O Polypodium leucotomos no melasma: uma revisão

2020 ◽  
Vol 1 (1) ◽  
pp. 56-61
Author(s):  
Olivia Fernandes Almeida ◽  
Veronica Cristina Gomes Soares ◽  
Luana Cristina Leite de Freitas ◽  
Jorge Alberto Torres Madeiro Leite ◽  
Carlos Rocha Oliveira ◽  
...  
Keyword(s):  
Polypodium Leucotomos

Introdução: O Polypodium leucotomos possui algumas propriedades no corpo humano e principalmente na pele. Sendo utilizado como adjuvante no tratamento e prevenção de várias patologias como o melasma. Objetivo: Este estudo revisa a literatura para identificar o impacto do Polypodium leucotomos no tratamento do melasma. Material e Método: Análise de dados nas bases de artigos acadêmicos em saúde: Scielo, Medline, Lilacs com os descritores em Ciências da Saúde (DeCS): Fitoterapia; Melasma e Suplementos dietéticos, sem restrição de ano, nos idiomas português e inglês. Onde os critérios de elegibilidade, foram considerados de inclusão, os artigos originais ensaios clínicos, caso controle, revisão sistemática e metanálise, estudos em animais, in vitro e em pacientes adultos, Resultado: Foram encontrados 31 estudos, 13 foram incluídos e 18 excluídos por não atenderem os critérios de elegibilidade. Conclusão: O levantamento da literatura permitiu concluir que entre as várias propriedades do Polypodium leucotomos ha destaque para a capacidade antioxidante, anti-inflamatória, fotoprotetora e imunomoduladora, possuindo um considerável impacto na melhora da qualidade de vida dos portadores de melasma, sendo um fator clareador e protetor na doença. Porém, mais estudos clínicos randomizados devem ser realizados para confirmar seus efeitos e estabelecer a dose adequada como coadjuvante no tratamento do melasma.

Effect of Anapsos (Polypodium leucotomos extract) on in vitro production of cytokines

1997 ◽  
Vol 43 (1) ◽  
pp. 85-89 ◽  
Author(s):  
J. M. Sempere ◽  
C. Rodrigo ◽  
A. Campos ◽  
J. F. Villalba ◽  
J. Diaz
Keyword(s):  
In Vitro Production ◽  
Vitro Production ◽  
Polypodium Leucotomos

scholarly journals Effect of Anapsos (Polypodium leucotomos extract) on in vitro production of cytokines

1997 ◽  
Vol 43 (1) ◽  
pp. 85-89
Author(s):  
J. M. Sempere ◽  
C. Rodrigo ◽  
A. Campos ◽  
J. F. Villalba ◽  
J. Diaz
Keyword(s):  
In Vitro Production ◽  
Vitro Production ◽  
Polypodium Leucotomos

scholarly journals Booster Effect of a Natural Extract of Polypodium leucotomos (Fernblock®) That Improves the UV Barrier Function and Immune Protection Capability of Sunscreen Formulations

2021 ◽  
Vol 8 ◽  
Author(s):  
Jose Aguilera ◽  
Miguel Vicente-Manzanares ◽  
María Victoria de Gálvez ◽  
Enrique Herrera-Ceballos ◽  
Azahara Rodríguez-Luna ◽  
...  
Keyword(s):  
Uv Radiation ◽  
Biological Effects ◽  
Contact Hypersensitivity ◽  
Immune Protection ◽  
Protection Factor ◽  
Natural Extract ◽  
Precise Knowledge ◽  
Polypodium Leucotomos ◽  
Booster Effect

