scholarly journals A Rare Case of Myoid Hamartoma Masquerading As Invasive Breast Carcinoma

Author(s):  
Mohamed Shafi Mahboob ALI ◽  
◽  
Maya Mazuwin Yahya ◽  

Breast Myoid Hamartoma (MH) is a rare type of neoplasm with a poorly understood pathogenesis. Very few literatures have reported such disease with an unclear prognosis and malignant potentiality. Some isolated studies have shown that breast Myoid Hamartoma (MH) may be genetically related to other types of tumours with the involvement of HMGA2 gene. We reported a case of a 64-year-old post-menopausal lady with an underlying chronic idiopathic axonal polyneuropathy (CIAP) that was referred to our centre for a suspected right breast tumour. Clinical and imaging proved the disease to be malignant, however, core biopsy results showed otherwise. Ultrasound of the right breast showed a solid mass with a hypoechoic heterogeneous echotexture and posterior shadowing. A Mammogram highlighted a dense lesion in the right breast with radiolucent halo and macrocalcification. It was reported as BIRADS 4 category. Managing breast Myoid Hamartoma (MH) is proved to be of great challenge to clinicians as meticulous clinical acumen is needed to strategize a proper plan and management, most importantly, not to overlook the disease as the malignant transformation has been reported before.

2021 ◽  
pp. 503-505
Author(s):  
Sudeshna Nandi ◽  
Smritiparna Das ◽  
Chhanda Das ◽  
Madhumita Mukhopadhyay

Leiomyosarcoma of the kidney is a rare type of adult renal sarcoma. Here, we presented a case of a 68-year-old female who had a past history of bilateral renal calculi 3 years back with hydronephrotic changes, now presented to the OPD with complaints of abdominal pain for the past few months. On further evaluation, a heterogeneously enhancing necrotic mass was identified in the right kidney measuring 7.5 cm in the greatest dimension. A right radical nephrectomy with left Double J stenting was done. From histopathological and immunohistochemical staining, it was diagnosed as leiomyosarcoma.


2020 ◽  
Vol 14 (1) ◽  
Author(s):  
Sharifah MIA ◽  
Azwini M ◽  
Nordashima AS

Solid papillary breast carcinoma is a rare type of breast carcinoma. We present four cases which highlight the radiological and histological findings of solid papillary carcinoma. Mammogram supplemented with ultrasound played an important role in detecting solid papillary carcinomas which usually presents as intraductal lesions or intracystic mass with Doppler signal. Excision biopsy is a better option than core biopsy as the latter modality may not be representative and the diagnosis of solid papillary breast carcinoma may be missed.


2020 ◽  
Vol 4 (1) ◽  
Author(s):  
Sunil Vitthalrao Jagtap

Ameloblastic Fibrosarcoma (AFS) is an uncommon mixed odontogenic tumor composed of a benign epithelial and a malignant ectomesenchymal component. We report a case of a 15 year old female presented with a history of painful swelling over right maxilla of 6 months duration. On examination showed an irregular greyish white solid mass measuring 4.5 x 3.4 cm. On radiograph CT Neck (plain and contrast) showed mass lesion in right maxillary sinus with erosion of its floor and extending into right gingivo-buccal space. Features suggestive of neoplastic pathology. The right subtotal maxillary resection was done. On histopathological evaluation showed an irregular greyish white solid mass measuring 4.1 x 3.4 x 3.3 cm. On cut section showed grey white fleshy tumor. On histopathology reported as ameloblastic fibrosarcoma. We are presenting this extremely rare case for its clinical, radiological and histopathological features.


1997 ◽  
Vol 111 (3) ◽  
pp. 271-273 ◽  
Author(s):  
Koichi Tsunoda ◽  
Kenji Nosaka ◽  
Masabumi Housui ◽  
Emi Murano ◽  
Michiro Ishikawa ◽  
...  

AbstractWe report a rare case of laryngeal myxoma in a 57-year-old Japanese man. Except for a five-year history of gradually progressive hoarseness, he had been in good health. Video-stroboscopic examination revealed a solid mass in the anterior third of the right vocal fold. Phonosurgery performed with a microscope showed that the mass was encapsulated and located between the epithelium and vocal fold ligaments of the right vocal fold. This hard, elastic mass which measured 7 mm in diameter, was diagnosed as a myxoma. Only three cases of myxoma of the larynx have been reported in the English literature, with only one other case involving the vocal fold.


2021 ◽  
Vol 7 (3) ◽  
Author(s):  
Nazaninzahra Sepehri ◽  
Sepideh Babaniamansour ◽  
Sepideh Karkon-Shayan ◽  
Mohammadreza Majidi ◽  
Ahmadreza Atarodi ◽  
...  

