scholarly journals Study of the Efficacy of Ksharaplota in Dushtavrana w.s.r to Infected Wound

2020 ◽  
Vol 11 (2) ◽  
pp. 314-321
Author(s):  
Anantkumar V Shekokar ◽  
Vijay P Ukhalkar
Keyword(s):  
Clinical Presentation ◽  
Healing Time ◽  
Control Group ◽  
Infected Wound ◽  
Group Assessment ◽  
Before And After ◽  
Group A ◽  
Level Of Significance ◽  
Group B ◽  
Vast Range

Vrana ( wound and ulcer) & process of healing is the soul of Shalyatantra Chikitsa (Surgical treatment ). Dushta Vrana means getting vitiated by Dosha & hence Dushta Vrana or infected wound is characterized by bad smell, abnormal color with profuse discharge, severe pain and longer healing time. The severity of infected wounds and their vast range of etiologies, The treatment is cleaning & dressing the wound or it can be more extensive. It may require surgical intervention to close the wound and stabilize the patient. Acharya Sushruta defines Kshara as the substance possessing Ksharana and Kshanan properties. Ksharaplota formulation was selected and applied over the affected infected wound with the help of gauze piece. During the preparation of Ksharaplota, it is coated with Snuhi kshira, Apamarga kshara & Haridra. All these drugs are Shodhana & Ropana. It was observed that Ksharaplota has the properties as sustained release of drug, absorbs discharges, less painful & easily acceptable by the patient with excellent Sodhana & Ropana Karma. The clinical study has been done on 438 patients, selected randomly and divided in two groups. Group A 220 patients i.e. trial group, were treated with local application of Ksharaplota. The Group B 218 patients i.e. control group, were treated with Gold standard. The clinical assessment was done on the basis of clinical presentation of Dushta Vrana, (Infected wound) before and after the treatment. As grading used for assessment of parameters which were ordinal in nature, “Wilcoxon Signed Ranks test” was used for within the group assessment (i.e. before and after treatment of a group). For between the group assessment of parameters, Mann Whitney – U test was applied. We had tested hypothesis for each parameter and result was interpreted accordingly. The level of significance was kept at 5% (P=0.05). And the result of the present study found significant.

EFFECT OF YOGA ON CARDIOVASCULAR EFFICIENCY

2019 ◽  
pp. 12-16
Author(s):  
Brij Bhushan Singh ◽  
Shubi Mirja ◽  
Samiya Husain
Keyword(s):  
Statistical Technique ◽  
Step Test ◽  
Control Group ◽  
Significant Difference ◽  
Post Test ◽  
Group A ◽  
Cardio Vascular ◽  
Level Of Significance ◽  
Group B ◽  
Experimental Group

The purpose of this study was to investigate the effects of yogic practices on cardio-vascular efficiency. Material and methods: Total Forty (40) subject’s boys/girls were selected as the sample of the study through the random sampling and their age ranged between 20 to 25 years from the Department of Physical Education, Aligarh Muslim University, Aligarh. The subjects were divided into two groups comprising 20 subjects in each group, namely group “A” (the experimental group) performs yogic practices (Asanas, Pranayamas and Kriyas) and group “B” (the control group) served as control. Statistical technique: for the assessment of the cardiovascular efficiency through Harvard step test pre and post-test was conducted and t-test was applied for the analysis. Result: revealed that there exist a significant difference between group A and group B, at .05 level of significance. On the basis of the pre and post-test among experimental and control group, experimental group found better than the control group on cardiovascular efficiency and significant result were found in this study.

scholarly journals PREPARATION AND EVALUATION OF CHEMICALLY INACTIVATED SALMONELLA ENTERITIDIS VACCINE IN CHICKENS

2017 ◽  
Vol 10 (11) ◽  
pp. 341
Author(s):  
Mounir M El-safty ◽  
Hala Mahmoud ◽  
Eman Sa Zaki ◽  
Howaida I Abd-alla
Keyword(s):  
Immune Responses ◽  
Salmonella Enteritidis ◽  
Serum Antibody ◽  
Enzyme Linked Immunosorbent Assay ◽  
Control Group ◽  
Chemically Induced ◽  
Before And After ◽  
Group A ◽  
Group B ◽  
Cell Envelopes

