scholarly journals A CLINICAL EFFICACY OF VAITARANA VASTI ALONG WITH SIMHANADA GUGGULU AND RASNA SAPTAK KWATHA IN THE MANAGEMENT OF AMAVATA (RHEUMATOID ARTHRITIS)

Author(s):  
Sourabh Gupta ◽  
M.A. Hullur

Objectives: This study was conducted to evaluate the effectiveness of Vaitarana Vasti along with Simhanada Guggulu and Rasna Saptak Kwatha in the Management of Amavata (Rheumatoid Arthritis). Amavata is not only a disorder of locomotor system but is a systemic disease and is named after its chief pathogenic constituents i.e. Ama and Vata. The prolonged use of modern medicines shows some side effects and therefore an attempt was made to find an effective Ayurvedic treatment modality. Methods: A single blind clinical trial was conducted at O.P.D. and I.P.D. of Post Graduate Department of Kayachikitsa, Ayurveda Mahavidyalaya Hospital, Hubli. Vaitarana Vasti was given in followed by Shamanoushadhi Simhanada Guggulu 500mg twice and Rasna Saptak Kwatha 40ml as Anupana for 45 days with 1 month follow-up period. Results: Out of 15 Patients, 8 Patients (53.33%), 9 Patients (60%) falls under Marked Relief category of Grip strength and Tenderness respectively. 01 Subject (6.66%), 3 Patients (20%) falls under Moderate Relief category of Grip strength and Tenderness respectively. 06 Patients (40%), 2 Patients (13.33%), 12 Patients (80%) falls under Mild Relief category of Grip strength, Tenderness and E.S.R respectively. 1 subject (6.66%), 3 Patients (20%) falls under No Relief category of Tenderness and E.S.R respectively. Conclusion: Vaitarana Vasti Along With Shamanoushadhi Shamanoushadhi Simhanada Guggulu and Rasna Saptak Kwatha was found to be highly effective in Amavata and showing a way out to the individual suffering from this Amavata (Rheumatoid arthritis).

Author(s):  
Sourabh Gupta ◽  
M.A. Hullur

Amavata is a disorder where in lot of similarity is seen with Rheumatoid arthritis. This is a systemic chronic inflammatory joint disorder which affect predominantly to synovial joints. Cardiac involvement, symmetrical involvement of joints along with pain, stiffness and swelling with number of systemic complications resembles the disease Amavata. Methods: A total of 15 patients considering inclusion and exclusion criteria were selected to study Amavata in detail according to Ayurvedic texts and Rheumatoid Arthritis of modern medicine. Kshara Vasti schedule followed by Shamanoushadhi Simhanada Guggulu 500mg twice and Rasna Saptak Kwatha 40ml as Anupana for 45 days was given for 38 days with 1 month follow-up period. Results: Out of 15, 11 patients (73%) falls under marked relief category, 3 patients (20%) falls under moderate relief category and lastly 1 patient (6%) falls under mild relief category in subjective parameters. In the objective parameters, 9 patients (60%), 11 patients (73.33%) falls under marked relief category of grip strength and tenderness respectively. 03 patients (20%), 2 patients (13.33%) falls under moderate relief category of grip strength and tenderness respectively. 03 patients (20%), 2 patients (13.33%), 14 patients (93.33%) falls under mild relief category of grip strength, tenderness and E.S.R respectively. 1 subject (6.66%) falls under no relief category of E.S.R. Conclusion: All parameters of assessment but Kshara Vasti showed better improvement in the symptoms of the disease Amavata.


AYUSHDHARA ◽  
2020 ◽  
pp. 2882-2894
Author(s):  
Sourabh Gupta ◽  
M.A. Hullur

Amavata is a crippling condition where simultaneously aggravated Vata and Ama associated with each other settles in Sandhis and produce Sandhishoola, Sandhishotha, Sparshaasahitwa, which is similar to Rheumatoid Arthritis. The present study has made an attempt to find an effective Ayurvedic treatment modality through Kshara Vasti and Vaitarana Vasti along with Shamanoushadhi. A total of 30 Patients were randomly divided in two groups with 15 patients in each group. In Group A, Kshara Vasti and in Group B, Vaitarana Vasti was given in Yoga Vasti schedule followed by Shamanoushadhi Simhanada Guggulu 500mg twice and Rasna Saptak Kwatha 40ml as Anupana for 45 days in both the groups with 1 month follow-up period. Both Group A and Group B provided highly significant results in all parameters of assessment but Kshara Vasti showed better improvement in the symptoms of the disease Amavata. 63.33% of patients got marked relief, 30% of patients got moderate relief. 56.66% of patients got marked relief in grip strength and 66.66% of the total number of patients got marked relief in tenderness. All the patients of both the groups responded well after Kshara Vasti and Vaitarana Vasti and the result were highly significant. The sustained affect of Vasti was very clearly evident after administration of Vasti along with Shamanoushadhi. Hence the modalities of our treatment can be recommended to all the patients of Amavata.


