Management of Male Infertility Caused by Oligospermia Using Ayurveda: A Case Report

In India, 1 out of 10 couples suffers from infertility are owing to impaired spermatozoa production or its function, impaired sperm delivery, improper ejaculation, due to sedentary life styles and day to day stress nowadays. Male infertility can be defined as an inability to induce conception, due to defect in spermatozoic functions like low sperm count, unhealthy sperm production, low sperm motility and altered delivery of sperms due to altered physiology of male reproductive system. A 29-year-old married man was diagnosed with oligospermia, visited Shuddhi Ayurveda Clinics, Noida for his condition management and treated successfully with Ayurvedic drugs. This married couple was facing infertility issue from last 2-3 years. Patient was treated with Ayurvedic drugs and kept on strict diet monitoring for four months and results were counted in terms of improved total sperm count after treatment. Before treatment sperm count was 10 million per ml which got improved up to 90 million per ml after four months of Ayurvedic treatment with strict diet regimen. No any side effects were observed during the treatment period. Other morphological parameters of sperm were also found to be healthy and normal for fertility. From the results of this case report, Ayurvedic treatment is proved to be effective in the treatment of male infertility associated with oligospermia.

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AYURVEDIC MANAGEMENT OF KSHEENA SHUKRA (OLIGOSPERMIA) LEADING TO MALE INFERTILITY: A CASE REPORT

International Journal of Research in Ayurveda and Pharmacy ◽

10.7897/2277-4343.1204101 ◽

2021 ◽

Vol 12 (4) ◽

pp. 30-32

Author(s):

Akhilraj A R ◽

Amalraj A R

Keyword(s):

Case Report ◽

Male Infertility ◽

Conventional Medicine ◽

Sperm Count ◽

Semen Analysis ◽

World Health ◽

Case Discussion ◽

Ayurvedic Treatment ◽

Health Organization

As per the World Health Organization (WHO) report in India, the overall prevalence of primary infertility ranges between 3.9 to 16.8%. A recent report on status of infertility states that, 50% is related to reproductive anomalies or disorders in the male, in which 90% of male infertility problems are related to Oligospermia and other abnormalities in semen analysis. As per Ayurveda, Oligospermia can be considered as Ksheena Shukra. Surgery, Hormone treatments, Medications and Assisted Reproductive Technology (ART) are the main line of treatment in Conventional medicine, but these are associated with many unwanted and serious adverse effects. The present case discussion is about the effective management of a case diagnosed as Ksheena Shukra (Oligospermia) with Ayurvedic intervention, which was posted for ART and Hormone therapy. The aim of this case report is to evaluate the effect of Ayurvedic treatment in the management of Ksheena Shukra. In this case study, Shodhana procedures (especially Virechana karma) were performed before the administration of Rasayana and Vajikarana drugs, which are Narasimha rasayana, Bhringarajasavam, Ashwagandha churna. The pre and post Semen analysis on the treatment period shows, marked increase in sperm count and motility. The outcome of this case reveals that the Oligospermia associated with male infertility can be effectively managed by Ayurvedic treatments.

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Cytomegalovirus infection and male infertility: case report

Andrology and Genital Surgery ◽

10.17650/1726-9784-2021-22-1-85-89 ◽

2021 ◽

Vol 22 (1) ◽

pp. 85-89

Author(s):

V. Р. Kovalyk ◽

V. V. Malinovskaya ◽

A. N. Shuvalov ◽

L. F. Kurilo ◽

К. I. Yurlov ◽

...

Keyword(s):

Case Report ◽

Male Infertility ◽

Cytomegalovirus Infection ◽

Married Couple ◽

Antiviral Treatment ◽

Sperm Concentration ◽

Accessory Gland ◽

Male Factor ◽

Healthy Baby ◽

History Of

Objectives. To present a case report of male infertility associated with cytomegalovirus infection and the outcome of antiviral treatment.Clinical observation. A 31-year-old man presented with a history of 6 years of infertility. No pathology was revealed in his wife. High loads of cytomegalovirus (CMV) were detected by PCR: in expressed prostatic secretion (EPS) 8700 copies/ml, in ejaculate – 598 440 copies/ml. Sperm examination revealed necrozoospermia and leukospermia. CMV-associated accessory gland infection was verified. The patient was treated with valacyclovir 500 bid for 90 days and interferon α2β suppository (Viferon®) 1 million IU for 30 days. All sperm parameters improved in 1 month after initiation of antiviral treatment. Sperm concentration and motility increased × 1.5 and × 1.4 respectively, sperm viability and leukocyte count achieved reference values. At the same time, CMV loads decreased: EPS to 300 copies/ml, the ejaculate to 54 000 copies/ml. After 3 months (by the end of the antiviral treatment): EPS-negative, the ejaculate – 6060 copies/ml; after 6 months: EPS – negative, the ejaculate 3900 copies/ml. Within 6 months, the woman became pregnant and gave birth to a healthy baby girl. After 3 years, there was a second pregnancy and the birth of a healthy boy.Conclusion. The male factor has been established as the cause of infertility in a married couple; the only probable etiological agent of pathozoospermia was cytomegalovirus infection. The use of complex antiviral and immunotherapy (interferon α2β with antioxidants, Viferon®) provided positive dynamics in clinical, sperm and laboratory parameters, which led to the conception and birth of two children.

