scholarly journals EFFECTIVENESS OF PURSED LIP BREATHING EXERCISE ON DYSPNOEA AMONG CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) PATIENTS

2020 ◽  
Vol 7 (3) ◽  
pp. 21-27
Author(s):  
Mrs. Mani Abhirami ◽  
Dr. C. Nalini Jeyavantha Santha
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Chronic Obstructive ◽  
Breathing Exercise ◽  
Obstructive Pulmonary Disease ◽  
Copd Patients

scholarly journals To Assess the Effectiveness of Selected Breathing Exercises among Chronic Obstructive Pulmonary Disease Patients

2021 ◽  
pp. 354-361
Author(s):  
Archana Dhengare ◽  
Savita Pohekar
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Test Score ◽  
Breathing Pattern ◽  
Chronic Obstructive ◽  
Breathing Exercise ◽  
Obstructive Pulmonary Disease ◽  
Breathing Exercises ◽  
Copd Patients ◽  
Post Test

Mortality rate of chronic obstructive pulmonary disease (COPD) is more than 3 million people every year, making it 3rd largest cause of death in the world. It has been estimated that by the year 2030. chronic obstructive pulmonary disease will become the third biggest cause of death. chronic obstructive pulmonary disease (COPD) is a progressive irreversible airway disease characterized by emphysema and chronic bronchitis, resulting in breathlessness, cough and sputum as the disease progresses, subjects with COPD experience increasing deterioration of their health-related quality of life (HRQOL), with greater impairment in their ability to work and declining participation in social and physical activities. Hence practicing pursed lip breathing exercise in their daily routine will improve their breathing pattern and quality of life. Objectives: To assess the breathing pattern of chronic obstructive pulmonary disease patient. To assess the effectiveness of selected breathing exercises among the chronic obstructive pulmonary disease patients. To associate the effectiveness of selected breathing exercises among chronic obstructive pulmonary disease patient with their demographic variables. Materials and Methods: The research approach used for the study was interventional evaluatory approach. The study was conducted in respiratory unit at Wardha City Maharashtra, India, using one group pre test post test design without control group. Non probability purposive sampling technique was used for selecting 60 COPD patients. On the first day pre test assessment of breathing pattern with the help of borg rating scale and provided pursed lip breathing exercise for 20 minutes, 2 times in a day and it was continued for 15 days followed by post test on the 15th day. The data collected, tabulated and analysed in terms of objectives of study using descriptive and inferential statistics. Results: The mean post test score. The overall comparison of selected breathing exercise among COPD patients at rest pre test score was higher 3.48 with SD of ±1.25 when compare with at rest post test score which was 0.91 with SD of ±0.85.The statistical Student’s paired t test implies that the difference in the selected breathing exercise among COPD patients was found to be 18.98 which is statistically significant at 0.05% level of significance. Also the overall comparison of selected breathing exercise among COPD patients during activity pre test score was higher 7.95 with SD of ±1.50 when compared with during activity post test score which was 2.76 with SD of ±1.02. The statistical Student’s paired t test implies that the difference in the selected breathing exercise among COPD patients was found to be 18.98 which is statistically significant at 0.05% level of significance. Hence it is statistically interpreted that effectiveness of selected breathing exercises among COPD patients at rest and during activity in post test was effective. The tabulated values was much higher than the calculated’ values at 5% level of significance, also the calculated ‘p-value which was much higher than the acceptable level of significance i.e. ‘p’=0.05. Hence the association of effectiveness of selected breathing exercises is statistically not associated with demographic variables. Conclusion: According to the results of this study, patients with Chronic Obstructive Pulmonary disease patients who practiced pursed lip breathing exercise 20 minutes, 2 times a day for 15 days had improvement of the breathing pattern which was statistically proved. Hence pursed lip breathing exercise was cost effective, non invasive, and highly feasible. Hence the researcher concluded that pursed lip breathing exercise can be practice as an effective intervention on improving breathing pattern among chronic obstructive pulmonary disease patients.

