scholarly journals Comparative Evaluation of Different Hand Sanitizers

2021 ◽  
Vol 68 (2) ◽  
Author(s):  
Ashwini Ramchandra Ingole ◽  
Viral Uttam Ramani ◽  
Manish Anant Kamble ◽  
Disha Motiram Dhabarde ◽  
Jagdish Radheshyam Baheti
Keyword(s):  
Antimicrobial Activity ◽  
Comparative Evaluation ◽  
The Body ◽  
Personal Hygiene ◽  
Evidence Based ◽  
Zone Of Inhibition ◽  
Standard Samples ◽  
Plate Method

Hygiene is associated with prevention of disease and promoting health. The importance of hygiene is universally recognized, and evidence based. Hands are the part of body which helps in touching various objects and surfaces and performing various works. They are involved in cooking and eating. Children and even adults are required to sanitize hands to prevent the contamination and entry of microbes in the body through hands. Bacteria associated with the hands are termed micro flora of the hands which include Propionibacterium, Staphylococcus and others which could be reduced depending on personal hygiene and environment of humans. Hand sanitizers are available in market and helps to clean and sanitize hands. The present work deals with the comparison of some brands of hand sanitizers for their antimicrobial activity. The activity is evaluated by using cup and plate method with Ciprofloxacin as a standard. Samples of four brands of sanitizers like Sterillium, IMC herbal, Savlon and Jungle Magic were prepared by diluting them. All the samples were poured in agar wells and the zone of inhibition of each sample was measured. From the study it was concluded that IMC herbal sanitizer was found to be more efficient than other sanitizers.

Synthesis and Antimicrobial Evaluation of Quinazoline-4[3H]-one Derivatives

2020 ◽  
Vol 17 ◽  
Author(s):  
Cheenu Chaudhary ◽  
Sushil Kumar ◽  
Surendra Kumar ◽  
S. Riaz Hashim
Keyword(s):  
Escherichia Coli ◽  
Antimicrobial Activity ◽  
Molecular Docking ◽  
Spectroscopic Method ◽  
Catalytic Amount ◽  
Binding Affinities ◽  
Zone Of Inhibition ◽  
Plate Method ◽  
Standard Drug ◽  
Antimicrobial Evaluation

: The present investigation aim to synthesize quinazoline-4(3H)-one derivatives (B1-10) and evaluation for their antimicrobial activity. The test compounds (B1-10) were obtained by reaction of 2-phenyl-4H-benzo[d] [1, 3]oxazin-4-one (1) with 4-aminophenol (2) to afford 3-(4-hydroxyphenyl)-2-phenylquinazoline-4(3H)-one (3) which further reacted with different N-phenylacetamide (4) in presence of anhydrous potassium carbonate and catalytic amount of potassium iodide in ethylmethylketone. The test compounds (B1-10) were characterized by spectroscopic method and evaluated for their antimicrobial activity using cup plate method by measuring zone of inhibition. Among the compounds, compound B1, B2, B4, B6 and B8 showed maximum zone of inhibition as compare with standard drug ciprofloxacin and fluconazole against Bacillus subtilis, Escherichia coli and Aspergillus niger. Molecular docking was also performed for test compounds to predict their binding affinities in the target protein and results showed good drug-like properties

scholarly journals PHYTOCHEMICAL, ANTIMICROBIAL ACTIVITY OF DIFFERENT EXTRACT OF DALBERGIA SISSOO LEAVES

2020 ◽  
Vol 11 (10) ◽  
pp. 10-11
Author(s):  
Ghumare Pramila ◽  
Dattatraya Jirekar
Keyword(s):  
Antimicrobial Activity ◽  
Aqueous Ethanol ◽  
Potential Effect ◽  
Bioactive Molecules ◽  
Dalbergia Sissoo ◽  
Proteus Vulgaris ◽  
Zone Of Inhibition ◽  
Plate Method ◽  
Traditional System ◽  
Potential Antimicrobial Activity

Traditional system of medicine consists of a greater number of plants with different medicinal and pharmacological benefits and hence represents a valuable tank of new bioactive molecules. In the present investigation, Dalbergia sissoo plants were collected from kada, District Beed, which is used widely as traditional medicine in the treatment. The study was carried out to evaluate the phytochemical and potential antimicrobial activity against five types of bacteria (Staphylococcus aureus, Salmonella typhimurium Proteus vulgaris, Pseudomonas aeruginosa and megaterium) and two fungi (Aspergillus niger and Aspergillus flavus) of five extracts. To assess the antimicrobial activity of five extracts by using Cylinder plate or cup plate method. The obtained results showed a potential effect as maximum zone of inhibition was 8 mm, 7mm and 6 mm in aqueous, ethanol and acetone extract respectively.