Introduction: Seborrheic keratosis (SK) is one of the most common non-cancerous lesions that appears on the sun-exposure areas of the body and highly prevalent among the middle-aged population. It is the result of the hyperproliferation of keratinocytes. The clinical changes in SK lesions such as sudden growth, color changes, and ulcerations are accompanied by malignancies. Case Presentation: This study presents a rare case of giant SK on the flank part with rapid enlargement. The manifestations were in favor of malignancy and the patient underwent biopsy and total excision with a good outcome. Conclusions: Giant SK is a rare type of SK that has various similarities with malignant masses and requires further investigation.


We report a very rare case of squamous cell cancer of the right foot which had metastasize to the ipsilateral popliteal lymph node after initial diagnosis and treatment for the loco-regional disease.


2017 ◽  
Vol 24 (10) ◽  
pp. R349-R366 ◽  
Author(s):  
Catherine Zabkiewicz ◽  
Jeyna Resaul ◽  
Rachel Hargest ◽  
Wen Guo Jiang ◽  
Lin Ye

Bone morphogenetic proteins (BMPs) belong to the TGF-β super family, and are essential for the regulation of foetal development, tissue differentiation and homeostasis and a multitude of cellular functions. Naturally, this has led to the exploration of aberrance in this highly regulated system as a key factor in tumourigenesis. Originally identified for their role in osteogenesis and bone turnover, attention has been turned to the potential role of BMPs in tumour metastases to, and progression within, the bone niche. This is particularly pertinent to breast cancer, which commonly metastasises to bone, and in which studies have revealed aberrations of both BMP expression and signalling, which correlate clinically with breast cancer progression. Ultimately a BMP profile could provide new prognostic disease markers. As the evidence suggests a role for BMPs in regulating breast tumour cellular function, in particular interactions with tumour stroma and the bone metastatic microenvironment, there may be novel therapeutic potential in targeting BMP signalling in breast cancer. This review provides an update on the current knowledge of BMP abnormalities and their implication in the development and progression of breast cancer, particularly in the disease-specific bone metastasis.


2021 ◽  
Vol 108 (Supplement_2) ◽  
Author(s):  
T Arif ◽  
R Vinayagam ◽  
J M Lund ◽  
S Poonawala

Abstract Introduction Magseed is a novel localization technology in which a tiny seed is inserted to accurately mark the site of breast tumour. These can be detected intra-operatively by sentimag localization system. It aids localization of impalpable breast lesions improving margin clearance rates. Method A prospective study of first fifty Magseed localised breast tumour and axillary node excisions in Clatterbridge General Hospital. Results A total of 50 patients had 52 Magseed inserted. n = 14 was symptomatic, n = 35 was screen detected and n = 1 was an incidental finding on surveillance mammogram for a B3 lesion. 30 seeds were inserted on the right and 22 were inserted on the left (two were bilateral). 44 seeds were inserted under ultrasound guidance and the rest were targeted under stereo guidance (n = 8). Deployment of two resulted in malposition requiring wire localization. Mean age of subjects was 59.76 (range 31-81) years. Mean time to surgery after magseed insertion was 8.04 (range 1-27) days. Mean weight of the specimen was 48.57(range 10-264) gm. Mean size of the lesions was 20.32 (range 8-65) mm. Redo surgery for margin clearance was performed bringing the re-excision rate to 15.38% (n = 8). Conclusions We conclude that Magseed localization of breast tumours is a safe and reliable technique


2021 ◽  
Vol 49 (1) ◽  
pp. 030006052098465
Author(s):  
Mingyue Cui ◽  
Binfeng Xia ◽  
Heru Wang ◽  
Haihui Liu ◽  
Xia Yin

Aortopulmonary window is a rare congenital heart disease that can increase pulmonary vascular resistance, exacerbate left-to-right shunt and lead to heart failure and respiratory tract infections. Most patients die during childhood. We report a 53-year-old male patient with a large aortopulmonary window combined with anomalous origin of the right pulmonary artery from the aorta, with Eisenmenger syndrome and without surgery.


1965 ◽  
Vol 51 (6) ◽  
pp. 457-459 ◽  
Author(s):  
Leandro Gennari ◽  
Federico Bozzetti
Keyword(s):  

Intramedullary diaphyso-epiphysary lipomas of the thigh bone are extremely rare in the literature (8 cases described). A case in a 58 years old woman is reported. The tumor was localized in the right femoral bone. The same patient had previously presented a similar tumor in the subcutis of the hip and in the parotid area.


Sign in / Sign up

Export Citation Format

Share Document