  Objective: Salmonella enteritidis ghosts (SEGs) is a non-living empty bacterial cell envelopes which were generated using a different concentration of sodium hydroxide (NaOH) 6.4 mg/mL and evaluated as a vaccine candidate in specific pathogen-free (SPF) chicken. SEGs have been produced by chemical-mediated lysis and evaluated the potential efficacy of chemically induced SEG vaccine and its ability to induce protective immune responses against virulent S. enteritidis challenge in SPF chickens.Methods: SPF chickens were divided into three groups: Group A (non-vaccinated control), Group B (vaccinated with prepared vaccine), and Group C (vaccinated with commercial vaccine).Results: Vaccination of SPF chicken with SEGs induced higher immune responses before and after virulent challenge. SPF chicken vaccinated with SEGs showed increasing in serum enzyme-linked immunosorbent assay (ELISA) antibodies. During the vaccination period, Groups B and C showed higher serum antibody titer compared to Group A. The minimal inhibitory concentration (MIC) of NaOH was capable of inducing non-living SEGs, and it has successfully generated non-living SEGs by MIC of NaOH.Conclusion: It is a one-step process which means easy manufacturing and low production cost compared to protein E-mediated lysis method. Chemically induced SEG vaccine is a highly effective method for inducing protective immunity. This study strongly suggests that SEGs will be a permissive vaccine, as the method of inhibition of S. enteritidis was safe and cheaper than other methods, and it gave a good protection.

The Role of Dialysis Membranes on Intradialytic Selenium Removal and on Selenium Status in Patients Receiving Renal Replacement Therapy

2015 ◽  
Vol 41 (1-3) ◽  
pp. 94-99 ◽  
Author(s):  
Macroui Sonikian ◽  
Artemisia Dona ◽  
Jacob Skarakis ◽  
Sophia Trompouki ◽  
Theodora Miha ◽  
...  
Keyword(s):  
Control Group ◽  
Separate Analysis ◽  
Dialysis Session ◽  
Polysulfone Membrane ◽  
Ethylene Vinyl Alcohol ◽  
Before And After ◽  
Selenium Removal ◽  
Group A ◽  
Patient Groups ◽  
Group B

Background/Aims: Dialysis membrane has been implicated in selenium (Se) deficiency in hemodialysis (HD). Intradialytic Se removal into dialysate through different membranes was investigated. Methods: We studied 19 patients on standard HD with low-flux polysulfone membrane (group A), 10 patients on standard HD with ethylene vinyl alcohol membrane (group B), 12 patients on hemodiafiltration (HDF; group C) and 16 healthy subjects (control group D). Se was measured in blood before and after dialysis session and in effluent dialysate every hour during session. Results: In all patients together, pre-dialysis serum Se levels were lower than those in control group, but, in a separate analysis, only in standard HD. In all patient groups, there was a net Se removal into dialysate but it was greater in HDF patients who, however, had similar pre-dialysis serum Se levels to those in healthy controls. Conclusion: An intradialytic Se loss was found with all 3 membrane types, but it is not the principal factor for Se depletion in HD.

scholarly journals A Randomized Controlled Trial for the Effectiveness of Aromatherapy in Decreasing Salivary Gland Damage following Radioactive Iodine Therapy for Differentiated Thyroid Cancer

2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Michihiro Nakayama ◽  
Atsutaka Okizaki ◽  
Koji Takahashi
Keyword(s):  
Thyroid Cancer ◽  
Salivary Gland ◽  
Differentiated Thyroid Cancer ◽  
Radioactive Iodine ◽  
Control Group ◽  
Parotid Glands ◽  
Before And After ◽  
Group A ◽  
Gland Function ◽  
Group B

