An investigation of the barriers and facilitators of adherence in relation to amendable risk factors in the primary prevention of cleft lip and palate

2018 ◽  
Vol 04 ◽  
Author(s):  
Dalia Bajabir ◽  
Peter Mossey ◽  
Nicola Innes ◽  
Steve MacGillivray
Keyword(s):  
Risk Factors ◽  
Primary Prevention ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Barriers And Facilitators

A Prospective, Longitudinal Study of Feeding Skills in a Cohort of Babies with Cleft Conditions

2006 ◽  
Vol 43 (6) ◽  
pp. 702-709 ◽  
Author(s):  
Julie Reid ◽  
Nicky Kilpatrick ◽  
Sheena Reilly
Keyword(s):  
Risk Factors ◽  
Cleft Palate ◽  
Motor Function ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Oral Motor ◽  
Feeding Efficiency ◽  
Oral Motor Function ◽  
Feeding Skills ◽  
Prospective Longitudinal

Objective: To examine the natural history of feeding skills in babies with clefts and identify risk factors and predictors of poor feeding. Participants: Sixty-two babies with clefts were examined at 2 weeks, 3 months, and 14 months of age. Main Outcome Measures: Feeding ability, oral motor function, and feeding efficiency were assessed. Univariate analyses were used to determine whether oral motor function and sequelae varied according to feeding ability or cleft condition. Multivariable logistic regressions were used to determine risk factors for poor feeding. Results: Poor feeding skills were detected in one third of newborns. The prevalence of poor feeding reduced to 19% at 3 months of age and 15% at 14 months of age. Oral motor dysfunction and sequelae (particularly nasal regurgitation) were more commonly observed in babies with poor feeding skills irrespective of comorbidity. The main risk factor for poor feeding was a diagnosis of syndrome or Pierre Robin sequence (PRS). At 2 weeks of age, babies with syndrome or PRS were 15 times more likely to have poor feeding skills than their nonsyndromic counterparts. When syndrome or PRS was controlled for, babies with cleft palate and cleft lip and palate were equally likely to have poor feeding skills. Parental report of feeding efficiency was predictive of poor feeding in young babies. Conclusions: Poor feeding skills are relatively common in newborns with cleft palate and cleft lip and palate. Treatment for feeding problems may be needed beyond the first year of life, especially for babies born with PRS or a syndrome.

scholarly journals Environmental risk factors for cleft lip and palate in low-resource settings: a case-control study

2019 ◽  
Vol 7 ◽  
pp. S19
Author(s):  
Allyn Auslander ◽  
Roberta Mckean-Cowdin ◽  
Frederick Brindopke ◽  
Kathy Magee ◽  
Melissa DiBona ◽  
...  
Keyword(s):  
Risk Factors ◽  
Environmental Risk ◽  
Cleft Lip ◽  
Case Control Study ◽  
Cleft Lip And Palate ◽  
Case Control ◽  
Environmental Risk Factors ◽  
Low Resource Settings ◽  
Low Resource ◽  
Control Study

scholarly journals FREQUENCY AND RISK FACTORS AFFECTING THE BIRTH RATE OF CHILDREN WITH CONGENITAL CLEFT LIP AND PALATE IN THE SOUTHERN REGION OF KYRGYZSTAN.

ASJ. ◽  
2021 ◽  
Vol 1 (50) ◽  
pp. 10-13
Author(s):  
A. Eshiev ◽  
N. Taalaibekov ◽  
E. Derbishev
Keyword(s):  
Risk Factors ◽  
Infectious Diseases ◽  
Hard Palate ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Maxillofacial Surgery ◽  
First Trimester ◽  
Southern Region ◽  
Comprehensive Treatment ◽  
Congenital Cleft

The aim of the study is to examine the incidence and factors of congenital cleft lip and palate in the southern region of the Kyrgyz Republic, according to the form of clefts and according to the classification of MMDI, as well as their rehabilitation. We studied in detail the case histories of 2116 patients treated in the maxillofacial surgery department of Osh Interregional United Clinical Hospital according to the age and sex, as well as the form of congenital cleft lip and palate. Moreover, a questionnaire was administered to parents of children with CCLP for risk factors during pregnancy. A retrospective study of medical history revealed, among congenital anomalies, clefts of the soft, hard palate, alveolar process and upper lip prevailed - (combined) 891 (42,3%) Congenital cleft of soft, hard palate - 586 (27,7%), then isolated congenital cleft of the maxilla - 415 (19,6%), congenital cleft of the soft palate only 10,5% - 224 children were followed. The results of the questionnaire revealed that the parents of children born with CCLP were influenced by various unfavorable factors in the period of formation of the facial section of the fetus. The survey revealed that the relatives had CCLP, which accounted for 12.9% of all newborns, indicating a rather high role of hereditary predisposition. In addition to the hereditary genetic factor, an important role is played by infectious diseases suffered during the first trimester. It is noted that 12.8% of the children born with CCLP had infectious diseases. The mothers independently took drugs during pregnancy (antibiotics, salicylates, sulfonamides without a doctor's prescription), 17.6% of women were anemic during pregnancy, and 16.3% had severe toxemia. Along with this, it was found that the smallest number of women suffered mental trauma in the first trimester of pregnancy 0.4% of the mothers of children born with CCLP. Further, we registered patients with CCLP in the special software ONYX CEPH-3 from 01.01.2015 to the present, where we enter detailed information about patients with CCLP pathology. It creates convenience for parents both informationally and economically, as well as directly for the doctor in terms of dynamic observation of the functional and aesthetic condition and development of the child. In order to further develop programs to prevent the prevalence of congenital pathology, improve the quality of comprehensive treatment method, as well as medical and social rehabilitation of such patients and work with families of children with CCLP, we have developed a single program ONYX CEPH3 providing dispensary and rehabilitation of children.