Improvement of the Functional Parameter in Patient with Chronic Obstructive Pulmonary Disease after Pulmonary Rehabilitation

2017 ◽  
Vol 6 (02) ◽  
pp. 44
Author(s):  
Arifin SWA ◽  
Indra R ◽  
Siti Chandra Widjanantie ◽  
Nury Nusdwinuringtyas
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Exercise Program ◽  
Rehabilitation Program ◽  
Functional Parameter ◽  
Chronic Obstructive ◽  
Breathing Exercise ◽  
Obstructive Pulmonary Disease ◽  
Copd Patients ◽  
6 Minute Walk Test

Background: Functional parameter in Chronic Obstructive Pulmonary Disease (COPD) can be evaluated withPeak Cough Flow (PCF), as an effective tool to measure cough ability. Patients with COPD can not do cougheffectively, that leads to sputum retention and finally functional capacity. The aimed of the study to foundimprovement of cough ability (PCF) and COPD symptom.Methods:This was a retrospective cohort study. The researcher did the measurement for PCF, COPD assesmenttool (CATTM ) score and the sixt minute walking test (6MWT) on COPD patients, after rehabilitation programthree times a week, for four weeks. The program consisted of infrared diathermy, breathing exercise, chestmobility exercise, the active cycle breathing technique and static cycle or treadmill exercise program betweenJanuary-June 2018.Results: Subjects are ten COPD patients, the mean of age was 70 years old. The data of PCF, CATTM, anddistance of 6MWT before intervention were 246± 57.19 L/ minute, 13.1± 6.36, and 296.4± 79.30. Thereforethe PCF, CATTM, and distance in 6MWT after four weeks intervention were 269 ± 70.78 (p< 0.05), 15.2 ± 8.56(p> 0.05), and 339.3 ± 62.55 (p> 0.05).Conclusion: Rehabilitation program on COPD patient along four weeks improve the PCF, however did notimprove the CATTM score and the distance of 6MWT.Keywords: 6 Minute Walk Test (6MWT), Chronic Obstructive Pulmonary Disease (COPD), COPD Assesment Test(CAT) Score, Functional Parameter, Peak Cough Flow (PCF).

Oral and Oropharyngeal Sensory Function in Adults With Chronic Obstructive Pulmonary Disease

2020 ◽  
Vol 29 (2) ◽  
pp. 864-872
Author(s):  
Fernanda Borowsky da Rosa ◽  
Adriane Schmidt Pasqualoto ◽  
Catriona M. Steele ◽  
Renata Mancopes
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Oral Cavity ◽  
Pulmonary Disease ◽  
Thermal Sensation ◽  
Sensory Function ◽  
Control Group ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Age Related ◽  
Copd Patients

Introduction The oral cavity and pharynx have a rich sensory system composed of specialized receptors. The integrity of oropharyngeal sensation is thought to be fundamental for safe and efficient swallowing. Chronic obstructive pulmonary disease (COPD) patients are at risk for oropharyngeal sensory impairment due to frequent use of inhaled medications and comorbidities including gastroesophageal reflux disease. Objective This study aimed to describe and compare oral and oropharyngeal sensory function measured using noninstrumental clinical methods in adults with COPD and healthy controls. Method Participants included 27 adults (18 men, nine women) with a diagnosis of COPD and a mean age of 66.56 years ( SD = 8.68). The control group comprised 11 healthy adults (five men, six women) with a mean age of 60.09 years ( SD = 11.57). Spirometry measures confirmed reduced functional expiratory volumes (% predicted) in the COPD patients compared to the control participants. All participants completed a case history interview and underwent clinical evaluation of oral and oropharyngeal sensation by a speech-language pathologist. The sensory evaluation explored the detection of tactile and temperature stimuli delivered by cotton swab to six locations in the oral cavity and two in the oropharynx as well as identification of the taste of stimuli administered in 5-ml boluses to the mouth. Analyses explored the frequencies of accurate responses regarding stimulus location, temperature and taste between groups, and between age groups (“≤ 65 years” and “> 65 years”) within the COPD cohort. Results We found significantly higher frequencies of reported use of inhaled medications ( p < .001) and xerostomia ( p = .003) in the COPD cohort. Oral cavity thermal sensation ( p = .009) was reduced in the COPD participants, and a significant age-related decline in gustatory sensation was found in the COPD group ( p = .018). Conclusion This study found that most of the measures of oral and oropharyngeal sensation remained intact in the COPD group. Oral thermal sensation was impaired in individuals with COPD, and reduced gustatory sensation was observed in the older COPD participants. Possible links between these results and the use of inhaled medication by individuals with COPD are discussed.