Background: Novel approaches to photoprotection must go beyond classical MED measurements, as discoveries on the effect of UV radiation on skin paints a more complex and multi-pronged scenario with multitude of skin cell types involved. Of these, photoimmunoprotection emerges as a crucial factor that protects against skin cancer and photoaging. A novel immune parameter is enabled by the precise knowledge of the wavelength and dose of solar radiation that induces photoimmunosupression. Natural substances, that can play different roles in photoprotection as antioxidant, immune regulation, and DNA protection as well as its possible ability as sunscreen are the new goals in cosmetic industry.Objective: To analyze the effect of a specific natural extract from Polypodium leucotomos (PLE, Fernblock®), as part of topical sunscreen formulations to protect from photoimmunosuppression, as well as other deleterious biological effects of UV radiation.Methods: The possible sunscreen effect of PLE was analyzed by including 1% (w/w) PLE in four different galenic formulations containing different combinations of UVB and UVA organic and mineral filters. In vitro sun protection factor (SPF), UVA protection factor (UVA-PF), contact hypersensitivity factor (CHS), and human immunoprotection factor (HIF) were estimated following the same protocol as ISO 24443:2012 for in vitro UVA-PF determination.Results: PLE-containing formulations significantly reduced UV radiation reaching to skin. Combination of UVB and UVA filters with PLE increased SPF and UVAPF significantly. PLE also increased UV immune protection, by elevating the contact hypersensitivity factor and the human immunoprotective factor of the sunscreen formulations.Conclusion: This study confirms the double role of PLE in photoprotection. Together to the biological activity shown in previous works, the UV absorption properties of PLE confers a booster effect when it is supplemented in topical sunscreens increasing the protection not only at level of erythema and permanent pigment darkening but also against two photoimmunoprotection factors.

scholarly journals Comparison of several hydrophilic extracts of Polypodium leucotomos reveals different antioxidant moieties and photoprotective effects in vitro

2018 ◽  
Vol 12 (22) ◽  
pp. 336-345 ◽  
Author(s):  
Gonzalez Salvador ◽  
R Lucena Silvia ◽  
Delgado Pablo ◽  
Juarranz Angeles
Keyword(s):  
Polypodium Leucotomos

Ultrastructural Investigations of the Contractile Filaments of Amoebae

1974 ◽  
Vol 32 ◽  
pp. 188-189
Author(s):  
P.L. Moore
Keyword(s):  
Cytoplasmic Streaming ◽  
Three Dimensional ◽  
Freeze Fracture ◽  
Amoeboid Movement ◽  
Different Types ◽  
Chemical Conditions ◽  
Complete Interpretation

Previous freeze fracture results on the intact giant, amoeba Chaos carolinensis indicated the presence of a fibrillar arrangement of filaments within the cytoplasm. A complete interpretation of the three dimensional ultrastructure of these structures, and their possible role in amoeboid movement was not possible, since comparable results could not be obtained with conventional fixation of intact amoebae. Progress in interpreting the freeze fracture images of amoebae required a more thorough understanding of the different types of filaments present in amoebae, and of the ways in which they could be organized while remaining functional.The recent development of a calcium sensitive, demembranated, amoeboid model of Chaos carolinensis has made it possible to achieve a better understanding of such functional arrangements of amoeboid filaments. In these models the motility of demembranated cytoplasm can be controlled in vitro, and the chemical conditions necessary for contractility, and cytoplasmic streaming can be investigated. It is clear from these studies that “fibrils” exist in amoeboid models, and that they are capable of contracting along their length under conditions similar to those which cause contraction in vertebrate muscles.

In Vitro Induction of Crystals of MT Protein by Vinblastine-Colcemid in Mouse Spermatids

1974 ◽  
Vol 32 ◽  
pp. 132-133
Author(s):  
John J. Wolosewick ◽  
John H. D. Bryan
Keyword(s):  
Endoplasmic Reticulum ◽  
Smooth Endoplasmic Reticulum ◽  
Nuclear Ring ◽  
Rough Er ◽  
Distal Direction ◽  
In Vitro Induction

Early in spermiogenesis the manchette is rapidly assembled in a distal direction from the nuclear-ring-densities. The association of vesicles of smooth endoplasmic reticulum (SER) and the manchette microtubules (MTS) has been reported. In the mouse, osmophilic densities at the distal ends of the manchette are the organizing centers (MTOCS), and are associated with the SER. Rapid MT assembly and the lack of rough ER suggests that there is an existing pool of MT protein. Colcemid potentiates the reaction of vinblastine with tubulin and was used in this investigation to detect this protein.