Objective. The aim of this study was to investigate effects of aromatherapy in decreasing salivary gland damage for patients undergoing radioactive iodine (RAI) therapy with differentiated thyroid cancer (DTC). Materials and Methods. The subjects were 71 patients with DTC. They were divided into aromatherapy group (group A, n=35) and a control group (group B, n=36). We blended 1.0 mL of lemon and 0.5 mL of ginger essential oils. The patients in the inhalation aromatherapy group inhaled this blend oil and those in the control group inhaled distilled water as placebo for 10 min during admission. We statistically compared salivary gland function before and after treatment between groups A and B. Results. In comparison with group B, the rate of change of the accumulation rate was significantly higher in the parotid glands and submandibular glands of group A (P<0.05). In comparison with group B, a significant increase in rate of secretion change before and after treatment was noted in the bilateral parotid glands in group A (P<0.05). Conclusion. Because an amelioration of salivary gland function was observed in the present study, our results suggest the efficacy of aromatherapy in the prevention of treatment-related salivary gland disorder. This trial is registered with UMIN Clinical Trial Registry: UMIN000013968.

scholarly journals Comparison of the effect of two anti-adhesion materials on the formation of postoperative adhesions after myomectomy – an experimental study on rabbit does

2021 ◽  
Vol 90 (4) ◽  
pp. 407-414
Author(s):  
Soňa Pánková ◽  
Andrea Nečasová ◽  
Jana Lorenzová ◽  
Vladimír Jekl ◽  
Alois Nečas ◽  
...  
Keyword(s):  
Experimental Study ◽  
Statistical Evaluation ◽  
Scoring Systems ◽  
Control Group ◽  
Routine Practice ◽  
Postoperative Adhesions ◽  
Group A ◽  
Level Of Significance ◽  
Group B ◽  
High Level

This study compares the effect of Hyalobarrier Gel and 4DryField® PH on the formation of postoperative adhesions after myomectomy in an experimental study on rabbit does. Thirty experimental animals were divided into three groups: group A – control, group B – use of 4DryField® PH, and group C – use of the Hyalobarrier Gel. A simulated myomectomy was performed in each group. The animals were euthanised 14 days after the procedure and the antiadhesive effect of the above-mentioned preparations was evaluated according to the criteria. Statistical evaluation clearly showed differences in the antiadhesive effect in the scoring systems for groups B and C compared to control group A at a high level of significance. We demonstrated an obvious, statistically confirmed antiadhesive effect of the Hyalobarrier Gel and 4DryField® PH in an experimental model of the rabbit uterus. Comparing both preparations, the Hyalobarrier Gel shows a higher level of effectiveness. Based on the results of the experiment, both preparations can be unambiguously recommended for routine practice.

scholarly journals Protocol on Comparative Clinical Efficacy of Tryushanadi Guggul and Navaka Guggul in Sthoulya (Overweight)

2021 ◽  
pp. 169-175
Author(s):  
Ashvini Dineshrao Pardhekar ◽  
Sadhana Misar(Wajpeyi) ◽  
Vinod Ade
Keyword(s):  
Clinical Efficacy ◽  
The Body ◽  
Control Group ◽  
Arm Circumference ◽  
Before And After ◽  
Group A ◽  
Excessive Intake ◽  
Group B ◽  
Excessive Accumulation

Background: Sthoulya is Medovaha Strotodushtijanya vyadhi, which includes abnormal and excessive accumulation of Medodhatu in the body. This is caused by lack of physical and mental activity, daytime sleep, excessive intake of madhur (sweet), snigdha ahar (oily diet) results in  increase Kaphadosha and meda which results in Sthoulya (overweight) having symptoms of mild dysponea, thirst, drowsiness, excess sleep, appetite, offensive smell from the body, incapability to work and incapability to participate in sexual intercourse. Aim: Comparative clinical efficacy of Tryushanadi Guggul and Navaka Guggul in Sthoulya (overweight). Materials and methods: Total 60 patients of Sthoulya will enrolled and will divided into two groups (each group contains 30). Patients in group A (experimental group) will be given 1 gram Tryushanadi Guggul two times a day after meal with honey and in group B (control group)1 gram Navaka Guggul will administered two times a day after meal with honey for 30 days. Dietary changes and walking (30 minutes) will be advised to patients of both groups. Follow up will be taken on 15th day and 30th day. Assessment of subjective parameters like kshudrashwasa (exertional dyspnoea), swedadhikya (perspiration), atikshudha (increased appetite), nidradhikya (increased sleep) and objective parameters like body weight, B.M.I., mid arm circumference, waist-hip ratio and lipid profile will be done before and after treatment. Results: Subjective and objectives outcomes will be assessed by statistical analysis. Conclusion: It will be drawn from the result obtained.

