Therapy Options Received and Impact of Pharmacist-Led Interventions on Self-Care Management of Adverse Events among Cervical Cancer Patients in a Nigerian Tertiary Hospital
The available services for the treatment of premalignant and malignant cervical cancer (CC) lesions are grossly inadequate in Nigeria. Drug-oriented self-care education programmes are lacking in our healthcare facilities. Pharmacist interventions as an expert in drug therapy management are needed. This study assessed the therapy options received and impact of pharmacist-led interventions on self-care management of AEs among CC patients in Usmanu Danfodiyo University Teaching Hospital (UDUTH), Sokoto, North-Western Nigeria. The study used a prospective longitudinal design with a 12-week patient follow-up. Instrument used was an intervieweradministered questionnaire, which was developed and pre-tested for reliability. Fifty-six eligible CC patients completed the pre- and post-interventions survey conducted over a period of eight months (From October, 2019 to May, 2020). Data analysis was done with appropriate descriptive (frequencies, percentages, means, and standard deviations) and inferential statistics (Paired sample t-test, Pearson’s Chi-square and Correlation) using SPSS Inc., Chicago, IL, USA V. 20 for windows. P< 0.05 was considered statistically significant. The mean age of the patients was 53.8±7.7years and 22(39.2%) have no formal education. Chemoradiation (CRT) and chemotherapy (CT) were the major therapy options received by the 25(44.6%) and 16 (28.6%) of the patients respectively. Before the interventions, the patients scored 57.7±18.7% and 50.8±7.1% overall mean knowledge and practice scores respectively. After the interventions, there was significant increase in the patients’ overall mean knowledge and practice, 17.6% and 6.7%, (p<0.05) scores respectively. There were significant association between patients’ age and total post-intervention knowledge (r=-0.614, p<0.001), and practice, (r=-0.424, p=0.001) scores. There were significant association between the patients’ level of education and total preand post-intervention knowledge (r=0.952, p<0.001 and