Induction and Differentiation of Dental Epithelium in Vivo and in Vitro

1982 ◽  
Vol 40 ◽  
pp. 142-145
Author(s):  
E. J. Kollar
Keyword(s):  
Connective Tissue ◽  
Oral Mucosa ◽  
Basal Lamina ◽  
Functional Derivatives ◽  
Specific Source ◽  
Dental Epithelium ◽  
Connective Tissue Stroma

The differentiation and maintenance of many specialized epithelial structures are dependent on the underlying connective tissue stroma and on an intact basal lamina. These requirements are especially stringent in the development and maintenance of the skin and oral mucosa. The keratinization patterns of thin or thick cornified layers as well as the appearance of specialized functional derivatives such as hair and teeth can be correlated with the specific source of stroma which supports these differentiated expressions.

Immunoenzymatic demonstration of the simultaneous presence of transferrin, hemopexin and albumin in a same hepatocyte and their ultrastructural localization

1978 ◽  
Vol 36 (2) ◽  
pp. 88-89
Author(s):  
M. Kraemer ◽  
J. Foucrier ◽  
J. Vassy ◽  
M.T. Chalumeau
Keyword(s):  
Plasma Proteins ◽  
Rat Hepatocytes ◽  
Ultrastructural Localization ◽  
Carrier Proteins ◽  
Normal Cells ◽  
Adult Rat ◽  
Adult Rat Hepatocytes ◽  
Monospecific Antisera ◽  
Different Levels

Some authors using immunofluorescent techniques had already suggested that some hepatocytes are able to synthetize several plasma proteins. In vitro studies on normal cells or on cells issued of murine hepatomas raise the same conclusion. These works could be indications of an hepatocyte functionnal non-specialization, meanwhile the authors never give direct topographic proofs suitable with this hypothesis.The use of immunoenzymatic techniques after obtention of monospecific antisera had seemed to us useful to bring forward a better knowledge of this problem. We have studied three carrier proteins (transferrin = Tf, hemopexin = Hx, albumin = Alb) operating at different levels in iron metabolism by demonstrating and localizing the adult rat hepatocytes involved in their synthesis.Immunological, histological and ultrastructural methods have been described in a previous work.

Sem Studies of Co-Cr-Mo Surgical Implant Alloy Corrosion Behavior

1982 ◽  
Vol 40 ◽  
pp. 520-521
Author(s):  
Ann Chidester Van Orden ◽  
John L. Chidester ◽  
Anna C. Fraker ◽  
Pei Sung
Keyword(s):  
Electron Microscopy ◽  
Corrosion Behavior ◽  
Anodic Polarization ◽  
Saline Solution ◽  
Saturated Calomel Electrode ◽  
Physiological Saline ◽  
X Ray ◽  
Physiological Saline Solution ◽  
Scanning Electron

The influence of small variations in the composition on the corrosion behavior of Co-Cr-Mo alloys has been studied using scanning electron microscopy (SEM), energy dispersive x-ray analysis (EDX), and electrochemical measurements. SEM and EDX data were correlated with data from in vitro corrosion measurements involving repassivation and also potentiostatic anodic polarization measurements. Specimens studied included the four alloys shown in Table 1. Corrosion tests were conducted in Hanks' physiological saline solution which has a pH of 7.4 and was held at a temperature of 37°C. Specimens were mechanically polished to a surface finish with 0.05 µm A1203, then exposed to the solution and anodically polarized at a rate of 0.006 v/min. All voltages were measured vs. the saturated calomel electrode (s.c.e.).. Specimens had breakdown potentials near 0.47V vs. s.c.e.

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