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MANAGEMENT OF MALE INFERTILITY (OLIGOASTHENOZOOSPERMIA) WITH AYURVEDA

November 2020 - International Ayurvedic Medical Journal ◽

10.46607/iamj5508102020 ◽

2020 ◽

Vol 8 (10) ◽

pp. 4902-4905

Author(s):

Shivani Karnwal

Keyword(s):

Male Infertility ◽

Male Patient ◽

Sperm Count ◽

Semen Analysis ◽

Male Partner ◽

Unprotected Intercourse ◽

Fertile Female ◽

Ayurvedic Drugs ◽

Motility Of Sperm ◽

Diagnostic Investigations

Male infertility refers to a male’s inability to cause pregnancy in a fertile female. There are many reasons that aid the pathology of male infertility primary includes low sperm count, volume, motility, abnormality in shapes and few reproductive dysfunctions. Oligoasthenozoopsermia which is one of the major causes behind male infertility comprises two conditions – Oligospermia (low sperm count) and Asthenozoo-spermia (reduced motility of sperm).Researches reveals that 1 in every 3 cases of infertility are due to the male partner so nowadays diagnosis and management of both the partners is now considered as a vital tool. In this article, I report a case of a 30-year-old male patient with complaints of wanting an issue after a complete year of regular, unprotected intercourse. For which he had undergone all the regular diagnostic investigations of his wife, which reported no issues and recorded with regular and ovulatory cycles with patent tubes. Then progressing in the diagnosis, he had undergone a semen analysis and got diagnosed with Oligoasthenozoospermia. The issue was successfully treated with Ayurvedic drugs within a period of 1 month.

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Contribution of Ayurveda in the Management of Ksheena Shukra Vikara with Special Reference to Asthenozoospermia: A Case Report

Journal of Pharmaceutical Research International ◽

10.9734/jpri/2021/v33i36b31961 ◽

2021 ◽

pp. 140-149

Author(s):

Manju Mohan ◽

Sawarkar Punam ◽

Sawarkar Gaurav

Keyword(s):

Case Report ◽

Male Infertility ◽

Sperm Motility ◽

Clinical Symptoms ◽

Sperm Count ◽

Single Case ◽

Semen Analysis ◽

Male Factor ◽

Sperm Analysis ◽

Patient Reported

Background: Male Infertility is one of the burning issues now a day’s nevertheless disregarded reproductive health problems in India. Incidences of this issue expands day by day because of the disturbing lifestyle pattern. Almost 30-40-% of infertility cases found to be related to male factor. Asthenozoospermia is the most common identifiable anomaly related to male infertility found in semen analysis having reduced motility of sperm. Aim and Objectives: To assess the efficacy of Ayurvedic management (Shodhana and Shamana Chikitsa) in the management of Ksheena Shukra Vikara w.s.r. to Asthenozoospermia. Methods: It is a single case study. A 33-year-old male patient who was already diagnosed with Asthenozoospermia for three years approached to Pancharkarma OPD. Sperm motility was only 12%. The patient was treated with Shodhana Chikitsa (Vamana and Virechana with Mahatiktaka Ghritapana and Dashmooladi Niruha Vasti and Uttarvasti with Vidaryadi Ghrita followed by Shamana Chikitsa (Tab Neo Charak Pharmacy, Tab Addyzoa, Chandraprabha Vati, Paripathadi Kashaya, Ashwagandhadi Yamaka, Avipattikar Churna) approximately 3 months. After 3 months, patient-reported improvement. Results: Assessment of the patient with clinical symptoms and sperm analysis report was done following 3 months. Sperm motility increased up to 40% with increment in sperm count. Conclusion: This case report provides us a guideline that infertility associated with Asthenozoospermia can be treated successfully by adopting basic Ayurveda Siddhanta's.

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MANAGEMENT OF FEMALE INFERTILITY DUE TO TUBAL BLOCKAGE BY AYURVEDIC TREATMENT PROTOCOL: A CASE REPORT

November 2020 - International Ayurvedic Medical Journal ◽

10.46607/iamj3708112020 ◽

2020 ◽

Vol 08 (11) ◽

pp. 5181-5184

Author(s):

Amisha H. Dholariya ◽

Dei L. P. ◽

Donga S. B.

