Malaria is currently affecting more people in the world than any other disease. On average, two members of each household suffered from malaria fever monthly, with females and children being most vulnerable to malaria attacks. This chapter assessed communities' perception about malaria epidemic, weather variable and climate change in metropolitan Kano. Information was extracted related to communities' perception about malaria epidemic and climate change. Socio demographic characteristics of respondents in the study areas were extracted and analyzed. 75% of the participants were males, while 25% were females, malaria disease affected 79.66% and 59.66% respondent perceived that heavy rainfall, floods and high temperature are better conditions to the breeding and spread of malaria vectors. Hospital records revealed that Month of March and April (2677 and 2464, respectively) has highest number of malaria cases recorded between December 2010 to June 2011. Further research is recommended for in-depth information from health officials related to raising awareness.