scholarly journals Alchornea floribunda (Müll. Arg.) - A review of its phytochemistry and biological activities

2020 ◽  
Vol 19 (5) ◽  
pp. 1113-1120
Author(s):  
Matthias O Agbo ◽  
Festus B.C. Okoye ◽  
Godwin C. Ebi ◽  
Patience O. Osadebe
Keyword(s):  
Antibacterial Activity ◽  
Pharmacological Activity ◽  
Biological Activities ◽  
Bioactive Constituents ◽  
Anti Cancer ◽  
The Family

Alchornea floribunda is an evergreen plant that grows up to 32 feet tall and belongs to the family of Euphorbiaceae. It is found mainly in African forest undergrowth. In Nigeria, its leaves, stems and roots are widely used in folkloric medicine to manage ailments and diseases. The pharmacological activity of A. floribunda depends mainly on the part used. A previous study showed that the leaves have antiinflammatory, antimicrobial, antioxidant and anti-cancer activities, while its roots and stem possess antibacterial activity. Thus, this review takes a critical look at previously reported findings and information about the phytochemistry, biological activities and various isolated bioactive constituents from the leaf, root and stem of Alchornea floribunda. Keywords: Alchornea floribunda, Phytochemistry, Inflammatory, Antimicrobial, Antioxidant, Anti-cancer

Alchornea floribunda (Müll. Arg.), Phytochemistry and Biological Activities: A Review

2018 ◽  
Author(s):  
Matthias Onyebuchi Agbo ◽  
Festus Basden Chiedu Okoye ◽  
Godwin Chukwu Ebi ◽  
Patience Ogoamaka Osadebe
Keyword(s):  
Antibacterial Activity ◽  
Pharmacological Activity ◽  
Biological Activities ◽  
Bioactive Constituents ◽  
Anti Cancer ◽  
The Family ◽  
Anti Inflammatory

Alchornea floribunda is a small evergreen plant that grows up to 32 feet tall. It belongs to the family of Euphorbiaceae and is found mainly in African forest undergrowth. In Nigeria it’s leaves, stems and roots are widely used in folkloric medicine in the management of many ailments and diseases. The pharmacological activity of A. floribunda depends mainly on the part used. The leaves have been documented to possess anti-inflammatory, antimicrobial, antioxidant and anti-cancer activities while the roots and stems have been reported to possess antibacterial activity. Thus, this review summarizes all the findings and information about the phytochemistry, biological activities and various isolated bioactive constituents from the leaves, roots and stems of Alchornea floribunda.

scholarly journals A Review of the Phytochemistry, Traditional Uses and Antibacterial Potential of Psidium guajava

2021 ◽  
Vol 10 (3) ◽  
pp. 2506-2514
Keyword(s):  
Biological Activities ◽  
Psidium Guajava ◽  
New Drugs ◽  
Bioactive Constituents ◽  
Traditional Uses ◽  
The Family ◽  
Pharmacological Studies ◽  
Reliable Knowledge ◽  
Important Drug ◽  
Antibacterial Potential

Psidium guajava is a tropical evergreen tree. It belongs to the family Myrtaceae that consists of about 133 genera and approximately 3800 species worldwide. This plant is mainly found in South Africa, North Africa, South America, and Southeast Asia. Psidium guajava is mainly a nutritional plant, but it also shows various biological activities. An array of bioactive constituents, viz; glycosides, terpenoids, tannins, alkaloids, steroids, saponins, amino acids, anthraquinones, proteins, flavonoids, and phenols, etc. have been isolated from Psidium guajava. These phytochemicals are well known for their biological activities, including antibacterial, antioxidant, antifungal, etc. The present work has been performed to gather data about the traditional uses, important phytochemicals, and antibacterial efficiency of Psidium guajava. Many pharmacological studies have demonstrated its antibacterial potential against various important drug resistive pathogens. We invite researchers' attention to carry out detailed antibacterial studies on this valuable plant species to provide reliable knowledge to the patients and discover more novel compounds for the development of new drugs with fewer side effects compared to conventional medicines.

scholarly journals Erythrina suberosa: Ethnopharmacology, Phytochemistry and Biological Activities

