scholarly journals A CLINICAL STUDY ON THE ROLE OF ERANDA KSHARA IN STHAULYA (OBESITY)

2015 ◽  
Author(s):  
*Borse Vilas Pundlikrao ◽  
Bhaskare Sunil A ◽  
Pawar Kiran Bhikaji ◽  
Meshram Dnyaneshwar Sudhakar
Keyword(s):  
Clinical Study ◽  
Waist Circumference ◽  
Duration Of Treatment ◽  
Average Percentage ◽  
Waist Hip Ratio ◽  
Arm Circumference ◽  
Laboratory Investigations ◽  
Basic Concepts

There are so many basic concepts in Ayurveda; Dhatvagni mandya is one of them. The whole phenomenon of disease cannot be completed without Dosha-Dushya Siddhant. They play important role in the pathology of disease. Obesity is one of them, which affect the health as well as life span. Sthaulya is one of the disease which is known to mankind since Vedic era, has been dealt in great details in Ayurvedic texts. The sign, symptoms and etiological factor of Sthaulya show very much resemblance with obesity. Worldwide Obesity is emerging health problem. It is a metabolic disorder which has affected every corner of world. In present study 30 patients of Sthaulya were selected from OPD and IPD of M.A. Podar hospital, Mumbai. These patients were undergone throw laboratory investigations. They were treated with Eranda Kshara with Ghrita bharjit Hingu given orally, duration of treatment was two months and follow up was done with parameters like Height, weight, BMI, Mid arm circumference, Waist circumference, Waist Hip ratio and symptoms of Sthaulya. It was observed that Atikshuda and Atitrushna reduce significantly. It shows relief in weight, BMI, Waist Circumference, Mid Arm Circumference and Waist Hip ratio. There was no significant change in hematological as well as Urine investigations. Average percentage of relief was 60.72%. 

Role of Shamanaushadhi in Typhoid Fever – An Observational Clinical Study

2017 ◽  
Vol 2 (2) ◽  
Author(s):  
Saurabh Parauha ◽  
M. A. Hullur ◽  
Prashanth. A. S.
Keyword(s):  
Clinical Study ◽  
Typhoid Fever ◽  
Blood Stream ◽  
Salmonella Typhi ◽  
Acute Illness ◽  
Widal Test ◽  
Risk Area ◽  
High Risk Area

Typhoid fever is an acute illness associated with fever that is most often caused by the Salmonella typhi bacteria. Once the bacteria is ingested it quickly multiplies within the stomach, liver or gall bladder and finally enters the blood stream causing symptoms like fever, headache etc. these cases as of 2010 caused about 190000 deaths up from 137000 in 1990 in whole world, India, Pakistan and Egypt are also known high risk area for developing this disease. A clinical study comprising of 15 patients of either sex attending OPD clinic of AMVH Hubli and presenting with clinical manifestation of Typhoid confirmed by Widal test were selected for observational study. All the patients received Sanjivani Vati 2 tab. bid with Kiratadisapta Kashaya (20 ml) twice daily after food. It was given for 21 days and follow up period was of 1 month with weekly visit. From the result obtained we can conclude that therapy with this Ayurvedic combination of drugs shown significant relief (p less than 0.001) in symptoms after 21 days of treatment.

scholarly journals Predictors of increasing waist circumference in an Australian population

2010 ◽  
Vol 14 (5) ◽  
pp. 870-881 ◽  
Author(s):  
Helen L Walls ◽  
Dianna J Magliano ◽  
John J McNeil ◽  
Christopher Stevenson ◽  
Zanfina Ademi ◽  
...  
Keyword(s):  
Waist Circumference ◽  
Diet Quality ◽  
Significant Proportion ◽  
Never Married ◽  
Lower Baseline ◽  
National Cohort ◽  
Behavioural Factors ◽  
Never Smokers

AbstractObjectiveTo identify predictors of increasing waist circumference (WC) over a 5-year period in a contemporary population of Australian adults.DesignLongitudinal national cohort of adults participating in the Australian Diabetes, Obesity and Lifestyle Study (AusDiab).SettingsAustralian adults in 2000 and 2005.SubjectsA total of 2521 men and 2726 women aged ≥25 years at baseline who participated in AusDiab and provided anthropometric measurements at baseline (1999–2000) and follow-up (2005).ResultsA ≥5 % increase of baseline WC occurred in 27 % of men and 38 % of women over the 5-year period. In the multivariate analysis of the total population, there was a higher risk of ≥5 % gain in baseline WC in women, younger people, people with a lower baseline WC, people who never married compared with married/de facto, current smokers compared with never smokers, people with a poorer diet quality and people with a low energy intake. However, there was no significant association with many expected predictors of waist gain such as physical activity. There were some associations between other lifestyle factors and change of WC by sex, age, level of education and across WC categories, but the associations differed across these groups.ConclusionsA ≥5 % increase of baseline WC occurred in a significant proportion of men and women over the 5-year period. Of the behavioural factors, poor diet quality was the key predictor of the ≥5 % increase of baseline WC in this cohort. The findings highlight the need to understand better the causal role of lifestyle in regard to increasing WC over time.

