scholarly journals Pattern of Uropathogens and Antibiotics Susceptibility in a Tertiary Hospital in North-Western Nigeria

2020 ◽  
Vol 1 (2) ◽  
Author(s):  
Abubakar Sadiq Muhammad ◽  
Mohammad Yahya ◽  
Uzodimma Unwuasonya ◽  
Muhammad Ujudud Musa ◽  
Haliru Sirajo Tambuwal ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Urinary Tract ◽  
Tract Infection ◽  
Urinary Tract Obstruction ◽  
Tertiary Hospital ◽  
Klebsiella Pneumonia ◽  
Indwelling Catheter ◽  
Urogenital Tract Infection ◽  
Antibiotics Susceptibility ◽  
North Western

Background: A uropathogen is a microorganism capable of causing urogenital tract infection (UGI). The most common uropathogens are Escherichia coli, Pseudomonas aeruginosa, Proteus mirabilis and Klebsiella pneumonia. They lead to UGI in patients with urinary tract obstruction, indwelling catheter/stent, elderly and patients with immunosuppression. There is increasing resistance to commonly used antibiotics due to empirical misuse of antibiotics The objective of this study is to document pattern of uropathogen and their antibiotics susceptibility in our hospital. Materials and methods: This is a retrospective study of consecutive urological patients with features of urinary tract infection (UTI) in our hospital from June 2017 to June 2018. Data was collected using a semi-structured proforma and analysed using SPSS version 20.0 for windows. Results were reported in percentages and mean ± standard deviation. Results: There were 126

scholarly journals Retracted: Occurrence of Multidrug Resistance Escherichia coli and Other Bacteria Species Associated with Urinary Tract Infection in Two Geopolitical Zones of Ondo State, Nigeria

2019 ◽  
pp. 1-8
Author(s):  
Titilayo Modupe Waire ◽  
Timothy Olubisi Adejumo ◽  
Festus Abiose Olajubu
Keyword(s):  
Escherichia Coli ◽  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Antimicrobial Agents ◽  
Early Morning ◽  
E Coli ◽  
Microbiological Methods ◽  
Retraction Notice ◽  
Antibiotics Susceptibility

Urinary tract infection (UTI) is a common bacterial infection known to affect different parts of the urinary tract of both male and female. Escherichia coli has been found to be responsible for causing 80% to 90% of the infection. An investigation was carried out to determine the prevalence of bacteria, especially E. coli implicated in UTI, and to ascertain their antibiotics susceptibility pattern. Early morning mid-stream urine samples were collected from 250 patients aged 18 to 60 years, between March and July of 2016 from 5 major Hospitals in the study location. The isolates were identified using standard microbiological methods and susceptibility tests were carried out using ten antibiotics. Results showed that 65(30.7%) of the isolates were E. coli. Followed by Pseudomonas aeruginosa 45(21.2%), Klebsiella pneumoniae 42(19.8%), Staphylococcus aureus 32(15.1%) and Proteus mirabilis 28(13.2%). The percentages of resistance of E. coli isolates to antimicrobial agents were chloramphenicol (64.9%), sparfloxacin (59.5%), ciprofloxacin (73.0%), septrin (73.0%), amoxacillin (91.9%), augmentin (83.8%), gentamycin (48.7%), perfloxacin (40.5%), ofloxacin (40.5%) and streptomycin (54.1%). The need for constant antimicrobial susceptibility surveillance by health managements system that will help clinicians to provide safe and effective therapy is advocated. Retraction Notice: This paper has been retracted from the journal. This journal is determined to promote integrity in research publication. This retraction is in spirit of the same. After formal procedures editor(s) and publisher have retracted this paper on 10th July 2019. Related policy is available here: http://goo.gl/lI77Nn

scholarly journals Incidence of Urinary Tract Infection among Diabetic Patients in Abakaliki Metropolis

2020 ◽  
pp. 117-121
Author(s):  
Stella Chinenye Kama ◽  
Emmanuel Ifeanyi Obeagu ◽  
M. N. Alo ◽  
Kingsley Chinedum Ochei ◽  
Uchenna Modestus Ezugwu ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
University Teaching ◽  
Klebsiella Pneumonia ◽  
Urine Specimen ◽  
Diabetic Patients ◽  
Age Group ◽  
Tract Infections

The investigation of urinary tract infection (UTI) among diabetic patients 15-51 years and above was assessed using 100 mid-stream urine specimen with the objective of isolating and identifying different types of bacteria and their respective frequencies among diabetic patients attending diabetic clinic at Alex Ekwueme Federal University Teaching Hospital, Abakaliki. A urine culture was performed combined with a full report of urine to establish the diagnosis. The result showed that the majority of bacteria in urinary tract infections were in 27-32 years of age group (71.4%) and lowest in 15-20 years age group (0%). The predominant bacteria isolates and their percentage occurrences include; Escherichia coli (39.13%), Klebsiella pneumonia (21.74%), Proteus (8.69%), Pseudomonas aeruginosa (8.69%), Streptococcus (8.69%), Staphylococcus aureus (6.52%), Enterococcus faecalis (4.25%). There was a high prevalence of the isolated organisms in female (47.7%) compared to males (36%). It follows that most predominant agent of UTI in diabetic patients in Abakaliki Metropolis is Escherichia coli followed by Klebsiella pneumonia.

scholarly journals Urinary Tract Infection in Omani Children: Etiology and Antimicrobial Resistance. A Comparison between First Episode and Recurrent Infection