scholarly journals Prevalence of cleft lip and palate in cousin marriages

2016 ◽  
Vol 12 (1) ◽  
Author(s):  
Humera Zafar ◽  
Farid Ahmad Khan ◽  
Muhammad Umar Farooq ◽  
Noor Ahmad Niazi ◽  
Zafar F ◽  
...  
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Birth Defects ◽  
Retrospective Review ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Developed Countries ◽  
Cleft Lip Palate

Background: Birth defects are one of the leading causes of paediatric disability and mortality in developing as well as developed countries. The purpose of this study is to report our 3 months experience regarding the prevalence of cleft lip and palate in cousin marriages. Methods: A retrospective review of 50 patients who presented with cleft lip or cleft lip/palate during 3 months, from 9th March to 8th June, 2005 was carried out.. Results: Among the risk factors cousin marriages is a most frequent risk factor. Cleft lip is more common than cleft lip/palate and cleft lip alone is a different entity than cleft lip and palate combined.

scholarly journals Fatores de Riscos na Fissura Labiopalatina Não Sindrômica

UNICIÊNCIAS ◽  
2021 ◽  
Vol 24 (1) ◽  
pp. 86-93
Author(s):  
Carla Meliso Rodrigues Silvestre ◽  
Renata Cristina Giroto Ferreira da Silva ◽  
Ageo Mario Candido da Silva ◽  
Walkiria Shimoya Bittencourt ◽  
Yolanda Benedita Abadia Martins de Barros ◽  
...  
Keyword(s):  
Risk Factors ◽  
Environmental Factors ◽  
Literature Review ◽  
Cleft Palate ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
First Trimester ◽  
Human Beings ◽  
Factors Associated ◽  
Narrative Literature Review

As anomalias craniofaciais representam um grupo amplo de malformações congênitas que afetam uma grande proporção da sociedade mundial. Entre essas se encontram as fissuras de lábio e/ou de palato, anomalia orofacial mais frequente entre os seres humanos que ocasionam problemas estéticos e funcionais nos indivíduos afetados.  A etiologia das fissuras labiopalatinas isoladas ou não-sindrômicas é complexa e multifatorial, associadas à fatores hereditários e ambientais. Este estudo teve como objetivo relatar os fatores genéticos e ambientais associados à etiologia desse tipo de malformação, através de uma revisão narrativa de literatura, a partir das bases de dados: PubMed e Scielo. Os descritores utilizados foram: cleft palate AND cleft lip AND etiology AND risk factors. Incluíram-se artigos nos idiomas inglês e português publicados em periódicos nacionais e internacionais acerca da temática da pesquisa. Baseado na revisão de literatura se pode identificar que os fatores ambientais como: fumo, consumo de álcool, consumo de medicamentos, o não uso de suplementação com polivitamínicos e ácido fólico, exposição a agrotóxicos, idade dos genitores podem aumentar a chance de ocorrência das fissuras labiopalatinas. O acompanhamento gestacional durante o primeiro trimestre gestacional se faz necessário, a fim de monitorar os fatores de risco associados com as fissuras labiopalatinas não sindrômicas.   Palavras-chave: Fissura Palatina. Fenda Labial. Etiologia. Fatores de Risco.   Abstract Craniofacial anomalies represent a broad group of congenital malformations that affect a large proportion of world society. Among them are cleft lip and / or palate, the most frequent orofacial anomaly among human beings that cause aesthetic and functional problems in the affected individuals. The etiology of isolated or non-syndromic cleft lip and palate is complex and multifactorial, associated with hereditary and environmental factors. This study aimed to report the genetic and environmental factors associated with the etiology of this type of malformation through a narrative literature review conducted in October 2020, using the PubMed and Scielo databases. The keywords used were cleft palate AND cleft lip AND etiology AND risk factors. Articles in English and Portuguese published in national and international journals about the research theme were included. Based on the literature review, it can be identified that environmental factors such as smoking, alcohol consumption, medication consumption, the non-use of supplementation with multivitamins and folic acid, exposure to pesticides, age of parents can increase the chance of cleft lip and palate occurrence. Gestational monitoring during the first trimester of pregnancy is necessary in order to monitor the risk factors associated with non-syndromic cleft lip and palate.   Keywords: Cleft Palate. Cleft Lip. Etiology. Risk Factors.