2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 491.2-491
Author(s):  
M. Tada ◽  
Y. Yamada ◽  
K. Mandai ◽  
N. Hidaka

Background:We previously reported that the prevalence of sarcopenia was 28% in patients with rheumatoid arthritis (RA) in a cohort study 1. RA patients have a high risk of falls and fractures 2. However, the predictors of falls and fractures in RA patients are not known.Objectives:Whether evaluation of muscle mass and function at baseline could predict falls and fractures during four-year follow-up was investigated.Methods:The four-year follow-up data from a prospective, observational study (CHIKARA study: Correlation researcH of sarcopenIa, sKeletal muscle and disease Activity in Rheumatoid Arthritis) were used. Muscle mass was measured by a body impedance analyzer, and leg muscle mass was calculated. The leg muscle score (max: 100, min: 0) reflected the ratio of leg muscle mass to overall weight. Grip strength as an indicator of muscle function was evaluated using a digital, hand-held, isokinetic dynamometer. The correlations between muscle mass or function and falls or fractures were analyzed by survival rates and Cox hazard ratios. Leg muscle mass and grip strength were investigated by receiver operating characteristic (ROC) curve analysis for correlations with falls or fractures.Results:A total of 100 RA patients (female: 78%, mean age: 66.1 years) were enrolled; 35 patients had falls, and 19 patients had fractures during the four-year follow-up. The leg muscle score, grip strength, age, and fractures at baseline were significantly correlated with falls. The cut-off values of the leg muscle score and grip strength were calculated to be 84.5 points (sensitivity: 0.79, specificity: 0.43) and 15.9 kg (sensitivity: 0.56, specificity: 0.70), respectively, by ROC curve analysis. The patients were divided into four groups by their leg muscle scores and grip strength; the numbers of falls and fractures are shown in Table 1 for each group. The fall-free survival rate was significantly lower in the group with low leg muscle score and low grip strength (35.3%) than in the other groups (P=0.002) (Figure 1). The hazard ratio for the both low group was significantly increased, 3.6-fold (95%CI: 1.1-11.5), compared to that in the both high group.Table 1.Numbers of falls and fractures by category of leg muscle score and grip strengthLG + GS+(n=34)LG - GS+(n=12)LG + GS-(n=37)LG - GS-(n=17)P value*Falls, N6515110.010Fractures, N34660.072LG+: leg muscle score >84.5 points, GS+: grip strength >15.9kg, LG-: leg muscle score ≤84.5 points, GS+: grip strength ≤15.9kg*: compared in four groups by Kruskal-Walls test.Figure 1.Fall-free survival rate in the four groupsConclusion:RA patients with both low leg muscle score and low grip strength at baseline were at high risk for falls during the four-year follow-up period. Evaluation of muscle mass and function can predict falls in RA patients.References:[1]Tada, M., Yamada, Y., Mandai, K. & Hidaka, N. Matrix metalloprotease 3 is associated with sarcopenia in rheumatoid arthritis - results from the CHIKARA study. Int J Rheum Dis21, 1962-1969, doi:10.1111/1756-185X.13335 (2018).[2]van Staa, T. P., Geusens, P., Bijlsma, J. W., Leufkens, H. G. & Cooper, C. Clinical assessment of the long-term risk of fracture in patients with rheumatoid arthritis. Arthritis Rheum54, 3104-3112, doi:10.1002/art.22117 (2006).Disclosure of Interests:None declared


2013 ◽  
Vol 38 (6) ◽  
pp. 646-650 ◽  
Author(s):  
M. B. Larsen ◽  
A. I. Sørensen ◽  
K. L. Crone ◽  
T. Weis ◽  
M. E. H. Boeckstyns

A single-blind, randomized, controlled trial was done to compare the results of carpal tunnel release using classic incision, short incision, or endoscopic technique. In total, 90 consecutive cases were included. Follow-up was 24 weeks. We found a significantly shorter sick leave in the endoscopic group. No significant differences in pain, paraesthesiae, range of motion, pillar pain, and grip strength could be found at 24 weeks of follow-up, although intermediate significant differences were seen, especially in grip strength, in favour of endoscopic technique. No major advantage to using a short incision could be found. There were no serious complications in either group. The results indicate that the endoscopic procedure is safe and has the benefit of faster rehabilitation and return to work.


1982 ◽  
Vol 10 (4) ◽  
pp. 204-208 ◽  
Author(s):  
G Fostiropoulos ◽  
E A P Croydon

A single-blind crossover study of two non-steroidal anti-inflammatory drugs, nabumetone (1000 mg/day) and naproxen (500 mg/day) was performed in thirty patients suffering from definite or classical rheumatoid arthritis. Nabumetone significantly improved the various parameters assessed, while this was not observed with naproxen. The superiority of nabumetone over naproxen appeared for the anti-inflammatory activity (e.g. E.S.R., articular index, P.I.P. joint circumference, grip strength) as well as for the analgesic activity (patient's opinion). The clinical tolerance appeared equally good for both drugs.


