scholarly journals The Use of Proton Pump Inhibitors and Prescription Pattern by Practicing Physicians at an Academic Hospital

2017 ◽  
Vol 24 (4) ◽  
pp. 9-14
Author(s):  
Mohammed A. Basheikh
Keyword(s):  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Cross Sectional Study ◽  
University Hospital ◽  
Gastrointestinal Disorders ◽  
Academic Hospital ◽  
Cross Sectional ◽  
King Abdulaziz University ◽  
Different Levels ◽  
Practicing Physicians

The introduction of proton pump inhibitors has revolutionized the management of acid-related gastrointestinal disorders. Physicians use different regimen when prescribing proton pump inhibitors. In this study we aim to determine the prevalence and pattern of proton pump inhibitors prescription among practicing physicians at King Abdulaziz University Hospital in Jeddah, Saudi Arabia. A cross-sectional study was performed at different levels of doctors ranging from consultants to house officers from March-May 2014. The study included 85 doctors. The prevalence of proton pump inhibitors prescription was 57.65%. Most of the respondents are internal medicine physicians with 58.62% (29 physicians) of them prescribing proton pump inhibitors. As well, half of the surgeons (24) were prescribing proton pump inhibitors. 54.17% of house officers who participated were prescribing proton pump inhibitors. Omeprazole at a dose of 20 mg is the most commonly prescribed by 49.41%, followed by the dose 40 mg prescribed by 41.18%. The rate of prescription for proton pump inhibitors at King Abdulaziz University Hospital with different specialties and levels is comparable to the practice worldwide. It’s noted that house officers are prescribing proton pump inhibitors; they will need to be educated about the use, dosage, and side effects of proton pump inhibitors.

Prevalence and Associations of the Use of Proton-Pump Inhibitors in Nursing Homes: A Cross-Sectional Study

2013 ◽  
Vol 14 (4) ◽  
pp. 265-269 ◽  
Author(s):  
Philipe de Souto Barreto ◽  
Maryse Lapeyre-Mestre ◽  
Céline Mathieu ◽  
Christine Piau ◽  
Catherine Bouget ◽  
...  
Keyword(s):  
Nursing Homes ◽  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals Vitamin D Status in Postmenopausal Females in Saudi Arabia

2020 ◽  
Vol 79 (OCE2) ◽  
Author(s):  
Shatha Alharazy ◽  
Eman Alissa ◽  
Adeel Chaudhary ◽  
Susan Lanham-New ◽  
M. Denise Robertson
Keyword(s):  
Vitamin D ◽  
Saudi Arabia ◽  
Postmenopausal Women ◽  
Cross Sectional Study ◽  
University Hospital ◽  
Older Individuals ◽  
Anthropometric Measures ◽  
Cross Sectional ◽  
Jeddah City ◽  
King Abdulaziz University

AbstractVitamin D (vitD) deficiency is highly prevalent in the Middle East (including Saudi Arabia) despite the abundance of sunlight. Older individuals in particular are at high risk of being vitD deficient. VitD binding protein (DBP), which acts as a carrier of vitD and its metabolites, has been reported to influence vitD status. In our study we aimed to investigate vitD status among postmenopausal women and its relation to DBP. A cross-sectional study was conducted at the King Fahad Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia. Seventy six postmenopausal females (age ≥ 50 years) who were not taking vitD supplementation and who were resident in Jeddah city, were randomly recruited from internal medicine clinics at King Abdulaziz University Hospital. Anthropometric measures, blood pressure, lifestyle history, dietary vitD intake and fasting blood samples were obtained from all study participants. Serum total 25 hydroxy-vitamin D (25(OH)D), DBP, albumin, parathyroid hormone, calcium, phosphate, magnesium and metabolic bone parameters were analysed. VitD deficiency was defined as serum total 25(OH)D level below 30 nmol/L. The mean (± SD) serum level of total 25(OH)D was 46.9 ± 28.9 nmol/L with 36 % of the study population being vitD deficient. Although non-significant, the vitD deficient group had lower DBP and higher dietary vitD intake levels when compared with those with serum vitD > 30nmol/L. In addition, DBP was inversely correlated with vitD dietary intake (r = -0.233, P = 0.046). In conclusion, vitD deficiency is highly prevalent among postmenopausal women living in Jeddah, Saudi Arabia. Intake of a vitD rich food seems to be associated with low DBP levels. Genetic polymorphisms in DBP will be studied in the future to find out a possible explanation for the differences in vitD status and DBP between individuals as well as the concomitant relationship between dietary vitD intake, DBP and serum 25(OH)D levels.

scholarly journals The Burden of Potentially Inappropriate Medications in Chronic Polypharmacy

