Vehicle Handling and Stability Investigation into Causes of Vehicle Drift during Straight-Line Braking

Author(s):  
Nihal Mirza ◽  
Khalid Hussain ◽  
Andrew J. Day
Author(s):  
K. V. L. D. SPANDANA ◽  
N. J. P. SUBHASHINI

Objective: The focus of our research was to create a fairly sensitive HPLC stratagem for determining telmisartan (TLM) and azelnidipine (AEL) in bulk and tablet types. Methods: Analysis of TLM and AEL was performed on a “C18 Kromasil stationary column (5 µm, 250 mm × 4.6 mm)”. The mobile phase was made of 0.1M NaH2PO4 solution (pH 3.5) and methanol at a comparative volume ratio of 50% each. The analysis of TLM and AEL was isocratic, with the flow velocity adjusted at 1.0 ml/min and indeed, the TLM and AEL analysis was done at 256 nm using a PDA device sensor. TLM and AEL were stressed with acid, peroxide, dry heat, alkali, and sunlight-induced settings. Results: The retention/elution periods for the TLM and AEL were observed at 2.225 min and 3.178 min, respectively. The HPLC stratagem developed have a straight-line relation with relative concentrations in the ranges of 20-60 µg/ml for TLM and 4-12 µg/ml for AEL. The LOQ’s for TLM and AEL were 0.2516 μg/ml and 0.0871 μg/ml, respectively. The validation investigational findings done for TLM and AEL with the established sensitive HPLC stratagem were passed out in conformity with the ICH standards. Conclusion: The established sensitive HPLC stratagem was shown as competent for the quality check of bulk samples of TLM and AEL throughout batch release as well as in the course of TLM and AEL stability investigations.


Author(s):  
D.R. Ensor ◽  
C.G. Jensen ◽  
J.A. Fillery ◽  
R.J.K. Baker

Because periodicity is a major indicator of structural organisation numerous methods have been devised to demonstrate periodicity masked by background “noise” in the electron microscope image (e.g. photographic image reinforcement, Markham et al, 1964; optical diffraction techniques, Horne, 1977; McIntosh,1974). Computer correlation analysis of a densitometer tracing provides another means of minimising "noise". The correlation process uncovers periodic information by cancelling random elements. The technique is easily executed, the results are readily interpreted and the computer removes tedium, lends accuracy and assists in impartiality.A scanning densitometer was adapted to allow computer control of the scan and to give direct computer storage of the data. A photographic transparency of the image to be scanned is mounted on a stage coupled directly to an accurate screw thread driven by a stepping motor. The stage is moved so that the fixed beam of the densitometer (which is directed normal to the transparency) traces a straight line along the structure of interest in the image.


Author(s):  
Joseph A. Zasadzinski

At low weight fractions, many surfactant and biological amphiphiles form dispersions of lamellar liquid crystalline liposomes in water. Amphiphile molecules tend to align themselves in parallel bilayers which are free to bend. Bilayers must form closed surfaces to separate hydrophobic and hydrophilic domains completely. Continuum theory of liquid crystals requires that the constant spacing of bilayer surfaces be maintained except at singularities of no more than line extent. Maxwell demonstrated that only two types of closed surfaces can satisfy this constraint: concentric spheres and Dupin cyclides. Dupin cyclides (Figure 1) are parallel closed surfaces which have a conjugate ellipse (r1) and hyperbola (r2) as singularities in the bilayer spacing. Any straight line drawn from a point on the ellipse to a point on the hyperbola is normal to every surface it intersects (broken lines in Figure 1). A simple example, and limiting case, is a family of concentric tori (Figure 1b).To distinguish between the allowable arrangements, freeze fracture TEM micrographs of representative biological (L-α phosphotidylcholine: L-α PC) and surfactant (sodium heptylnonyl benzenesulfonate: SHBS)liposomes are compared to mathematically derived sections of Dupin cyclides and concentric spheres.


Author(s):  
Norman L. Dockum ◽  
John G. Dockum

Ultrastructural characteristics of fractured human enamel and acid-etched enamel were compared using acetate replicas shadowed with platinum and palladium. Shadowed replications of acid-etched surfaces were also obtained by the same method.Enamel from human teeth has a rod structure within which there are crystals of hydroxyapatite contained within a structureless organic matrix composed of keratin. The rods which run at right angles from the dentino-enamel junction are considered to run in a straight line perpendicular to the perimeter of the enamel, however, in many areas these enamel rods overlap, interlacing and intertwining with one another.


1994 ◽  
Vol 39 (2) ◽  
pp. 214-215
Author(s):  
Volker Thomas
Keyword(s):  

1877 ◽  
Vol 4 (86supp) ◽  
pp. 1364-1365
Keyword(s):  

Author(s):  
Akane SETO ◽  
Aleksandar SHURBEVSKI ◽  
Hiroshi NAGAMOCHI ◽  
Peter EADES

2019 ◽  
Vol 47 (2) ◽  
pp. 118-140
Author(s):  
Artem Kusachov ◽  
Fredrik Bruzelius ◽  
Mattias Hjort ◽  
Bengt J. H. Jacobson

ABSTRACT Commonly used tire models for vehicle-handling simulations are derived from the assumption of a flat and solid surface. Snow surfaces are nonsolid and may move under the tire. This results in inaccurate tire models and simulation results that are too far from the true phenomena. This article describes a physically motivated tire model that takes the effect of snow shearing into account. The brush tire model approach is used to describe an additional interaction between the packed snow in tire tread pattern voids with the snow road surface. Fewer parameters and low complexity make it suitable for real-time applications. The presented model is compared with test track tire measurements from a large set of different tires. Results suggest higher accuracy compared with conventional tire models. Moreover, the model is also proven to be capable of correctly predicting the self-aligning torque given the force characteristics.


1979 ◽  
Vol 7 (1) ◽  
pp. 31-39
Author(s):  
G. S. Ludwig ◽  
F. C. Brenner

Abstract An automatic tread gaging machine has been developed. It consists of three component systems: (1) a laser gaging head, (2) a tire handling device, and (3) a computer that controls the movement of the tire handling machine, processes the data, and computes the least-squares straight line from which a wear rate may be estimated. Experimental tests show that the machine has good repeatability. In comparisons with measurements obtained by a hand gage, the automatic machine gives smaller average groove depths. The difference before and after a period of wear for both methods of measurement are the same. Wear rates estimated from the slopes of straight lines fitted to both sets of data are not significantly different.


1979 ◽  
Vol 7 (1) ◽  
pp. 3-13
Author(s):  
F. C. Brenner ◽  
A. Kondo

Abstract Tread wear data are frequently fitted by a straight line having average groove depth as the ordinate and mileage as the abscissa. The authors have observed that the data points are not randomly scattered about the line but exist in runs of six or seven points above the line followed by the same number below the line. Attempts to correlate these cyclic deviations with climatic data failed. Harmonic content analysis of the data for each individual groove showed strong periodic behavior. Groove 1, a shoulder groove, had two important frequencies at 40 960 and 20 480 km (25 600 and 12 800 miles); Grooves 2 and 3, the inside grooves, had important frequencies at 10 240, 13 760, and 20 480 km (6400, 8600, and 12 800 miles), with Groove 4 being similar. A hypothesis is offered as a possible explanation for the phenomenon.


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