National Estimates of and Risk Factors for Inpatient Revision Surgeries for Orofacial Clefts

2017 ◽  
Vol 54 (1) ◽  
pp. 60-69 ◽  
Author(s):  
Jeffrey A. Thompson ◽  
Pamela C. Heaton ◽  
Christina M.L. Kelton ◽  
Thomas J. Sitzman
Keyword(s):  
Risk Factors ◽  
Cleft Palate ◽  
Revision Surgery ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Care Delivery ◽  
Private Insurance ◽  
Hospitalization Costs ◽  
National Estimates ◽  
The Impact

Objective To provide national estimates of the number and cost of primary and revision cleft lip and palate surgeries in the U.S. and to determine patient and hospital characteristics associated with disproportionate use of revision surgery. Design Retrospective cross-sectional study using data obtained from the 2003, 2006, and 2009 Kids’ Inpatient Database. Setting Inpatient. Patients Children with CL, CP, or CLP undergoing inpatient cleft lip and/or palate surgery. Interventions Inpatient cleft lip and/or palate surgery. Main Outcome Measures Orofacial cleft surgery estimates, estimates of primary versus revision surgeries, and estimated inflation-adjusted hospitalization costs. Results In 2009, there were a total of 2824 and 5431 hospitalizations for cleft lip and palate surgeries, respectively. Revision surgery accounted for 24.2% of cleft lip surgeries and 36.8% of cleft palate surgeries. Children with CLP (OR 1.87, 95% CI 1.48-2.38), a syndromic diagnosis (OR 1.47, 95% CI: 1.16-1.87), or private insurance (OR 1.71, 95% CI: 1.41-2.09) were more likely to undergo cleft lip revision surgery. Similar risk factors were found for children undergoing cleft palate revision. Mean cost per hospitalization ranged from $7564 to $8393 in 2009, depending on surgery type, and did not change significantly (in 2009 U.S. $) between 2003 and 2009. Conclusions Interventions to reduce revision surgery by improving results of primary surgery should be targeted in the population of identified high-risk (e.g., syndromic) patients. In addition, the association of health insurance status with revision surgery highlights the need to understand and address the impact of economic disparities on cleft care delivery.

Efficacy of Maxillary Anterior Segmental Distraction Osteogenesis in Patients With Cleft Lip and Palate

2018 ◽  
Vol 55 (10) ◽  
pp. 1375-1381 ◽  
Author(s):  
Chihiro Tanikawa ◽  
Kae Hirata ◽  
Tomonao Aikawa ◽  
Jun Maeda ◽  
Mikihiko Kogo ◽  
...  
Keyword(s):  
Risk Factors ◽  
Distraction Osteogenesis ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Japanese Patients ◽  
Median Percentage ◽  
Counterclockwise Rotation ◽  
Anterior Nasal Spine ◽  
Lateral Cephalograms ◽  
Study Inclusion

Objectives: To evaluate the effects of maxillary anterior segmental distraction osteogenesis (MASDO) in patients with cleft lip and palate (CLP) and to identify risk factors for increased relapse. Design: A retrospective study. Patients: Thirty-one Japanese patients with CLP who underwent MASDO were eligible for study inclusion. Main Outcome Measures: We evaluated lateral cephalograms obtained before (T1), at 3 months (T2), and at 1 year (T3) after MASDO, and measured changes from T1 to T2 (δT1T2), from T2 to T3 (δT2T3), and from T1 to T3 (δT1T3). We also evaluated the risk factors associated with an increased relapse. Results: Overall (δT1T3), MASDO improved retrusion of the maxilla. We measured a significant advancement (6.1 mm) of the anterior maxillary segment in δT1T2 (A-McNamara classification) and increases in the overjet and the SNA, ANB, and nasolabial angles. However, skeletal relapse was evident in δT2T3, and the median percentage of relapse was 10%. To explore the risk factors, we subdivided patients with a δT1T2 of >5 mm into 2 groups based on the percentage of relapse (>15% vs ≤15%). There were significant differences between these groups in the vertical positions of the anterior nasal spine and point A, and the angle formed by the SN and palatal planes (SNPP), suggestive of intraoperative counterclockwise rotation of the maxilla. Conclusions: MASDO is effective for correcting midfacial deficiencies, but counterclockwise rotation of the maxilla during surgery may cause relapse.

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