scholarly journals The Effect of Grape Seed Extract on t he Pancreatic Weight in Diabetic Rats

2021 ◽  
Vol 17 (4) ◽  
pp. 293-297
Author(s):  
Elif Gülbahçe Mutlu ◽  
Emine Arslan ◽  
Hilal Arıkoğlu ◽  
Salih Varol
Keyword(s):  
Grape Seed Extract ◽  
Grape Seed ◽  
Diabetic Rats ◽  
Seed Extract

scholarly journals The Effects of Grape Seed Extract on Insulin, Adiponectin and Resistin Levels in Diabetic Rats

2021 ◽  
Vol 9 (4) ◽  
pp. 709-713
Author(s):  
İnci Söğütlü ◽  
Nihat Mert ◽  
Handan Mert ◽  
Leyla Mis ◽  
Halil Cumhur Yılmaz ◽  
...  
Keyword(s):  
Insulin Level ◽  
Grape Seed Extract ◽  
Grape Seed ◽  
Diabetic Rats ◽  
Seed Extract ◽  
Control Group ◽  
Albino Rats ◽  
Diabetes Group ◽  
Positive Effects ◽  
Wistar Albino Rats

In this study, the effects of grape seed extract on insulin, adiponectin and resistin levels in diabetic rats were aimed to investigate. Weight of about 300-350g 7-8 weeks 32 female Wistar Albino rats were used. Weight of about 300-350g 7-8 weeks 32 female Wistar Albino rats randomly divided into four groups of eight each: control group (C), group with diabetes (DM), grape seed extract group (GSE), diabetes mellitus and grape seed extract group (DM+GSE). The diabetic group 45 mg/kg single dose of streptozotocin was administered intraperitoneally, and the grape seed extract groups (DM+GSE and GSE) grape seed extract was given orally every day with an intragastric tube for 20 days (0.6 ml/rat). Blood samples were taken from the hearts of rat’s end of the experiment. The sera obtained were used for insulin, adiponectin and resistin analysis measured via ELISA with commercial kits. The insulin and adiponectin levels of the rats in the diabetes + grape seed extract group were found to be higher than those in the diabetes group. There was no significant change in the resistin level differences between the groups. As a result; It is possible to say that grape seed extract has an increasing effect on insulin level and adiponectin levels of diabetic rats are decreased due to diabetes and it has no significant effect on resistin levels. Detected by the positive effects of grape seed extracts, it may be useful to use for the regulating of the diabetes in human.

Grape seed extract has superior beneficial effects than vitamin E on oxidative stress and apoptosis in the hippocampus of streptozotocin induced diabetic rats

Gene ◽  
2015 ◽  
Vol 555 (2) ◽  
pp. 119-126 ◽  
Author(s):  
Goksin Nilufer Yonguc ◽  
Yavuz Dodurga ◽  
Esat Adiguzel ◽  
Gulsah Gundogdu ◽  
Vural Kucukatay ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Vitamin E ◽  
Grape Seed Extract ◽  
Grape Seed ◽  
Diabetic Rats ◽  
Seed Extract ◽  
Beneficial Effects

scholarly journals Effects of grape seed extract on oxidative stress and antioxidant defensemarkers in streptozotocin-induced diabetic rats

2015 ◽  
Vol 45 ◽  
pp. 489-495 ◽  
Author(s):  
Muaz BELVİRANLI ◽  
Hakkı GÖKBEL ◽  
Nilsel OKUDAN ◽  
Sadık BÜYÜKBAŞ
Keyword(s):  
Oxidative Stress ◽  
Grape Seed Extract ◽  
Grape Seed ◽  
Diabetic Rats ◽  
Seed Extract

Grape Seeds Extract as Brain Food: A Review

2017 ◽  
Vol 9 (1) ◽  
Author(s):  
Souad El Gengaihi ◽  
Doha H. Abou Baker
Keyword(s):  
Antioxidant Activities ◽  
Complex Mixture ◽  
Grape Seed Extract ◽  
Grape Seed ◽  
Seed Extract ◽  
Amyloid Peptide ◽  
Grape Seeds ◽  
Potential Benefits ◽  
Reduced Risk

Interest in the biological role of bioactive compounds present in medicinal herbs has increased over the last years. Of particular interest are plants that have an anti-Alzheimer activities. Several plants can be useful for Alzheimer (AD) management. Such as these which have anti-inflammatory activity, acetylcholinesterase (AChE) inhibitory action, antiapoptotic, slow the aggregation of amyloid peptide and antioxidant activities. Grape seed extract (GSE) is a complex mixture of several compounds, mostly represented by polyphenols and flavonoids. Their consumption is safe and is recognized to exert several health benefits. GS flavonoids have been associated with the reduced risk of chronic diseases, we present some findings on the potential benefits of GSE for the treatment of AD.

Grape Seed Extract Complex (FFM-GS) Inhibits Postmenopausal Symptoms: In Vitro and In Vivo S

2019 ◽  
Vol 48 (3) ◽  
pp. 297-305
Author(s):  
Minhee Lee ◽  
Da-Eun Nam ◽  
Soo-Jeung Park ◽  
Dakyung Kim ◽  
Jeong-Moon Yun ◽  
...  
Keyword(s):  
Grape Seed Extract ◽  
Grape Seed ◽  
Seed Extract ◽  
Postmenopausal Symptoms

scholarly journals Comparative Evaluation of Immediate Bond Strength to Bleached Enamel Following Application of Various Antioxidant Solutions

2017 ◽  
Vol 05 (02) ◽  
pp. 084-089
Author(s):  
Alisha Dhingra ◽  
Ashu Gupta ◽  
Anshu Minocha ◽  
Nayantara Sen
Keyword(s):  
Bond Strength ◽  
Shear Bond Strength ◽  
Grape Seed Extract ◽  
Grape Seed ◽  
Seed Extract ◽  
The Other ◽  
Sodium Ascorbate ◽  
Group V ◽  
Group I ◽  
Significant Difference

Abstract Aim: The aim of this study was to compare the reversal of shear bond strength of composite to bleached enamel immediately after bleaching followed by application of various antioxidant solutions. Material and Methods: Seventy central incisors were divided into seven groups. Groups I and II served as unbleached and bleached controls respectively. Groups III, IV, V, VI and VII served as the experimental groups and were subjected to 37.5% hydrogen peroxide bleaching followed by 10 min application of 10% sodium ascorbate, 25% alpha-tocopherol, 6.5% grape seed extract, 5% lycopene and 5% green tea extract respectively. Following composite bonding, shear bond strength was determined and the results were analyzed using ANOVA followed by Post Hoc Multiple Comparisons test. Results: The bond strength values for Group I (positive control) were maximum and significantly different than all the other groups except Grape seed extract group (Group V). When compared to Group II (bleached control), all the groups showed significantly higher bond strength. Significant difference in the bond strength values were seen between Group III (10% sodium ascorbate) and Group V. Also values for Group V were significantly different from Group VI (5% lycopene). All the other values showed insignificantly different results. Conclusion: All the antioxidant solutions improved the shear bond strength values after bleaching but only Grape seed extract application reversed the values to the non bleached levels. Lycopene was least effective. Other antioxidants showed comparable results.

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