Doctor of Nursing Practice: Integrating Theory, Research, and Evidence-Based Practice

2013 ◽  
Vol 6 (1) ◽  
pp. 4-8 ◽  
Author(s):  
Bridget R. Roberts
Keyword(s):  
Nursing Practice ◽  
Evidence Based Practice ◽  
Strong Relationship ◽  
The Body ◽  
Evidence Based ◽  
Advanced Practice ◽  
Nursing Knowledge ◽  
Doctor Of Nursing Practice ◽  
Practice Nurses ◽  
Theory Research

A strong relationship exists between theory, research, and evidence-based practice; and these three entities are necessary to guide practice and contribute to the body of nursing knowledge. Doctor of nursing practice graduates can serve as leaders as they enter into their respective clinical practice areas. Through education of peers, along with translation and evaluation of current theoretical literature and empirical data, these advanced practice nurses can positively influence nursing practice and patient care.

scholarly journals Comparative evaluation of antimicrobial activity of three cements: new endodontic cement (NEC), mineral trioxide aggregate (MTA) and Portland

2009 ◽  
Vol 51 (3) ◽  
pp. 437-442 ◽  
Author(s):  
Mohammad Hasan Zarrabi ◽  
Maryam Javidi ◽  
Mahboube Naderinasab ◽  
Maryam Gharechahi
Keyword(s):  
Antimicrobial Activity ◽  
Comparative Evaluation ◽  
Mineral Trioxide Aggregate

DESIGN, SYNTHESIS, AND CHARACTERIZATION OF THE SOME NOVEL 2‐AMINO-PYRIDINE‐3‐ CARBONITRILE AND 2‐AMINO-4H-PYRAN‐3‐CARBONITRILE DERIVATIVES AGAINST ANTIMICROBIAL ACTIVITY AND ANTIOXIDANT ACTIVITY

2020 ◽  
pp. 125-134
Author(s):  
SURENDRA BABU LAGU ◽  
RAJENDRA PRASAD YEJELLA
Keyword(s):  
Antimicrobial Activity ◽  
Antioxidant Activity ◽  
Antimicrobial Activities ◽  
Docking Studies ◽  
Synthesis And Characterization ◽  
Zone Of Inhibition ◽  
Design Synthesis ◽  
Instrumental Methods ◽  
Objective Investigation

Objective: Investigation, the series of newer 2‐amino-pyridine‐3‐carbonitrile and 2‐amino-4H-pyran‐3‐carbonitrile derivative were synthesized and evaluated antimicrobial activities and antioxidant activity. Methods: Novel synthesized chalcones were further condensation to give 2-amino-3-cyanopyridine and 2-amino-3-cyanopyrans in the presence of malononitrile, pyridine, and ammonia acetate. The product is characterized by conventional and instrumental methods. Pyridine and 4-H-Pyran and their analogs occupy prime position due to their diverse applications. Results: The compounds A3C and B3C exhibited marked zone of inhibition with 30.02±0.02 mm and 29.06±0.01 mm, respectively. Docking studies suggested possible interactions with dihydrofolic reductase 4 with 9.15 and −9.67 kcal/mol, respectively. The IC50 30.28±0.01 exhibited A3C by 2,2-diphenylpicrylhydrazyl methods which is better among the series. The 2-amino-3-cyanopyridine derivatives were found good activity than 2-amino-3-cyanopyrane derivative. Among all synthesized compounds few having potent activity and some are near to the standard. Conclusion: Antimicrobial activity and antioxidant of the newly synthesized pyrans and pyridines derivatives will definitely inspire future researchers for the preparation of new analogs.

