scholarly journals The Relationship of Aldosterone and the Degree of Obesity in Patients with Type 2 Diabetes Mellitus Associated with Chronic Heart Failure

Author(s):  
Sh. K. Yusupova ◽  

The aim of the study was to study the relationship between aldosterone and the degree of obesity in patients with type 2 diabetes associated with chronic heart failure.The features of metabolic and hormonal disorders were studied in 65 patients with DM2 and CHF, including 29 women and 36 men.The patients were subjected to anthropometric studies (OT, OB, OT/OB, BMI). The interpretation of BMI indicators was carried out in accordance with WHO recommendations. In the studied groups of subjects, lipid fluctuations varied from normal values to their significant deviations in group 3 of patients with grade 2 obesity.The main physiological effects of aldosterone that are important in CHF are 1) sodium and fluid retention (activation of renal aldosterone receptors); 2) activation of aldosterone-dependent; 3) increased excretion of potassium and magnesium; 4) delayed excretion of norepinephrine.So, our results confirm the results of these studies and require further study.In 54.5% of patients with DM2 and CHF with obesity of the 1st degree and 81.8% of patients with obesity of the 2nd degree, an increased level of plasma aldosterone is determined, accompanied by an increased content of renin, p < 0.05

2021 ◽  
Vol 2 (1) ◽  
pp. 23-28
Author(s):  
Alexander Petra Sihite ◽  
I Gusti Ngurah Pramesemara ◽  
I Wayan Surudarma

Background: Type 2 diabetes mellitus is a metabolic disease that characterized by high blood sugar levels. This condition is often not noticed immediately and usually patient starting to realize it when complications have been occurred. A long-term complication of type 2 DM that occurred in men is erectile dysfunction (ED). ED is a condition when a person is unable to achieve or maintain an erection for sexual intercourse. One factor that influence the occurrence of ED and its severity in type 2 DM patients is the duration of the disease. Objective: The aim of this study was to determine the relationship of type 2 DM duration and the occurrence of ED. Methods: This study is an observational analytic cross-sectional study conducted at the Puskesmas (Public Health Center) Denpasar Barat I. The research data was obtained through medical record data and fill the International Index of Erectile Function (IIEF-5) questionnaire on 36 type 2 DM patients aged around 40-60 years. The statistical analysis used was Fisher's exact test. Results: The results showed that of the 36 samples, 19 (52.8%) samples had type 2 DM <24 months and 17 (47.2%) samples had type 2 DM >24 months. It was found that 5 (13.9%) samples did not experience ED while the rest experienced ED with different severity. There was a significant relationship between the type 2 DM duration and the occurrence of erectile dysfunction at Puskesmas Denpasar Barat I (p = 0.022). Conclusion: Study has found that type 2 DM patients with the longer duration (>24 months)  have a higher occurrence of ED and tended to be more severe compared to those with shorter duration (<24 months). Further studies should be performed with higher number of patients and more controlled risk factor so it will be more accurate in determining the relationship between the duration of type 2 DM and ED.


2020 ◽  
Vol 1 (1) ◽  
pp. 21-26
Author(s):  
Sri Syatriani ◽  
Yenni Purnamawati

Diabetes Mellitus is a disease that can cause complications to prevent complications can be done by maintaining the stability of blood sugar in people with diabetes. One of the efforts of patientss of Diabetes mellitus (DM) in maintaining the stability of blood sugar levels is to adhere to one of the Corneal Disease Management Programs (PROLANIS). The prevalence of diabetes mellitus in Indonesia in 2018 will reach 10.9%. The purpose of this study was to determine the relationship of compliance to follow prolanis with the stability of blood sugar levels of patientss with type 2 diabetes mellitus. This type of research is analytic research with cross sectional study design. The sample in this study were all patientss of diabetes mellitus who participated in the prolanis activities of 40 respondents at the Lumpue Health Center in Parepare City in September 2018 - January 2019 which were selected by total sampling technique. Data were analyzed by Chi-Square test. The results showed that most of the respondents included in the category of obediently followed prolanis, as many as 31 (77.5%) people and the majority with stable blood sugar, as many as 31 (77.5%) people. Relationship test results obtained p value (0,000) <α (0.05), which means there is an relationship compliance to follow Prolanis  with the stability of blood sugar in patientss with diabetes mellitus in the Lumpue Health Center in Parepare City. The conclusion of this research is that there is an relationship compliance to follow Prolanis with the stability of blood sugar. Patientss with diabetes mellitus are expected to routinely participate in prolanis activities held at each puskesmas to stabilize blood sugar levels.


PUINOVAKESMAS ◽  
2020 ◽  
Vol 1 (2) ◽  
pp. 84-93
Author(s):  
Putri Nur Cahyani ◽  
Atik Martsiningsih ◽  
Budi Setiawan

Background: People with Type 2 Diabetes Mellitus in Indonesia continue to increase in prevalence. Understanding of complications due to this disease, one of which is diabetic nephropathy or damage to kidney nephrons. Objective: To determine the relationship between HbA1c levels and creatinine levels in patients with Type 2 Diabetes Mellitus. Method: This study was an observational experiment using a cross sectional approach based on secondary data. The research was carried out in February to April 2020. The population of this research study is a member of Prolanis (Chronic Disease Management Advanced Program) in Gamping 1 Puskesmas Sleman Yogyakarta. Sample with 24 patients. Analysis of data using the Spearman’s test. Results: From the results of the normality test using the Shapiro Wilk test data obtained were not normally distributed so that continued with the Spearman rank test obtained r of -0.006 and p values with sig. (2-tailed) of 0.961 or> 0.05 (H0 received). This means that there is no relationship between HbA1c levels and blood creatinine levels in patients with type 2 DM. Conclusion: There is no relationship between HbA1c levels and creatinine levels in patients with Type 2 Diabetes Mellitus.


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