Medicines ◽  
2019 ◽  
Vol 6 (4) ◽  
pp. 105 ◽  
Author(s):  
Felicia Patti ◽  
Yasaman Taheri ◽  
Javad Sharifi-Rad ◽  
Miquel Martorell ◽  
William C. Cho ◽  
...  
Keyword(s):  
Southeast Asia ◽  
Pharmacological Activity ◽  
Biological Activities ◽  
Deciduous Tree ◽  
Pharmacological Properties ◽  
Bioactive Components ◽  
Food Energy ◽  
Ornamental Tree ◽  
The Family ◽  
Coral Tree

Plants are a great and irreplaceable source of medicines, fuel, food, energy and even cosmetics. Since prehistory, humans have learned to use plants for survival, growth and proliferation and still today it relies on natural and cultivated vegetables for food and the source of novel compounds with pharmacological activity. Not only herbs and flowers, but also trees are used. Indeed, Erythrina suberosa Roxb. is a deciduous tree of the family Fabaceae, common in Southeast Asia. In India, E. suberosa is called the “corky coral tree” or simply the “Indian coral tree”, given its peculiar red-orange flowers that can flower throughout the year and its corky irregular bark covered by prickles. It is a plant commonly used as an ornamental tree, but it also holds ethnopharmacological and socioeconomic uses. This article explored phytobiological features of E. suberosa, analysing its taxonomy, examining its traditional and common uses and investigating its bioactive components and pharmacological properties.

Licorice a Supernatural Herb for Healthy Life: Bioactive Phytochemicals and Biological activities – A Review

2019 ◽  
pp. 34-40
Author(s):  
Rozina Aslam ◽  
Misbah Aslam ◽  
Shawana Abdullah ◽  
Muhammad Sarwar Yaqub
Keyword(s):  
Phenolic Compounds ◽  
Biological Activities ◽  
Chewing Gum ◽  
Biological Functions ◽  
Bioactive Constituents ◽  
Healthy Life ◽  
Chemopreventive Agents ◽  
Anti Cancer ◽  
Bioactive Phytochemicals ◽  
Anti Inflammation

Licorice, a medicinal herb, has been found to contain various phytochemicals including flavonoids, phenolic compounds, saponins, sapogenins, pterocarpenes, coumestan derivatives, 2-arylobenzofuran derivatives, chemopreventive agents, acidic constituents and glycyrrhizin having different biological activities. Licorice is used in medical for treatment of various diseases like atherosclerosis, osteoporosis and Alzheimer’s disease. It is used as anti-inflammation, anti-ulcer, anti-cancer, anti-virus and in many other problems. It is also used as additive for flavoring candies, chewing gum and toothpaste. The roots of this plant are majorly used for extracting different phytochemicals. Various licorice species: Glycyrrhiza glabra, G. uralensis, G. inflata, G. lepidota, and G. pallidiflora contain various phytochemicals with different type of biological activities. This paper provides a brief of the bioactive constituents and biological functions of different licorice species in details.

scholarly journals An Ethnopharmacological, Phytochemical and Pharmacological Review on Lignans from Mexican Bursera spp.

Molecules ◽  
2018 ◽  
Vol 23 (8) ◽  
pp. 1976 ◽  
Author(s):  
Maria Marcotullio ◽  
Massimo Curini ◽  
Judith Becerra
Keyword(s):  
Biological Activities ◽  
Phenolic Metabolites ◽  
Anti Cancer ◽  
The Family ◽  
Anti Inflammatory ◽  
Anti Fungal

The genus Bursera belongs to the family Burseraceae and has been used in traditional Mexican medicine for treating various pathophysiological disorders. The most representative phytochemicals isolated from this genus are terpenoids and lignans. Lignans are phenolic metabolites known for their antioxidant, apoptotic, anti-cancer, anti-inflammatory, anti-bacterial, anti-viral, anti-fungal, and anti-protozoal properties. Though the genus includes more than 100 species, we have attempted to summarize the biological activities of the 34 lignans isolated from selected Mexican Bursera plants.

scholarly journals Cordyceps spp.: A Review on Its Immune-Stimulatory and Other Biological Potentials