scholarly journals A Study to Compare Effect of Hold-Relax v/s Static Stretching on Elbow Flexors Muscle Spasticity in Stroke - A Comparative Study

2021 ◽  
Vol 11 (7) ◽  
pp. 309-313
Author(s):  
Dafda Renuka H ◽  
Shah Shreya R
Keyword(s):  
Functional Independence ◽  
The Body ◽  
Control Group ◽  
Elbow Flexors ◽  
Static Stretching ◽  
Muscle Spasticity ◽  
Modified Ashworth Scale ◽  
Before And After ◽  
Group A ◽  
Group B

Background: Stroke is a condition in which Spasticity in the body musculature greatly affect the functional independence of the patients. Hold- Relax and Static Stretching is one of the useful treatment to reduce Spasticity. Aim: To find out the effect of Hold – Relax V/S Static Stretching on Elbow flexors muscle Spasticity in Stroke Patient Materials and Methods: 20 subjects were randomly allocated into two groups (Group A and Group B). For 10 subjects in Group A Control group was given Static Stretching with conventional rehab and Group B Experimental group was given Hold- Relax with conventional rehab. Treatment were given to 3 weeks 3 sets per sessions. The outcome measure used to assess the Spasticity before and after the intervention was Modified Ashworth Scale (MAS). Results and Discussion: The Hold-Relax group showed a significant reduction in Spasticity of Elbow flexors muscle, compared to the control group (p<0.05). Conclusions: Hold- Relax is more effective than Static Stretching. Key words: Stroke, Spasticity, Hold- Relax, Static Stretching, MAS.

scholarly journals Comparative Study of the Effect of Midazolam Administration Before and after Seizures on the Prevention of Complications in Children Undergoing Electroconvulsive Therapy Compared with a Control Group

2022 ◽  
Author(s):  
Mehrdad Masoudifar ◽  
Behzad Nazemroaya ◽  
Maryam Raisi
Keyword(s):  
Muscle Pain ◽  
Anterograde Amnesia ◽  
Control Group ◽  
Seizure Duration ◽  
Double Blind ◽  
Double Blind Clinical Trial ◽  
Before And After ◽  
Group A ◽  
Effective Role ◽  
Group B

Background: One of the complications of ECT treatment is headache. There is a need to use sedation during ECT. As a result, midazolam has been used to address a safe and effective strategy in this regard. Methods: This study is a double-blind clinical trial that has been performed in three groups: group A, which receives midazolam based on the usual regimen, group B, which receives midazolam after shock, and group C, which is the control group. Patients were asked about headache, nausea, and muscle aches during the recovery time, seizure duration and after becoming fully conscious. Data were analyzed in the PASW version18 software using analysis of variance and repeated measurement tests, ANOVA, independed t and χ2 tests. Results: Analysis showed that the frequency of muscle pain after full consciousness in group C was significantly higher than group B, with group B being higher than group A. χ2 test showed that the frequency of headache, cough and nausea in group C was significantly higher than the two groups A and B. Conclusion: The result of this research showed that midazolam prodrug plays an effective role in preventing post-ECT complications in children. The effect of midazolam before and after ECT on headache, muscle pain and nausea was investigated and compared with the control group. Also, due to its anterograde amnesia, midazolam can reduce the patient's stress in the next visits, and this issue is even more important when the patient is a child.

