scholarly journals Double-Network Carboxymethyl Chitosan Grafting Polyacrylamide/Alginate Hydrogel Compositions Adapted to Achieve High Stretchable Properties

2015 ◽  
Vol 09 (03) ◽  
Author(s):  
Duan J Liua Y ◽  
Liua L Jianga J
Keyword(s):  
Carboxymethyl Chitosan ◽  
Alginate Hydrogel ◽  
Double Network

scholarly journals Reduced Graphene Oxide-Based Double Network Polymeric Hydrogels for Pressure and Temperature Sensing

Sensors ◽  
2018 ◽  
Vol 18 (9) ◽  
pp. 3162 ◽  
Author(s):  
Wei Liu ◽  
Xiaoyuan Zhang ◽  
Gang Wei ◽  
Zhiqiang Su
Keyword(s):  
Graphene Oxide ◽  
Reduced Graphene Oxide ◽  
Mechanical Deformation ◽  
Temperature Sensors ◽  
Carboxymethyl Chitosan ◽  
Temperature Sensitive ◽  
Facile Synthesis ◽  
Bending Properties ◽  
Double Network ◽  
Reduced Graphene

We demonstrate the fabrication of novel reduced graphene oxide (rGO)-based double network (DN) hydrogels through the polymerization of poly(N-isopropylacrylamide) (PNIPAm) and carboxymethyl chitosan (CMC). The facile synthesis of DN hydrogels includes the reduction of graphene oxide (GO) by CMC, and the subsequent polymerization of PNIPAm. The presence of rGO in the fabricated PNIPAm/CMC/rGO DN hydrogels enhances the compressibility and flexibility of hydrogels with respect to pure PNIPAm hydrogels, and they exhibit favorable thermoresponsivity, compressibility, and conductivity. The created hydrogels can be continuously cyclically compressed and have excellent bending properties. Furthermore, it was found that the hydrogels are pressure- and temperature-sensitive, and can be applied to the design of both pressure and temperature sensors to detect mechanical deformation and to measure temperature. Our preliminary results suggest that these rGO-based DN hydrogels exhibit a high potential for the fabrication of soft robotics and artificially intelligent skin-like devices.

scholarly journals Cadmium(II) Capture Using Amino Functionalized Hydrogel with Double Network Interpenetrating Structure: Adsorption Behavior Study

2021 ◽  
Author(s):  
Sihua Liu ◽  
Haifei Wang ◽  
Jue Hu ◽  
Yue Li ◽  
guiyin zhou
Keyword(s):  
Heavy Metal ◽  
Adsorption Capacity ◽  
Raw Materials ◽  
Three Dimensional ◽  
Maximum Adsorption Capacity ◽  
Hydroxyl Groups ◽  
Alginate Hydrogel ◽  
Toxic Heavy Metal ◽  
Double Network ◽  
Behavior Study

Abstract Heavy metal pollution caused by the indiscriminate disposal of toxic heavy metal wastewater has become one of the serious water environmental issues. In this study, a novel NH2-PAA/Alginate hydrogel with double network interpenetrating structure was constructed with alginate, acrylic acid, and other raw materials. Characterized by SEM, this hydrogel shows a three-dimensional porous structure, which would be useful in adsorption process for its high diffusion coefficient. The results of adsorption experimental show that the NH2-PAA/Alginate possessed the well adsorption capacity when pH above 3.5, the maximum adsorption capacity calculated by Langmuir was 176.5 mg/g, the adsorption equilibrium can be achieved within 150 min. In addition, the NH2-PAA/Alginate has good recycling ability and stability. The results of XPS analysis reveal that the Cd(II) exchanged with Ca(II) and then coordinated with amino and hydroxyl groups in NH2-PAA/Alginate. The NH2-PAA/Alginate hydrogel can deal with all kinds of heavy metal ions and is a potential material for heavy metal adsorption.

Effect of Crosslinking on the Network Parameters, Swelling and Mechanical Properties of PVA-Borax and Poly (AM-co-HEMA) Double Network (DN) Hydrogels

2019 ◽  
Vol 35 (3) ◽  
pp. 371-391
Author(s):  
AKANSHA DIXIT ◽  
◽  
DIBYENDU S. BAG ◽  
DHIRENDRA KUMAR SHARMA ◽  
HARJEET SINGH ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Double Network ◽  
Network Parameters

Carboxymethyl-hexanoyl Chitosan Nanodroplets for Ultrasonic Imaging and Drug Delivery to Tumor

2018 ◽  
Vol 24 (15) ◽  
pp. 1682-1688 ◽  
Author(s):  
Yu Jinsui ◽  
Situ Bing ◽  
Luo Muhua ◽  
Li Yue ◽  
Liao Jianyi ◽  
...  
Keyword(s):  
Ultrasound Imaging ◽  
Tumor Therapy ◽  
Carboxymethyl Chitosan ◽  
Great Promise ◽  
Ovarian Cancer Cells ◽  
Mechanical Index ◽  
Surface Charges ◽  
Particle Structure ◽  
Drug Release Profile ◽  
Hexanoyl Chitosan

Introduction: Although a great many strategies have been proposed for tumor-targeted chemotherapy, current delivery methods of anticancer drugs present limited success with inevitable systemic toxicity. The aim of this study was to develop a new kind of theranostic carrier for targeted tumor therapy. Methods: Prior to prepare CHC-PFP-DOX, carboxymethyl-hexanoyl chitosan (CHC) was synthesized by acylation of carboxymethyl chitosan. To develop CHC-PFP, perfluoropentane (PFP), an ultrasound gas precursor, was simultaneously encapsulated into the hydrophobic inner cores of pre-formulated CHC micelle in aqueous phase via using the oil in water (O/W) emulsion method. The size distribution and surface charges of these nanodroplets were measured and the morphology was observed by transmission electron microscopy (TEM). For ultrasound imaging application, in vitro model was established to evaluate the imaging of CHC-PFP-DOX under different concentration and mechanical index. After that, the anti-tumor effect of ultrasound combined with CHC-PFPDOX on ovarian cancer cells was investigated. Results: The resulting CHC-PFP-DOX had a nano-sized particle structure, with hydrophobic anticancer DOX/PFP inner cores and a hydrophilic carboxymethyl chitosan polymer outer shell. The favorable nano-scaled size offers the potential to extravagate from veins and accumulate in tumor tissues via enhanced permeation and retention (EPR) effect. Additionally, CHC-PFP-DOX showed the ability to serve as ultrasound imaging agent at body temperature. Notably, it exhibited an ultrasound-triggered drug release profile through the external ultrasound irradiation. Further study demonstrated that ultrasound combined with CHC-PFP-DOX can improve the killing effect of chemotherapy for tumor. Conclusion: CHC-PFP-DOX holds great promise in simultaneous cancer-targeting ultrasound imaging and ultrasound- mediated delivery for cancer chemotherapy.

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