Clinical and functional peculiarities at patients with bronchial asthma, chronic obstructive pulmonary disease and overlap of asthma-chronic obstructive pulmonary disease

2020 ◽  
Vol 24 (4) ◽  
pp. 80-86
Author(s):  
V. I. Trofimov ◽  
D. Z. Baranov
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Bronchial Asthma ◽  
Blood Test ◽  
Chronic Obstructive ◽  
Inflammation Markers ◽  
Obstructive Pulmonary Disease ◽  
Copd Patients ◽  
Functional Features ◽  
Lower Airways

BACKGROUND: a comparative analysis of laboratory and instrumental tests at patients with bronchial obstructive diseases seems very actual due to the wide prevalence of these diseases. THE AIM: to evaluate characteristics of spirometry as well as allergic (total IgE, sputum eosinophils) and infectious (blood and sputum leucocytes, ESR, CRP, fibrinogen) inflammation markers at patients with bronchial obstructive diseases. PATIENTS AND METHODS: 104 case histories of patients with bronchial asthma, chronic obstructive pulmonary disease and overlap were analyzed including age, duration of smoking (pack-years), laboratory (clinical blood test, biochemical blood test, general sputum analysis, sputum culture) and instrumental (spirometry, body plethysmography, echocardiography) tests. Data were processed statistically with non-parametric methods. RESULTS: COPD patients were older than other groups’ patients, had the highest pack-years index. ACO patients were marked with maximal TLC and Raw, minimal FEV1, FEF25-75, FEV1/FVC. Patients with COPD had the highest inflammation markers (leucocyte count, CRP, fibrinogen). CONCLUSION: high active inflammation may cause severe lower airways possibility disorders at patients with COPD. Data related to a possible role of K. pneumoniaе in the pathogenesis of eosinophilic inflammation in lower airways are of significant interest. Patients with ACO occupy an intermediate position between asthma and COPD patients based on clinical and functional features.

scholarly journals LINC01414/LINC00824 genetic polymorphisms in association with the susceptibility of chronic obstructive pulmonary disease

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Xiaoman Zhou ◽  
Yunjun Zhang ◽  
Yutian Zhang ◽  
Quanni Li ◽  
Mei Lin ◽  
...  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Genetic Polymorphisms ◽  
Chronic Obstructive ◽  
Nucleotide Polymorphisms ◽  
Obstructive Pulmonary Disease ◽  
Logistic Analysis ◽  
Copd Patients ◽  
Increased Risk ◽  
And Gender

Abstract Objective Chronic obstructive pulmonary disease (COPD) is a complicated multi-factor, multi-gene disease. Here, we aimed to assess the association of genetic polymorphisms in LINC01414/ LINC00824 and interactions with COPD susceptibility. Methods Three single nucleotide polymorphisms (SNPs) in LINC01414/LINC00824 was genotyped by Agena MassARRAY platform among 315 COPD patients and 314 controls. Logistic analysis adjusted by age and gender were applied to estimate the genetic contribution of selected SNPs to COPD susceptibility. Results LINC01414 rs699467 (OR = 0.73, 95% CI 0.56–0.94, p = 0.015) and LINC00824 rs7815944 (OR = 0.56, 95% CI 0.31–0.99, p = 0.046) might be protective factors for COPD occurrence, while LINC01414 rs298207 (OR = 2.88, 95% CI 1.31–6.31, p = 0.008) risk-allele was related to the increased risk of COPD in the whole population. Rs7815944 was associated with the reduced risk of COPD in the subjects aged > 70 years (OR = 0.29, p = 0.005). Rs6994670 (OR = 0.57, p = 0.007) contribute to a reduced COPD risk, while rs298207 (OR = 7.94, p = 0.009) was related to a higher susceptibility to COPD at age ≤ 70 years. Rs298207 (OR = 2.54, p = 0.043) and rs7815944 (OR = 0.43, p = 0.028) variants was associated COPD risk among males. Rs7815944 (OR = 0.16, p = 0.031) was related to the reduced susceptibility of COPD in former smokers. Moreover, the association between rs298207 genotype and COPD patients with dyspnea was found (OR = 0.50, p = 0.016), and rs7815944 was related to COPD patients with wheezing (OR = 0.22, p = 0.008). Conclusion Our finding provided further insights into LINC01414/LINC00824 polymorphisms at risk of COPD occurrence and accumulated evidence for the genetic susceptibility of COPD.