2020 ◽  
Vol 9 (11) ◽  
pp. 3728
Author(s):  
Jordan Guillot ◽  
Sandy Maumus-Robert ◽  
Alexandre Marceron ◽  
Pernelle Noize ◽  
Antoine Pariente ◽  
...  
Keyword(s):  
Older Adults ◽  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Cross Sectional Study ◽  
Potentially Inappropriate Medications ◽  
Middle Aged ◽  
Cross Sectional ◽  
Long Acting ◽  
Chronic Use ◽  
Inappropriate Medications

We aimed to describe the burden represented by potentially inappropriate medications (PIMs) in chronic polypharmacy in France. We conducted a nationwide cross-sectional study using data from the French National Insurance databases. The study period was from 1 January 2016 to 31 December 2016. Chronic drug use was defined as uninterrupted daily use lasting ≥6 months. Chronic polypharmacy was defined as the chronic use of ≥5 medications, and chronic hyperpolypharmacy as the chronic use of ≥10 medications. For individuals aged ≥65 (older adults), PIMs were defined according to the Beers and Laroche lists, and for individuals aged 45–64 years (middle-aged) PIMs were defined according to the PROMPT (Prescribing Optimally in Middle-aged People’s Treatments) list. Among individuals with chronic polypharmacy, 4009 (46.2%) middle-aged and 18,036 (64.8%) older adults had at least one chronic PIM. Among individuals with chronic hyperpolypharmacy, these figures were, respectively, 570 (75.0%) and 2544 (88.7%). The most frequent chronic PIM were proton pump inhibitors (43.4% of older adults with chronic polypharmacy), short-acting benzodiazepines (older adults: 13.7%; middle-aged: 16.1%), hypnotics (6.1%; 7.4%), and long-acting sulfonylureas (3.9%; 12.3%). The burden of chronic PIM appeared to be very high in our study, concerning almost half of middle-aged adults and two-thirds of older adults with chronic polypharmacy. Deprescribing interventions in polypharmacy should primarily target proton pump inhibitors and hypnotics.

scholarly journals Parental Knowledge, Attitudes, and Behaviors Toward Their Epileptic Children at King Abdulaziz University Hospital: Cross-Sectional Study (Preprint)

2018 ◽  
Author(s):  
Abdulelah Kinkar ◽  
Dalya Alqarni ◽  
Abdulaziz Alghamdi ◽  
Sahal Wali ◽  
Nasser Alghamdi ◽  
...  
Keyword(s):  
Educational Level ◽  
Parental Knowledge ◽  
Cross Sectional Study ◽  
University Hospital ◽  
Sectional Study ◽  
Significant Relation ◽  
Cross Sectional ◽  
Epileptic Children ◽  
King Abdulaziz University ◽  
The Mean

BACKGROUND Epilepsy is a chronic disease characterized by periodic seizures that result from abnormal integrated firing impulses in the brain. It is one of the most common neurological disorders. Over the past few years, there has been increasing awareness about the effect that having a child with epilepsy has on parents and the reciprocal impact of parental knowledge and attitudes regarding epilepsy on the affected child. OBJECTIVE This study aimed to assess parental knowledge, attitudes, and behavior toward their epileptic children. METHODS A cross-sectional study was conducted in 2018 by the Pediatric Neurology Department of King Abdulaziz University Hospital, Jeddah, the Kingdom of Saudi Arabia. A sample size of 115 of 332 parents who have a child diagnosed with epilepsy and aged 18 years or younger were recruited for this study. Statistical analysis was performed using SPSS version 21. Data analysis was performed using an independent <italic>t</italic> test, a chi-square test, one-way analysis of variance, and correlation analysis. RESULTS A total of 115 participants answered the questionnaire; of these, 65 (56.5%) were men, with an average age of 40.3 years, and the mean age of the children was 9.0 years. Overall, 85 (85/115, 73.9%) children were taken care of by both of their parents. The mean parental knowledge score was 7.49 (SD 2.08) out of 12, and it was significantly related to the educational level of the parent (<italic>P</italic>=.004). The knowledge question that was most frequently answered incorrectly was “Diagnosis of epilepsy is usually made based on at least two unprovoked seizures.” As only 28.7% (33/115) of participants chose the correct answer, mean parental attitude score was 26.51 (SD 4.284) out of 35, and there was no significant relation with the educational level of parents (<italic>P</italic>=.13); however, it was negatively correlated with the child’s age (<italic>P</italic>=.045). Mean parental behavioral score was 23.35 (SD 4.121) out of 35, and there was no significant relation with the educational level of the parents (<italic>P</italic>=.24). The most negatively answered question for the behavior section was “I can leave my child without supervision,” with a mean score of 2.25 (SD 1.09) out of 5. Gender did not play a significant role in parental knowledge, attitudes, or behavior (<italic>P</italic>=.44, <italic>P</italic>=.77, and <italic>P</italic>=.99, respectively). CONCLUSIONS Parental knowledge in our sample still needs improvement. Therefore, more awareness campaigns should be made for the community and for the parents of affected children to create a supportive environment for the children and help them thrive and develop.