scholarly journals Follow-up evaluation of the immunological status of children admitted for acute cerebral nervous system infections: a retrospective study

2021 ◽  
Vol 47 (1) ◽  
Author(s):  
Giulia Spina ◽  
Bozzola Elena ◽  
Carsetti Rita ◽  
Piano Mortari Eva ◽  
Cristina Mascolo ◽  
...  
Keyword(s):  
Nervous System ◽  
Immune System ◽  
High Frequency ◽  
Immune Status ◽  
Follow Up Study ◽  
Laboratory Investigations ◽  
Pediatric Infections ◽  
Immunological Alterations

Abstract Background Acute Cerebral Nervous System Infections (ACNS) may cause death or severe complications even to promptly treated children. The role of the immune system in influencing the course and the outcome of meningitis has been studied but it is not yet completely understood. The aim of the research is to ascertain whether children who experienced ACNS infection had a normal immune system. Methods Patients under 18 years of age admitted at Bambino Gesù Children from January 2006 till June 2016 for meningitis were asked to participate to the follow-up study. The immune status was evaluated both clinically and by laboratory investigations. Results Most of the patients over 3 years at follow up had at least one immunological alteration at follow-up evaluation (74%). Considering ACNS infection etiology, certain pathogens were almost exclusive of patients affected by some immunological alteration, regardless of their age. Discussion Our preliminary results indicate that sub-clinical immunological defects may be associated to ACNS pediatric infections. Moreover, to the best of our knowledges, this is the first study correlating pathogens to immune evaluation in ACNS infections. It is, however, important to underline the high frequency of persistent immunological alterations in the analyzed patients. Further studies are needed to confirm our conclusions. Conclusions We recommend an immunological assessment at follow up evaluation in children who experienced an ACNS infection.

Active surveillance of pulmonary metastases in renal cancer patients.

2014 ◽  
Vol 32 (4_suppl) ◽  
pp. 445-445
Author(s):  
Rozana Abdul Rahman ◽  
MinYuen Teo ◽  
Noorsyakira Osman ◽  
Anuradha Jayaram ◽  
Dearbhaile M. o'Donnell ◽  
...  
Keyword(s):  
Active Surveillance ◽  
Renal Cancer ◽  
Pulmonary Metastases ◽  
Local Therapy ◽  
Mtor Inhibitors ◽  
Duration Of Treatment ◽  
Fuhrman Grade ◽  
Kaplan Meier

445 Background: Biology of pulmonary metastases (PM) in renal cancer (RCC) patients (pts) is variable and not all pts require immediate treatment. We examined the role of active surveillance in PM predominant metastatic RCC pts. Methods: Pts with a diagnosis of RCC and presence of PM were identified. PM had to be ≥ 5mms (solitary) or 2mms (multiple), classified as metastatic by the treating physician, and definitive local therapy was deemed not possible. Metastatic disease could also be present elsewhere if small volume. Pts, disease and treatment details were extracted from chart review. Kaplan-Meier method was used to perform time-to-event analyses. Primary endpoint was time on surveillance. Also studied were time from PM appearance to treatment initiation and duration of treatment. Results: Between Nov 2005 and Sept 2013, 48 pts were identified. Median age at PM diagnosis was 66 years (39 – 88 yrs), 81% were male, 94% had prior nephrectomy and were of clear cell histology. 31/45 pts (69%) had pT3 tumours with median Fuhrman grade of 3. Median MSKCC score was 1. PMs were present at diagnosis in 20 pts and developed subsequently in 27 pts at a median of 19.4 months (interquartile range (IQR) 9.5 - 64.3). Twelve (25%) of PMs were biopsy proven. 14 pts had solitary PM while 31 were multiple. Median size of metastases was 9mm (2 – 32mm). Metastases elsewhere were present in 10 pts. Median follow-up duration for all pts was 24.5 mos (IQR 12.9 – 44.1). 28/48 pts (58%) remain on surveillance at median 18.6 mos (IQR 10.6 - 28.5). In 11 pts there had been no progression while 17 pts have experienced RECIST progression of PM but remain on surveillance due to lack of symptoms/slow growth. 20/48 pts commenced on treatment. Median time from PM diagnosis to treatment was 12.5 mos (IQR 7.9 – 19.3). 18/20 pts started on VEGF TKI (Sunitinib 12 pts, Pazopanib 5, Sorafenib 1), while 2 pts had mTOR inhibitors. Median duration of follow-up on treatment was 13.4 mos (IQR 5.4 – 35.8), with 2 patients having died at 40.1 mos and 37.5 mos. Number of pts who received 2nd/3rd/4th/5th line of treatment were 7/2/2/1 respectively. Conclusions: Active surveillance of PM in RCC pts is safe and may avoid unnecessary treatment related toxicity. Once treatment is commenced, outcomes do not appear to be adversely affected.