2021 ◽  
pp. 51-62
Author(s):  
Mohamed El-Naggari ◽  
Sharef Al-Mulaabed ◽  
Fatma Rabah ◽  
Ahmed B. Idrees ◽  
Zakaria Al Muharrmi ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Recurrent Urinary Tract Infection ◽  
University Hospital ◽  
Klebsiella Pneumonia ◽  
Close Monitoring ◽  
Gulf Region ◽  
Extended Spectrum

Aims: The aims of this study were identification of the causative organisms, uropathogens’ resistance, and extended-spectrum β-lactamase producing bacteria in primary and recurrent urinary tract infection. Study Design: A retrospective study included Omani children, less than 14 years, with any documented urinary tract infection. Place and Duration of Study: Sultan Qaboos University Hospital between September 2008 and August 2012. Methodology: Comparison was made between both groups using Chi-squared (χ2) test as appropriate. Results: The first group included 175 children with first attack of urinary tract infection. Escherichia coli was the leading pathogen (69%), Klebsiella pneumonia (17%; P<0.001), and extended-spectrum β-lactamase producing bacteria (3%). 230 isolated uropathogens from 74 patients with recurrent urinary tract infection. The most common isolated pathogen was Escherichia coli 187 (81.3%; P<0.001), followed by Klebsiella pneumonia 12 (5.1%), and extended-spectrum β-lactamase producing bacteria (7%; P=0.042). Overall resistance to parenteral antibiotics was less evident than oral antibiotics, with least resistance to Meropenem and Imipenem (1% each). Higher resistance was found in recurrent urinary tract infection to Augmentin, Cefuroxime, Ceftriaxone, and Cefotaxime. Oral Nitrofurantoin showed least resistance in first and recurrent urinary tract infection, but increased in non- Escherichia coli uropathogens. Conclusion: Escherichia coli and ESBL were more common in recurrent urinary tract infection, while Klebsiella pneumonia were found more in first urinary tract infection. Meropenem, Imipenem, Amikacin, and Piperacillin/Tazobactam can be used cautiously and selectively, while Cefotaxime and Ceftriaxone cannot be used in both groups. Our report shows high resistance rates to Ampicillin, Cefuroxime, and Amoxicillin/Clavulanate. First-generation cephalosporin is not recommended for use as empiric therapy. We recommend the use of Ciprofloxacin and Nitrofurantoin as empiric treatment in both groups, with close monitoring of clinical response. Indeed, a larger scale multicenter national and regional studies are recommended in Oman and gulf region.

scholarly journals Prevalence and Multidrug Resistance Pattern of E. Coli among Urinary Tract Infection Patients in Tertiary Care Hospital of Multan

2021 ◽  
Vol 8 (4) ◽  
pp. 104-112
Author(s):  
Hubza Ruatt Khan ◽  
Mehvish Javeed ◽  
Asghar Javed ◽  
Nisma Farooq
Keyword(s):  
Escherichia Coli ◽  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Antimicrobial Resistance ◽  
Tract Infection ◽  
Tertiary Care ◽  
Klebsiella Pneumonia ◽  
Care Hospital ◽  
Effective Prevention ◽  
E Coli

Urinary Tract Infection is alarming problem worldwide due to the intensity of antimicrobial resistance. Escherichia coli is the most predominant organism in UTI. This study was planned to evaluate demographic parameters, the prevalence of E. coli, and antimicrobial resistance patterns among E. coli isolates from UTI patients in Nishtar Hospital of Multan from January to June 2018. A total of 350 mid-stream urine samples were collected from different patients having age group from 25 to 60 years and processed by standard laboratory procedures. Out of 350 samples, 100 samples were observed as critical bacteremia. Escherichia coli and Klebsiella pneumonia were the most persistent (47 % and 19 % individually) among the Gram-negative pathogens followed by S. aureus (14 %), Enterobacter spp. (11 %) and Candida (9 %) respectively. The incidence of UTI was found higher in 25-35 age groups. The prevalence of UTI with E. coli as an infectious agent was 72 % in females, and 28 % in males. The prevalence of E. coli was more in rural areas (70 %) than in urban areas (26 %). The antimicrobial testing against E. coli showed the highest resistance to amoxicillin (65.9 %) and ciprofloxacin (38.2 %), whereas highly sensitive rate observed against Fosfomycin (FOS) (95.7 %), Gentamicin (GEN) (89.3 %), and Nitrofurantoin (NIT) (85 %) respectively. The increased resistance against ampicillin and ciprofloxacin was observed in Multan have a great emerging problem so there is a need for effective prevention strategies for the E. coli drug resistance and successful surveillance required to be improved.

scholarly journals Escherichia coli bacteremia due to urinary tract infection complicated by acute myocarditis: A rare complication

2021 ◽  
Vol 9 ◽  
pp. 2050313X2110236
Author(s):  
Mohamadanas Oudih ◽  
Thana Harhara
Keyword(s):  
Escherichia Coli ◽  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Acute Myocarditis ◽  
Rare Complication ◽  
Kidney Injury ◽  
St Segment Elevation ◽  
Infection Treatment ◽  
St Segment

Acute myocarditis is a rare complication of Escherichia coli urinary tract infection and sepsis. We report the case of a previously healthy 55-year-old female who presented to our emergency department with diarrhea and hypotension. The basic metabolic panel results showed an increase in inflammatory markers and an acute kidney injury. Urine and blood cultures grew Escherichia coli. The patient subsequently developed sudden chest pain and shortness of breath, diffuse ST-segment elevation, and cardiac enzymes’ elevation. Coronary angiogram was normal, and transthoracic echocardiogram demonstrated normal ventricular functions. Cardiac magnetic resonance imaging was highly suspicious of myopericarditis. The patient made a full recovery after infection treatment with intravenous antibiotics, aspirin, and colchicine.

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