scholarly journals Awareness and Level of Knowledge About Surgical Site Infections and Risks of Wound Infection Among Medical Physicians in King Abdulaziz University Hospital: Cross-Sectional Study (Preprint)

2018 ◽  
Author(s):  
Wahbi Albishi ◽  
Marwan Ahmad Albeshri ◽  
Hatan Hisham Mortada ◽  
Khaled Alzahrani ◽  
Rakan Alharbi ◽  
...  
Keyword(s):  
Wound Infection ◽  
Wound Care ◽  
Quality Care ◽  
Surgical Site Infections ◽  
Cross Sectional Study ◽  
University Hospital ◽  
Cross Sectional ◽  
King Abdulaziz University ◽  
Level Of Knowledge ◽  
Definition Of

BACKGROUND Surgical site infections (SSIs) are one of the leading causes of death, and its prevention is a key element of applying the concept of patient safety and quality care. OBJECTIVE This study aimed to assess the level of knowledge about SSIs and risks of wound infection among medical physicians in King Abdulaziz University Hospital. METHODS All surgical and medical consultants, specialists, residents, and medical interns were invited to participate in the study. A 20-Item multiple-choice questionnaire was developed by reviewing the previous literature and with the help of a group of certified surgeons to assess the level of knowledge in all participants. RESULTS A total of 119 doctors were included in this study. Among all respondents, 92 (77.3%) were intern doctors, 16 (13.4%) were resident doctors, and 11 (9.2%) were specialist doctors. Moreover, 66 (55.5%) doctors knew the definition of SSI. Only one-quarter, that is, 30 (25.2%) doctors knew about the incidence of SSI. In addition, 8 doctors (6.7%) had good knowledge, 75 (63.0%) had fair knowledge, and 36 (30.2%) had poor knowledge regarding SSI according to this study. CONCLUSIONS Level of knowledge about SSIs and risks of wound infections among medical physicians should be improved to ensure better wound care and quality care for the patients.

scholarly journals Prevalence of APOL1 Risk Variants in Afro-Descendant Patients with Chronic Kidney Disease in a Latin American Country

2019 ◽  
Vol 2019 ◽  
pp. 1-5
Author(s):  
Carlos E. Duran ◽  
Alejandro Ramírez ◽  
Juan G. Posada ◽  
Johanna Schweineberg ◽  
Liliana Mesa ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Electronic Medical Records ◽  
Latin American ◽  
Medical Records ◽  
Cross Sectional Study ◽  
University Hospital ◽  
Cross Sectional ◽  
Risk Variants ◽  
Different Levels

Introduction. In Colombia, the genetic background of the populations was shaped by different levels of admixture between Natives, European, and Africans. Approximately 35.363 patients have diagnosed chronic kidney disease and according to population studies, 10.4% of these patients are Afro-descendant. We aim to assess the frequency of APOL1 variants G1 and G2 in Afro-descendant patients with ESRD treated at la Fundacion Valle del Lili University Hospital in Cali, Colombia. Methods. This is an observational cross-sectional study. Afro-descendant patients with ESRD in waitlist or recipients of kidney transplant were evaluated. Clinical data were collected from the electronic medical records. Genotyping was carried out by amplification of the exon 7 of the APOL1 gene. For the identification of risk genotypes, the bioinformatics tool BLAST was used. Results. We enrolled 102 participants. The frequency of APOL1 risk variants was 67.2%, in which 24.5% (n = 25) were G1 heterozygous and 5.8% (n = 6) were G2 heterozygous and 37% of the patients had high-risk status with two alleles in homozygous (G1/G1 = 21 and G2/G2 = 3) or compound heterozygote (G1/G2 = 14) form.

A Cross-Sectional Study on Single-Day Use of Proton Pump Inhibitors in Tertiary Care Hospitals of South India

2019 ◽  
pp. 001857871987387
Author(s):  
Zabiuddin Ahad M ◽  
Alekhya Lavu ◽  
Maria Ansari ◽  
Raviraj Acharya V ◽  
Rajesh Vilakkathala
Keyword(s):  
Drug Interactions ◽  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
South India ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Teaching Hospitals ◽  
Intravenous Route ◽  
Sectional Study ◽  
Cross Sectional

