scholarly journals Indoor Air and Surface Fungal Contamination in the Special Care Baby Unit of a Tertiary Hospital in Jos, Nigeria

2020 ◽  
Vol 1 (2) ◽  
pp. 170-175
Author(s):  
OM Okolo ◽  
AB Toma ◽  
AE Envulado ◽  
I Olubukunnola ◽  
A Izang ◽  
...  

Fungi frequently contaminate the indoor air as well as surfaces of hospital equipment and furniture. This pose a significant risk for neonates in the Special Care Baby Unit. This study aimed to determine the rate of fungal contamination of indoor air and surfaces of the special care baby unit of a tertiary health facility in Jos, Nigeria. The study was carried out at the special care baby unit of the Jos University Teaching Hospital. Indoor air samples were obtained using sedimentation method whereas samples from surfaces were collected using sterile pre-moistened cotton tipped swab sticks. The swab sticks were inoculated onto sabouraud dextrose agar plates which were incubated along with indoor air culture plates for seven days. Univariate analysis was carried out using STATA (version 14IC). Fungal contamination rate of the special care baby unit was 20.2%.  Aspergillus species (29.6%) was the most predominant fungus isolated. Most of the fungi were isolated from the outborn term and outborn preterm rooms of the special care baby unit. The fungi isolated include Aspergillus spp, Candida spp, Penicillium spp, Cladosporium spp, Curvularia spp, Fusarium spp, Paecillomyces spp, Alternatia spp, and Rhodotorulla spp. Fungi are a major cause of indoor air as well as surface contamination in special care baby unit of the hospital. Routine cleaning and disinfection will lead to a reduction in the fungal load.

2021 ◽  
Vol 2 (1) ◽  
pp. 08-013
Author(s):  
Samuel C Ojiakor ◽  
Afam B Obidike ◽  
Kenneth N Okeke ◽  
Chioma P Nnamani ◽  
Amaka L Obi-Nwosu ◽  
...  

Background: Epidural labor analgesia has become prevalent in high income countries, but its use in low and middle income countries such as Nigeria is poorly studied. Objectives: To determine the rate of demand, indications, post-dural puncture headache rate and factors affecting demand for epidural analgesia among women in labor. Method: This was a across sectional analytical study of women in labor who were managed at Nnamdi Azikiwe University Teaching Hospital Nnewi, Nigeria from 1st January 2017 to 31st December 2017. Data was obtained from women’s case files from Medical record department, labor ward, and Anesthesiology departmental records. Information obtained included total number of deliveries, mode of delivery, those that received epidural: date and time of placement, indication and number of side effects. Univariate analysis models were applied to evaluate the association between patient demographic, socioeconomic factors, clinical and demand for labor epidural analgesia. A p-value of <0.05 was taken as significant. Results: Thirty-six women out of 1,373 women received epidural labor analgesia, giving the epidural labor analgesic rate of 2.6%. The most common indication for epidural labor analgesia was maternal voluntary request which accounted for 24 (66.7%) of the population receiving analgesia. One (2.8%) parturient developed post-dural puncture headache which resolved spontaneously within 24 hours. Parturient who utilized labor epidurals were significantly older than 30 years of age (OR 3.16; 95% CI 1.51-6.62; p=0.002), Multi-parous (OR 26.65; 95% CI 3.64-100.00; p=0.001), and with higher income (OR 9.02; 95% CI 4.38-18.57; p=<0.001), but not with higher level of education (OR 0.56; 95% CI 0.27-1.16; p=0.114). Conclusion: The demand for labor epidural in the study center was low with a demand rate of 2.6% and post-dural puncture headache rate of 2.8%. The significant factors related to a parturient’s request for epidural analgesia during labor included age greater than 30 years, multiparity and higher income. There is a need for an enhanced awareness programs on obstetrics epidural analgesia.