2021 ◽  
Vol 11 ◽  
Author(s):  
Gitishree Das ◽  
Han-Seung Shin ◽  
Gerardo Leyva-Gómez ◽  
María L. Del Prado-Audelo ◽  
Hernán Cortes ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Bioactive Compounds ◽  
Cyclic Peptides ◽  
Biological Activities ◽  
Mitogen Activated Protein Kinase ◽  
Special Focus ◽  
Phytochemical Analysis ◽  
Bioactive Constituents ◽  
Anti Cancer ◽  
Stimulation Of

In recent decades, interest in the Cordyceps genus has amplified due to its immunostimulatory potential. Cordyceps species, its extracts, and bioactive constituents have been related with cytokine production such as interleukin (IL)-1β, IL-2, IL-6, IL-8, IL-10, IL-12, and tumor necrosis factor (TNF)-α, phagocytosis stimulation of immune cells, nitric oxide production by increasing inducible nitric oxide synthase activity, and stimulation of inflammatory response via mitogen-activated protein kinase pathway. Other pharmacological activities like antioxidant, anti-cancer, antihyperlipidemic, anti-diabetic, anti-fatigue, anti-aging, hypocholesterolemic, hypotensive, vasorelaxation, anti-depressant, aphrodisiac, and kidney protection, has been reported in pre-clinical studies. These biological activities are correlated with the bioactive compounds present in Cordyceps including nucleosides, sterols, flavonoids, cyclic peptides, phenolic, bioxanthracenes, polyketides, and alkaloids, being the cyclic peptides compounds the most studied. An organized review of the existing literature was executed by surveying several databanks like PubMed, Scopus, etc. using keywords like Cordyceps, cordycepin, immune system, immunostimulation, immunomodulatory, pharmacology, anti-cancer, anti-viral, clinical trials, ethnomedicine, pharmacology, phytochemical analysis, and different species names. This review collects and analyzes state-of-the-art about the properties of Cordyceps species along with ethnopharmacological properties, application in food, chemical compounds, extraction of bioactive compounds, and various pharmacological properties with a special focus on the stimulatory properties of immunity.

scholarly journals Sinapic Acid and Sinapate Esters in Brassica: Innate Accumulation, Biosynthesis, Accessibility via Chemical Synthesis or Recovery From Biomass, and Biological Activities

2021 ◽  
Vol 9 ◽  
Author(s):  
V. P. Thinh Nguyen ◽  
Jon D. Stewart ◽  
Irina Ioannou ◽  
Florent Allais
Keyword(s):  
Chemical Synthesis ◽  
Biological Activities ◽  
Sinapic Acid ◽  
Industrial Wastes ◽  
Biological Processes ◽  
In Planta ◽  
Food Industries ◽  
Plant Parts ◽  
Anti Cancer ◽  
The Family

Sinapic acid (SinA) and corresponding esters are secondary metabolites abundantly found in plants of Brassica family. Belonging to the family of p-hydroxycinnamic acids, SinA and its esters analogues are present in different plant parts and involved in multiple biological processes in planta. Moreover, these metabolites are also found in relatively large quantities in agro-industrial wastes. Nowadays, these metabolites are increasingly drawing attention due to their bioactivities which include antioxidant, anti-microbial, anti-cancer and UV filtering activities. As a result, these metabolites find applications in pharmaceutical, cosmetic and food industries. In this context, this article reviews innate occurrence, biosynthesis, accessibility via chemical synthesis or direct extraction from agro-industrial wastes. Biological activities of SinA and its main corresponding esters will also be discussed.