Evaluation of homœopathic therapy in 129 asymptomatic HIV carriers

1993 ◽  
Vol 82 (01) ◽  
pp. 4-8 ◽  
Author(s):  
V.P. Singh ◽  
V. Singh ◽  
S.K. Dey ◽  
D.P. Rastogi
Keyword(s):  
Research Study ◽  
Duration Of Treatment ◽  
Immunological Status ◽  
Hiv Antibodies ◽  
Central Council ◽  
The Individual ◽  
Asymptomatic Phase ◽  
Asymptomatic Hiv

AbstractTo assess the role of homœopathic medicines in the treatment of the asymptomatic phase of HIV infection, a pilot research study was undertaken by the Central Council for Research in Homœopathy (India) starting in May 1989. 129 symptomatic HIV carriers (120 male and 9 female) were treated with homœopathic medicines on the basis of the individuals' constitutional (both mental/emotional and physical) characteristics. The medicines were prescribed in potencies varying from 30 CH to 10M and in varying dosage, depending on the age and constitution of the individual patients. 12 of the patients studied have reverted back to negative serology for HIV antibodies after treatment varying from 3 to 16 months (mean duration of treatment between entry and reversal of seroconversion for HIV antibodies 7.25 months). All patients who continue to remain symptom free are receiving follow-up treatment. Efforts are being made to evaluate their haematological and immunological status in detail.

scholarly journals The Role of Irinotecan-Bevacizumab as Rescue Regimen in Children With Low-Grade Gliomas: A Retrospective Nationwide Study in 72 Patients

2021 ◽  
Author(s):  
Charles de Marcellus ◽  
Arnault Tauziède-Espariat ◽  
Aurélie Cuinet ◽  
Claudia Pasqualini ◽  
Matthieu P. Robert ◽  
...  
Keyword(s):  
Clinical Characteristics ◽  
Low Grade ◽  
First Line ◽  
Standard Chemotherapy ◽  
Duration Of Treatment ◽  
Pilot Studies ◽  
Disease Stabilization ◽  
Line Chemotherapy

Abstract Introduction. At least half of children with low-grade glioma (LGG) treated with first line chemotherapy experience a relapse/progression and may therefore need a second-line chemotherapy. Irinotecan-bevacizumab has been recommended in this setting in France after encouraging results of pilot studies. We performed a retrospective analysis to define the efficacy, toxicity and predictors for response to the combination on a larger cohort. Methods. We reviewed the files from children < 19 years of age with progressive or refractory LGG treated between 2009 and 2016 in 7 French centers with this combination. Results. 72 patients (median age 7.8 years [range, 1-19]) received a median of 16 courses (range, 3-30). The median duration of treatment was 9 months (range, 1.4-16.2). 96% of patients experienced at least disease stabilization. The 6-month and 2-year progression-free survivals (PFS) were 91.7% [IC 95% 85.5-98.3] and 38.2% [IC 95% 28.2-51.8] respectively. No progression occurred after treatment in 18 patients with a median follow-up of 35.6 months (range, 7.6-75.9 months). Younger patients had a worse PFS (p=0.005). Prior chemoresistance, NF1 status, duration of treatment, histopathology or radiologic response did not predict response. The most frequent toxicities related to bevacizumab included grades 1-2 proteinuria in 21, epistaxis in 10, fatigue in 12 and hypertension in 8 while gastro-intestinal toxicity was the most frequent side effect related to irinotecan. Conclusion. Bevacizumab-irinotecan is highly effective for children with recurrent LGG who have failed standard chemotherapy regimens whatever their clinical characteristics, only younger children had a worse PFS.

scholarly journals Laparoscopic Extirpation of Adrenal Gland Ganglioneuroma Incidentally Diagnosed during Evaluation for Patchy Alopecia Areata in an Adolescent Boy

2019 ◽  
Vol 28 (5) ◽  
pp. 485-489
Author(s):  
Zlatan Zvizdic ◽  
Emir Haxhija ◽  
Adisa Chikha ◽  
Emir Milisic ◽  
Asmir Jonuzi ◽  
...  
Keyword(s):  
Vitamin D ◽  
Alopecia Areata ◽  
Serum Vitamin ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
Laboratory Investigations ◽  
Vitamin D Supplements ◽  
The Relationship