Abstract WP282: Protecting Stroke Patients from Aspiration and Mortality through a Bedside Aspiration Screen

Stroke ◽  
2013 ◽  
Vol 44 (suppl_1) ◽  
Author(s):  
Edith Matesic
Keyword(s):  
Organizational Learning ◽  
Aspiration Pneumonia ◽  
The Body ◽  
Kappa Statistics ◽  
Evidence Based ◽  
Stroke Patients ◽  
Rater Reliability ◽  
Stroke Treatment ◽  
Risk Of Death ◽  
The Impact

Background: Stroke patients initially experience dysphagia approximately 42-76% of the time, putting them at high risk for developing aspiration pneumonia and increasing the risk of death threefold in the first 30 days following onset of the condition. Interventions to identify risk for aspiration pneumonia are key to reducing mortality in hospitalized patients. However, no generally recognized bedside aspiration screen exists, and few have been rigorously tested. The Edith-Huhn-Matesic Bedside Aspiration Screen (EHMBAS) TM was developed as an evidence-based RN bedside aspiration screening protocol. Purpose: This study analyzed the sensitivity and inter-rater reliability of EHMBAS TM , assessed the efficacy of training methods, evaluated patient feedback, and looked at the impact of organizational learning. Methods: RNs were trained to apply the EHMBAS TM . An evaluation study assessed the sensitivity, specificity and predictability of the screen to detect aspiration in the stroke population study group. Cohen’s Kappa statistics was applied to test inter-rater reliability. Pre- and post-implementation Likert surveys examined patient and staff satisfaction on the education plan and screening process, respectively. Lastly, an analysis of organizational learning examined whether changes enhanced adherence to screening requirements. Results: Results showed that the EHMBAS TM demonstrated strong validity (94% sensitivity) and high inter-rater reliability (Kappa = .92, p<.001). Pre- and post- staff training survey results demonstrated a significant positive change in knowledge gained, feelings of preparedness, and satisfaction with teaching methods. Further, 92.3% of patients surveyed had positive screening experiences. The hospital received Silver recognition from The American Heart Association for following stroke treatment guidelines 85% of the time for at least 12 months, demonstrating the positive impact of the protocol on organizational change. Conclusions: This study contributes to the body of work aimed at establishing a reliable evidence-based, bedside aspiration screen. Patient safety is enhanced, because screen results help determine when patients can safely receive medication and nutrition by mouth.

scholarly journals Nutrition for Travel: From Jet lag To Catering

2019 ◽  
Vol 29 (2) ◽  
pp. 228-235 ◽  
Author(s):  
Shona L. Halson ◽  
Louise M. Burke ◽  
Jeni Pearce
Keyword(s):  
High Performance ◽  
Best Practice ◽  
Light Exposure ◽  
International Travel ◽  
The Body ◽  
Personal Hygiene ◽  
Jet Lag ◽  
Group Management ◽  
Food Needs ◽  
Eating Practices

Domestic and international travel represents a regular challenge to high-performance track-and-field athletes, particularly when associated with the pressure of competition or the need to support specialized training (e.g., altitude or heat adaptation). Jet lag is a challenge for transmeridian travelers, while fatigue and alterations to gastrointestinal comfort are associated with many types of long-haul travel. Planning food and fluid intake that is appropriate to the travel itinerary may help to reduce problems. Resynchronization of the body clock is achieved principally through manipulation of zeitgebers, such as light exposure; more investigation of the effects of melatonin, caffeine, and the timing/composition of meals will allow clearer guidelines for their contribution to be prepared. At the destination, the athlete, the team management, and catering providers each play a role in achieving eating practices that support optimal performance and success in achieving the goals of the trip. Although the athlete is ultimately responsible for his or her nutrition plan, best practice by all parties will include pretrip consideration of risks around the quality, quantity, availability, and hygiene standards of the local food supply and the organization of strategies to deal with general travel nutrition challenges as well as issues that are specific to the area or the special needs of the group. Management of buffet-style eating, destination-appropriate protocols around food/water and personal hygiene, and arrangement of special food needs including access to appropriate nutritional support between the traditional “3 meals a day” schedule should be part of the checklist.

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