In sedation score, 31(77.5%) children in group K and 35(87.5%) children in group MK were awake, calm and quite (score3)(p=0.50). In parental separation score, 34(85%) children in group MK and 25(62.5%) children in group K have good separation, awake and calm (score2) (p=0.04). In mask acceptance score, 34(85%) children in group MK and 17(42.5%) children in group K were calm, awake, cooperative, accepting Mask (score1)(p=0.001). Time of recovery in group K was 17.92}6.50min whereas in group MK was 17.80}4.059min(p=0.91).Conclusion: Ketamine 4mg/kg and combination of Midazolam 0.2mg/kg with Ketamine 2mg/kg are equally effective but low dose combination is safe and superior. Journal of Society of Anesthesiologists of NepalVol. 4, No. 2, 2017, Page: 66-73 

Jewish Women's Psychological Well-Being: The Role of Attachment, Separation, and Jewish Identity

2005 ◽  
Vol 29 (2) ◽  
pp. 197-206 ◽  
Author(s):  
Julie L. Goldberg ◽  
Karen M. O'Brien
Keyword(s):  
Jewish Identity ◽  
Psychological Functioning ◽  
Well Being ◽  
Therapeutic Interventions ◽  
Jewish Women ◽  
Late Adolescent ◽  
Psychological Well Being ◽  
Separation From Parents ◽  
Anxiety Depression

The purpose of this study was to examine the contributions of attachment, separation, and Jewish identity to psychological well-being in a sample of 115 late adolescent Jewish women. Results from multiple regression analyses demonstrated that attachment to parents, separation from parents, and Jewish identity collectively accounted for variance in psychological distress, as measured by anxiety, depression, self-esteem problems, and interpersonal problems. Thus, late adolescent Jewish women's psychological functioning may be fostered by therapeutic interventions addressing their relationships with parents and Jewish identity.

scholarly journals Maternal speech decreases pain scores and increases oxytocin levels in preterm infants during painful procedures

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Manuela Filippa ◽  
Maria Grazia Monaci ◽  
Carmen Spagnuolo ◽  
Paolo Serravalle ◽  
Roberta Daniele ◽  
...  
Keyword(s):  
Preterm Infants ◽  
Pain Perception ◽  
Random Order ◽  
Pain Modulation ◽  
Protective Mechanism ◽  
Long Term Effects ◽  
Clinical Procedures ◽  
At Risk Populations ◽  
Cortisol Levels ◽  
Separation From Parents

AbstractPreterm infants undergo early separation from parents and are exposed to frequent painful clinical procedures, with resultant short- and long-term effects on their neurodevelopment. We aimed to establish whether the mother’s voice could provide an effective and safe analgesia for preterm infants and whether endogenous oxytocin (OXT) could be linked to pain modulation. Twenty preterm infants were exposed to three conditions—mother’s live voice (speaking or singing) and standard care—in random order during a painful procedure. OXT levels (pg/mL) in saliva and plasma cortisol levels were quantified, and the Premature Infant Pain Profile (PIPP) was blindly coded by trained psychologists. During the mother’s live voice, PIPP scores significantly decreased, with a concomitant increase in OXT levels over baseline. The effect on pain perception was marginally significant for singing. No effects on cortisol levels were found. The mother’s live voice modulated preterm infants’ pain indicators. Endogenous OXT released during vocal contact is a promising protective mechanism during early painful interventions in at-risk populations.

Sign in / Sign up

Export Citation Format

Share Document