Background: Proton pump inhibitors (PPIs) are the most potent antacids used in clinical practice with greater safety and efficacy. Limited data are available on the usage of PPIs in Indian health-care settings. Our aim was to understand the usage pattern and potential drug interactions with concurrently administered medications employing a single-day cross-sectional study design. Methods: A prospective observational cross-sectional study conducted on a single day, at two tertiary care teaching hospitals in South India. Inpatients of above 18 years of age were included. Case profiles were reviewed and data were collected in predesigned forms and analyzed. Drug interactions were identified using Micromedex and Medscape drug-interaction databases. Results: A total of 797 case profiles screened from both the centers; 714 were prescribed with PPIs. In intensive care units (ICUs), the use of PPIs was highest with 95% of cases getting these drugs. A PPI was seen in about 93% of patients, who had more than or equal to 4 drugs in their prescriptions. Pantoprazole was the mostly prescribed PPI in around 90% of the cases. Around 33% of the PPIs usage was through IV (intravenous) route, and 75% of that use was seen in wards. Around 134 drug interactions were identified, of which 10 were of major severity. Conclusions: Around 90% of inpatients were prescribed with PPIs. Pantoprazole is the most commonly prescribed PPI (90%). The IV administration was seen more in wards than ICUs, and 10 major drug interactions were observed in this single-day study. Careful monitoring is needed to avoid serious drug interactions involving PPIs, and training programs should sensitize the clinicians on the evidence-based use of PPIs.

Hypomagnesemia in hemodialysis patients taking proton pump inhibitors

2020 ◽  
Vol 14 (2) ◽  
pp. 55-58
Author(s):  
Abdul Malik ◽  
Syed Mohkumuddin ◽  
Humaira Rahim ◽  
Shamima Hanif
Keyword(s):  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Serum Magnesium ◽  
Cross Sectional Study ◽  
Hemodialysis Patients ◽  
Mean Value ◽  
Female Dominance ◽  
P Value ◽  
Cross Sectional ◽  
The Mean

Background: Proton pump inhibitors (PPIs) are in routine widely prescribed to hemodialysis patients. Recent studies have reported the association of PPIs use with hypomagnesemia in patients with long term hemodialysis. This study aims to determine the frequency of hypomagnesemia in patients of hemodialysis taking proton pump inhibitors. Patients and methods: This cross-sectional study was conducted in the Department of Nephrology of Sandman Provincial Hospital Quetta from 01-6-2019 till 01-9-2019. A total of 120 patients (52 PPI users and 68 non-PPI users) who were on HD for more than 06 months were included. Data regarding age, gender, duration of hemodialysis and taking PPIs were collected. Determination of serum magnesium was made by taking 3 different samples at 2 weeks’ interval and the mean value of serum magnesium was calculated. Serum Mg2+ levels <2.0 mg/dL was taken as hypomagnesemia. A Chi-square test was applied to determine the association of PPI use with hypomagnesemia. Results: Demographic variables such as age and gender were not significantly different between the groups. There was female dominance in both groups (73% in PPI groups and 66.1% in the non-PPI group (p-value 0.65). The mean duration of dialysis was 45.3±13.8 months in PPI users versus 48.9±12.9 months in non-PPI users (p-value 0.14). There was a significantly higher frequency of hypomagnesemia in PPI users; 36 (69.3%) versus 27 (39.7%) in non-PPI users (p-value 0.001). Conclusion: The use of PPI is associated with a significant reduction in serum magnesium levels. So serum magnesium levels should be advised as routine monitoring in patients of hemodialysis taking PPIs.

Colostrum knowledge among Saudi mothers in Jeddah, Saudi Arabia

2020 ◽  
pp. 1-13
Author(s):  
Steve Harakeh ◽  
Musab Almatrafi ◽  
Rahma Bukhari ◽  
Turki Alamri ◽  
Salah Barnawi ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Occupational Status ◽  
Cross Sectional Study ◽  
University Hospital ◽  
Cross Sectional ◽  
Saudi Women ◽  
Lactating Mothers ◽  
High Knowledge ◽  
King Abdulaziz University ◽  
Community Data

Abstract Objective: To assess the knowledge level of Saudi women about colostrum for the newborns. Methods: The cross-sectional study was conducted from October 2015 to June 2016 at the Gynecological Clinics of King Abdulaziz University Hospital, Jeddah, Saudi Arabia, and comprised lactating mothers in the community. Data was collected using a pretested questionnaire. Data was analysed using SPSS 22. Results: of the 552 mothers, 301(54.5%) were age >30 years. The source of information about colostrum was friends and family for 367(66.67%) subjects. Overall, 367(66%) had high knowledge about colostrum. A significant correlation was detected between age and knowledge about colostrum composition and duration (p<0.05); as well as between educational level and colostrum composition, colour, and form (p<0.05). A significant association between occupational status and knowledge about colostrum colour and form was also noted (p<0.05). Conclusion: Saudi mothers were found to have a good knowledge about colostrum and its benefits. Key Words: Colostrum knowledege, Breastfeeding, Pregnancy, NewbornI, Immunity. Continuous...

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