Objective: We present a 17-year-old boy with an incidentally diagnosed left adrenal ganglioneuroma during the diagnostic workup of alopecia areata. Clinical Presentation and Intervention: Laboratory investigations revealed vitamin D deficiency. Laparoscopic adrenalectomy was performed and ganglioneuroma was confirmed histologically. At follow-up, the vitamin D supplements improved the vitamin D levels followed by a gradual regression of alopecia areata. However, it recurred 18 months later despite the normal levels of serum vitamin D and no tumor recurrence. Conclusion: Further studies should reveal the relationship between alopecia areata and ganglioneuroma as well as the role of vitamin D in alopecia areata.

scholarly journals ROLE OF THE AGRICULTURAL INITIATIVE AND SUPPORTING AGENCIES IN THE DEVELOPMENT OF PALM GROVES IN DIWANIYA AND MUTHANNA PROVINCES

2019 ◽  
Vol 50 (4) ◽  
Author(s):  
Hamza & Naji
Keyword(s):  
Random Sample ◽  
Research Society ◽  
Research Area ◽  
Average Percentage ◽  
Palm Trees ◽  
Extension Agencies

The aim of this research is to identify the role of the agricultural initiative and the supporting devices in the development of palm orchards in Diwaniyah and Muthanna provinces. The aims of the research a questionnaire was prepared consisting (62) items distributed over (7) roles. The provinces of Diwaniyah and Muthanna were chosen for conducting the research. The owners of palm orchards benefiting from the agricultural initiative in the development of palm orchards in the provinces of Diwaniyah and Muthanna were (623) borrowers: including (294) borrowers for the establishment of modern palm groves and (329) borrowers  for the development and service of existing palm orchards. A random sample 20% was selected from the research society, with a sample of (125) namely: (59) for the establishment of a modern palm grove and (66) for the development and servicing of existing palm orchards. The results of the research found that the numbers of palm orchards established through the agricultural initiative reached (294) and the numbers of orchards developed and served were (329). The numbers of palm trees planted through the establishment of modern palm groves on agricultural initiative loans amounted to (113978) palm trees. Also, the results found the extension agencies carried out (288) extension activities related to the development of palm orchards in the research area during the agricultural initiative period. The average percentage of the extension role paragraphs was 73%. But, the average percentage of the prevention role paragraphs was 69% in the field of modern palm groves. However, 70% in the development and service of existing palm orchards and the average percentage of the follow-up role paragraphs  reached 75%. The research recommends the continuation of the agricultural initiative through the launch of a new initiative for the development of palm orchards such as the comprehensive agricultural initiative to promote the palm sector.

Psychological Resilience Provides No Independent Protection From Suicidal Risk

Crisis ◽  
2016 ◽  
Vol 37 (2) ◽  
pp. 130-139 ◽  
Author(s):  
Danica W. Y. Liu ◽  
A. Kate Fairweather-Schmidt ◽  
Richard Burns ◽  
Rachel M. Roberts ◽  
Kaarin J. Anstey
Keyword(s):  
Risk Factors ◽  
Well Being ◽  
Current Status ◽  
Psychological Resilience ◽  
Cross Sectional ◽  
Life Project ◽  
Resilience Factors ◽  
First Time

Abstract. Background: Little is known about the role of resilience in the likelihood of suicidal ideation (SI) over time. Aims: We examined the association between resilience and SI in a young-adult cohort over 4 years. Our objectives were to determine whether resilience was associated with SI at follow-up or, conversely, whether SI was associated with lowered resilience at follow-up. Method: Participants were selected from the Personality and Total Health (PATH) Through Life Project from Canberra and Queanbeyan, Australia, aged 28–32 years at the first time point and 32–36 at the second. Multinomial, linear, and binary regression analyses explored the association between resilience and SI over two time points. Models were adjusted for suicidality risk factors. Results: While unadjusted analyses identified associations between resilience and SI, these effects were fully explained by the inclusion of other suicidality risk factors. Conclusion: Despite strong cross-sectional associations, resilience and SI appear to be unrelated in a longitudinal context, once risk/resilience factors are controlled for. As independent indicators of psychological well-being, suicidality and resilience are essential if current status is to be captured. However, the addition of other factors (e.g., support, mastery) makes this association tenuous. Consequently, resilience per se may not be protective of SI.

Abusive head trauma (AHT) outcome at long-term follow-up and the role of elective neurosurgical approach: A report of 22 cases

2013 ◽  
Author(s):  
Francesca Menegazzo ◽  
Melissa Rosa Rizzotto ◽  
Martina Bua ◽  
Luisa Pinello ◽  
Elisabetta Tono ◽  
...  
Keyword(s):  
Head Trauma ◽  
Abusive Head Trauma ◽  
Long Term Follow Up
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