2018 ◽  
Vol 08 (02) ◽  
pp. 117-125
Author(s):  
Martha O. Ochoga ◽  
Aondoaseer Michael ◽  
Rose O. Abah ◽  
Othniel Dabit ◽  
Iyornenge Ikuren ◽  
...  

2019 ◽  
Vol 41 (1) ◽  
Author(s):  
Ekaniyere Benlance ◽  
Birch Dauda SAHEEB

Oro-antral perforation (OAP) could be misdiagnosed if the incidence and risk factors are unknown and its consequence could be worrisome. We aimed to determine the incidence and risk factors of oro-antral perforations after teeth extraction. A retrospective study of forceps extracted upper posterior teeth over a ten-year period from September 2008 to November 2018 was done at our hospital in Nigeria. In univariate analysis, the predictors were age, gender, experience of surgeon, site of tooth, side of surgery, use of elevators while the outcome variable was oroantral perforations. Logistic regression was also done to determine the risk factors associated OAP. We used SPSS Version 17(SPSS Inc, Chicago, USA) to perform descriptive and inferential statistical analysis. P-Value less than 0.05 was considered statistically significant. Out of the total 26,372 dental extractions during the ten-year period, 54 (0.2%) extraction cases (33 males, 21 females) had oro-antral perforations. Their mean age was 54.8± 10.6years (ranging from 21 to78 years). The highest incidence occurred in the sixth decade of life. Only the location of teeth had a significant association with oro-antral perforations. The location of upper first molar was (OR = 1.85, P=0.00) identified as a significant risk factor. The incidence of OAP is significantly lower in Nigerians and was 0.2% although there could be a population variability. The position of the upper first molar was a factor found to be associated and predictive of the OAP but age, gender, number of extractions per visit, side of operation and the surgeon’s experience were not. The findings will help surgeons to predict occurrence of OAP knowing its risk factors.


2021 ◽  
Vol 2 (1) ◽  
pp. 9-16
Author(s):  
M O Ochoga ◽  
E E Eseigbe ◽  
A M Onoja ◽  
M Aondoaseer ◽  
B N Samba ◽  
...  

Blood transfusion is a life-saving procedure in which whole blood or parts of blood are introduced into a patient's bloodstream intravenously. The need maybe due to physiological or pathological causes. The objective of this study was to document the pattern and indications for blood transfusion at the Special Care Baby Unit of the Benue State University Teaching Hospital (BSUTH), Makurdi. This study was a retrospective review of 126 neonates who received blood transfusion at the Special care baby unit of BSUTH from 1st January 2015 to 31st December 2019. Data was retrieved from patient's medical records and analyzed using IBM SPSS version 23. A total of 1142 neonates were admitted over the study period and 126 had blood transfusion giving a prevalence of 11.0%. Male/Female ratio of 1.57:1.Mean (±SD) Birth weight and gestational age (GA) were 2.23±0.82Kg and 35.48 ±3.95 weeks respectively. Exchange blood transfusion was the most frequent 53(42.1%) type of blood transfusion. The most common indications for blood transfusion were anaemia of prematurity, sepsis and severe neonatal jaundice. A hundred and twelve (88.9%) who received transfusion were discharged while 4(3.2%) died. The rate of blood transfusion was low, while severe neonatal jaundice and anaemia were the main indications for blood transfusion in this study. Exchange blood transfusion was the main type of transfusion.


Medicina ◽  
2021 ◽  
Vol 57 (5) ◽  
pp. 420
Author(s):  
Claudia Ioana Borțea ◽  
Florina Stoica ◽  
Marioara Boia ◽  
Emil Radu Iacob ◽  
Mihai Dinu ◽  
...  