Keyword(s):

Case Report ◽

Male Infertility ◽

Embryo Transfer ◽

Treatment Protocol ◽

Present Case Report ◽

Tubal Blockage ◽

Tubal Factor ◽

Ayurvedic Treatment ◽

Tubal Surgery ◽

Urinary Problems

Motherhood is one of those transforming experience which can’t quite put into words. Infertility represents a major crisis for most couples, with both partners experiencing loss in ways that affect them as individu-als, as family members and as members of society as a whole. Tubal factor is second major cause of fe-male infertility. In Tubal factor, modern management are dependent on Tubal Surgery or IVF or Embryo Transfer. All these methods are the solution only for the anatomical aspect of the tube and no success in establishing the tubal function. The present case report revealed effect of Virechana and Uttarbasti karma in a known case of secondary infertility due to Fallopian Tube Blockage. Virechana is indicated in Vandhyatva and Yonivyapada chikitsa. Uttarabasti is a very important and unique Ayurvedic procedure, which is mentioned for the genito–urinary problems. Successful conception occurs after this treatment.

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The Protective Effect of Metformin against Oxandrolone-Induced Infertility in Male Rats

Current Pharmaceutical Design ◽

10.2174/1381612826666201029101524 ◽

2020 ◽

Vol 26 ◽

Author(s):

Abdulqader Fadhil Abed ◽

Yazun Bashir Jarrar ◽

Hamzeh J Al-Ameer ◽

Wajdy Al-Awaida ◽

Su-Jun Lee

Keyword(s):

Gene Expression ◽

Male Infertility ◽

Protective Effect ◽

Histological Examination ◽

Sperm Count ◽

Serum Testosterone ◽

Male Rats ◽

P Value ◽

Protective Effects ◽

Rt Pcr

Background: Oxandrolone is a synthetic testosterone analogue that is widely used among bodybuilders and athletes. However, oxandrolone causes male infertility. Recently, it was found that metformin reduces the risk of infertility associated with diabetes mellitus. Aim: This study aimed to investigate the protective effects of metformin against oxandrolone-induced infertility in male rats. Methods: Rats continuously received one of four treatments (n=7) over 14 days: control DMSO administration, oxandrolone administration, metformin administration, or co-administration of oxandrolone and metformin. Doses were equivalent to those used for human treatment. Subsequently, testicular and blood samples were collected for morphological, biochemical, and histological examination. In addition, gene expression of the testosterone synthesizing enzyme CYP11A1 was analyzed in the testes using RT-PCR. Results: Oxandrolone administration induced male infertility by significantly reducing relative weights of testes by 48%, sperm count by 82%, and serum testosterone levels by 96% (ANOVA, P value < 0.05). In addition, histological examination determined that oxandrolone caused spermatogenic arrest which was associated with 2-fold downregulation of testicular CYP11A1 gene expression. However, co-administration of metformin with oxandrolone significantly ameliorated toxicological alterations induced by oxandrolone exposure (ANOVA, P value < 0.05). Conclusion: Metformin administration protected against oxandrolone-induced infertility in male rats. Further clinical studies are needed to confirm the protective effect of metformin against oxandrolone-induced infertility among athletes.

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Ayurvedic Management of Sthaulya (Obesity): A Case Report

Journal of Ayurveda and Integrated Medical Sciences (JAIMS) ◽

10.21760/jaims.v2i4.9383 ◽

2017 ◽

Vol 2 (4) ◽

Author(s):

Nirmal P. Alodaria ◽

S. N. Gupta ◽

Dhaval Dholakiya ◽

Kaushik B. Vyas

Keyword(s):

Case Report ◽

Male Patient ◽

Life Style ◽

Health Issue ◽

Exertional Dyspnoea ◽

Alternative Approach ◽

Ayurvedic Treatment ◽

Excessive Perspiration

Obesity is burning health issue for society nowadays. In Sutrasthana of Charaka Samhita, in different Adhyaya (eg. Astauninditiya, Langhanabrumhaniya, Santarpaniya) causes, symptoms and treatment of Sthaulya are described. As an alternative approach, Ayurvedic treatment may serve as promising modality. A 17 years old male patient came in P.D. Patel Ayurveda Hospital on 22th May 2017. Patients weight was 114.8 kg and BMI was 37.51 which fairly included in obesity category according to NHI guidelines. He also had some associated complaints like exertional dyspnoea, increased appetite, excessive perspiration. He was treated with Snehana (Aabhyantara and Bahya), Swedana, Vamana, Virechana, Niruha Basti, Udvartana along with oral medicines like Varunaadi Kwatha, Arogyavardhini Vati, Triphala Guggulu, and Navayasa Lauha along with prescribed dietary regimes and life style modification. He lost about 9.7 kg of weight, which was 105.1 kgs and BMI was 34.34 only in 26 days without any complications.

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