ANTICANCER EFFECT OF UVARIA GENUS

2014 ◽  
pp. 98-101
Author(s):  
Thi Bich Hien Le ◽  
Viet Duc Ho ◽  
Thi Hoai Nguyen
Keyword(s):  
Biological Activities ◽  
Current Trend ◽  
Healthcare Systems ◽  
Chemical Compositions ◽  
Cancer Therapies ◽  
Pharmacological Effects ◽  
Anticancer Effect ◽  
Anti Cancer ◽  
Tropical Areas ◽  
Cancer Activity

Nowadays, cancer treatment has been a big challenge to healthcare systems. Most of clinical anti-cancer therapies are toxic and cause adverse effects to human body. Therefore, current trend in science is seeking and screening of natural compounds which possess antineoplastic activities to utilize in treatment. Uvaria L. - Annonaceae includes approximately 175 species spreading over tropical areas of Asia, Australia, Africa and America. Studies on chemical compositions and pharmacological effects of Uvaria showed that several compound classes in this genus such as alkaloid, flavonoid, cyclohexen derivaties, acetogenin, steroid, terpenoid, etc. indicate considerable biological activities, for example anti-tumor, anti-cancer, antibacterial, antifungal, antioxidant, etc. Specifically, anti-cancer activity of fractions of extract and pure isolated compounds stands out for cytotoxicity against many cancer cell lines. This study provides an overview of anti-cancer activity of Uvaria and suggests a potential for further studies on seeking and developing novel anti-cancer compounds. Key words: Anti-cancer, Uvaria.

Current Advances in the Biological Activity of Polysaccharides in Dendrobium with Intriguing Therapeutic Potential

2018 ◽  
Vol 25 (14) ◽  
pp. 1663-1681 ◽  
Author(s):  
Chun-Ting Lee ◽  
Heng-Chun Kuo ◽  
Yung-Hsiang Chen ◽  
Ming-Yen Tsai
Keyword(s):  
Biological Activity ◽  
Therapeutic Potential ◽  
Biological Activities ◽  
Biological Effects ◽  
Herbal Medicines ◽  
Research Field ◽  
Protective Effects ◽  
Pharmacological Effects ◽  
The Family ◽  
Anti Tumor Activity

The polysaccharides in many plants are attracting worldwide attention because of their biological activities and medical properties, such as anti-viral, anti-oxidative, antichronic inflammation, anti-hypertensive, immunomodulation, and neuron-protective effects, as well as anti-tumor activity. Denodrobium species, a genus of the family orchidaceae, have been used as herbal medicines for hundreds of years in China due to their pharmacological effects. These effects include nourishing the Yin, supplementing the stomach, increasing body fluids, and clearing heat. Recently, numerous researchers have investigated possible active compounds in Denodrobium species, such as lectins, phenanthrenes, alkaloids, trigonopol A, and polysaccharides. Unlike those of other plants, the biological effects of polysaccharides in Dendrobium are a novel research field. In this review, we focus on these novel findings to give readers an overall picture of the intriguing therapeutic potential of polysaccharides in Dendrobium, especially those of the four commonly-used Denodrobium species: D. huoshanense, D. offininale, D. nobile, and D. chrysotoxum.

Structure-Bioactivity Relationship Study of Xanthene Derivatives: A Brief Review

2020 ◽  
Vol 16 (8) ◽  
pp. 1071-1077
Author(s):  
Aref G. Ghahsare ◽  
Zahra S. Nazifi ◽  
Seyed M.R. Nazifi
Keyword(s):  
Biological Activities ◽  
Cyclic Compound ◽  
Research Field ◽  
Pharmaceutical Chemistry ◽  
Therapeutic Effects ◽  
Main Research ◽  
Research Fields ◽  
Xanthene Derivatives ◽  
Anti Cancer ◽  
Heterocyclic Derivatives

: Over the last decades, several heterocyclic derivatives compounds have been synthesized or extracted from natural resources and have been tested for their pharmaceutical activities. Xanthene is one of these heterocyclic derivatives. These compounds consist of an oxygen-containing central heterocyclic structure with two more cyclic structures fused to the central cyclic compound. It has been shown that xanthane derivatives are bioactive compounds with diverse activities such as anti-bacterial, anti-fungal, anti-cancer, and anti-inflammatory as well as therapeutic effects on diabetes and Alzheimer. The anti-cancer activity of such compounds has been one of the main research fields in pharmaceutical chemistry. Due to this diverse biological activity, xanthene core derivatives are still an attractive research field for both academia and industry. This review addresses the current finding on the biological activities of xanthene derivatives and discussed in detail some aspects of their structure-activity relationship (SAR).

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