scholarly journals Blood eosinophil count-guided corticosteroid therapy and as a prognostic biomarker of exacerbations of chronic obstructive pulmonary disease: a systematic review and meta-analysis

2021 ◽  
Vol 12 ◽  
pp. 204062232110287
Author(s):  
Tao Liu ◽  
Zi-Jian Xiang ◽  
Xiao-Meng Hou ◽  
Jing-Jing Chai ◽  
Yan-Li Yang ◽  
...  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Prognostic Biomarker ◽  
Meta Analysis ◽  
Cochrane Library ◽  
Chronic Obstructive ◽  
Blood Eosinophil ◽  
Obstructive Pulmonary Disease ◽  
Copd Patients ◽  
The Stability

Background: Chronic obstructive pulmonary disease (COPD) is characterized by persistent respiratory symptoms and dyspnea, as well as an increase in the number of leukocytes in the airways, lungs, and pulmonary vessels. A ‘One size fits all’ approach to COPD patients with different clinical features may be considered outdated. The following are the two major objectives of this meta-analysis: the first is to determine if blood eosinophil counts (BEC) can serve as a prognostic biomarker of COPD outcomes, and the second is to determine which level of BEC is effective for inhaled corticosteroid (ICS) treatment. Methods: We searched articles published before 15 May 2021 in the following four electronic databases: Web of Science, Cochrane Library, EMBASE, and PubMed. Results: A total of 42 studies, comprising a sampling of 188,710 subjects, were summarized and compared in this meta-analysis. The rate ratio (RR) of exacerbations of COPD (ECOPD) between ICS and non-ICS treatment was statistically significant for the COPD patients with a baseline BEC ⩾ 2% or ⩾ 200 cells/μl, RR = 0.82 (0.73, 0.93) or 0.79 (0.70, 0.89) respectively, while the RR of ECOPD between ICS and non-ICS treatment was statistically insignificant for the COPD patients with baseline BEC < 2% or <200 cells/μl, RR = 0.97 (0.87, 1.08) or 0.97 (0.86, 1.08), suggested that ICS therapy was beneficial to the improvement of ECOPD in patients with a baseline BEC ⩾ 2% or BEC ⩾ 200 cells/μl. Conclusion: Our research shows that a BEC ⩾ 200 cells/μl or ⩾2% is likely to become the cutoff value of ICS treatment for ECOPD. Moreover, we believe that the baseline BEC can be used as a biomarker for predicting ECOPD. The stability of BEC requires special attention.

Metabolomic profiling of anaerobic and aerobic energy metabolic pathways in chronic obstructive pulmonary disease

2021 ◽  
pp. 153537022110088
Author(s):  
Mingshan Xue ◽  
Yifeng Zeng ◽  
Runpei Lin ◽  
Hui-Qi Qu ◽  
Teng Zhang ◽  
...  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Energy Metabolism ◽  
Pulmonary Disease ◽  
Metabolic Pathways ◽  
Energy Supply ◽  
Stable Phase ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Copd Patients ◽  
Anaerobic Energy

While there is no cure for chronic obstructive pulmonary disease (COPD), its progressive nature and the formidable challenge to manage its symptoms warrant a more extensive study of the pathogenesis and related mechanisms. A new emphasis on COPD study is the change of energy metabolism. For the first time, this study investigated the anaerobic and aerobic energy metabolic pathways in COPD using the metabolomic approach. Metabolomic analysis was used to investigate energy metabolites in 140 COPD patients. The significance of energy metabolism in COPD was comprehensively explored by the Global Initiative for Chronic Obstructive Lung Disease–GOLD grading, acute exacerbation vs. stable phase (either clinical stability or four-week stable phase), age group, smoking index, lung function, and COPD Assessment Test (CAT) score. Through comprehensive evaluation, we found that COPD patients have a significant imbalance in the aerobic and anaerobic energy metabolisms in resting state, and a high tendency of anaerobic energy supply mechanism that correlates positively with disease progression. This study highlighted the significance of anaerobic and low-efficiency energy supply pathways in lung injury and linked it to the energy-inflammation-lung ventilatory function and the motion limitation mechanism in COPD patients, which implies a novel therapeutic direction for this devastating disease.

Sign in / Sign up

Export Citation Format

Share Document