scholarly journals Risk factors of dysphagia in patients with ossification of the anterior longitudinal ligament

2020 ◽  
Vol 28 (3) ◽  
pp. 230949902096056
Author(s):  
Hirosuke Nishimura ◽  
Kenji Endo ◽  
Takato Aihara ◽  
Kazuma Murata ◽  
Hidekazu Suzuki ◽  
...  
Keyword(s):  
Cervical Vertebrae ◽  
Diffuse Idiopathic Skeletal Hyperostosis ◽  
Control Group ◽  
Anterior Longitudinal Ligament ◽  
Cervical Alignment ◽  
Maximum Thickness ◽  
Before And After ◽  
Group A ◽  
Group B ◽  
Inlet Angle

Introduction: Cervical ossification of the anterior longitudinal ligament (OALL) occasionally leads to dysphagia by the anterior osteophyte. A recent report explained that the dysphagia after an occipito-cervical fusion is caused by the narrowing of pharyngeal space due to the cranio-cervical malalignment. The purpose of this study was to evaluate the cranio-cervical alignment in patients with OALL complaining of the dysphagia. Subjects and methods: The subjects were 11 cases with complaining of dysphagia due to cervical OALL who underwent anterior cervical OALL resection and as control, age-matched 12 cases without dysphagia who have diffuse idiopathic skeletal hyperostosis in cervical spine. All subjects were male, and the mean age was 59.5 ± 9.1 years. The subjects were divided into two groups according to the symptoms of dysphagia (dysphagia, group A; control, group B). The O–C2 angle, C2–C7 angle, and the maximum thickness of OALL and the cranio-cervical alignment (pharyngeal inlet angle; PIA) and swallowing line (S-line) were measured before and after the operation on the lateral cervical radiogram at the sitting position. Results: Group A showed significantly large maximum thickness of OALL, small cervical range of motion, small O–C2 angle, large C2–C7 angle, and small PIA. The S-line crossed the anterior apex of cervical osteophyte in group A. After OALL resection, dysphagia had improved, PIA had increased, and the S-line uncrossed the apex of cervical vertebrae in all cases. Conclusion: The prevalence of dysphagia in patients with cervical OALL was influenced by the thickness of osteophyte, cervical mobility, and cranio-cervical alignment.

scholarly journals Comparative Study of Efficacy of Dhattura Beeja Ointment & Sarshapa Ointment in the Management of Vipadika (Cracked heel)

2020 ◽  
Vol 11 (4) ◽  
pp. 716-722
Author(s):  
Raju Meena ◽  
Nilima Wadnerwar ◽  
Nishigandha Jagtap
Keyword(s):  
Severe Pain ◽  
Control Group ◽  
Therapeutic Approaches ◽  
Blinded Study ◽  
Progression Of Disease ◽  
Group A ◽  
Level Of Significance ◽  
Natural Drugs ◽  
Group B ◽  
Cosmetic Problem

Background: Vipadika is one of the Vataja Nanatmaja Vikara which is also considered as Kshudra Kustha. The patient suffering with disease feel severe pain and it increases with the progression of disease. Ayurveda described various therapeutic approaches for the management of Vipadika like; Shodhana Chikitsa, Abhyantara Chikitsa and Bahya Chikitsa, etc. To provide a potent topical drug and to solve the cosmetic problem of the heel the study was undertaken. Methodology: A randomized single blinded study was designed to assess efficacy of the topical preparation made from natural drugs for the management of Vipadika. Dhattura beeja ointment and Sarshapa ointment was prepared and standardized. 15 patients were enrolled in each group. Group A received Sarshapa ointment and served as control group and group B received Dhattura beeja ointment. Both the groups were assessed for number of cracks and pain in cracks. Statistical analysis was conducted using student’s paired and unpaired t test at p<0.05 as level of significance. Result: Dhattura Beeja ointment significantly reduced number of cracks and pain associated with cracks on heel in comparison with Sarshapa ointment without any adverse effect. Conclusion: Dhattura beeja ointment is efficacious and can be used safely in the management of Vipadika.

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