Five Differing Organizational Structures And Levels: Stepping Stones Toward Greater Success, Productivity And Profitability!

2020 ◽  
pp. 51-56
Author(s):  
Jeffrey L. Magee
Author(s):  
Evelyn M. Ryan ◽  
Edward W. Russell

Many differences exist in Department of Energy (DOE) and Nuclear Regulatory Commission (NRC) Quality Assurance (QA) requirements documents, work scope, organizational structures, and graded application and assessment approaches. These differences must be understood and reconciled to ensure consistent and effective implementation and cost effective assessments of QA Programs for DOE organizations participating in the design, purchase, fabrication, handling, shipping, storing, cleaning, assembly, inspection, testing, operation, maintenance, repair, use and/or modification of the radioactive material packaging. This paper discusses those differences and provides practical recommendations that can serve as stepping stones to more effective and efficient QA programs and value added assessments at DOE sites participating in radioactive material packaging activities.


2020 ◽  
Vol 477 (16) ◽  
pp. 3091-3104 ◽  
Author(s):  
Luciana E. Giono ◽  
Alberto R. Kornblihtt

Gene expression is an intricately regulated process that is at the basis of cell differentiation, the maintenance of cell identity and the cellular responses to environmental changes. Alternative splicing, the process by which multiple functionally distinct transcripts are generated from a single gene, is one of the main mechanisms that contribute to expand the coding capacity of genomes and help explain the level of complexity achieved by higher organisms. Eukaryotic transcription is subject to multiple layers of regulation both intrinsic — such as promoter structure — and dynamic, allowing the cell to respond to internal and external signals. Similarly, alternative splicing choices are affected by all of these aspects, mainly through the regulation of transcription elongation, making it a regulatory knob on a par with the regulation of gene expression levels. This review aims to recapitulate some of the history and stepping-stones that led to the paradigms held today about transcription and splicing regulation, with major focus on transcription elongation and its effect on alternative splicing.


Author(s):  
Alice Welbourn ◽  
Florence Kilonzo ◽  
T.J. Mboya ◽  
Shoba Mohamed Liban
Keyword(s):  

2017 ◽  
Vol 1 (1) ◽  
pp. 1-6 ◽  
Author(s):  
Franca Angela Buelow

To arrive at a good status of all European water bodies is the main objective of the European Union (EU) Water Framework Directive (WFD). Since its adoption in 2000, the policy has fundamentally changed the institutional, procedural and organizational structures of Member States' water management, leading to an Europeanization of national legislation and decision-making structures. The case of WFD implementation in Schleswig-Holstein is an example of the policy's highly innovative governance architecture that unfortunately is not (yet) able to take that one last hurdle: to improve water quality and establish a good water status across EU Member States by 2015 or 2027.


2020 ◽  
Vol 26 (1) ◽  
pp. 151-156
Author(s):  
Andrei Șandor

AbstractSince the emergence of Internet and social media, new Intelligence branches have flourished, like CYBERINT (Cyber Intelligence), OSINT (Open Source Intelligence) or SOCMINT (Social Media Intelligence), with the aim to exploit different dimensions of the virtual world. These Intelligence-related disciplines may inquire personal information, statements and conversations posted voluntarily on websites or social platforms in order to profile people, identify social networks and organizational structures, and uncover vulnerabilities and threats/risks that can jeopardize the security of individuals or organizations. In this respect, the Internet - as environment - can provide valuable information from both technical and social side. This is why the World Wide Web is and will remain an important place to search for data and information that can be processed into Intelligence, and represents the reason why people working in sensitive domains (e.g. Intelligence) should be aware of their vulnerabilities and the risks and threats posed by this environment.DISCLAIMER: This paper expresses the views, interpretations, and independent position of the authors. It should not be regarded as an official document, nor expressing formal opinions or policies, of NATO or the HUMINT Centre of Excellence.


2018 ◽  
Vol 6 (1) ◽  
pp. 5-21
Author(s):  
Ewa Skrabacz

AbstractConstituting the key element of a democratic system, political parties are among entities obliged by the Polish legislator to comply with the principle of disclosure by providing public information. The main objective of this paper is to determine the level of Polish political parties’ disclosure, understood here as their willingness to disclose information on their own structures. It seems that the practice of disclosing such basic organizational data may constitute a specific measure of Polish political parties’ respect for the idea of disclosure. The subject matter of the conducted research was particular parties’ sites in the Public Information Bulletin as well as their official websites. An attempt was made to acquire data concerning party structures by way of direct contact with particular parties’ organizational units – questionnaires were sent to both central and regional/district organizational units. In order to acquire a wider perspective, the research also included data provided by the Central Statistical Office concerning political parties’ organizational structures and election manifestos. The conducted analysis was summarized in the form of a ranking of the examined political parties based on a proposed political party disclosure index. This attempt to measure disclosure on the basis of data on internal structures provided by parties themselves is of a preliminary character which, nevertheless, makes it possible to capture the general properties of the phenomenon under analysis. Among the examined parties, it is PSL, SLD, and PO that, to an acceptable degree, follow the principle of disclosure in the analysed scope (indexes at the level of 60%-80% of the maximum value). Four other parties, i.e. N, Wolność, Razem, and Kukiz’15, are on the edge of the zone making it possible to regard their disclosure as sufficient (indexes at the level of around 50% of the maximum value). In the case of PiS, whose index does not reach 20% of the maximum value, it should be concluded that this party implements the principle of disclosure at a minimum level. The ranking did not show relationships between parties’ willingness towards providing information and their sizes or positions on the political scene (parliamentary parties vs. extra-parliamentary parties).


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