2017 ◽  
Vol 06 (03) ◽  
pp. 206-215 ◽  
Author(s):  
Giovanni Munz ◽  
Giulia Guidi ◽  
Massimo Ceruso ◽  
Sandra Pfanner

Purpose The aim of this study was to evaluate the mid- to long-term outcomes and complications in patients affected by rheumatic diseases treated with the Universal 2 (U2) total wrist arthroplasty (TWA). Methods We reviewed, in a retrospective, noncontrolled cohort study, 22 patients affected by rheumatoid arthritis (RA), who underwent U2 total wrist replacement between March 2003 and January 2014 for the treatment of 23 rheumatoid wrists with the aim of obtaining the remission of pain and a range of motion (ROM) useful for daily activities, according to the patients' demands, as an alternative to total wrist arthrodesis. The cohort of patients included 20 females and 2 males, with a mean age of 54.9 years. Residual pain, preoperative ROM, postoperative ROM increases, grip strength, radiographic changes, long-term complications, and reasons for revision or failures were evaluated. Results In this study, 22 patients were evaluated at a mean follow-up of 82.3 months (range: 2–12 years). All patients had good or complete pain relief, the mean visual analogue scale pain score was 0.82. The mean grip strength improved and postoperatively was 11 kg (Jamar). The mean total ROM of flexion–extension was 72.3 degrees; radial–ulnar deviation 24.9 degrees. The mean QuickDASH score of 49 and patient rate wrist/hand evaluation of 41.7 a revision surgical procedure in six cases (26%): in two cases, a carpal component revision procedure and in four cases, total implant failures requiring either conversion to a Swanson spacer or wrist joint fusion. Conclusion TWA provides pain relief, preserves motion, and improves function in severe degenerative RA. Our results at a mid- to long-term follow-up with the U2 prosthesis were encouraging and represent, when indicated, a valid alternative to fusion which is less appealing for RA patients. Level of Evidence Level of evidence is therapeutic IV.


1999 ◽  
Vol 24 (5) ◽  
pp. 561-564 ◽  
Author(s):  
K. SCHMIDT ◽  
R. WILLBURGER ◽  
A. OSSOWSKI ◽  
R. K. MIEHLKE

After silicone arthroplasty of the metacarpophalangeal (MP) joint there is increasing osteolysis, subsidence and fracture of the implants in the longer postoperative term. In 44 patients with rheumatoid arthritis (54 hands) 151 arthroplasties of the metacarpophalangeal joint were assessed at a mean of 3.9 years postoperatively. In 57 arthroplasties titanium protectors (grommets) were used. There were no significant differences in the clinical outcomes with respect to swelling, correction of ulnar deviation, range of active movement and grip strength. The additional use of grommets in MP joint arthroplasty slightly reduced reactive osteolysis, protected the spacers from breakage and slightly reduced the amount of pain with only a few additional complications in the midterm follow-up.


1992 ◽  
Vol 20 (1) ◽  
pp. 61-77 ◽  
Author(s):  
I Caruso ◽  
S Santandrea ◽  
P Sarzi Puttini ◽  
F Montrone ◽  
L Boccassini ◽  
...  

In a prospective, randomized, single-blind study of 116 patients with early rheumatoid arthritis (mean disease duration 7 months), therapeutic activity of intra-articular rifamycin SV (525 mg/week) infiltration into each peripheral joint over 10 weeks was compared with that of 3 mg auranofin given orally twice daily. The incidence of side-effects was lower in rifamycin-treated patients. At the end of follow-up, the clinical variables and erythrocyte sedimentation rate showed a significant and persistant improvement both in 16 patients who continued the auranofin treatment regularly and in 55 treated with rifamycin who had completed the therapeutic cycle 62.5 months before; the latex test decreased only in the rifamycin group. In patients treated with auranofin or who changed to other commonly used antirheumatic agents, 57% of those with an initially negative radiological picture developed new radiological lesions in at least one of the small joints compared with 9% in the rifamycin group. Although the number of patients treated with rifamycin was small and the follow-up relatively short, the results of the study indicated that treatment with intra-articular rifamycin SV may prevent the appearance of radiological lesions in patients with early rheumatoid arthritis and normal radiographs initially.


1985 ◽  
Vol 10 (2) ◽  
pp. 199-201
Author(s):  
P. F. McCOMBE ◽  
P. J. MILLROY

A retrospective study of fifteen Swanson silastic wrist replacements for rheumatoid arthritis (fourteen cases) and osteoarthritis (one case), with a mean follow up period of 28.3 months showed an increase in function in fourteen cases and no change in one case. An increase in range of movement was present in six cases, with no change in seven. Pain was improved in fourteen cases and unchanged in one case. Grip strength was improved or unchanged in twelve cases. There were two cases of prosthesis fracture.


2015 ◽  
Vol 24 (3) ◽  
pp. 74-85
Author(s):  
Sandra M. Grether

Individuals with Rett syndrome (RS) present with a complex profile. They benefit from a multidisciplinary approach for diagnosis, treatment, and follow-up. In our clinic, the Communication Matrix © (Rowland, 1990/1996/2004) is used to collect data about the communication skills and modalities used by those with RS across the lifespan. Preliminary analysis of this data supports the expected changes in communication behaviors as the individual with RS ages and motor deficits have a greater impact.


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