Background and Objectives: Retinopathy of prematurity (ROP) is the leading cause of blindness in preterm infants. We studied the relationship between different perinatal characteristics, i.e., sex; gestational age (GA); birth weight (BW); C-reactive protein (CRP) and lactate dehydrogenase (LDH) concentrations; ventilation, continuous positive airway pressure (CPAP), and surfactant administration; and the incidence of Stage 1–3 ROP. Materials and Methods: This study included 247 preterm infants with gestational age (GA) < 32 weeks that were successfully screened for ROP. Univariate and multivariate binary analyses were performed to find the most significant risk factors for ROP (Stage 1–3), while multivariate multinomial analysis was used to find the most significant risk factors for specific ROP stages, i.e., Stage 1, 2, and 3. Results: The incidence of ROP (Stage 1–3) was 66.40% (164 infants), while that of Stage 1, 2, and 3 ROP was 15.38% (38 infants), 27.53% (68 infants), and 23.48% (58 infants), respectively. Following univariate analysis, multiple perinatal characteristics, i.e., GA; BW; and ventilation, CPAP, and surfactant administration, were found to be statistically significant risk factors for ROP (p < 0.001). However, in a multivariate model using the same characteristics, only BW and ventilation were significant ROP predictors (p < 0.001 and p < 0.05, respectively). Multivariate multinomial analysis revealed that BW was only significantly correlated with Stage 2 and 3 ROP (p < 0.05 and p < 0.001, respectively), while ventilation was only significantly correlated with Stage 2 ROP (p < 0.05). Conclusions: The results indicate that GA; BW; and the use of ventilation, CPAP, and surfactant were all significant risk factors for ROP (Stage 1–3), but only BW and ventilation were significantly correlated with ROP and specific stages of the disease, namely Stage 2 and 3 ROP and Stage 2 ROP, respectively, in multivariate models.


2019 ◽  
Vol 65 (9) ◽  
pp. 1102-1114 ◽  
Author(s):  
Hiroaki Ikezaki ◽  
Virginia A Fisher ◽  
Elise Lim ◽  
Masumi Ai ◽  
Ching-Ti Liu ◽  
...  

AbstractBACKGROUNDIncreases in circulating LDL cholesterol (LDL-C) and high-sensitivity C-reactive protein (hsCRP) concentrations are significant risk factors for cardiovascular disease (CVD). We assessed direct LDL-C and hsCRP concentrations compared to standard risk factors in the Framingham Offspring Study.METHODSWe used stored frozen plasma samples (−80 °C) obtained after an overnight fast from 3147 male and female participants (mean age, 58 years) free of CVD at cycle 6 of the Framingham Offspring Study. Overall, 677 participants (21.5%) had a CVD end point over a median of 16.0 years of follow-up. Total cholesterol (TC), triglyceride (TG), HDL cholesterol (HDL-C), direct LDL-C (Denka Seiken and Kyowa Medex methods), and hsCRP (Dade Behring method) concentrations were measured by automated analysis. LDL-C was also calculated by both the Friedewald and Martin methods.RESULTSConsidering all CVD outcomes on univariate analysis, significant factors included standard risk factors (age, hypertension, HDL-C, hypertension treatment, sex, diabetes, smoking, and TC concentration) and nonstandard risk factors (non-HDL-C, direct LDL-C and calculated LDL-C, TG, and hsCRP concentrations). On multivariate analysis, only the Denka Seiken direct LDL-C and the Dade Behring hsCRP were still significant on Cox regression analysis and improved the net risk reclassification index, but with modest effects. Discordance analysis confirmed the benefit of the Denka Seiken direct LDL-C method for prospective hard CVD endpoints (new-onset myocardial infarction, stroke, and/or CVD death).CONCLUSIONSOur data indicate that the Denka Seiken direct LDL-C and Dade Behring hsCRP measurements add significant, but modest, information about CVD risk, compared to standard risk factors and/or calculated LDL-C.


2002 ◽  
Vol 29 (3) ◽  
Author(s):  
EF Ugochukwu ◽  
CC Ezechukwu ◽  
CC Agbata ◽  
I Ezumba

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